lansoprazole has been researched along with Eosinophilia in 10 studies
Lansoprazole: A 2,2,2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS. Lansoprazole is a racemic mixture of (R)- and (S)-isomers.
Eosinophilia: Abnormal increase of EOSINOPHILS in the blood, tissues or organs.
| Excerpt | Relevance | Reference |
|---|---|---|
| "It was shown that gastroesophageal reflux disease was one of the possible causes of eosinophilia." | 1.34 | [A case of gastroesophageal reflux disease with marked eosinophilia]. ( Inoue, T; Inui, Y; Katata, T; Kizu, T; Kohro, T; Matsumoto, Y; Miyoshi, R; Nishikawa, M; Watanabe, C; Yasunaga, Y, 2007) |
| "In refractory cases of GERD, eosinophilic esophagitis must be considered before any surgical measure." | 1.32 | Eosinophilic infiltration of the esophagus: gastroesophageal reflux versus eosinophilic esophagitis in children--discussion on daily practice. ( Cury, EK; Faintuch, S; Schraibman, V, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 6 (60.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Páramo-Zunzunegui, J | 1 |
| Ortega-Fernandez, I | 1 |
| Benito-Barbero, S | 1 |
| Rubio-López, L | 1 |
| Pierog, AA | 1 |
| Mencin, AA | 1 |
| González F, CG | 1 |
| Torres, J | 1 |
| Molina U, R | 1 |
| Harris, PR | 1 |
| Dohil, R | 1 |
| Newbury, R | 1 |
| Fox, L | 1 |
| Bastian, J | 1 |
| Aceves, S | 1 |
| Abraham, D | 1 |
| Saltoun, CA | 1 |
| Cury, EK | 1 |
| Schraibman, V | 1 |
| Faintuch, S | 1 |
| Tiesmeier, J | 1 |
| Hinner, H | 1 |
| Kraus, J | 1 |
| Schuppert, F | 1 |
| Magalhães, AF | 1 |
| Carvalhaes, A | 1 |
| Natan-Eisig, J | 1 |
| Paraíso-Ferraz, JG | 1 |
| Trevisan, M | 1 |
| Zaterkaad, S | 1 |
| Miyoshi, R | 1 |
| Yasunaga, Y | 1 |
| Kizu, T | 1 |
| Inoue, T | 1 |
| Watanabe, C | 1 |
| Matsumoto, Y | 1 |
| Katata, T | 1 |
| Inui, Y | 1 |
| Kohro, T | 1 |
| Nishikawa, M | 1 |
| Takeda, K | 1 |
| Nakamoto, M | 1 |
| Nishihara, G | 1 |
| Ueno, K | 1 |
| Yasunaga, C | 1 |
| Matsuo, K | 1 |
| Urabe, M | 1 |
| Goya, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized Controlled Trial Comparing Fluticasone Plus Omeprazole With Fluticasone Alone for Eosinophilic Esophagitis[NCT03781596] | Phase 4 | 100 participants (Anticipated) | Interventional | 2018-10-02 | Recruiting | ||
| Use of Topical Budesonide in the Treatment of Eosinophilic Esophagitis, a Randomized Clinical Trial[NCT00638456] | Phase 2 | 32 participants (Actual) | Interventional | 2008-02-29 | Completed | ||
| Prospective Pilot Study Evaluating the Efficacy of Low-Dose Topical Steroids in Maintaining Histologic Remission of Eosinophilic Esophagitis in Children[NCT05309590] | 50 participants (Anticipated) | Observational [Patient Registry] | 2014-05-31 | Active, not recruiting | |||
| Phenotypic Characterization of Pediatric Patients With Esophageal Eosinophilia and Biomarkers Investigation for the Diagnosis of Eosinophilic Esophagitis[NCT03069573] | 110 participants (Actual) | Observational [Patient Registry] | 2015-01-01 | Completed | |||
| A Trial of Montelukast for Maintenance Therapy of Eosinophilic Esophagitis in Children[NCT01458418] | 4 participants (Actual) | Interventional | 2011-12-31 | Terminated (stopped due to Inability to complete enrollment due to difficulty in finding subjects) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Repeat endoscopy was undertaken using the Olympus P160 endoscope (by RD) at 3 months of treatment. (NCT00638456)
Timeframe: 3 Months
| Intervention | Participants (Count of Participants) |
|---|---|
| Oral Viscous Budesonide Plus Prevacid | 13 |
| Placebo Plus Prevacid | 0 |
"Total score was based on the following symptoms:~Heartburn/regurgitation Abdominal pain Nausea/vomiting Anorexia/early satiety Dysphagia Symptom induced nocturnal wakening Gastrointestinal bleeding~Each symptom could score 0-2 for a maximum score for 14 points. The lower the score the milder the symptoms and the higher the score the more severe symptoms." (NCT00638456)
Timeframe: Baseline and 3 Months
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Baseline | 3 months | |
| Oral Viscous Budesonide Plus Prevacid | 3.5 | 1.2 |
