lansoprazole has been researched along with Heart Failure in 1 studies
Lansoprazole: A 2,2,2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS. Lansoprazole is a racemic mixture of (R)- and (S)-isomers.
Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here, we investigated the effects of lansoprazole on cardiac hypertrophy and heart failure, as well as the underlying mechanisms." | 7.96 | Lansoprazole alleviates pressure overload-induced cardiac hypertrophy and heart failure in mice by blocking the activation of β-catenin. ( Bin, J; Chen, L; Chen, Z; Kitakaze, M; Li, Y; Liao, W; Liao, Y; Lin, H; Wang, Q; Wang, Y; Zheng, C; Zhu, H; Zhu, Y, 2020) |
| " Here, we investigated the effects of lansoprazole on cardiac hypertrophy and heart failure, as well as the underlying mechanisms." | 3.96 | Lansoprazole alleviates pressure overload-induced cardiac hypertrophy and heart failure in mice by blocking the activation of β-catenin. ( Bin, J; Chen, L; Chen, Z; Kitakaze, M; Li, Y; Liao, W; Liao, Y; Lin, H; Wang, Q; Wang, Y; Zheng, C; Zhu, H; Zhu, Y, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lin, H | 1 |
| Li, Y | 1 |
| Zhu, H | 1 |
| Wang, Q | 1 |
| Chen, Z | 1 |
| Chen, L | 1 |
| Zhu, Y | 1 |
| Zheng, C | 1 |
| Wang, Y | 1 |
| Liao, W | 1 |
| Bin, J | 1 |
| Kitakaze, M | 1 |
| Liao, Y | 1 |
1 other study available for lansoprazole and Heart Failure
| Article | Year |
|---|---|
Lansoprazole alleviates pressure overload-induced cardiac hypertrophy and heart failure in mice by blocking the activation of β-catenin.
Topics: Animals; Aorta; beta Catenin; Cell Proliferation; Cells, Cultured; Constriction; Disease Models, Ani | 2020 |