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lansoprazole and Duodenal Ulcer

lansoprazole has been researched along with Duodenal Ulcer in 150 studies

Lansoprazole: A 2,2,2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS. Lansoprazole is a racemic mixture of (R)- and (S)-isomers.

Duodenal Ulcer: A PEPTIC ULCER located in the DUODENUM.

Research Excerpts

ExcerptRelevanceReference
"Clinical experience with lansoprazole in the acute treatment of duodenal ulcer patients has been compared with treatment using placebo, H2-antagonists or omeprazole."10.17Acute treatment of duodenal ulcer: experience with lansoprazole. ( Mignon, M; Vallot, T, 1993)
" This study aimed to establish the noninferiority of keverprazan to lansoprazole in the treatment of patients with duodenal ulcer (DU)."9.69Efficacy and Safety of Keverprazan Compared With Lansoprazole in the Treatment of Duodenal Ulcer: A Phase III, Randomized, Double-Blind, Multicenter Trial. ( Chen, HH; Chen, HX; Chen, MH; Guo, QH; Li, FF; Li, SB; Li, X; Liao, AJ; Liu, CX; Liu, XW; Liu, YL; Miao, XP; Tan, ND; Tang, YP; Wu, H; Xia, M; Xiao, YL; Zhang, Y; Zhang, ZY, 2023)
"In this phase 3, randomized (1:1), double-blind, double-dummy, parallel-group, non-inferiority study (April 5, 2017, to July 19, 2019), patients with ≥ 1 endoscopically confirmed duodenal ulcer, at 52 hospitals (China, South Korea, and Taiwan), received vonoprazan 20 mg once daily (QD) or lansoprazole 30 mg QD for 6 weeks maximum."9.51Vonoprazan non-inferior to lansoprazole in treating duodenal ulcer and eradicating Helicobacter pylori in Asian patients. ( Chiu, CT; Chong, CF; Chung, WC; Gu, L; Hou, X; Kudou, K; Meng, F; Sha, W; Wang, J; Zhang, S, 2022)
" lansoprazole, a proton pump inhibitor, for treatment of gastric ulcer (GU) or duodenal ulcer (DU)."9.24Randomised clinical trial: efficacy and safety of vonoprazan vs. lansoprazole in patients with gastric or duodenal ulcers - results from two phase 3, non-inferiority randomised controlled trials. ( Miwa, H; Mori, Y; Nishimura, A; Sakaki, N; Sakurai, Y; Takanami, Y; Tatsumi, T; Uedo, N; Watari, J, 2017)
"Low-dose lansoprazole has not been intensively evaluated for its efficacy in the prevention of recurrent gastric or duodenal ulcers in patients receiving long-term non-steroidal anti-inflammatory drug (NSAID) therapy for pain relief in such diseases as rheumatoid arthritis, osteoarthritis, and low back pain."9.16Lansoprazole for secondary prevention of gastric or duodenal ulcers associated with long-term non-steroidal anti-inflammatory drug (NSAID) therapy: results of a prospective, multicenter, double-blind, randomized, double-dummy, active-controlled trial. ( Asaka, M; Ashida, K; Hiraishi, H; Hiramatsu, N; Kanto, T; Katsuo, S; Kontani, T; Matsui, S; Mizokami, Y; Sakaki, N; Soen, S; Sugano, K; Takei, Y; Takeuchi, T, 2012)
"The efficacy of low-dose lansoprazole has not been established for the prevention of recurrent gastric or duodenal ulcers in those receiving long-term low-dose aspirin (LDA) for cardiovascular and cerebrovascular protection."9.15Lansoprazole for secondary prevention of gastric or duodenal ulcers associated with long-term low-dose aspirin therapy: results of a prospective, multicenter, double-blind, randomized, double-dummy, active-controlled trial. ( Abe, S; Ashida, K; Chiba, T; Hiramatsu, N; Itabashi, T; Kanto, T; Matsui, S; Matsumoto, Y; Mizokami, Y; Sakaki, N; Shimada, K; Sugano, K; Uchiyama, S; Uemura, N, 2011)
"Sixty-seven patients (49 with Zollinger-Ellison syndrome [ZES], 18 without), with basal acid output (BAO) >15 mmol/h or >5 mmol/h if post-antrectomy (n = 9, all ZES), were treated with individually optimized doses of lansoprazole (7."9.11Clinical outcome using lansoprazole in acid hypersecretors with and without Zollinger-Ellison syndrome: a 13-year prospective study. ( Hirschowitz, BI; Mohnen, J; Simmons, J, 2005)
"To compare lansoprazole 30 mg once daily, lansoprazole 15 mg once daily and ranitidine 150 mg once nightly in the prevention of duodenal ulcer relapse in patients whose duodenal ulcers had been previously healed with lansoprazole 30 mg once daily or ranitidine 300 mg nightly."9.09Lansoprazole is superior to ranitidine as maintenance treatment for the prevention of duodenal ulcer relapse. ( Bardhan, KD; Crouch, SL; Crowe, J; Keeling, PN; Thompson, RP; Trewby, PN; Weir, D, 1999)
"Lansoprazole safely and effectively reduces duodenal ulcer recurrence and ulcer-related symptoms."9.09Double-blind comparison of lansoprazole 15 mg, lansoprazole 30 mg and placebo as maintenance therapy in patients with healed duodenal ulcers resistant to H2-receptor antagonists. ( Campbell, D; Haber, M; Jennings, DE; Kovacs, TO; Richter, J; Rose, P, 1999)
"The aim of this randomized, multicenter, double-masked, parallel-group study was to compare the efficacy of lansoprazole with that of omeprazole monotherapy in duodenal ulcer healing and prevention of relapse."9.09Lansoprazole versus omeprazole for duodenal ulcer healing and prevention of relapse: a randomized, multicenter, double-masked trial. ( Dobrilla, G; Fiocca, R; Piazzi, L, 1999)
"To compare two lansoprazole-based non-clarithromycin triple therapies and one dual therapy in a prospective double-blind placebo-controlled study of Helicobacter pylori eradication and duodenal ulcer healing."9.09Comparison of lansoprazole-based triple and dual therapy for treatment of Helicobacter pylori-related duodenal ulcer: an Asian multicentre double-blind randomized placebo controlled study. ( Carpio, RE; Fock, KM; Ho, J; Hu, FL; Hu, PJ; Huang, NX; Kachintorn, U; Kullavanijaya, P; Lam, SK; Lesmana, L; Li, YY; Manan, C; Perez, JY; Phornphutkul, K; Qian, SC; Wong, BC; Xiao, SD, 2000)
"The primary objective of the present study was to evaluate the efficacy of 30 and 60 mg of lansoprazole administered in combination with two antibiotics for 7 or 10 days in eradicating Helicobacter pylori in duodenal ulcer patients."9.09[Treatment of Helicobacter pylori infection with lansoprazole 30 mg or 60 mg combined with two antibiotics for duodenal ulcers]. ( Joubert-Collin, M; Lamouliatte, H; Perie, F, 2000)
"The aim of this study was to compare in an open, controlled and prospective trial the efficacy of one-week regimen using either lansoprazole (2 x 30 mg) + 2 x 500 mg metronidazole + 2 x 250 mg clarithromycin (group I, 60 cases) or ranitidine bismuth citrate (2 x 400 mg) + 2 x 500 mg metronidazole + 2 x 250 mg clarithromycin (group II, 61 cases) on the eradication of Hp infection in duodenal ulcer patients."9.09[Lansoprazole versus ranitidine bismuth citrate containing triple regimens for Helicobacter pylori eradication in patients with duodenal ulcer]. ( Buzás György, M; Illyés, G; Székely, E; Széles, I, 2000)
" Fifty patients with active or scarred duodenal ulcer were randomized to lansoprazole or omeprazole for 1 to 4 weeks, with clarithromycin 250 mg twice a day and tinidazole 500 mg twice a day for the first week."9.09Long-term follow-up and serologic assessment after triple therapy with omeprazole or lansoprazole of Helicobacter-associated duodenal ulcer. ( Fanti, L; Guslandi, M; Ieri, R; Mezzi, G; Passaretti, S; Testoni, PA, 2001)
" pylori-positive duodenal ulcers were randomized to receive either lansoprazole 30 mg, clarithromycin 500 mg, and metronidazole 400 mg twice daily for 7 days (LCM-7) or lansoprazole 30 mg, clarithromycin 500 mg, metronidazole 400 mg, and bismuth subcitrate 240 mg twice daily for 3 days (LCMB-3)."9.09Three-day lansoprazole quadruple therapy for Helicobacter pylori-positive duodenal ulcers: a randomized controlled study. ( Chan, CK; Chu, KM; Fung, FM; Hu, FL; Hu, WH; Hui, WM; Kung, NN; Lai, KC; Lam, SK; Lau, GK; Liu, XG; Wang, WH; Wong, BC; Wong, WM; Yuen, MF, 2001)
"This study was undertaken to compare the efficacy of lansoprazole (LAN)-based triple therapy with that of RBC-based dual therapy in H pylori-infected patients with duodenal ulcer."9.09Lansoprazole-based triple therapy versus ranitidine bismuth citrate-based dual therapy in the eradication of Helicobacter pylori in patients with duodenal ulcer: a multicenter, randomized, double-dummy study. ( Belmonte, A; Cavaliere, C; Ciliberto, E; Fiocca, R; Frandina, C; Giglio, A; Luzza, F; Pallone, F; Saccà, N; Trimboli, V, 2001)
" pylori positive duodenal ulcer were enrolled and randomly allocated into one of the five treatment groups: 1) group A: received lansoprazole 30 mg once daily for 2 weeks plus amoxicillin (AM) 500 mg and metronidazole (MZ) 500 mg twice daily for one week in the first week; 2) group B: the AM in group A was replaced by clarithromycin (CM) 250 mg; 3) group C: the MZ in group A was replaced by CM 250 mg; 4) group D: the AM and CM in group C was used for 2 wk; 5) group E: the CM in group D was doubled to 500 mg twice daily."9.09A multicenter study on eradication of Helicobacter pylori infection in patients with duodenal ulcer by lansoprazole-antibiotics combined therapy. ( Hsu, CT; Kuo, CF; Wang, CS; Wang, TH; Yang, JC; Yang, KC, 1999)
"Satisfactory antral biopsies were obtained from 119 duodenal ulcer patients before and after 4 wk of therapy with lansoprazole, ranitidine, or placebo."9.08The effects of short-term lansoprazole therapy on Helicobacter pylori infection and antral gastritis in duodenal ulcer patients. ( Atkinson, BF; Brightman, SA; Jhala, NC; McFarland, MM; Morale, B; Rubin, W, 1995)
"This study reports preliminary results of a controlled, multicenter trial on the quality of ulcer healing induced by lansoprazole (LPZ) or roxatidine (R) in gastric ulcer (GU) or duodenal ulcer (DU) patients."9.08Quality of peptic ulcer healing induced by lansoprazole and roxatidine. ( Fujino, MA; Kobayashi, K; Morozumi, A; Ohtsuka, H; Sano, S; Suzuki, Y; Tachikawa, H; Uchida, N; Ueda, F; Yamamoto, Y, 1995)
"The clinical usefulness of lansoprazole in the healing of gastric and duodenal ulcers, the S2-stage shift rate (white scarring rate), and endoscopic healing rate with respect to degree of gastric mucosal atrophy were investigated."9.08Clinical evaluation of lansoprazole in the treatment of peptic ulcers: initial healing and prevention of relapse. Tohoku Peptic Ulcer Study Group. ( Asaki, S; Hongo, M; Sakurada, H; Sato, A; Takeda, T; Toyota, T, 1995)
"In the present study, the effects of short-term treatment with lansoprazole on healing and recurrence of peptic ulcer were investigated."9.08The effect of lansoprazole treatment on the healing and relapse of peptic ulcer and serum levels of IgG anti-Helicobacter pylori antibody. ( Akimoto, K; Fukujin, H; Katoaka, A; Mashima, H; Mine, T; Nagasawa, J; Tajima, A; Takano, T; Tsuchida, T; Yasuda, H, 1995)
