Page last updated: 2024-10-30

lansoprazole and Headache

lansoprazole has been researched along with Headache in 10 studies

Lansoprazole: A 2,2,2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS. Lansoprazole is a racemic mixture of (R)- and (S)-isomers.

Headache: The symptom of PAIN in the cranial region. It may be an isolated benign occurrence or manifestation of a wide variety of HEADACHE DISORDERS.

Research Excerpts

ExcerptRelevanceReference
"As can be expected, headache was reported less frequently in this study compared with clinical trials with lansoprazole."9.10Determinants of headache in lansoprazole users in The Netherlands: results from a nested case-control study. ( Claessens, AA; Heerdink, ER; Lamers, CB; Leufkens, HG; van Eijk, JT, 2002)
"This study was undertaken to compare the efficacy of lansoprazole (LAN)-based triple therapy with that of RBC-based dual therapy in H pylori-infected patients with duodenal ulcer."9.09Lansoprazole-based triple therapy versus ranitidine bismuth citrate-based dual therapy in the eradication of Helicobacter pylori in patients with duodenal ulcer: a multicenter, randomized, double-dummy study. ( Belmonte, A; Cavaliere, C; Ciliberto, E; Fiocca, R; Frandina, C; Giglio, A; Luzza, F; Pallone, F; Saccà, N; Trimboli, V, 2001)
" In this open-label study, the effect of lansoprazole 30 mg qd and naproxen 500 mg bid on the pharmacokinetic profile of methotrexate was investigated."6.71Coadministration of lansoprazole and naproxen does not affect the pharmacokinetic profile of methotrexate in adult patients with rheumatoid arthritis. ( Amer, F; Andhivarothai, N; Kukulka, MJ; Vakily, M, 2005)
"As can be expected, headache was reported less frequently in this study compared with clinical trials with lansoprazole."5.10Determinants of headache in lansoprazole users in The Netherlands: results from a nested case-control study. ( Claessens, AA; Heerdink, ER; Lamers, CB; Leufkens, HG; van Eijk, JT, 2002)
"This study was undertaken to compare the efficacy of lansoprazole (LAN)-based triple therapy with that of RBC-based dual therapy in H pylori-infected patients with duodenal ulcer."5.09Lansoprazole-based triple therapy versus ranitidine bismuth citrate-based dual therapy in the eradication of Helicobacter pylori in patients with duodenal ulcer: a multicenter, randomized, double-dummy study. ( Belmonte, A; Cavaliere, C; Ciliberto, E; Fiocca, R; Frandina, C; Giglio, A; Luzza, F; Pallone, F; Saccà, N; Trimboli, V, 2001)
" The most common adverse events of headache, diarrhea, and nausea have been reported in fewer than 5% of patients treated with lansoprazole or omeprazole."4.80Safety profile of the proton-pump inhibitors. ( Reilly, JP, 1999)
" In this open-label study, the effect of lansoprazole 30 mg qd and naproxen 500 mg bid on the pharmacokinetic profile of methotrexate was investigated."2.71Coadministration of lansoprazole and naproxen does not affect the pharmacokinetic profile of methotrexate in adult patients with rheumatoid arthritis. ( Amer, F; Andhivarothai, N; Kukulka, MJ; Vakily, M, 2005)
"Lansoprazole is a H+."2.68Lansoprazole versus ranitidine for the treatment of reflux oesophagitis. UK Lansoprazole Clinical Research Group. ( Bardhan, KD; Brocklebank, D; Hawkey, CJ; Long, RG; Morgan, AG; Moules, IK; Wormsley, KG, 1995)
"To estimate the rates of common adverse events in patients treated with the proton pump inhibitors omeprazole, lansoprazole and pantoprazole in general practice in England."1.31The rates of common adverse events reported during treatment with proton pump inhibitors used in general practice in England: cohort studies. ( Dunn, NR; Freemantle, S; Martin, RM; Shakir, S, 2000)
"Lansoprazole was mostly prescribed in patients with reflux oesophagitis (55."1.30A prospective follow-up study of 5669 users of lansoprazole in daily practice. ( Claessens, A; Heerdink, E; Lamers, CB; Leufkens, H; van Eijk, J, 1997)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (40.00)18.2507
2000's5 (50.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Woolley, AK1
Hedger, NA1
Veettil, RP1
Kovacs, TO1
Freston, JW1
Haber, MM1
Hunt, B1
Atkinson, S1
Peura, DA1
Vakily, M1
Amer, F1
Kukulka, MJ1
Andhivarothai, N1
Bardhan, KD1
Hawkey, CJ1
Long, RG1
Morgan, AG1
Wormsley, KG1
Moules, IK1
Brocklebank, D1
Sontag, SJ1
Schnell, TG1
Chejfec, G1
Kurucar, C1
Karpf, J1
Levine, G1
Leufkens, H1
Claessens, A1
Heerdink, E1
van Eijk, J1
Lamers, CB2
Reilly, JP1
Martin, RM1
Dunn, NR1
Freemantle, S1
Shakir, S1
Luzza, F1
Giglio, A1
Ciliberto, E1
Belmonte, A1
Cavaliere, C1
Saccà, N1
Frandina, C1
Fiocca, R1
Trimboli, V1
Pallone, F1
Claessens, AA1
Heerdink, ER1
van Eijk, JT1
Leufkens, HG1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Multicenter, Randomized, Double-blinded, Placebo-controlled Pilot Study to Evaluate the Efficacy and Safety of Rebamipide as an Adjuvant Regimen to Heal erosIve Reflux Esophagitis (REPAIR)[NCT02755753]Phase 4143 participants (Actual)Interventional2014-01-31Completed
A Phase I, Randomized, Double-blind, Placebo- and Positive-controlled Study to Evaluate the Safety, Tolerability and Pharmacokinetics/Pharmacodynamics (PK/PD) of Multiple Oral Doses of H008 (Carenoprazan Hydrochloride Tablets) in Healthy Volunteers[NCT05050188]Phase 124 participants (Actual)Interventional2021-06-24Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for lansoprazole and Headache