| Placebo Plus Prevacid | 2.7 | 1.8 |
"Endoscopy scoring tool took into account the following categories:~Mucosal pallor/reduced vasculature Linear furrows/mucosal thickening White plaques Concentric rings/stricture Friability/tissue-paper mucosa Histology scoring tools Epithelial histology score Peak eosinophil count~Each category could score 0-3 for a total maximum score of 15. The higher the score the worse the disease." (NCT00638456)
Timeframe: Baseline and 3 Months
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Baseline | 3 months | |
| Oral Viscous Budesonide Plus Prevacid | 4.6 | 1.5 |
| Placebo Plus Prevacid | 7.8 | 5.4 |
Eosinophils/high powered field(hpf) in the mid esophagus will be measured after 12 weeks of therapy. (NCT01458418)
Timeframe: 12 weeks
| Intervention | Eosinophils/HPF (Mean) |
|---|---|
| Subjects Whose Arm is Unknown Due to Not Being Unblinded | 8 |
1 trial available for lansoprazole and Eosinophilia
| Article | Year |
|---|---|
Oral viscous budesonide is effective in children with eosinophilic esophagitis in a randomized, placebo-controlled trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adolescent; Anti-Inflammatory Agents; | 2010 |
Oral viscous budesonide is effective in children with eosinophilic esophagitis in a randomized, placebo-controlled trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adolescent; Anti-Inflammatory Agents; | 2010 |
Oral viscous budesonide is effective in children with eosinophilic esophagitis in a randomized, placebo-controlled trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adolescent; Anti-Inflammatory Agents; | 2010 |
Oral viscous budesonide is effective in children with eosinophilic esophagitis in a randomized, placebo-controlled trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adolescent; Anti-Inflammatory Agents; | 2010 |
Oral viscous budesonide is effective in children with eosinophilic esophagitis in a randomized, placebo-controlled trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adolescent; Anti-Inflammatory Agents; | 2010 |
Oral viscous budesonide is effective in children with eosinophilic esophagitis in a randomized, placebo-controlled trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adolescent; Anti-Inflammatory Agents; | 2010 |
Oral viscous budesonide is effective in children with eosinophilic esophagitis in a randomized, placebo-controlled trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adolescent; Anti-Inflammatory Agents; | 2010 |
Oral viscous budesonide is effective in children with eosinophilic esophagitis in a randomized, placebo-controlled trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adolescent; Anti-Inflammatory Agents; | 2010 |
Oral viscous budesonide is effective in children with eosinophilic esophagitis in a randomized, placebo-controlled trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adolescent; Anti-Inflammatory Agents; | 2010 |
Oral viscous budesonide is effective in children with eosinophilic esophagitis in a randomized, placebo-controlled trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adolescent; Anti-Inflammatory Agents; | 2010 |
Oral viscous budesonide is effective in children with eosinophilic esophagitis in a randomized, placebo-controlled trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adolescent; Anti-Inflammatory Agents; | 2010 |
Oral viscous budesonide is effective in children with eosinophilic esophagitis in a randomized, placebo-controlled trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adolescent; Anti-Inflammatory Agents; | 2010 |
Oral viscous budesonide is effective in children with eosinophilic esophagitis in a randomized, placebo-controlled trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adolescent; Anti-Inflammatory Agents; | 2010 |
Oral viscous budesonide is effective in children with eosinophilic esophagitis in a randomized, placebo-controlled trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adolescent; Anti-Inflammatory Agents; | 2010 |