"In this double-blind randomized comparative study patients with active duodenal ulcers were treated with either 30 mg lansoprazole or 20 mg omeprazole in the morning."9.08Lansoprazole versus omeprazole in active duodenal ulcer. A double-blind, randomized, comparative study. ( Anker-Hansen, O; Carling, L; Ekström, P; Sellström, H; Sjöstedt, S; Unge, P, 1995)
"A double-blind, multicentre study was undertaken in 296 patients with endoscopically proven duodenal ulcer to compare the efficacy and safety of lansoprazole 15, 30 or 60 mg with placebo."9.08A comparison of three doses of lansoprazole (15, 30 and 60 mg) and placebo in the treatment of duodenal ulcer. The Lansoprazole Study Group. ( Avner, DL; Dorsch, ER; Greski-Rose, PA; Jennings, DE, 1995)
"To evaluate the efficacy of a second generation acid pump inhibitor-lansoprazole (L) a controlled clinical trial in 72 patients of duodenal ulcer was carried out with omeprazole (O) as control."9.08[A clinical trial of lansoprazole in the treatment of duodenal ulcer]. ( Chen, S; Pei, Y; Wang, B, 1995)
" pylori-positive duodenal ulcer were randomly assigned to receive one of the following three antiulcer regimens: (1) lansoprazole 30 mg b."9.08Comparison of two lansoprazole-antibiotic combinations (amoxycillin or classical triple therapy) for treatment of H. pylori infection in duodenal ulcer patients. ( Bargiggia, S; Bianchi Porro, G; Colombo, E; Maconi, G; Parente, F, 1996)
"We report long-term, up to 4 years, prospective treatment using lansoprazole in nine male patients with duodenal ulcers and a BAO of more than 15 mmol/h whose results are compared with those in 10 male Zollinger-Ellison syndrome patients with intact stomachs reported in detail in an accompanying paper."9.08Long-term treatment with lansoprazole of patients with duodenal ulcer and basal acid output of more than 15 mmol/h. ( Hirschowitz, BI; Mohnen, J; Shaw, S, 1996)
"Eighty patients with endoscopically proven active duodenal ulcer were randomized to take ranitidine or lansoprazole for 4-8 wk, together with clarithromycin 250 mg b."9.08Triple therapy with ranitidine or lansoprazole in the treatment of Helicobacter pylori-associated duodenal ulcer. ( Bargiggia, S; Bianchi Porro, G; Lazzaroni, M, 1997)
" The aim of the present study was to assess efficacy and tolerability of the proton pump inhibitors lansoprazole given at bedtime as compared to ranitidine, both in acute and maintenance treatment of duodenal ulcer."9.08Bedtime administration of lansoprazole does not modify its greater efficacy vs ranitidine in the acute and long-term treatment of duodenal ulcer. Results from a multicentre, randomised, double blind clinical trial. ( Dattilo, M; Russo, A, 1997)
" Fasting had no influence on the result of duodenal ulcer treatment by lansoprazole which was well tolerated."9.08[Effect of the observance of diurnal fast of Ramadan on duodenal ulcer healing with lansoprazole. Results of a prospective controlled study]. ( Ajmi, S; Mehdi, A, 1997)
" pylori-infected duodenal ulcer patients we investigated the gastritis parameters in antral and corpus mucosa before treatment, after 6 and 12 months of therapy, and 6 months after termination of treatment with 15 mg lansoprazole or 150 mg ranitidine/day."9.08Changes in Helicobacter pylori-induced gastritis in the antrum and corpus during and after 12 months of treatment with ranitidine and lansoprazole in patients with duodenal ulcer disease. ( Kiel, G; Meining, A; Stolte, M, 1998)
"To study in a double-blind controlled manner the effects of lansoprazole 15 mg or 30 mg daily compared with ranitidine 300 mg once daily and placebo in the relieving of symptoms and healing of acute duodenal ulceration."9.07Double-blind comparison of lansoprazole, ranitidine, and placebo in the treatment of acute duodenal ulcer. Lansoprazole Study Group. ( Goff, J; Greski-Rose, P; Jennings, D; Lanza, F; Scowcroft, C, 1994)
"The purpose of this study was to compare duodenal ulcer healing, symptom relief, and safety of lansoprazole (a new proton pump inhibitor) given at doses of 30 mg and 60 mg, in the morning with ranitidine 300 mg at bedtime."9.07Improved symptom relief and duodenal ulcer healing with lansoprazole, a new proton pump inhibitor, compared with ranitidine. ( Bardhan, KD; Christian, J; Cochran, KM; Hawkey, CJ; Long, RG; Moules, IK; Wormsley, KG, 1993)
"The efficacy of lansoprazole (30 mg/d) and omeprazole (20 mg/d) has been assessed in active duodenal ulcer disease in 144 patients included in a multicentric, randomized, double-blind trial."9.07[Comparison of lansoprazole (30 mg) and omeprazole (20 mg) in the treatment of duodenal ulcer. A multicenter double-blind comparative trial]. ( Andrieu, J; Coste, T; Dupuis, J; Grimaud, JC; Julien, H; Lemerez, M; Licht, H; Petite, JP; Sallerin, V; Slama, JL, 1993)
"Forty-two patients with peptic ulceration of the duodenum, stomach or oesophagus, who had not responded to 3 or more months of high-dose treatment with ranitidine (450 or 600 mg/day), were treated with oral lansoprazole at 30-60 mg daily."9.07An open trial of long-term therapy with lansoprazole in patients with peptic ulceration resistant to extended high-dose ranitidine treatment. ( Arnold, R; Brunner, G; Fuchs, W; Hennig, U, 1993)
" In this 2:1 randomized, double-blind, multicentre trial lansoprazole 30 mg am was compared to 40 mg famotidine nocte in 264 out-patients suffering from uncomplicated duodenal ulcer."9.07Lansoprazole versus famotidine: efficacy and tolerance in the acute management of duodenal ulceration. ( Grymbowski, T; Hennig, U; Hotz, J; Kleinert, R; Schwarz, JA, 1992)
" This randomized, double-blind multicentre trial studied the dose-response relationship of lansoprazole on ulcer healing and compared it with ranitidine in 314 out-patients with endoscopically assessed, symptomatic duodenal ulcer."9.07Dose-related healing of duodenal ulcer with the proton pump inhibitor lansoprazole. ( Barth, H; Dammann, HG; Hengels, KJ; Kleinert, R; Londong, W; Müller, P; Rohde, H; Simon, B, 1991)
"The aim was to compare the clinical efficacy of lansoprazole with the efficacies of ranitidine and famotidine in order to rank this drug in the hierarchy of duodenal ulcer treatments."8.79Meta-analysis of randomized clinical trials comparing lansoprazole with ranitidine or famotidine in the treatment of acute duodenal ulcer. ( Agostini, H; Lemaire, M; Poynard, T, 1995)
" Cysteamine inhibits the release of somatostatin and induces the formation of duodenal ulcers in rats."7.73Enhanced ghrelin secretion in rats with cysteamine-induced duodenal ulcers. ( Arakawa, M; Fukuhara, S; Hibi, T; Hosoda, H; Ishii, H; Kangawa, K; Kitajima, M; Masaoka, T; Minegishi, Y; Suzuki, H, 2005)
" Likewise, pantoprazole showed the healing promoting action on chronic duodenal ulcers induced by acetic acid, and this effect was also more potent when compared to omeprazole or lansoprazole."7.70Effects of pantoprazole, a novel H+/K+-ATPase inhibitor, on duodenal ulcerogenic and healing responses in rats: a comparative study with omeprazole and lansoprazole. ( Kato, S; Konaka, A; Nishijima, M; Takeuchi, K; Yasuhiro, T, 1999)
"One-week therapy with lansoprazole, amoxicillin and clarithromycin is highly effective in duodenal ulcer healing and symptom improvement."7.69Duodenal ulcer healing after 7-day treatment: a pilot study with lansoprazole, amoxicillin and clarithromycin. ( Hentschel, E; Schütze, K, 1995)
"To study the efficiency of the combination lansoprazole and amoxicillin on the eradication of Helicobacter pylori and duodenal ulcer healing."7.69[Erradicating treatment of Helicobacter pylori with lansoprazole and amoxicillin in duodenal ulcer patients]. ( Aller, R; Alvarez Baleriola, I; Bermejo, F; Boixeda, D; Gisbert, JP; Martín de Argila, C, 1996)
" The optimal dosage and duration of treatment need to be specified."6.68Lansoprazole versus lansoprazole plus amoxicillin treatment for eradication of Helicobacter pylori in patients with gastric ulcer. ( Fujita, N; Hisano, K; Kobayashi, T; Kurokawa, I; Ochiai, T; Sugiyama, T; Yabana, T; Yachi, A, 1995)
"Lansoprazole 30 mg/day was administered to 124 gastric ulcer (GU) patients and 57 duodenal ulcer (DU) patients."6.68Peptic ulcer therapy with lansoprazole and Helicobacter pylori eradication. ( Kato, T; Ogoshi, K; Sakagawa, T, 1995)
"When lansoprazole alone was administered to the patients, H."6.68[Effect of treatment with lansoprazole and amoxicillin in combination on healing process of duodenal ulcer]. ( Maruyama, M, 1996)
"Time to ulcer recurrence was significantly longer (P < 0."6.68Prevention of duodenal ulcer recurrence with 15 mg lansoprazole: a double-blind placebo-controlled study. The Lansoprazole Study Group. ( Goff, J; Greski-Rose, P; Jennings, D; Jhala, N; Lanza, F; Silvers, D; Winters, J, 1997)
"Clinical experience with lansoprazole in the acute treatment of duodenal ulcer patients has been compared with treatment using placebo, H2-antagonists or omeprazole."6.17Acute treatment of duodenal ulcer: experience with lansoprazole. ( Mignon, M; Vallot, T, 1993)
" This study aimed to establish the noninferiority of keverprazan to lansoprazole in the treatment of patients with duodenal ulcer (DU)."5.69Efficacy and Safety of Keverprazan Compared With Lansoprazole in the Treatment of Duodenal Ulcer: A Phase III, Randomized, Double-Blind, Multicenter Trial. ( Chen, HH; Chen, HX; Chen, MH; Guo, QH; Li, FF; Li, SB; Li, X; Liao, AJ; Liu, CX; Liu, XW; Liu, YL; Miao, XP; Tan, ND; Tang, YP; Wu, H; Xia, M; Xiao, YL; Zhang, Y; Zhang, ZY, 2023)
"In this phase 3, randomized (1:1), double-blind, double-dummy, parallel-group, non-inferiority study (April 5, 2017, to July 19, 2019), patients with ≥ 1 endoscopically confirmed duodenal ulcer, at 52 hospitals (China, South Korea, and Taiwan), received vonoprazan 20 mg once daily (QD) or lansoprazole 30 mg QD for 6 weeks maximum."5.51Vonoprazan non-inferior to lansoprazole in treating duodenal ulcer and eradicating Helicobacter pylori in Asian patients. ( Chiu, CT; Chong, CF; Chung, WC; Gu, L; Hou, X; Kudou, K; Meng, F; Sha, W; Wang, J; Zhang, S, 2022)
"Considering the limitation of varying acid suppression of proton pump inhibitors, this study was aimed to assess the efficacy, safety, and dose-effect relationship of keverprazan, a novel potassium-competitive acid blocker, in the treatment of duodenal ulcer (DU) compared with lansoprazole."5.51Efficacy of keverprazan for duodenal ulcer: A phase II randomized, double-blind, parallel-controlled trial. ( Chen, HH; Chen, MH; Deng, H; Du, SY; Huo, LJ; Li, SB; Li, X; Liao, AJ; Liu, CX; Liu, HL; Liu, XW; Peng, Q; Qi, LZ; Shen, PZ; Shi, RH; Shu, X; Tan, ND; Tuo, BG; Wang, BM; Wang, JN; Wang, QZ; Wu, H; Xiao, YL; Ye, B; Zhan, Q; Zhang, BQ; Zhang, GX; Zhang, ZY; Zhen, YB, 2022)
