Page last updated: 2024-10-30

lansoprazole and Eosinophilic Esophagitis

lansoprazole has been researched along with Eosinophilic Esophagitis in 3 studies

Lansoprazole: A 2,2,2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS. Lansoprazole is a racemic mixture of (R)- and (S)-isomers.

Eosinophilic Esophagitis: Chronic ESOPHAGITIS characterized by esophageal mucosal EOSINOPHILIA. It is diagnosed when an increase in EOSINOPHILS are present over the entire esophagus. The reflux symptoms fail to respond to PROTON PUMP INHIBITORS treatment, unlike in GASTROESOPHAGEAL REFLUX DISEASE. The symptoms are associated with IgE-mediated hypersensitivity to food or inhalant allergens.

Research Excerpts

ExcerptRelevanceReference
" Proton pump inhibitor (PPI) use in EoE does not lead to histologic improvement; however, the long-term use of PPI on symptoms and prevention of complications has not been evaluated."2.77Conservative long-term treatment of children with eosinophilic esophagitis. ( Edelman, M; Lai, J; Levine, J; Schuval, SJ, 2012)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Koop, AH1
Francis, DL1
Parrish, DW1
Sharma, S1
Kumar, S1
Levine, J1
Lai, J1
Edelman, M1
Schuval, SJ1

Trials

1 trial available for lansoprazole and Eosinophilic Esophagitis

ArticleYear
Conservative long-term treatment of children with eosinophilic esophagitis.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2012, Volume: 108, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Child; Child, Preschool; Deglutition Disorders; Endoscopy;

2012

Other Studies

2 other studies available for lansoprazole and Eosinophilic Esophagitis

ArticleYear
A Rare Case of Eosinophilic Esophagitis and Dysphagia Lusoria.
    The American journal of gastroenterology, 2020, Volume: 115, Issue:7

    Topics: Adult; Computed Tomography Angiography; Deglutition Disorders; Endoscopy, Digestive System; Eosinoph

2020
Is the consistency more important than the ingredients for steroid treatment in eosinophilic esophagitis?
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2014, Volume: 112, Issue:4

    Topics: Budesonide; Child, Preschool; Combined Modality Therapy; Diet Therapy; Eosinophilic Esophagitis; Eos

2014