Oral viscous budesonide is effective in children with eosinophilic esophagitis in a randomized, placebo-controlled trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adolescent; Anti-Inflammatory Agents; | 2010 |
Oral viscous budesonide is effective in children with eosinophilic esophagitis in a randomized, placebo-controlled trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adolescent; Anti-Inflammatory Agents; | 2010 |
Oral viscous budesonide is effective in children with eosinophilic esophagitis in a randomized, placebo-controlled trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adolescent; Anti-Inflammatory Agents; | 2010 |
Oral viscous budesonide is effective in children with eosinophilic esophagitis in a randomized, placebo-controlled trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adolescent; Anti-Inflammatory Agents; | 2010 |
Oral viscous budesonide is effective in children with eosinophilic esophagitis in a randomized, placebo-controlled trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adolescent; Anti-Inflammatory Agents; | 2010 |
Oral viscous budesonide is effective in children with eosinophilic esophagitis in a randomized, placebo-controlled trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adolescent; Anti-Inflammatory Agents; | 2010 |
Oral viscous budesonide is effective in children with eosinophilic esophagitis in a randomized, placebo-controlled trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adolescent; Anti-Inflammatory Agents; | 2010 |
Oral viscous budesonide is effective in children with eosinophilic esophagitis in a randomized, placebo-controlled trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adolescent; Anti-Inflammatory Agents; | 2010 |
Oral viscous budesonide is effective in children with eosinophilic esophagitis in a randomized, placebo-controlled trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adolescent; Anti-Inflammatory Agents; | 2010 |
Oral viscous budesonide is effective in children with eosinophilic esophagitis in a randomized, placebo-controlled trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adolescent; Anti-Inflammatory Agents; | 2010 |
Oral viscous budesonide is effective in children with eosinophilic esophagitis in a randomized, placebo-controlled trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adolescent; Anti-Inflammatory Agents; | 2010 |
9 other studies available for lansoprazole and Eosinophilia
| Article | Year |
|---|---|
Eosinophilic colitis: an infrequent disease with difficult diagnose.
Topics: Aged, 80 and over; Biopsy; Colitis; Colon; Colonoscopy; Cromolyn Sodium; Drug Therapy, Combination; | 2020 |
A childhood case of eosinophilic gastritis and protein-losing enteropathy.
Topics: Anti-Asthmatic Agents; Anti-Inflammatory Agents; Anti-Ulcer Agents; Asthma; Child, Preschool; Cromol | 2014 |
[Eosinophilic esophagitis: report of three cases].
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acetates; Adolescent; Child; Cyclopropanes; Eosinophilia; E | 2009 |
Facial swelling and eosinophilia in a 44-year-old woman.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Angioedema; Cefuroxime; Cetirizine; Diagnosis, Diffe | 2002 |
Eosinophilic infiltration of the esophagus: gastroesophageal reflux versus eosinophilic esophagitis in children--discussion on daily practice.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Biopsy; Child; Cimetidine; Diagnosis, Differential; Enzyme | 2004 |
[Chronic upper abdominal pain without improvement after using proton pump inhibitors].
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Abdominal Pain; Anti-Ulcer Agents; Azathioprine; Duodenal U | 2004 |
CagA status and Helicobacter pylori eradication among dyspeptic patients.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Amoxicillin; Anti-Bacterial Agents | 2005 |
[A case of gastroesophageal reflux disease with marked eosinophilia].
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Eosinophilia; Esophagitis, Peptic; Female; Gastroesop | 2007 |
Severe eosinophilia related with lansoprazole in a hemodialysis patient.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Anti-Ulcer Agents; Blood Chemical Analysis; Cel | 1998 |