" Recurrent upper GI bleeding occurred in one patient receiving lansoprazole (duodenal ulcer) and three receiving famotidine (two gastric ulcers and one duodenal ulcer)."5.34Prevention of recurrent idiopathic gastroduodenal ulcer bleeding: a double-blind, randomised trial. ( Chan, FKL; Ching, JYL; Chiu, PWY; Lau, JYW; Lau, LHS; Ling, RHY; Tse, YK; Wong, GLH; Wong, VWS, 2020)
" lansoprazole, a proton pump inhibitor, for treatment of gastric ulcer (GU) or duodenal ulcer (DU)."5.24Randomised clinical trial: efficacy and safety of vonoprazan vs. lansoprazole in patients with gastric or duodenal ulcers - results from two phase 3, non-inferiority randomised controlled trials. ( Miwa, H; Mori, Y; Nishimura, A; Sakaki, N; Sakurai, Y; Takanami, Y; Tatsumi, T; Uedo, N; Watari, J, 2017)
"Low-dose lansoprazole has not been intensively evaluated for its efficacy in the prevention of recurrent gastric or duodenal ulcers in patients receiving long-term non-steroidal anti-inflammatory drug (NSAID) therapy for pain relief in such diseases as rheumatoid arthritis, osteoarthritis, and low back pain."5.16Lansoprazole for secondary prevention of gastric or duodenal ulcers associated with long-term non-steroidal anti-inflammatory drug (NSAID) therapy: results of a prospective, multicenter, double-blind, randomized, double-dummy, active-controlled trial. ( Asaka, M; Ashida, K; Hiraishi, H; Hiramatsu, N; Kanto, T; Katsuo, S; Kontani, T; Matsui, S; Mizokami, Y; Sakaki, N; Soen, S; Sugano, K; Takei, Y; Takeuchi, T, 2012)
"The efficacy of low-dose lansoprazole has not been established for the prevention of recurrent gastric or duodenal ulcers in those receiving long-term low-dose aspirin (LDA) for cardiovascular and cerebrovascular protection."5.15Lansoprazole for secondary prevention of gastric or duodenal ulcers associated with long-term low-dose aspirin therapy: results of a prospective, multicenter, double-blind, randomized, double-dummy, active-controlled trial. ( Abe, S; Ashida, K; Chiba, T; Hiramatsu, N; Itabashi, T; Kanto, T; Matsui, S; Matsumoto, Y; Mizokami, Y; Sakaki, N; Shimada, K; Sugano, K; Uchiyama, S; Uemura, N, 2011)
"Subjects 18 years or older with osteoarthritis, without gastroduodenal ulcer or erosive esophagitis at baseline endoscopy, and a cardiovascular indication for prophylaxis low-dose (81 or 325 mg) aspirin were prescribed open-label aspirin and blindly randomized to celecoxib 200 mg/day or naproxen 500 mg twice daily plus lansoprazole 30 mg once daily."5.12Celecoxib plus aspirin versus naproxen and lansoprazole plus aspirin: a randomized, double-blind, endoscopic trial. ( Amer, F; Cryer, B; Goldstein, JL; Hunt, B, 2007)
"This analysis compared the efficacy of misoprostol, lansoprazole, and placebo in reducing the risk of gastric or duodenal ulcer recurrence in patients taking NSAIDs and low-dose aspirin."5.11Ulcer recurrence in high-risk patients receiving nonsteroidalanti-inflammatory drugs plus low-dose aspirin: results of a post HOC subanalysis. ( Amer, F; Christopoulos, NG; Goldstein, JL; Huang, B, 2004)
"Sixty-seven patients (49 with Zollinger-Ellison syndrome [ZES], 18 without), with basal acid output (BAO) >15 mmol/h or >5 mmol/h if post-antrectomy (n = 9, all ZES), were treated with individually optimized doses of lansoprazole (7."5.11Clinical outcome using lansoprazole in acid hypersecretors with and without Zollinger-Ellison syndrome: a 13-year prospective study. ( Hirschowitz, BI; Mohnen, J; Simmons, J, 2005)
"To compare the efficacy of lansoprazole and pantoprazole in treatment of active duodenal ulcer and Helicobacterpylori eradication."5.10In treatment of active duodenal ulcer and Helicobacter pylori eradication. ( Karaoglu, AO; Yasa, MH; Yukselen, V, 2003)
"To compare lansoprazole 30 mg once daily, lansoprazole 15 mg once daily and ranitidine 150 mg once nightly in the prevention of duodenal ulcer relapse in patients whose duodenal ulcers had been previously healed with lansoprazole 30 mg once daily or ranitidine 300 mg nightly."5.09Lansoprazole is superior to ranitidine as maintenance treatment for the prevention of duodenal ulcer relapse. ( Bardhan, KD; Crouch, SL; Crowe, J; Keeling, PN; Thompson, RP; Trewby, PN; Weir, D, 1999)
"Lansoprazole safely and effectively reduces duodenal ulcer recurrence and ulcer-related symptoms."5.09Double-blind comparison of lansoprazole 15 mg, lansoprazole 30 mg and placebo as maintenance therapy in patients with healed duodenal ulcers resistant to H2-receptor antagonists. ( Campbell, D; Haber, M; Jennings, DE; Kovacs, TO; Richter, J; Rose, P, 1999)
"The aim of this randomized, multicenter, double-masked, parallel-group study was to compare the efficacy of lansoprazole with that of omeprazole monotherapy in duodenal ulcer healing and prevention of relapse."5.09Lansoprazole versus omeprazole for duodenal ulcer healing and prevention of relapse: a randomized, multicenter, double-masked trial. ( Dobrilla, G; Fiocca, R; Piazzi, L, 1999)
"A health economic evaluation of triple therapy with lansoprazole, amoxicillin and clarithromycin versus 2 dual therapies (lansoprazole or omeprazole, each with amoxicillin) in the eradication of Helicobacter pylori in patients with duodenal ulcers was performed in parallel with a randomised clinical trial."5.09Cost effectiveness of Helicobacter pylori eradication therapies in patients with duodenal ulcer. An analysis of triple therapy versus two dual therapy alternatives. ( Norinder, A; Ohlin, B; Tennvall, GR, 1999)
"To compare two lansoprazole-based non-clarithromycin triple therapies and one dual therapy in a prospective double-blind placebo-controlled study of Helicobacter pylori eradication and duodenal ulcer healing."5.09Comparison of lansoprazole-based triple and dual therapy for treatment of Helicobacter pylori-related duodenal ulcer: an Asian multicentre double-blind randomized placebo controlled study. ( Carpio, RE; Fock, KM; Ho, J; Hu, FL; Hu, PJ; Huang, NX; Kachintorn, U; Kullavanijaya, P; Lam, SK; Lesmana, L; Li, YY; Manan, C; Perez, JY; Phornphutkul, K; Qian, SC; Wong, BC; Xiao, SD, 2000)
"The primary objective of the present study was to evaluate the efficacy of 30 and 60 mg of lansoprazole administered in combination with two antibiotics for 7 or 10 days in eradicating Helicobacter pylori in duodenal ulcer patients."5.09[Treatment of Helicobacter pylori infection with lansoprazole 30 mg or 60 mg combined with two antibiotics for duodenal ulcers]. ( Joubert-Collin, M; Lamouliatte, H; Perie, F, 2000)
"The aim of this study was to compare in an open, controlled and prospective trial the efficacy of one-week regimen using either lansoprazole (2 x 30 mg) + 2 x 500 mg metronidazole + 2 x 250 mg clarithromycin (group I, 60 cases) or ranitidine bismuth citrate (2 x 400 mg) + 2 x 500 mg metronidazole + 2 x 250 mg clarithromycin (group II, 61 cases) on the eradication of Hp infection in duodenal ulcer patients."5.09[Lansoprazole versus ranitidine bismuth citrate containing triple regimens for Helicobacter pylori eradication in patients with duodenal ulcer]. ( Buzás György, M; Illyés, G; Székely, E; Széles, I, 2000)
" Patients with gastric ulcer (GU) or duodenal ulcer (DU) were enrolled in this study; 583 eligible patients (GU, 325; DU, 258) were administered lansoprazole (30 mg/day for 8 weeks for GU, and the same dosage for 6 weeks for DU) as first-line therapy, and a half dose of H2RA as maintenance therapy for 12 months."5.09Peptic ulcer recurrence during maintenance therapy with H2-receptor antagonist following first-line therapy with proton pump inhibitor. ( Asaka, M; Asaki, S; Ashida, K; Harasawa, S; Hoshihara, Y; Kajiyama, G; Kaneko, E; Kobayashi, K; Muto, Y; Nakamura, T; Nakazawa, S; Ogawa, N; Sakaki, N; Takemoto, T; Yao, T, 2000)
" Fifty patients with active or scarred duodenal ulcer were randomized to lansoprazole or omeprazole for 1 to 4 weeks, with clarithromycin 250 mg twice a day and tinidazole 500 mg twice a day for the first week."5.09Long-term follow-up and serologic assessment after triple therapy with omeprazole or lansoprazole of Helicobacter-associated duodenal ulcer. ( Fanti, L; Guslandi, M; Ieri, R; Mezzi, G; Passaretti, S; Testoni, PA, 2001)
" pylori-positive duodenal ulcers were randomized to receive either lansoprazole 30 mg, clarithromycin 500 mg, and metronidazole 400 mg twice daily for 7 days (LCM-7) or lansoprazole 30 mg, clarithromycin 500 mg, metronidazole 400 mg, and bismuth subcitrate 240 mg twice daily for 3 days (LCMB-3)."5.09Three-day lansoprazole quadruple therapy for Helicobacter pylori-positive duodenal ulcers: a randomized controlled study. ( Chan, CK; Chu, KM; Fung, FM; Hu, FL; Hu, WH; Hui, WM; Kung, NN; Lai, KC; Lam, SK; Lau, GK; Liu, XG; Wang, WH; Wong, BC; Wong, WM; Yuen, MF, 2001)
"This study was undertaken to compare the efficacy of lansoprazole (LAN)-based triple therapy with that of RBC-based dual therapy in H pylori-infected patients with duodenal ulcer."5.09Lansoprazole-based triple therapy versus ranitidine bismuth citrate-based dual therapy in the eradication of Helicobacter pylori in patients with duodenal ulcer: a multicenter, randomized, double-dummy study. ( Belmonte, A; Cavaliere, C; Ciliberto, E; Fiocca, R; Frandina, C; Giglio, A; Luzza, F; Pallone, F; Saccà, N; Trimboli, V, 2001)
"To investigate Helicobacter pylori eradication in duodenal ulcer patients with a new regimen, lansoprazole 30 mg daily for one or four weeks plus twice daily tetracycline 500 mg, clarithromycin 250 mg, and metronidazole 400 mg."5.09Quadruple therapy for symptomatic spontaneous duodenal ulcer disease. ( Bateson, MC, 2001)
"To compare the efficacy of one-week versus two-week treatment with lansoprazole, amoxycillin and clarithromycin in inducing healing of Helicobacter pylori-positive duodenal ulcers as well as to investigate the role of several factors, determinant in the ulcer healing process."5.09Prolonging proton pump inhibitor-based anti-Helicobacter pylori treatment from one to two weeks in duodenal ulcer: is it worthwhile? ( Bianchi Porro, G; Cucino, C; Imbesi, V; Maconi, G; Russo, A, 2000)
" pylori positive duodenal ulcer were enrolled and randomly allocated into one of the five treatment groups: 1) group A: received lansoprazole 30 mg once daily for 2 weeks plus amoxicillin (AM) 500 mg and metronidazole (MZ) 500 mg twice daily for one week in the first week; 2) group B: the AM in group A was replaced by clarithromycin (CM) 250 mg; 3) group C: the MZ in group A was replaced by CM 250 mg; 4) group D: the AM and CM in group C was used for 2 wk; 5) group E: the CM in group D was doubled to 500 mg twice daily."5.09A multicenter study on eradication of Helicobacter pylori infection in patients with duodenal ulcer by lansoprazole-antibiotics combined therapy. ( Hsu, CT; Kuo, CF; Wang, CS; Wang, TH; Yang, JC; Yang, KC, 1999)