ArticleYear
Safety profile of the proton-pump inhibitors.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1999, Dec-01, Volume: 56, Issue:23 Suppl 4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Diarrhea; Drug Interactions; Gastric Muc

1999

Trials

6 trials available for lansoprazole and Headache

ArticleYear
Long-term efficacy of lansoprazole in preventing relapse of erosive reflux esophagitis.
    Digestive diseases and sciences, 2009, Volume: 54, Issue:8

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Abdominal Pain; Adult; Aged; Aged, 80 and over; Diarrhea; D

2009
Coadministration of lansoprazole and naproxen does not affect the pharmacokinetic profile of methotrexate in adult patients with rheumatoid arthritis.
    Journal of clinical pharmacology, 2005, Volume: 45, Issue:10

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adult; Aged; Anti-Inflammatory Agents

2005
Lansoprazole versus ranitidine for the treatment of reflux oesophagitis. UK Lansoprazole Clinical Research Group.
    Alimentary pharmacology & therapeutics, 1995, Volume: 9, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Double-Blind Method; Esophagitis, Peptic; Foll

1995
Lansoprazole heals erosive reflux oesophagitis in patients with Barrett's oesophagus.
    Alimentary pharmacology & therapeutics, 1997, Volume: 11, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Barrett Esophagus; Double-Blind Method; Enzyme Inhibitors;

1997
Lansoprazole-based triple therapy versus ranitidine bismuth citrate-based dual therapy in the eradication of Helicobacter pylori in patients with duodenal ulcer: a multicenter, randomized, double-dummy study.
    Clinical therapeutics, 2001, Volume: 23, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Anti-Ulcer Agents; Bismuth; Clarit

2001
Determinants of headache in lansoprazole users in The Netherlands: results from a nested case-control study.
    Drug safety, 2002, Volume: 25, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Age Factors; Aged; Case-Control Studies;

2002

Other Studies

3 other studies available for lansoprazole and Headache

ArticleYear
Problem based review: The patient with a pyrexia of unknown origin.
    Acute medicine, 2013, Volume: 12, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Infective Agents; Anti-Inflammatory Agents; Aorta; Aor

2013
A prospective follow-up study of 5669 users of lansoprazole in daily practice.
    Alimentary pharmacology & therapeutics, 1997, Volume: 11, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agen

1997
The rates of common adverse events reported during treatment with proton pump inhibitors used in general practice in England: cohort studies.
    British journal of clinical pharmacology, 2000, Volume: 50, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Abdominal Pain; Adult; Adverse Drug Reaction Reporting Syst

2000