Page last updated: 2024-10-30

lansoprazole and Hyperplasia

lansoprazole has been researched along with Hyperplasia in 9 studies

Lansoprazole: A 2,2,2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS. Lansoprazole is a racemic mixture of (R)- and (S)-isomers.

Hyperplasia: An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.

Research Excerpts

ExcerptRelevanceReference
" The aim of this study was to assess the long-term safety of vonoprazan for maintenance treatment of healed erosive oesophagitis versus lansoprazole."9.69Randomised clinical trial: 3-year interim analysis results of the VISION trial to evaluate the long-term safety of vonoprazan as maintenance treatment in patients with erosive oesophagitis. ( Akiyama, J; Aoyama, N; Haruma, K; Kanoo, T; Kinoshita, Y; Kushima, R; Kusumoto, N; Miyata, K; Uemura, N; Yao, T, 2023)
" pylori infection on gastritis, enterochromaffin-like cell density and hyperplasia, mucosal atrophy and serum gastrin in patients with gastric hypersecretion (basal acid output gt; 15 mmol/h) with either hypergastrinemia (Zollinger-Ellison syndrome) or normal gastrin (non-Zollinger-Ellison syndrome) before and during long-term treatment with lansoprazole."7.71Helicobacter pylori effects on gastritis, gastrin and enterochromaffin-like cells in Zollinger-Ellison syndrome and non-Zollinger-Ellison syndrome acid hypersecretors treated long-term with lansoprazole. ( Haber, MM; Hirschowitz, BI, 2001)
" pylori represents an important factor for the progression of fundic gastritis and the development of argyrophil cell hyperplasia during long-term treatment with lansoprazole."7.69Gastric mucosa during treatment with lansoprazole: Helicobacter pylori is a risk factor for argyrophil cell hyperplasia. ( Arnold, R; Brunner, G; Eissele, R; Simon, B; Solcia, E, 1997)
" The aim of this study was to assess the long-term safety of vonoprazan for maintenance treatment of healed erosive oesophagitis versus lansoprazole."5.69Randomised clinical trial: 3-year interim analysis results of the VISION trial to evaluate the long-term safety of vonoprazan as maintenance treatment in patients with erosive oesophagitis. ( Akiyama, J; Aoyama, N; Haruma, K; Kanoo, T; Kinoshita, Y; Kushima, R; Kusumoto, N; Miyata, K; Uemura, N; Yao, T, 2023)
" pylori infection on gastritis, enterochromaffin-like cell density and hyperplasia, mucosal atrophy and serum gastrin in patients with gastric hypersecretion (basal acid output gt; 15 mmol/h) with either hypergastrinemia (Zollinger-Ellison syndrome) or normal gastrin (non-Zollinger-Ellison syndrome) before and during long-term treatment with lansoprazole."3.71Helicobacter pylori effects on gastritis, gastrin and enterochromaffin-like cells in Zollinger-Ellison syndrome and non-Zollinger-Ellison syndrome acid hypersecretors treated long-term with lansoprazole. ( Haber, MM; Hirschowitz, BI, 2001)
" pylori represents an important factor for the progression of fundic gastritis and the development of argyrophil cell hyperplasia during long-term treatment with lansoprazole."3.69Gastric mucosa during treatment with lansoprazole: Helicobacter pylori is a risk factor for argyrophil cell hyperplasia. ( Arnold, R; Brunner, G; Eissele, R; Simon, B; Solcia, E, 1997)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (33.33)18.2507
2000's3 (33.33)29.6817
2010's2 (22.22)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Haruma, K1
Kinoshita, Y1
Yao, T1
Kushima, R1
Akiyama, J1
Aoyama, N1
Kanoo, T1
Miyata, K1
Kusumoto, N1
Uemura, N1
East, JE1
Vieth, M2
Rex, DK1
Matsuzaki, J1
Suzuki, H1
Minegishi, Y1
Sugai, E1
Tsugawa, H1
Yasui, M1
Hibi, T1
Fukushima, Y1
Shindo, T1
Anai, M1
Saitoh, T1
Wang, Y1
Fujishiro, M1
Ohashi, Y1
Ogihara, T1
Inukai, K1
Ono, H1
Sakoda, H1
Kurihara, Y1
Honda, M1
Shojima, N1
Fukushima, H1
Haraikawa-Onishi, Y1
Katagiri, H1
Shimizu, Y1
Ichinose, M1
Ishikawa, T1
Omata, M1
Nagai, R1
Kurihara, H1
Asano, T1
Eissele, R1
Brunner, G1
Simon, B1
Solcia, E1
Arnold, R1
Suzuki, S2
Ohkusa, T2
Shimoi, K2
Horiuchi, T2
Fujiki, K2
Takashimizu, I2
Sakurazawa, T1
Ariake, K1
Ishii, K1
Kumagai, J1
Tanizawa, T1
Hirschowitz, BI1
Haber, MM1
Stolte, M1
Schmitz, JM1
Alexandridis, T1
Seifert, E1