"Satisfactory antral biopsies were obtained from 119 duodenal ulcer patients before and after 4 wk of therapy with lansoprazole, ranitidine, or placebo."5.08The effects of short-term lansoprazole therapy on Helicobacter pylori infection and antral gastritis in duodenal ulcer patients. ( Atkinson, BF; Brightman, SA; Jhala, NC; McFarland, MM; Morale, B; Rubin, W, 1995)
"A randomized, single-blind study was designed to assess the effect of lansoprazole alone and lansoprazole plus amoxicillin on the healing and eradication rates in Helicobacter pylori-associated peptic ulcer disease."5.08Clinical efficacy of lansoprazole in eradication of Helicobacter pylori. ( Asaka, M; Kagaya, H; Katagiri, M; Katoh, M; Kudoh, M; Takeda, H, 1995)
"This study reports preliminary results of a controlled, multicenter trial on the quality of ulcer healing induced by lansoprazole (LPZ) or roxatidine (R) in gastric ulcer (GU) or duodenal ulcer (DU) patients."5.08Quality of peptic ulcer healing induced by lansoprazole and roxatidine. ( Fujino, MA; Kobayashi, K; Morozumi, A; Ohtsuka, H; Sano, S; Suzuki, Y; Tachikawa, H; Uchida, N; Ueda, F; Yamamoto, Y, 1995)
"The clinical usefulness of lansoprazole in the healing of gastric and duodenal ulcers, the S2-stage shift rate (white scarring rate), and endoscopic healing rate with respect to degree of gastric mucosal atrophy were investigated."5.08Clinical evaluation of lansoprazole in the treatment of peptic ulcers: initial healing and prevention of relapse. Tohoku Peptic Ulcer Study Group. ( Asaki, S; Hongo, M; Sakurada, H; Sato, A; Takeda, T; Toyota, T, 1995)
"In the present study, the effects of short-term treatment with lansoprazole on healing and recurrence of peptic ulcer were investigated."5.08The effect of lansoprazole treatment on the healing and relapse of peptic ulcer and serum levels of IgG anti-Helicobacter pylori antibody. ( Akimoto, K; Fukujin, H; Katoaka, A; Mashima, H; Mine, T; Nagasawa, J; Tajima, A; Takano, T; Tsuchida, T; Yasuda, H, 1995)
"In this double-blind randomized comparative study patients with active duodenal ulcers were treated with either 30 mg lansoprazole or 20 mg omeprazole in the morning."5.08Lansoprazole versus omeprazole in active duodenal ulcer. A double-blind, randomized, comparative study. ( Anker-Hansen, O; Carling, L; Ekström, P; Sellström, H; Sjöstedt, S; Unge, P, 1995)
"A double-blind, multicentre study was undertaken in 296 patients with endoscopically proven duodenal ulcer to compare the efficacy and safety of lansoprazole 15, 30 or 60 mg with placebo."5.08A comparison of three doses of lansoprazole (15, 30 and 60 mg) and placebo in the treatment of duodenal ulcer. The Lansoprazole Study Group. ( Avner, DL; Dorsch, ER; Greski-Rose, PA; Jennings, DE, 1995)
"To evaluate the efficacy of a second generation acid pump inhibitor-lansoprazole (L) a controlled clinical trial in 72 patients of duodenal ulcer was carried out with omeprazole (O) as control."5.08[A clinical trial of lansoprazole in the treatment of duodenal ulcer]. ( Chen, S; Pei, Y; Wang, B, 1995)
" pylori-positive duodenal ulcer were randomly assigned to receive one of the following three antiulcer regimens: (1) lansoprazole 30 mg b."5.08Comparison of two lansoprazole-antibiotic combinations (amoxycillin or classical triple therapy) for treatment of H. pylori infection in duodenal ulcer patients. ( Bargiggia, S; Bianchi Porro, G; Colombo, E; Maconi, G; Parente, F, 1996)
"We report long-term, up to 4 years, prospective treatment using lansoprazole in nine male patients with duodenal ulcers and a BAO of more than 15 mmol/h whose results are compared with those in 10 male Zollinger-Ellison syndrome patients with intact stomachs reported in detail in an accompanying paper."5.08Long-term treatment with lansoprazole of patients with duodenal ulcer and basal acid output of more than 15 mmol/h. ( Hirschowitz, BI; Mohnen, J; Shaw, S, 1996)
" pylori-positive gastritis with or without peptic ulcer, and compared with the classic 'Bazzoli regimen' (OCT: omeprazole, clarithromycin, tinidazole) in 60 matched patients."5.08Short-term low-dose triple therapy with azithromycin, metronidazole and lansoprazole appears highly effective for the eradication of Helicobacter pylori. ( Alvisi, V; Caselli, M; Gasbarrini, G; Gaudenzi, P; Luzzi, I; Ruina, M; Sartori, S; Trevisani, L; Tursi, A, 1997)
"Eighty patients with endoscopically proven active duodenal ulcer were randomized to take ranitidine or lansoprazole for 4-8 wk, together with clarithromycin 250 mg b."5.08Triple therapy with ranitidine or lansoprazole in the treatment of Helicobacter pylori-associated duodenal ulcer. ( Bargiggia, S; Bianchi Porro, G; Lazzaroni, M, 1997)
" pylori-infected patients with endoscopically documented duodenal ulcer either currently or within the past year were randomized to 14 days of (1) lansoprazole, 30 mg bid, plus amoxicillin, 1 gm tid; (2) lansoprazole, 30 mg tid, plus amoxicillin, 1 gm tid; (3) lansoprazole, 30 mg tid alone; or (4) amoxicillin, 1 gm tid alone."5.08Double-blind, multicenter evaluation of lansoprazole and amoxicillin dual therapy for the cure of Helicobacter pylori infection. ( Arora, A; Graham, D; Haber, M; Harford, W; Lanza, F; Rose, P; Siepman, N; Weissfeld, A, 1996)
" The aim of the present study was to assess efficacy and tolerability of the proton pump inhibitors lansoprazole given at bedtime as compared to ranitidine, both in acute and maintenance treatment of duodenal ulcer."5.08Bedtime administration of lansoprazole does not modify its greater efficacy vs ranitidine in the acute and long-term treatment of duodenal ulcer. Results from a multicentre, randomised, double blind clinical trial. ( Dattilo, M; Russo, A, 1997)
"In patients with active or a recent history of duodenal ulcer, a 14-day course of lansoprazole-based triple therapy without additional acid suppression therapy is highly effective in the eradication of H."5.08Triple versus dual therapy for eradicating Helicobacter pylori and preventing ulcer recurrence: a randomized, double-blind, multicenter study of lansoprazole, clarithromycin, and/or amoxicillin in different dosing regimens. ( Freston, J; Haber, M; Krause, R; Rose, P; Sahba, B; Schwartz, H; Siepman, N; Weissfeld, A, 1998)
" Fasting had no influence on the result of duodenal ulcer treatment by lansoprazole which was well tolerated."5.08[Effect of the observance of diurnal fast of Ramadan on duodenal ulcer healing with lansoprazole. Results of a prospective controlled study]. ( Ajmi, S; Mehdi, A, 1997)
"In order to explore the optimal regimens for the eradication of Helicobacter pylori (Hp), eighty-eight patients with duodenal ulcer (DU) or non-ulcer dyspepsia and Hp infection, defined by culture and histology, received the one-week triple therapy with clarithromycin (Cla), furazolidone (Fur) plus lansoprazole (Lan) or colloidal bismuth subcitrate (CBS)."5.08[Clarithromycin combined short-term triple therapies for eradication of Helicobacter pylori infection]. ( Liu, W; Lü, B; Xiao, S, 1996)
" Patients with duodenal ulcer were treated with lansoprazole alone (n = 11) or lansoprazole and amoxycillin (n = 12)."5.08Amount of Helicobacter pylori in gastric mucus during anti-H. pylori treatment. ( Arai, H; Furuta, T; Futami, H; Hanai, H; Kaneko, E; Takashima, M, 1998)
" pylori-infected duodenal ulcer patients we investigated the gastritis parameters in antral and corpus mucosa before treatment, after 6 and 12 months of therapy, and 6 months after termination of treatment with 15 mg lansoprazole or 150 mg ranitidine/day."5.08Changes in Helicobacter pylori-induced gastritis in the antrum and corpus during and after 12 months of treatment with ranitidine and lansoprazole in patients with duodenal ulcer disease. ( Kiel, G; Meining, A; Stolte, M, 1998)
"Sixty patients with active duodenal ulcers who tested positive for the rapid urease test had a C-14 UBT at 0 weeks (at enrollment) and at 6 and 12 weeks using 5 microCi (185 KBq) of C-14 urea."5.08Can the C-14 urea breath test replace follow-up endoscopic biopsies in patients treated for Helicobacter pylori infection? ( Ahuja, V; Bal, CS; Sharma, MP, 1998)
"In order to investigate whether chronic duodenal ulcer disease is a consequence of disturbed mucosal turnover and growth factor expression, we studied 16 patients with duodenal ulcers before, during, and after endoscopic healing with lansoprazole or sucralfate."5.08Effect of chronic duodenal ulceration and its treatment with lanzoprazole or sucralfate on gastroduodenal mucosal protein turnover and TGF-alpha, bFGF, and EGF receptor expression in humans. ( Marks, IN; O'Keefe, SJ; Ogden, J; Winter, T; Zhang, T, 1998)
"To study in a double-blind controlled manner the effects of lansoprazole 15 mg or 30 mg daily compared with ranitidine 300 mg once daily and placebo in the relieving of symptoms and healing of acute duodenal ulceration."5.07Double-blind comparison of lansoprazole, ranitidine, and placebo in the treatment of acute duodenal ulcer. Lansoprazole Study Group. ( Goff, J; Greski-Rose, P; Jennings, D; Lanza, F; Scowcroft, C, 1994)
"The purpose of this study was to compare duodenal ulcer healing, symptom relief, and safety of lansoprazole (a new proton pump inhibitor) given at doses of 30 mg and 60 mg, in the morning with ranitidine 300 mg at bedtime."5.07Improved symptom relief and duodenal ulcer healing with lansoprazole, a new proton pump inhibitor, compared with ranitidine. ( Bardhan, KD; Christian, J; Cochran, KM; Hawkey, CJ; Long, RG; Moules, IK; Wormsley, KG, 1993)
"The efficacy of lansoprazole (30 mg/d) and omeprazole (20 mg/d) has been assessed in active duodenal ulcer disease in 144 patients included in a multicentric, randomized, double-blind trial."5.07[Comparison of lansoprazole (30 mg) and omeprazole (20 mg) in the treatment of duodenal ulcer. A multicenter double-blind comparative trial]. ( Andrieu, J; Coste, T; Dupuis, J; Grimaud, JC; Julien, H; Lemerez, M; Licht, H; Petite, JP; Sallerin, V; Slama, JL, 1993)
"Forty-two patients with peptic ulceration of the duodenum, stomach or oesophagus, who had not responded to 3 or more months of high-dose treatment with ranitidine (450 or 600 mg/day), were treated with oral lansoprazole at 30-60 mg daily."5.07An open trial of long-term therapy with lansoprazole in patients with peptic ulceration resistant to extended high-dose ranitidine treatment. ( Arnold, R; Brunner, G; Fuchs, W; Hennig, U, 1993)
