lansoprazole has been researched along with Gastric Diseases in 17 studies
Lansoprazole: A 2,2,2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS. Lansoprazole is a racemic mixture of (R)- and (S)-isomers.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Side-effect profile and tolerability were assessed using a symptom-based questionnaire." | 2.73 | Efficacy and safety of Saccharomyces boulardii in the 14-day triple anti-Helicobacter pylori therapy: a prospective randomized placebo-controlled double-blind study. ( Cindoruk, M; Dursun, A; Erkan, G; Karakan, T; Unal, S, 2007) |
| " Jatrophone was toxic against both cell lines (IC50 values: 2." | 1.34 | Gastroprotective effect and cytotoxicity of terpenes from the Paraguayan crude drug "yagua rova" (Jatropha isabelli). ( Pertino, M; Rodríguez, JA; Schmeda-Hirschmann, G; Theoduloz, C, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (17.65) | 18.2507 |
| 2000's | 11 (64.71) | 29.6817 |
| 2010's | 3 (17.65) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brown, KB | 1 |
| Bishop, PR | 1 |
| Nowicki, MJ | 1 |
| Liou, JM | 1 |
| Bair, MJ | 1 |
| Chen, CC | 2 |
| Lee, YC | 1 |
| Chen, MJ | 1 |
| Tseng, CH | 1 |
| Fang, YJ | 1 |
| Lee, JY | 1 |
| Yang, TH | 1 |
| Luo, JC | 1 |
| Wu, JY | 1 |
| Chang, WH | 1 |
| Chang, CC | 1 |
| Chen, CY | 1 |
| Chen, PY | 1 |
| Shun, CT | 1 |
| Hsu, WF | 1 |
| Hung, HW | 1 |
| Lin, JT | 1 |
| Chang, CY | 1 |
| Wu, MS | 1 |
| Choi, KE | 1 |
| Kim, MJ | 1 |
| Lee, JH | 2 |
| Lee, JS | 1 |
| Choe, YH | 1 |
| Sullivan, B | 1 |
| Coyle, W | 1 |
| Nemec, R | 1 |
| Dunteman, T | 1 |
| Chuang, CH | 1 |
| Sheu, BS | 1 |
| Huang, AH | 1 |
| Yang, HB | 1 |
| Wu, JJ | 1 |
| Gurbuz, AK | 1 |
| Ozel, AM | 1 |
| Ozturk, R | 1 |
| Yildirim, S | 1 |
| Yazgan, Y | 1 |
| Demirturk, L | 1 |
| Pertino, M | 1 |
| Schmeda-Hirschmann, G | 1 |
| Rodríguez, JA | 1 |
| Theoduloz, C | 1 |
| Kawai, T | 1 |
| Kawakami, K | 1 |
| Mikinori, K | 1 |
| Takei, K | 1 |
| Itoi, T | 1 |
| Moriyasu, F | 1 |
| Takagi, Y | 1 |
| Aoki, T | 1 |
| Watanebe, K | 1 |
| Matsumoto, Y | 1 |
| Rimbara, E | 1 |
| Noguchi, N | 1 |
| Sasatsu, M | 1 |
| Cindoruk, M | 1 |
| Erkan, G | 1 |
| Karakan, T | 1 |
| Dursun, A | 1 |
| Unal, S | 1 |
| Maity, P | 1 |
| Bindu, S | 1 |
| Choubey, V | 1 |
| Alam, A | 1 |
| Mitra, K | 1 |
| Goyal, M | 1 |
| Dey, S | 1 |
| Guha, M | 1 |
| Pal, C | 1 |
| Bandyopadhyay, U | 1 |
| Mégraud, F | 1 |
| Murakami, I | 1 |
| Satoh, H | 1 |
| Asano, S | 1 |
| Maeda, R | 1 |
| Suzuki, H | 1 |
| Mori, M | 1 |
| Sakaguchi, AA | 1 |
| Suzuki, M | 1 |
| Miura, S | 1 |
| Ishii, H | 1 |
| Malki, SA | 1 |
| Yeomans, ND | 1 |
| Bilic, I | 1 |
| Zoricic, I | 1 |
| Anic, T | 1 |
| Separovic, J | 1 |
| Stancic-Rokotov, D | 1 |
| Mikus, D | 1 |
| Buljat, G | 1 |
| Ivankovic, D | 1 |
| Aralica, G | 1 |
| Prkacin, I | 1 |
| Perovic, D | 1 |
| Mise, S | 1 |
| Rotkvic, I | 1 |
| Petek, M | 1 |
| Rucman, R | 1 |
| Seiwerth, S | 1 |
| Sikiric, P | 1 |
| Miehsler, W | 1 |
| Püspök, A | 1 |
| Oberhuber, T | 1 |
| Vogelsang, H | 1 |
| Kazantsev, GB | 1 |
| Schwesinger, WH | 1 |
| Heim-Hall, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison of the Efficacy of Levofloxacin-based Sequential Therapy and Triple Therapy as Second Line Therapy for Refractory Helicobacter Pylori Infection- A Multi-center Randomized Trial[NCT01537055] | Phase 4 | 600 participants (Anticipated) | Interventional | 2012-02-29 | Recruiting | ||
| Personalized Treatment for Refractory H Pylori Infection[NCT02547025] | 126 participants (Actual) | Interventional | 2012-08-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for lansoprazole and Gastric Diseases
| Article | Year |
|---|---|
Adjuvant therapy for Helicobacter pylori eradication: role of lansoprazole shown in vitro.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Cells, Cultured; Chemotherapy, Adjuvant; Duodenal | 1995 |
Is it time to adopt proton pump inhibitors in the prevention of non-steroidal anti-inflammatory drug gastropathy?