Reviews

1 review available for lansoprazole and Hyperplasia

ArticleYear
Serrated lesions in colorectal cancer screening: detection, resection, pathology and surveillance.
    Gut, 2015, Volume: 64, Issue:6

    Topics: Adenomatous Polyposis Coli; Colonic Polyps; Colonoscopy; Colorectal Neoplasms; Early Detection of Ca

2015

Trials

3 trials available for lansoprazole and Hyperplasia

ArticleYear
Randomised clinical trial: 3-year interim analysis results of the VISION trial to evaluate the long-term safety of vonoprazan as maintenance treatment in patients with erosive oesophagitis.
    BMC gastroenterology, 2023, May-01, Volume: 23, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Double-Blind Method; Esophagitis; Humans

2023
Disappearance of hyperplastic polyps in the stomach after eradication of Helicobacter pylori. A randomized, clinical trial.
    Annals of internal medicine, 1998, Nov-01, Volume: 129, Issue:9

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Abietanes; Adult; Aged; Amoxicillin; Anti-Bacterial Agents;

1998
Effects of long-term treatment with proton pump inhibitors in gastro-oesophageal reflux disease on the histological findings in the lower oesophagus.
    Scandinavian journal of gastroenterology, 2000, Volume: 35, Issue:11

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Barrett Esophagus; Double-Blind Method;

2000

Other Studies

5 other studies available for lansoprazole and Hyperplasia

ArticleYear
Acid suppression by proton pump inhibitors enhances aquaporin-4 and KCNQ1 expression in gastric fundic parietal cells in mouse.
    Digestive diseases and sciences, 2010, Volume: 55, Issue:12

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Aquaporin 4; Blotting, Western; Cell Differentiati

2010
Structural and functional characterization of gastric mucosa and central nervous system in histamine H2 receptor-null mice.
    European journal of pharmacology, 2003, May-02, Volume: 468, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Blotting, Northern; Electroshock; Gastric Acid; Ga

2003
Gastric mucosa during treatment with lansoprazole: Helicobacter pylori is a risk factor for argyrophil cell hyperplasia.
    Gastroenterology, 1997, Volume: 112, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Female; Gastric Mucosa; Gastrins; Gastritis; H

1997
Disappearance of multiple hyperplastic polyps after the eradication of Helicobacter pylori.
    Gastrointestinal endoscopy, 1997, Volume: 46, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Bacterial Agents; Drug Therapy, Combinati

1997
Helicobacter pylori effects on gastritis, gastrin and enterochromaffin-like cells in Zollinger-Ellison syndrome and non-Zollinger-Ellison syndrome acid hypersecretors treated long-term with lansoprazole.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Enterochromaffin-like Cells; Enzyme Inhibitors; Fema

2001