" Double-blind comparative studies with a beta-blocker, famotidine, in gastric ulcer (study 1) and in duodenal ulcer (study 2) were conducted."5.07[Double-blind controlled-clinical trials of lansoprazole in the treatment of peptic ulcer]. ( Ogawa, N, 1992)
" In this 2:1 randomized, double-blind, multicentre trial lansoprazole 30 mg am was compared to 40 mg famotidine nocte in 264 out-patients suffering from uncomplicated duodenal ulcer."5.07Lansoprazole versus famotidine: efficacy and tolerance in the acute management of duodenal ulceration. ( Grymbowski, T; Hennig, U; Hotz, J; Kleinert, R; Schwarz, JA, 1992)
" This randomized, double-blind multicentre trial studied the dose-response relationship of lansoprazole on ulcer healing and compared it with ranitidine in 314 out-patients with endoscopically assessed, symptomatic duodenal ulcer."5.07Dose-related healing of duodenal ulcer with the proton pump inhibitor lansoprazole. ( Barth, H; Dammann, HG; Hengels, KJ; Kleinert, R; Londong, W; Müller, P; Rohde, H; Simon, B, 1991)
"The proton pump inhibitors (PPIs) lansoprazole (LPZ) and omeprazole (OPZ) have been widely used for more than 20 years in the treatment of acid-related diseases such as gastro-duodenal ulcers and reflux esophagitis."4.89Discovery of lansoprazole and its unique pharmacological properties independent from anti-secretory activity. ( Satoh, H, 2013)
"An 11-year-old boy with Helicobacter pylori-associated duodenal ulcer was successfully treated with a combination of lansoprazole, amoxicillin, and clarithromycin."4.82Helicobacter heilmannii infection in a child after successful eradication of Helicobacter pylori: case report and review of literature. ( Iinuma, K; Kato, S; Minoura, T; Ohyauchi, M; Ozawa, K; Sekine, H; Shimosegawa, T, 2005)
" Although PPIs have been introduced into the therapy of acute peptic ulcer disease at different daily, oral doses of 20 mg (omeprazole and rabeprazole), 30 mg (lansoprazole) and 40 mg (pantoprazole), the data suggest that the optimal dose of lansoprazole, omeprazole and pantoprazole, with respect to the acute treatment of peptic ulcers and moderate to severe gastroesophageal reflux disease (GERD), is about 30-40 mg daily."4.80Relative efficacies of gastric proton pump inhibitors: their clinical and pharmacological basis. ( Horbach, S; Kromer, W; Lühmann, R, 1999)
"The aim was to compare the clinical efficacy of lansoprazole with the efficacies of ranitidine and famotidine in order to rank this drug in the hierarchy of duodenal ulcer treatments."4.79Meta-analysis of randomized clinical trials comparing lansoprazole with ranitidine or famotidine in the treatment of acute duodenal ulcer. ( Agostini, H; Lemaire, M; Poynard, T, 1995)
" In the treatment of gastric ulcer, analysis of all studies that have compared lansoprazole, a newly developed proton pump inhibitor, and H2-receptor antagonists has shown a statistically significant difference for a higher healing rate with lansoprazole."4.78Progress with proton pump inhibitors in acid peptic disease: treatment of duodenal and gastric ulcer. ( Florent, C, 1993)
" There are the results of studies in which the known quantitative parameters of duodenal reflux in the duodenal ulcer patients were simulated to identify their influence on the disintegration of enterosoluble dosage forms and the bioavailability of proton pump inhibitors (in healthy volunteers, patients with gasritis, exacerbation and remission of peptic ulcer disease the pharmacokinetics of lansoprazole, intragastric pH-metry with floating capsule for teleradio-pH-metry were investigated, and in an in vitro study the dissolution tests of proton pump inhibitors with pH 3 and pH = 4 were made)."3.81[THE FEATURES OF SECRETION AND STOMACH MOTOR PROCESSES IN PATIENTS WITH DUODENAL ULCERS AS A CAUSE FOR REDUCING BIOAVAILABILITY OF PROTON PUMP INHIBITORS]. ( Prokofiev, AB; Serebrova, SY; Zhuravleva, MV, 2015)
"Lansoprazole is an effective acid pump inhibitor acting at the final enzymatic step of the acid secretory pathway of the parietal cell, decreasing gastric acid secretion regardless of the primary stimulus."3.77Lansoprazole. A review of its pharmacodynamic and pharmacokinetic properties and its therapeutic efficacy in acid-related disorders. ( Barradell, LB; Faulds, D; McTavish, D, 1992)
" Cysteamine inhibits the release of somatostatin and induces the formation of duodenal ulcers in rats."3.73Enhanced ghrelin secretion in rats with cysteamine-induced duodenal ulcers. ( Arakawa, M; Fukuhara, S; Hibi, T; Hosoda, H; Ishii, H; Kangawa, K; Kitajima, M; Masaoka, T; Minegishi, Y; Suzuki, H, 2005)
"Biopsy specimens were taken from the duodenal ulcer patients who underwent gastroscopy before and after the treatment of Lansoprazole."3.73[Distribution of Helicobacter pylori in stomach before and after the administration of Lansoprazole]. ( Cheng, HY; Dong, XY; Jin, Z; Lin, SR; Ye, SM; Zhou, LY, 2005)
" pylori infection who had gastritis, duodenal ulcer (DU) or gastric ulcer (GU) received 1 week's triple therapy of lansoprazole 30 g once daily (OD), amoxycillin 250 mg qid and clarithromycin 250 mg tid."3.72Low dose, one-week triple therapy (lanzoprazole, amoxycillin, clarithromycin) for eradication of Helicobacter pylori infection. ( Uthaisaengsook, W, 2003)
"Gastric juice pH, ammonia concentration in gastric juice, serum gastrin level, and grade of gastritis in accordance with the Sydney System were determined for patients with gastric ulcer (GU) and duodenal ulcer (DU) before and after treatment with lansoprazole and amoxicillin, and results were compared with those of H."3.70Effect of Helicobacter pylori infection on gastric juice pH. ( Arai, H; Baba, S; Furuta, T; Futami, H; Hanai, H; Kajimura, M; Kaneko, E; Takashima, M, 1998)
" Likewise, pantoprazole showed the healing promoting action on chronic duodenal ulcers induced by acetic acid, and this effect was also more potent when compared to omeprazole or lansoprazole."3.70Effects of pantoprazole, a novel H+/K+-ATPase inhibitor, on duodenal ulcerogenic and healing responses in rats: a comparative study with omeprazole and lansoprazole. ( Kato, S; Konaka, A; Nishijima, M; Takeuchi, K; Yasuhiro, T, 1999)
"To evaluate endogenous and exogenous factors affecting the quality of ulcer healing produced by proton pump inhibitors, gastric acid pH, serum gastrin, and serum pepsinogen (PG) I and II were measured in peptic ulcer patients before and after treatment with lansoprazole 30 mg once daily."3.69Factors affecting quality of ulcer healing after lansoprazole treatment. ( Hanai, H; Ito, G; Kaneko, E; Nakagawara, M; Nawano, M; Ooi, S; Watanabe, F, 1995)
"One-week therapy with lansoprazole, amoxicillin and clarithromycin is highly effective in duodenal ulcer healing and symptom improvement."3.69Duodenal ulcer healing after 7-day treatment: a pilot study with lansoprazole, amoxicillin and clarithromycin. ( Hentschel, E; Schütze, K, 1995)
"To study the efficiency of the combination lansoprazole and amoxicillin on the eradication of Helicobacter pylori and duodenal ulcer healing."3.69[Erradicating treatment of Helicobacter pylori with lansoprazole and amoxicillin in duodenal ulcer patients]. ( Aller, R; Alvarez Baleriola, I; Bermejo, F; Boixeda, D; Gisbert, JP; Martín de Argila, C, 1996)
"The 1-week triple therapy was safe and effective for eradicating H."2.69Safety and efficacy of one-week triple therapy for eradicating Helicobacter pylori in children. ( Asaka, M; Iinuma, K; Kato, S; Ohnuma, K; Ritsuno, H; Sugiyama, T, 1998)
" The optimal dosage and duration of treatment need to be specified."2.68Lansoprazole versus lansoprazole plus amoxicillin treatment for eradication of Helicobacter pylori in patients with gastric ulcer. ( Fujita, N; Hisano, K; Kobayashi, T; Kurokawa, I; Ochiai, T; Sugiyama, T; Yabana, T; Yachi, A, 1995)
"Lansoprazole 30 mg/day was administered to 124 gastric ulcer (GU) patients and 57 duodenal ulcer (DU) patients."2.68Peptic ulcer therapy with lansoprazole and Helicobacter pylori eradication. ( Kato, T; Ogoshi, K; Sakagawa, T, 1995)
"pylori infection and the ulcer recurrence rate after 1 year were investigated."2.68Effects of lansoprazole plus amoxycillin on the cure of Helicobacter pylori infection in Japanese peptic ulcer patients. ( Asaka, M; Hokari, K; Kagaya, H; Katagiri, M; Kato, M; Koshiyama, T; Kudo, M; Nishikawa, K; Sugiyama, T; Sukegawa, M; Takeda, H, 1996)
"When lansoprazole alone was administered to the patients, H."2.68[Effect of treatment with lansoprazole and amoxicillin in combination on healing process of duodenal ulcer]. ( Maruyama, M, 1996)
"Time to ulcer recurrence was significantly longer (P < 0."2.68Prevention of duodenal ulcer recurrence with 15 mg lansoprazole: a double-blind placebo-controlled study. The Lansoprazole Study Group. ( Goff, J; Greski-Rose, P; Jennings, D; Jhala, N; Lanza, F; Silvers, D; Winters, J, 1997)
"His only medical history was mild Alzheimer's disease diagnosed 6 months prior."2.52Upper gastrointestinal bleed associated with cholinesterase inhibitor use. ( Kok, KS; Loke, Y; Southgate, J, 2015)
"Lansoprazole is a proton pump inhibitor that reduces gastric acid secretion in a dose-dependent manner via inhibition of H+/K+-adenosine triphosphatase in gastric parietal cells."2.41An overview of the pharmacology, efficacy, safety and cost-effectiveness of lansoprazole. ( Bown, RL, 2002)
"When lansoprazole was used as monotherapy, the mean Hp eradication was 6% in four studies."2.39Adjuvant therapy for Helicobacter pylori eradication: role of lansoprazole in clinical studies. ( Lamouliatte, H, 1995)
"Gastric metaplasia was endoscopically and histologically evaluated before and after eradication of this bacterium."1.32Long-term follow-up of gastric metaplasia after eradication of Helicobacter pylori. ( Sano, T; Urakami, Y, 2003)
"Lactoferrin (Lf) is an iron-binding glycoprotein present in milk, lacrimae, saliva, and gastroduodenal secretions."1.30Relation of lactoferrin levels in gastric mucosa with Helicobacter pylori infection and with the degree of gastric inflammation. ( Ikemura, N; Imoto, I; Misaki, M; Nakao, K; Shibata, T; Taguchi, Y; Takaji, S; Yamauchi, K; Yamazaki, N, 1997)
"Lansoprazole was mostly prescribed in patients with reflux oesophagitis (55."1.30A prospective follow-up study of 5669 users of lansoprazole in daily practice. ( Claessens, A; Heerdink, E; Lamers, CB; Leufkens, H; van Eijk, J, 1997)
"Lansoprazole has a cytotoxic action against this organism, the MIC being 2."1.29Effect of lansoprazole in mono-, dual-, or triple therapy on Helicobacter pylori eradication. ( Kawano, S; Murakami, M; Saita, H; Tsuji, S, 1996)