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Inflammatory Agents, Non-Steroidal; Benzimidazoles; En | 2000 |
6 trials available for lansoprazole and Gastric Diseases
| Article | Year |
|---|---|
Levofloxacin Sequential Therapy vs Levofloxacin Triple Therapy in the Second-Line Treatment of Helicobacter pylori: A Randomized Trial.
Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Drug Administration Schedule; Drug Monitoring; Drug | 2016 |
Comparison of azithromycin and clarithromycin in triple therapy regimens for the eradication of Helicobacter pylori.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Antacids; Anti-Bacterial Agents; Anti-Ulcer Agents; | 2002 |
Vitamin C and E supplements to lansoprazole-amoxicillin-metronidazole triple therapy may reduce the eradication rate of metronidazole-susceptible Helicobacter pylori infection.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Anti-Bacterial Agents; Ascorbic Acid; D | 2002 |
Effect of N-acetyl cysteine on Helicobacter pylori.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acetylcysteine; Anti-Bacterial Agents; Clarithromycin; Drug | 2005 |
Efficacy of low-dose proton pump inhibitor (PPI) in the eradication of Helicobacter pylori following combination PPI/AC therapy in Japan.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Amoxicillin; Anti-Ulcer Agents; Aryl Hydrocarb | 2007 |
Efficacy and safety of Saccharomyces boulardii in the 14-day triple anti-Helicobacter pylori therapy: a prospective randomized placebo-controlled double-blind study.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Amoxicillin; Clarithromycin; Diarrhea; Double- | 2007 |
9 other studies available for lansoprazole and Gastric Diseases
| Article | Year |
|---|---|
Gastric Polyps—To Worry or Not?
Topics: Adenomatous Polyposis Coli; Adolescent; Humans; Lansoprazole; Male; Peutz-Jeghers Syndrome; Polyps; | 2015 |
Effects of proton pump inhibitors on pediatric inflammatory esophagogastric polyps.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Child; Child, Preschool; Cohort Studies; Endosc | 2012 |
Gastroprotective effect and cytotoxicity of terpenes from the Paraguayan crude drug "yagua rova" (Jatropha isabelli).
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Animals; Anti-Ulcer Agents; Cell Line | 2007 |
Lansoprazole protects and heals gastric mucosa from non-steroidal anti-inflammatory drug (NSAID)-induced gastropathy by inhibiting mitochondrial as well as Fas-mediated death pathways with concurrent induction of mucosal cell renewal.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Inflammatory Agents, Non-Steroidal; Caspases; | 2008 |
Role of capsaicin-sensitive sensory neurons and nitric oxide in the protective effect of lansoprazole, a proton pump inhibitor, on the gastric mucosa in rats.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Capsaicin; Enzyme Inhibitors; Ethanol; Gastric Muc | 1996 |
Enhanced levels of C-X-C chemokine, human GROalpha, in Helicobacter pylori-associated gastric disease.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Bacterial Agents; Anti-Ulcer Agents; Chem | 1998 |
Haloperidol-stomach lesions attenuation by pentadecapeptide BPC 157, omeprazole, bromocriptine, but not atropine, lansoprazole, pantoprazole, ranitidine, cimetidine and misoprostol in mice.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Atropine; Benzimidazoles; Bromo | 2001 |
Impact of different therapeutic regimens on the outcome of patients with Crohn's disease of the upper gastrointestinal tract.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Crohn Disease; Data Interpretatio | 2001 |
Spontaneous resolution of multiple fundic gland polyps after cessation of treatment with lansoprazole and Nissen fundoplication: a case report.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Enzyme Inhibitors; Female; Fundoplication; Gastric Fu | 2002 |