Research

Studies (150)

TimeframeStudies, this research(%)All Research%
pre-19901 (0.67)18.7374
1990's93 (62.00)18.2507
2000's44 (29.33)29.6817
2010's8 (5.33)24.3611
2020's4 (2.67)2.80

Authors

AuthorsStudies
Hou, X1
Meng, F1
Wang, J1
Sha, W1
Chiu, CT1
Chung, WC1
Gu, L1
Kudou, K1
Chong, CF1
Zhang, S1
Tan, ND2
Liu, XW2
Liu, CX2
Li, SB2
Chen, HH2
Li, X2
Wu, H2
Liao, AJ2
Zhen, YB1
Shen, PZ1
Huo, LJ1
Liu, HL1
Shi, RH1
Zhang, BQ1
Zhang, ZY2
Wang, JN1
Zhan, Q1
Deng, H1
Shu, X1
Tuo, BG1
Wang, QZ1
Du, SY1
Qi, LZ1
Zhang, GX1
Peng, Q1
Wang, BM1
Ye, B1
Chen, MH2
Xiao, YL2
Miao, XP1
Li, FF1
Guo, QH1
Tang, YP1
Xia, M1
Liu, YL1
Chen, HX1
Zhang, Y1
Wong, GLH1
Lau, LHS1
Ching, JYL1
Tse, YK1
Ling, RHY1
Wong, VWS1
Chiu, PWY1
Lau, JYW1
Chan, FKL1
Sakaki, N5
Ashida, K5
Mizokami, Y3
Chiba, T2
Matsui, S3
Kanto, T3
Uemura, N2
Hiramatsu, N3
Sugano, K3
Kok, KS1
Loke, Y1
Southgate, J1
Serebrova, SY1
Zhuravleva, MV1
Prokofiev, AB1
Miwa, H1
Uedo, N1
Watari, J1
Mori, Y1
Sakurai, Y1
Takanami, Y1
Nishimura, A1
Tatsumi, T1
Pellicano, R1
Inoue, M1
Okada, H1
Hori, S1
Kawahara, Y1
Kawano, S2
Takenaka, R1
Toyokawa, T1
Onishi, Y1
Shiratori, Y1
Yamamoto, K1
Matsumoto, Y1
Itabashi, T1
Abe, S1
Shimada, K1
Uchiyama, S1
Kontani, T1
Katsuo, S1
Takei, Y1
Asaka, M6
Soen, S1
Takeuchi, T1
Hiraishi, H1
Satoh, H2
Ishibashi, S1
Iwakiri, R1
Shimoda, R1
Ootani, H1
Kawasaki, S1
Tadano, J1
Kikkawa, A1
Ootani, A1
Oda, K1
Fujise, T1
Yoshida, T1
Tsunada, S1
Sakata, H1
Fujimoto, K1
Boon, YH1
Vu, C1
Kaushik, S1
Cheng, CS1
Chiu, TC1
Chian, LC1
Murakami, K1
Sato, R1
Okimoto, T1
Nasu, M1
Fujioka, T1
Kodama, M1
Kagawa, J1
Sato, S1
Abe, H1
Arita, T1
Cherniakevich, SA1
Babkova, IV1
Mikhalev, AI1
Urakami, Y2
Sano, T1
Fedele, E1
Lai, YC1
Wang, TH2
Huang, SH1
Yang, SS1
Wu, CH1
Chen, TK1
Lee, CL1
Kamiya, T1
Kobayashi, Y1
Misu, N1
Hirako, M1
Adachi, H1
Nagao, T1
Shikano, M1
Matsuhisa, E1
Ando, T1
Kimura, G1
Uthaisaengsook, W1
Chaudhary, A1
Ahuja, V3
Bal, CS2
Das, B1
Pandey, RM1
Sharma, MP4
Tiesmeier, J1
Hinner, H1
Kraus, J1
Schuppert, F1
Yukselen, V1
Yasa, MH1
Karaoglu, AO1
Goldstein, JL2
Huang, B1
Amer, F2
Christopoulos, NG1
Hirschowitz, BI2
Simmons, J1
Mohnen, J2
Arkkila, PE1
Seppälä, K1
Kosunen, TU1
Sipponen, P1
Mäkinen, J1
Rautelin, H1
Färkkilä, M1
Kato, S3
Ozawa, K1
Sekine, H1
Ohyauchi, M1
Shimosegawa, T1
Minoura, T1
Iinuma, K2
Fukuhara, S1
Suzuki, H4
Masaoka, T1
Arakawa, M1
Hosoda, H1
Minegishi, Y1
Kangawa, K1
Ishii, H4
Kitajima, M1
Hibi, T3
Jin, Z1
Dong, XY1
Lin, SR1
Ye, SM1
Zhou, LY1
Cheng, HY1
Güliter, S1
Keleş, H1
Ozkurt, ZN1
Cengiz, DU1
Kolukisa, E1
Shiwani, MH1
Cryer, B1
Hunt, B1
Dam, C1
Bygum, A1
Ahmed, W1
Ali, A1
Qureshi, H1
Zuberi, SJ1
Shamsi, ZU1
Jhala, NC1
McFarland, MM1
Brightman, SA1
Morale, B1
Rubin, W1
Atkinson, BF1
Sugiyama, T3
Hisano, K1
Ochiai, T1
Fujita, N1
Kobayashi, T1
Yabana, T1
Kurokawa, I1
Yachi, A1
Katoh, M1
Kudoh, M1
Kagaya, H2
Katagiri, M2
Takeda, H2
Furuta, T5
Futami, H4
Arai, H4
Hanai, H5
Kaneko, E7
Takimoto, T1
Ido, K1
Taniguchi, Y1
Satoh, K1
Saifuku, K1
Kihira, K2
Yoshida, Y1
Kimura, K1
Nakata, H1
Itoh, H1
Nishioka, S1
Shirai, T1
Takagi, A1
Kurumada, T1
Ohta, U1
Kobayashi, H1
Harasawa, S2
Miwa, T1
Fujino, MA1
Morozumi, A1
Kobayashi, K2
Ueda, F1
Suzuki, Y1
Uchida, N1
Tachikawa, H1
Sano, S1
Ohtsuka, H1
Yamamoto, Y1
Asaki, S2
Sato, A1
Sakurada, H1
Takeda, T1
Hongo, M1
Toyota, T1
Sakaguchi, M1
Tanaka, M1
Takiuchi, H1
Egashira, Y1
Katsu, K1
Ito, G1
Nakagawara, M1
Watanabe, F1
Ooi, S1
Nawano, M1
Hoshino, E1
Umeda, N1
Sano, J1
Miki, K1
Yahagi, N1
Oka, M1
Kimura, M2
Miyashita, H1
Mine, T2
Yasuda, H1
Akimoto, K1
Katoaka, A1
Mashima, H1
Tajima, A1
Fukujin, H1
Tsuchida, T1
Takano, T1
Nagasawa, J1
Ohashi, T1
Sakata, J1
Haraguchi, Y1
Eto, T1
Ogoshi, K1
Kato, T2
Sakagawa, T1
Ponce, J1
Nos, P1
Lamouliatte, H3
Kohli, Y1
Azuma, T1
Ito, S1
Hirai, M1
Michel, P1
Duhamel, C1
Bazin, B1
Raoul, JL1
Person, B1
Bigard, MA1
Legoux, JL1
Sallerin, V2
Colin, R1
Ekström, P1
Carling, L1
Unge, P1
Anker-Hansen, O1
Sjöstedt, S1
Sellström, H1
Florent, C1
Lanza, F3
Goff, J2
Scowcroft, C1
Jennings, D2
Greski-Rose, P2
Seifert, E1
Pallone, F2
Luzza, F2
Delle Fave, G1
Annibale, B1
Marcheggiano, A1
Biancone, L1
Torsoli, A1
Capurso, L1
Hawkey, CJ1
Long, RG1
Bardhan, KD4
Wormsley, KG1
Cochran, KM1
Christian, J1
Moules, IK1
Petite, JP1
Slama, JL1
Licht, H1
Lemerez, M1
Coste, T1
Andrieu, J1
Grimaud, JC1
Julien, H1
Dupuis, J1
Mignon, M2
Vallot, T1
Brunner, G1
Arnold, R1
Hennig, U2
Fuchs, W1
Cadiot, G1
Vissuzaine, C1
Pospai, D1
Ruszniewski, P1
Potet, F1
Avner, DL1
Dorsch, ER1
Jennings, DE2
Greski-Rose, PA1
Poynard, T1
Lemaire, M1
Agostini, H1
Schütze, K1
Hentschel, E1
Pei, Y1
Wang, B1
Chen, S1
Parente, F1
Maconi, G2
Bargiggia, S2
Colombo, E1
Bianchi Porro, G3
Stermer, E1
Levy, N1
Sito, E1
Konturek, PC1
Bielański, W1
Kwiecień, N1
Konturek, SJ1
Baniukiewicz, A1
Jedynak, M1
Gabryelewicz, A1
Hahn, EG1
de Boer, WA1
van Etten, RJ1
Schade, RW1
Ouwehand, ME1
Schneeberger, PM1
Tytgat, GN2
Shaw, S1
Dhar, A2
Gupta, VK1
Srinivasan, S1
Logan, RP1
Kato, M1
Kudo, M1
Sukegawa, M1
Koshiyama, T1
Nishikawa, K1
Hokari, K1
Maruyama, M1
Murakami, M1
Saita, H2
Tsuji, S1
Gisbert, JP2
Boixeda, D2
Alvarez Baleriola, I1
Martín de Argila, C2
Bermejo, F1
Aller, R1
Baba, S2
Caselli, M1
Trevisani, L1
Tursi, A1
Sartori, S1
Ruina, M1
Luzzi, I1
Gaudenzi, P1
Alvisi, V1
Gasbarrini, G1
Lazzaroni, M1
Seki, H1
Nakao, K1
Imoto, I1
Ikemura, N1
Shibata, T1
Takaji, S1
Taguchi, Y1
Misaki, M1
Yamauchi, K1
Yamazaki, N1
Kayser, S1
Flury, R1
Zbinden, R1
Fried, M1
Wirth, HP1
Leufkens, H1
Claessens, A1
Heerdink, E1
van Eijk, J1
Lamers, CB1
Harford, W1
Arora, A1
Graham, D1
Haber, M3
Weissfeld, A2
Rose, P3
Siepman, N2
Jaup, BK1
Silvers, D1
Winters, J1
Jhala, N1
Misiewicz, JJ2
Harris, AW2
Levi, S2
O'Morain, C2
Cooper, BT2
Kerr, GD2
Dixon, MF2
Langworthy, H2
Piper, D2
Russo, A2
Dattilo, M1
Suzuki, M3
Mori, M2
Miyayama, A1
Iwai, N1
Tsunematsu, N1
Oonuki, M1
Schwartz, H1
Krause, R1
Sahba, B1
Freston, J1
Mehdi, A1
Ajmi, S1
Liu, W1
Lü, B1
Xiao, S1
Takashima, M3
Kajimura, M1
Treiber, G1
Lambert, JR1
Bal, C1
Meining, A1
Kiel, G1
Stolte, M1
Cayla, R1
Zerbib, F1
Forestier, S1
de Mascarel, A1
Joubert-Collin, M2
Mégraud, F1
Ritsuno, H1
Ohnuma, K1
Suzuki, J1
Kobayasi, I1
Fujita, T1
Kitahora, T2
Nagahashi, S2
Zhang, T1
O'Keefe, SJ1
Winter, T1
Marks, IN1
Ogden, J1
Liu, WZ1
Xiao, SD2
Shi, Y1
Wu, SM1
Zhang, DZ1
Xu, WW1
Takeuchi, K1
Konaka, A1
Nishijima, M1
Yasuhiro, T1
Cammarota, G1
Papa, A1
Cianci, R1
Cannizzaro, O1
Armuzzi, A1
Gasbarrini, A1
Addolorato, G1
Gasbarrini, GB1
Crowe, J1
Thompson, RP1
Trewby, PN1
Keeling, PN1
Weir, D1
Crouch, SL1
Kovacs, TO1
Campbell, D1
Richter, J1
Kromer, W1
Horbach, S1
Lühmann, R1
Dobrilla, G1
Piazzi, L1
Fiocca, R2
Tennvall, GR1
Norinder, A1
Ohlin, B1
Sou, Y1
Takahashi, Y1
Yoshinaga, T1
Matsukawa, Y1
Sekikawa, A1
Nakazawa, T1
Shio, S1
Kohigashi, K1
Bustamante, M1
Stollman, N1
Wong, BC2
Hu, FL2
Qian, SC1
Huang, NX1
Li, YY1
Hu, PJ1
Manan, C1
Lesmana, L1
Carpio, RE1
Perez, JY1
Fock, KM1
Kachintorn, U1
Phornphutkul, K1
Kullavanijaya, P1
Ho, J1
Lam, SK2
Gomollón, F1
Santolaria, S1
Ducóns, JA1
Guirao, R1
Vera, J1
Montoro, M1
Shashidhar, H1
Peters, J1
Lin, CH1
Rabah, R1
Thomas, R1
Tolia, V1
Perie, F1
Di Mario, F1
Battaglia, F1
Dal Bò, N1
Leandro, G1
Benedetti, E1
Bottona, E1
Caroli, A1
Costan-Biedo, F1
De Bastiani, R1
Germanà, B1
Andrea Grassi, S1
Madia, D1
Marcon, V1
Marin, R1
Monica, F1
Olivieri, P1
Orzes, N1
Pilotto, A1
Ronzani, G1
Saggioro, A1
Tafner, G1
Buzás György, M1
Székely, E1
Illyés, G1
Széles, I1
Thomson, AB1
Hoshihara, Y1
Nakamura, T1
Kajiyama, G1
Ogawa, N2
Yao, T1
Muto, Y1
Nakazawa, S1
Takemoto, T1
Fanti, L1
Ieri, R1
Mezzi, G1
Testoni, PA1
Passaretti, S1
Guslandi, M1
Shirai, N1
Xiao, F1
Sugimura, H1
Ohashi, K1
Ishizaki, T1
Wang, WH1
Wong, WM1
Lau, GK1
Fung, FM1
Kung, NN1
Chu, KM1
Lai, KC1
Hu, WH1
Liu, XG1
Chan, CK1
Yuen, MF1
Hui, WM1
Bardou, M1
Giglio, A1
Ciliberto, E1
Belmonte, A1
Cavaliere, C1
Saccà, N1
Frandina, C1
Trimboli, V1
Meyer, JM1
Silliman, NP1
Dixon, CA1
Siepman, NY1
Sugg, JE1
Hopkins, RJ1
Bateson, MC1
Imbesi, V1
Cucino, C1
Yang, JC1
Yang, KC1
Hsu, CT1
Wang, CS1
Kuo, CF1
Herszényi, L1
Tulassay, Z1
Ikeda, S1
Tamamuro, T1
Hamashima, C1
Mai, AL1
Mai, KT1
Miyazawa, M1
Suzuki, K1
Bown, RL1
Barradell, LB1
Faulds, D1
McTavish, D1
Berlin, I1
Molinier, P1
Duchier, A1
Cournot, A1
Durrel, J1
Dellatolas, F1
Duchier, J1
Hotz, J1
Kleinert, R2
Grymbowski, T1
Schwarz, JA1
Inatomi, N1
Nagaya, H1
Takami, K1
Shino, A1
Londong, W1
Barth, H1
Dammann, HG1
Hengels, KJ1
Müller, P1
Rohde, H1
Simon, B1

Clinical Trials (11)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Prevention of Recurrent Idiopathic Gastroduodenal Ulcer Bleeding: a Double-blind Randomized Trial[NCT01180179]Phase 4228 participants (Actual)Interventional2010-06-30Completed
Efficacy of Vonoprazan Versus Intravenous Proton Pump Inhibitors for Prevention of Rebleeding in High Risk Peptic Ulcers Bleeding After Successful Endoscopic Hemostasis[NCT05005910]Early Phase 1194 participants (Actual)Interventional2021-09-01Completed
A Phase 3, Randomized, Double Blind, Double-Dummy, Multicenter, Parallel Group Comparison Study to on Efficacy and Safety of Oral Once-Daily Administration of TAK-438 20 mg Comparing With AG-1749 in Patients With Duodenal Ulcer[NCT01452724]Phase 3372 participants (Actual)Interventional2011-10-31Completed
A Phase 3, Randomized, Double Blind, Double-Dummy, Multicenter, Parallel Group Comparison Study to on Efficacy and Safety of Oral Once-Daily Administration of TAK-438 20 mg Comparing With AG-1749 in Patients With Gastric Ulcer.[NCT01452711]Phase 3482 participants (Actual)Interventional2011-11-30Completed
The Phase 2 Study of FP-10, the Food Ingredient Derived From Milk Casein, on the Eradication Rates of Helicobacter Pylori by a Triple Therapy With Lansoprazole, Amoxicillin, and Clarithromycin[NCT00281047]Phase 2/Phase 3138 participants Interventional2006-01-31Recruiting
Long-Term Study of the Efficacy and Safety of Lansoprazole in the Treatment of Zollinger-Ellison and Other Acid Hypersecretors[NCT00204373]Phase 472 participants (Actual)Interventional2003-03-31Completed
European Registry on the Management of Helicobacter Pylori Infection[NCT02328131]10,000 participants (Anticipated)Observational2013-06-30Recruiting
A Randomized, Double-Blind, Phase 3 Study to Compare the Efficacy and Safety of Lansoprazole 30 mg QD and Naproxen 500 mg BID Versus Celecoxib 200 mg QD in Risk Reduction of Non Steroidal Anti-Inflammatory-Associated Ulcers in Osteoarthritis Subjects Taki[NCT00175032]Phase 31,045 participants (Actual)Interventional2003-07-31Completed
Pharmacodynamic Dose-Response of S-Tenatoprazole-Na (STU-Na) 30 mg, 60 mg, 90 mg and 120 mg in Healthy Volunteers[NCT00284908]Phase 132 participants (Actual)Interventional2006-09-30Completed
Assessment of the Healing Rate of Erosive or Ulcerative Esophagitis After Two and Four Weeks of Treatment With S-Tenatoprazole-Na (STU-Na) 15 mg, 30 mg, 60 mg, 90 mg and Esomeprazole 40 mg. A Multicenter, Randomized, Double-Blind, Parallel Group Study.[NCT00282555]Phase 2450 participants Interventional2006-02-28Suspended
Pharmacogenomics-Based Tailor-Made Strategy for Eradication of Helicobacter Pylori[NCT00149084]Phase 3296 participants Interventional2003-04-30Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Long-term Medical(Non-surgical)Control of Gastric Acid Production Assessed From Time of Study Enrollment, up to 240 Months Post Enrollment.

number of participants with control of gastric acid production (NCT00204373)
Timeframe: up to 240 months from study enrollment

Interventionparticipants (Number)
Single Group72

The Median Survival From the Time of Diagnosis.

The median survival from the time of diagnosis (NCT00204373)
Timeframe: survival or up to 240 months

Interventionyears (Median)
Single Group6.6

Reviews

19 reviews available for lansoprazole and Duodenal Ulcer

ArticleYear
Upper gastrointestinal bleed associated with cholinesterase inhibitor use.
    BMJ case reports, 2015, Sep-29, Volume: 2015

    Topics: Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Donepezil; Duodenal Ulcer; Endoscop

2015
[Proton pump inhibitors, a family of drugs in continuous expansion].
    Minerva gastroenterologica e dietologica, 2000, Volume: 46, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Inflammatory Agents, Non-Steroidal; Barrett E

2000
Discovery of lansoprazole and its unique pharmacological properties independent from anti-secretory activity.
    Current pharmaceutical design, 2013, Volume: 19, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Inflammatory Agents, Non-Steroidal; Duodenal

2013
Helicobacter heilmannii infection in a child after successful eradication of Helicobacter pylori: case report and review of literature.
    Journal of gastroenterology, 2005, Volume: 40, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Chil

2005
[Lansoprazol].
    Gastroenterologia y hepatologia, 1995, Volume: 18, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Controlled Clinical Trials as Topic; Duo

1995
Adjuvant therapy for Helicobacter pylori eradication: role of lansoprazole in clinical studies.
    Journal of clinical gastroenterology, 1995, Volume: 20 Suppl 1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Bacterial Agents; Anti-Ulcer Agents; Chemotherapy, Adj

1995
Progress with proton pump inhibitors in acid peptic disease: treatment of duodenal and gastric ulcer.
    Clinical therapeutics, 1993, Volume: 15 Suppl B

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Duodenal Ulcer; Gastritis; Gastroesophag

1993
[Lansoprazole--profile of a new proton pump inhibitor].
    Leber, Magen, Darm, 1994, Volume: 24, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Dose-Response Relationship, Drug; Drug A

1994
Acute treatment of duodenal ulcer: experience with lansoprazole.
    Alimentary pharmacology & therapeutics, 1993, Volume: 7 Suppl 1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Drug Administration Schedule; Duodenal U

1993
Meta-analysis of randomized clinical trials comparing lansoprazole with ranitidine or famotidine in the treatment of acute duodenal ulcer.
    European journal of gastroenterology & hepatology, 1995, Volume: 7, Issue:7

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acute Disease; Anti-Ulcer Agents; Duodenal Ulcer; Famotidin

1995
The impact of Helicobacter pylori eradication on peptic ulcer healing.
    The American journal of gastroenterology, 1998, Volume: 93, Issue:7

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Antacids; Anti-Ulcer Agents; Benzimidazoles; Duodenal Ulcer

1998
Relative efficacies of gastric proton pump inhibitors: their clinical and pharmacological basis.
    Pharmacology, 1999, Volume: 59, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Benzimidazoles; Dose-Response Relationsh

1999
Relative efficacies of gastric proton pump inhibitors: their clinical and pharmacological basis.
    Pharmacology, 1999, Volume: 59, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Benzimidazoles; Dose-Response Relationsh

1999
Relative efficacies of gastric proton pump inhibitors: their clinical and pharmacological basis.
    Pharmacology, 1999, Volume: 59, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Benzimidazoles; Dose-Response Relationsh

1999
Relative efficacies of gastric proton pump inhibitors: their clinical and pharmacological basis.
    Pharmacology, 1999, Volume: 59, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Benzimidazoles; Dose-Response Relationsh

1999
The efficacy of proton-pump inhibitors in acute ulcer bleeding: a qualitative review.
    Journal of clinical gastroenterology, 2000, Volume: 30, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Benzimidazoles; Duodenal Ulcer; Humans;

2000
Are the orally administered proton pump inhibitors equivalent? A comparison of lansoprazole, omeprazole, pantoprazole, and rabeprazole.
    Current gastroenterology reports, 2000, Volume: 2, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Benzimidazoles; Drug Interactions; Duode

2000
[H2 receptor antagonists and proton pump inhibitors: principles and rules of use].
    La Revue du praticien, 2001, Apr-15, Volume: 51, Issue:7

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Age Factors; Aged; Anti-Ulcer Agents; Benzimidazoles; Child

2001
Helicobacter pylori and early duodenal ulcer status post-treatment: a review.
    Helicobacter, 2001, Volume: 6, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Infective Agents; Anti-Ulcer Agents; Bismuth; Clinical

2001
[Comparative study of proton pump inhibitors].
    Orvosi hetilap, 2001, Sep-09, Volume: 142, Issue:36

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Bacterial Agents; Anti-Ulcer Agents; Benzimidazoles; C

2001
An overview of the pharmacology, efficacy, safety and cost-effectiveness of lansoprazole.
    International journal of clinical practice, 2002, Volume: 56, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Digestive System Diseases; Duodenal Ulcer; Dyspepsia; Enzym

2002
Lansoprazole. A review of its pharmacodynamic and pharmacokinetic properties and its therapeutic efficacy in acid-related disorders.
    Drugs, 1992, Volume: 44, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Biological Availability; Duodenal Ulcer;

1992

Trials

91 trials available for lansoprazole and Duodenal Ulcer

ArticleYear
Vonoprazan non-inferior to lansoprazole in treating duodenal ulcer and eradicating Helicobacter pylori in Asian patients.
    Journal of gastroenterology and hepatology, 2022, Volume: 37, Issue:7

    Topics: Amoxicillin; Anti-Ulcer Agents; Clarithromycin; Double-Blind Method; Drug Therapy, Combination; Duod

2022
Efficacy of keverprazan for duodenal ulcer: A phase II randomized, double-blind, parallel-controlled trial.
    Journal of gastroenterology and hepatology, 2022, Volume: 37, Issue:11

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Double-Blind Method; Duodenal Ulcer; Fol

2022
Efficacy and Safety of Keverprazan Compared With Lansoprazole in the Treatment of Duodenal Ulcer: A Phase III, Randomized, Double-Blind, Multicenter Trial.
    Clinical and translational gastroenterology, 2023, 07-01, Volume: 14, Issue:7

    Topics: Anti-Ulcer Agents; Double-Blind Method; Duodenal Ulcer; Humans; Lansoprazole

2023
Prevention of recurrent idiopathic gastroduodenal ulcer bleeding: a double-blind, randomised trial.
    Gut, 2020, Volume: 69, Issue:4

    Topics: Aged; Aged, 80 and over; Double-Blind Method; Duodenal Ulcer; Famotidine; Female; Histamine H2 Antag

2020
Endoscopic evaluation of low-dose aspirin-induced gastric and duodenal ulcers during prophylaxis with lansoprazole.
    Hepato-gastroenterology, 2013, Volume: 60, Issue:124

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Aspirin; Comorbidity; Double-Blind

2013
Randomised clinical trial: efficacy and safety of vonoprazan vs. lansoprazole in patients with gastric or duodenal ulcers - results from two phase 3, non-inferiority randomised controlled trials.
    Alimentary pharmacology & therapeutics, 2017, Volume: 45, Issue:2

    Topics: Adult; Aged; Anti-Ulcer Agents; Double-Blind Method; Duodenal Ulcer; Endoscopy; Female; Humans; Lans

2017
Randomised clinical trial: efficacy and safety of vonoprazan vs. lansoprazole in patients with gastric or duodenal ulcers - results from two phase 3, non-inferiority randomised controlled trials.
    Alimentary pharmacology & therapeutics, 2017, Volume: 45, Issue:2

    Topics: Adult; Aged; Anti-Ulcer Agents; Double-Blind Method; Duodenal Ulcer; Endoscopy; Female; Humans; Lans

2017
Randomised clinical trial: efficacy and safety of vonoprazan vs. lansoprazole in patients with gastric or duodenal ulcers - results from two phase 3, non-inferiority randomised controlled trials.
    Alimentary pharmacology & therapeutics, 2017, Volume: 45, Issue:2

    Topics: Adult; Aged; Anti-Ulcer Agents; Double-Blind Method; Duodenal Ulcer; Endoscopy; Female; Humans; Lans

2017
Randomised clinical trial: efficacy and safety of vonoprazan vs. lansoprazole in patients with gastric or duodenal ulcers - results from two phase 3, non-inferiority randomised controlled trials.
    Alimentary pharmacology & therapeutics, 2017, Volume: 45, Issue:2

    Topics: Adult; Aged; Anti-Ulcer Agents; Double-Blind Method; Duodenal Ulcer; Endoscopy; Female; Humans; Lans

2017
Randomised clinical trial: efficacy and safety of vonoprazan vs. lansoprazole in patients with gastric or duodenal ulcers - results from two phase 3, non-inferiority randomised controlled trials.
    Alimentary pharmacology & therapeutics, 2017, Volume: 45, Issue:2

    Topics: Adult; Aged; Anti-Ulcer Agents; Double-Blind Method; Duodenal Ulcer; Endoscopy; Female; Humans; Lans

2017
Randomised clinical trial: efficacy and safety of vonoprazan vs. lansoprazole in patients with gastric or duodenal ulcers - results from two phase 3, non-inferiority randomised controlled trials.
    Alimentary pharmacology & therapeutics, 2017, Volume: 45, Issue:2

    Topics: Adult; Aged; Anti-Ulcer Agents; Double-Blind Method; Duodenal Ulcer; Endoscopy; Female; Humans; Lans

2017
Randomised clinical trial: efficacy and safety of vonoprazan vs. lansoprazole in patients with gastric or duodenal ulcers - results from two phase 3, non-inferiority randomised controlled trials.
    Alimentary pharmacology & therapeutics, 2017, Volume: 45, Issue:2

    Topics: Adult; Aged; Anti-Ulcer Agents; Double-Blind Method; Duodenal Ulcer; Endoscopy; Female; Humans; Lans

2017
Randomised clinical trial: efficacy and safety of vonoprazan vs. lansoprazole in patients with gastric or duodenal ulcers - results from two phase 3, non-inferiority randomised controlled trials.
    Alimentary pharmacology & therapeutics, 2017, Volume: 45, Issue:2

    Topics: Adult; Aged; Anti-Ulcer Agents; Double-Blind Method; Duodenal Ulcer; Endoscopy; Female; Humans; Lans

2017
Randomised clinical trial: efficacy and safety of vonoprazan vs. lansoprazole in patients with gastric or duodenal ulcers - results from two phase 3, non-inferiority randomised controlled trials.
    Alimentary pharmacology & therapeutics, 2017, Volume: 45, Issue:2

    Topics: Adult; Aged; Anti-Ulcer Agents; Double-Blind Method; Duodenal Ulcer; Endoscopy; Female; Humans; Lans

2017
Does pretreatment with lansoprazole influence Helicobacter pylori eradication rate and quality of life?
    Digestion, 2010, Volume: 81, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adult; Amoxicillin; Clarithromycin; D

2010
Lansoprazole for secondary prevention of gastric or duodenal ulcers associated with long-term low-dose aspirin therapy: results of a prospective, multicenter, double-blind, randomized, double-dummy, active-controlled trial.
    Journal of gastroenterology, 2011, Volume: 46, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Anti-Ulcer Agents; Aspirin; Double-Blind Method; Duod

2011
Lansoprazole for secondary prevention of gastric or duodenal ulcers associated with long-term non-steroidal anti-inflammatory drug (NSAID) therapy: results of a prospective, multicenter, double-blind, randomized, double-dummy, active-controlled trial.
    Journal of gastroenterology, 2012, Volume: 47, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer A

2012
Eradication rates of clarithromycin-resistant Helicobacter pylori using either rabeprazole or lansoprazole plus amoxicillin and clarithromycin.
    Alimentary pharmacology & therapeutics, 2002, Volume: 16, Issue:11

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agent

2002
Density of Helicobacter pylori may affect the efficacy of eradication therapy and ulcer healing in patients with active duodenal ulcers.
    World journal of gastroenterology, 2003, Volume: 9, Issue:7

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agent

2003
Rank order of success favors longer duration of imidazole-based therapy for Helicobacter pylori in duodenal ulcer disease: a randomized pilot study.
    Helicobacter, 2004, Volume: 9, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Amoxicillin; Anti-Bacterial Agents

2004
In treatment of active duodenal ulcer and Helicobacter pylori eradication.
    Hepato-gastroenterology, 2003, Volume: 50 Suppl 2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Benz

2003
Ulcer recurrence in high-risk patients receiving nonsteroidalanti-inflammatory drugs plus low-dose aspirin: results of a post HOC subanalysis.
    Clinical therapeutics, 2004, Volume: 26, Issue:10

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, N

2004
Clinical outcome using lansoprazole in acid hypersecretors with and without Zollinger-Ellison syndrome: a 13-year prospective study.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2005, Volume: 3, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Ulcer Agents; Duodenal Ulcer; Esophagitis

2005
Helicobacter pylori eradication as the sole treatment for gastric and duodenal ulcers.
    European journal of gastroenterology & hepatology, 2005, Volume: 17, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Bacterial Agents; Anti-Inflammatory Agent

2005
Celecoxib plus aspirin versus naproxen and lansoprazole plus aspirin: a randomized, double-blind, endoscopic trial.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2007, Volume: 5, Issue:10

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovas

2007
The effects of short-term lansoprazole therapy on Helicobacter pylori infection and antral gastritis in duodenal ulcer patients.
    The American journal of gastroenterology, 1995, Volume: 90, Issue:10

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Double-B

1995
Lansoprazole versus lansoprazole plus amoxicillin treatment for eradication of Helicobacter pylori in patients with gastric ulcer.
    Journal of clinical gastroenterology, 1995, Volume: 20 Suppl 2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Ulcer Agents; Drug Therapy, Combination;

1995
Clinical efficacy of lansoprazole in eradication of Helicobacter pylori.
    Journal of clinical gastroenterology, 1995, Volume: 20 Suppl 2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Anti-Ulcer Agents; Drug Administration

1995
Effects of lansoprazole with or without amoxicillin on ulcer healing: relation to eradication of Helicobacter pylori.
    Journal of clinical gastroenterology, 1995, Volume: 20 Suppl 2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Ulcer Agents; Duodenal Ulcer; Gastric Jui

1995
Efficacy of lansoprazole in eradication of Helicobacter pylori.
    Journal of clinical gastroenterology, 1995, Volume: 20 Suppl 2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Bacterial Agents; Anti-Ulcer Agents; Benzimidaz

1995
Efficacy of lansoprazole and amoxicillin in eradicating Helicobacter pylori: evaluation using 13C-UBT and Monoclonal H. pylori antibody testing.
    Journal of clinical gastroenterology, 1995, Volume: 20 Suppl 2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Ulcer Agents; Antibodies, Bacterial; Anti

1995
Eradication of Helicobacter pylori with lansoprazole, amoxicillin, and plaunotol in duodenal ulcer patients.
    Journal of clinical gastroenterology, 1995, Volume: 20 Suppl 2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Amoxicillin; Anti-Ulcer Agents; Diterpenes; Dr

1995
Quality of peptic ulcer healing induced by lansoprazole and roxatidine.
    Journal of clinical gastroenterology, 1995, Volume: 20 Suppl 2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Duodenal

1995
Clinical evaluation of lansoprazole in the treatment of peptic ulcers: initial healing and prevention of relapse. Tohoku Peptic Ulcer Study Group.
    Journal of clinical gastroenterology, 1995, Volume: 20 Suppl 2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Atrophy; Duodenal Ulcer; Gastric Mucosa;

1995
Lansoprazole for maintenance therapy of peptic ulcer disease: weekend full-dose or everyday half-dose administration?
    Journal of clinical gastroenterology, 1995, Volume: 20 Suppl 2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Drug Administration Schedule; Duo

1995
The effect of lansoprazole treatment on the healing and relapse of peptic ulcer and serum levels of IgG anti-Helicobacter pylori antibody.
    Journal of clinical gastroenterology, 1995, Volume: 20 Suppl 2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Antibodi

1995
Effect of lansoprazole on peptic ulcers.
    Journal of clinical gastroenterology, 1995, Volume: 20 Suppl 2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Duodenal Ulcer; Female; Helicobacter Inf

1995
Peptic ulcer therapy with lansoprazole and Helicobacter pylori eradication.
    Journal of clinical gastroenterology, 1995, Volume: 20 Suppl 2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Duodenal Ulcer; Helicobacter Infections;

1995
Lansoprazole treatment of Helicobacter pylori-positive peptic ulcers.
    Journal of clinical gastroenterology, 1995, Volume: 20 Suppl 1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Drug Therapy, Combination; Duodenal Ulce

1995
[Lansoprazole versus ranitidine in the prevention of early recurrences of digestive hemorrhages from gastroduodenal ulcers. Randomized double-blind multicenter study].
    Gastroenterologie clinique et biologique, 1994, Volume: 18, Issue:12

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Double-B

1994
Lansoprazole versus omeprazole in active duodenal ulcer. A double-blind, randomized, comparative study.
    Scandinavian journal of gastroenterology, 1995, Volume: 30, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Double-Blind Method; Duodenal Ulcer; Female; Humans; Lansop

1995
Double-blind comparison of lansoprazole, ranitidine, and placebo in the treatment of acute duodenal ulcer. Lansoprazole Study Group.
    The American journal of gastroenterology, 1994, Volume: 89, Issue:8

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acute Disease; Adult; Anti-Ulcer Agents; Double-Blind Metho

1994
Lansoprazole and Helicobacter pylori infection.
    Clinical therapeutics, 1993, Volume: 15 Suppl B

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Anti-Ulcer Agents; Double-Blind Method;

1993
Improved symptom relief and duodenal ulcer healing with lansoprazole, a new proton pump inhibitor, compared with ranitidine.
    Gut, 1993, Volume: 34, Issue:10

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Anti-Ulcer Agents; Double-Blind Me

1993
[Comparison of lansoprazole (30 mg) and omeprazole (20 mg) in the treatment of duodenal ulcer. A multicenter double-blind comparative trial].
    Gastroenterologie clinique et biologique, 1993, Volume: 17, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adult; Anti-Ulcer Agents; Double-Blin

1993
Acute treatment of duodenal ulcer: experience with lansoprazole.
    Alimentary pharmacology & therapeutics, 1993, Volume: 7 Suppl 1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Drug Administration Schedule; Duodenal U

1993
An open trial of long-term therapy with lansoprazole in patients with peptic ulceration resistant to extended high-dose ranitidine treatment.
    Alimentary pharmacology & therapeutics, 1993, Volume: 7 Suppl 1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Dose-Response Relationship, Drug; Drug A

1993
A comparison of three doses of lansoprazole (15, 30 and 60 mg) and placebo in the treatment of duodenal ulcer. The Lansoprazole Study Group.
    Alimentary pharmacology & therapeutics, 1995, Volume: 9, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Abdominal Pain; Adult; Aged; Anti-Ulcer Agents; Double-Blin

1995
[A clinical trial of lansoprazole in the treatment of duodenal ulcer].
    Zhonghua nei ke za zhi, 1995, Volume: 34, Issue:9

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Ulcer Agents; Duodenal Ulcer; Female; H(+

1995
Comparison of two lansoprazole-antibiotic combinations (amoxycillin or classical triple therapy) for treatment of H. pylori infection in duodenal ulcer patients.
    Alimentary pharmacology & therapeutics, 1996, Volume: 10, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Ulcer Agents; Antitrichomonal Agents; Dru

1996
One week treatment with omeprazole, clarithromycin and tinidazole or lansoprazole, amoxicillin and metronidazole for cure of Helicobacter pylori infection in duodenal ulcer patients.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1996, Volume: 47, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agent

1996
4-day lansoprazole quadruple therapy: a highly effective cure for Helicobacter pylori infection.
    The American journal of gastroenterology, 1996, Volume: 91, Issue:9

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Bacterial Agents; Bismuth; Drug Therapy, Combination;

1996
Long-term treatment with lansoprazole of patients with duodenal ulcer and basal acid output of more than 15 mmol/h.
    Alimentary pharmacology & therapeutics, 1996, Volume: 10, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Duodenal Ulcer; Enzyme Inhibitors

1996
Effects of lansoprazole plus amoxycillin on the cure of Helicobacter pylori infection in Japanese peptic ulcer patients.
    Alimentary pharmacology & therapeutics, 1996, Volume: 10, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adult; Aged; Amoxicillin; Anti-Ulcer

1996
[Effect of treatment with lansoprazole and amoxicillin in combination on healing process of duodenal ulcer].
    Nihon Ika Daigaku zasshi, 1996, Volume: 63, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Amoxicillin; Drug Therapy, Combination; Duoden

1996
Short-term low-dose triple therapy with azithromycin, metronidazole and lansoprazole appears highly effective for the eradication of Helicobacter pylori.
    European journal of gastroenterology & hepatology, 1997, Volume: 9, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adult; Aged; Anti-Bacterial Agents; A

1997
Triple therapy with ranitidine or lansoprazole in the treatment of Helicobacter pylori-associated duodenal ulcer.
    The American journal of gastroenterology, 1997, Volume: 92, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Bacterial Agents; Anti-Ulcer Agents; Clar

1997
[Comparative effect of lansoprazole/amoxicillin with omeprazole/amoxicillin for the eradication of Helicobacter pylori in patients with duodenal ulcer].
    Schweizerische medizinische Wochenschrift, 1997, Apr-26, Volume: 127, Issue:17

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Amoxicillin; Anti-Ulcer Age

1997
Double-blind, multicenter evaluation of lansoprazole and amoxicillin dual therapy for the cure of Helicobacter pylori infection.
    Helicobacter, 1996, Volume: 1, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Anti-Ulcer Agents; Clarithromycin; Diar

1996
Prevention of duodenal ulcer recurrence with 15 mg lansoprazole: a double-blind placebo-controlled study. The Lansoprazole Study Group.
    Digestive diseases and sciences, 1997, Volume: 42, Issue:12

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Ulcer Agents; Biopsy; Double-Blind Method

1997
One week triple therapy for Helicobacter pylori: a multicentre comparative study. Lansoprazole Helicobacter Study Group.
    Gut, 1997, Volume: 41, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Amoxicillin; Anti-Ulcer Age

1997
Bedtime administration of lansoprazole does not modify its greater efficacy vs ranitidine in the acute and long-term treatment of duodenal ulcer. Results from a multicentre, randomised, double blind clinical trial.
    Italian journal of gastroenterology and hepatology, 1997, Volume: 29, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Anti-Ulcer Agents; Bed Rest; Dose-

1997
Triple versus dual therapy for eradicating Helicobacter pylori and preventing ulcer recurrence: a randomized, double-blind, multicenter study of lansoprazole, clarithromycin, and/or amoxicillin in different dosing regimens.
    The American journal of gastroenterology, 1998, Volume: 93, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer

1998
[Effect of the observance of diurnal fast of Ramadan on duodenal ulcer healing with lansoprazole. Results of a prospective controlled study].
    Gastroenterologie clinique et biologique, 1997, Volume: 21, Issue:11

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Duodenal Ulcer; Fasting; Female;

1997
[Clarithromycin combined short-term triple therapies for eradication of Helicobacter pylori infection].
    Zhonghua nei ke za zhi, 1996, Volume: 35, Issue:12

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithrom

1996
Amount of Helicobacter pylori in gastric mucus during anti-H. pylori treatment.
    Journal of gastroenterology and hepatology, 1998, Volume: 13, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Anti-Ulcer Agents; Drug Therapy, Combin

1998
Lansoprazole and secnidazole with clarithromycin, amoxycillin or pefloxacin in the eradication of Helicobacter pylori in a developing country.
    Alimentary pharmacology & therapeutics, 1998, Volume: 12, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer

1998
Changes in Helicobacter pylori-induced gastritis in the antrum and corpus during and after 12 months of treatment with ranitidine and lansoprazole in patients with duodenal ulcer disease.
    Alimentary pharmacology & therapeutics, 1998, Volume: 12, Issue:8

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Ulcer Agents; Duodenal Ulcer; Female; Gas

1998
Incidence of duodenal ulcer healing after 1 week of proton pump inhibitor triple therapy for eradication of Helicobacter pylori. The Lansoprazole Helicobacter Study Group.
    Alimentary pharmacology & therapeutics, 1998, Volume: 12, Issue:8

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer

1998
Dual therapy using a double dose of lansoprazole with amoxicillin versus triple therapy using a double dose of lansoprazole, amoxicillin, and clarithromycin to eradicate Helicobacter pylori infection: results of a prospective randomized open study.
    The American journal of gastroenterology, 1998, Volume: 93, Issue:9

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Amoxicillin; Anti-Ulcer Agents; Clarithromycin

1998
Safety and efficacy of one-week triple therapy for eradicating Helicobacter pylori in children.
    Helicobacter, 1998, Volume: 3, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer

1998
Can the C-14 urea breath test replace follow-up endoscopic biopsies in patients treated for Helicobacter pylori infection?
    Clinical nuclear medicine, 1998, Volume: 23, Issue:12

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Bacterial Agents; Anti-Ulcer Agents; Biopsy; Br

1998
Effect of chronic duodenal ulceration and its treatment with lanzoprazole or sucralfate on gastroduodenal mucosal protein turnover and TGF-alpha, bFGF, and EGF receptor expression in humans.
    Digestive diseases and sciences, 1998, Volume: 43, Issue:12

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Chronic Disease; Duodenal Ulcer;

1998
[Previous treatment with omeprazole and H. pylori: does it diminish the eradication efficacy of the "new" triple therapies of one week's duration?].
    Medicina clinica, 1998, Nov-28, Volume: 111, Issue:18

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agent

1998
Furazolidone-containing short-term triple therapies are effective in the treatment of Helicobacter pylori infection.
    Alimentary pharmacology & therapeutics, 1999, Volume: 13, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Bacterial Agents; Anti-Infective Agents, Local;

1999
Three-day antibiotic therapy with azithromycin and tinidazole plus lansoprazole or pantoprazole to cure Helicobacter pylori infection: a pilot study.
    European journal of gastroenterology & hepatology, 1999, Volume: 11, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Anti-Bacterial Agents; Anti-Ulcer

1999
Lansoprazole is superior to ranitidine as maintenance treatment for the prevention of duodenal ulcer relapse.
    Alimentary pharmacology & therapeutics, 1999, Volume: 13, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Aged, 80 and over; Double-Blind Me

1999
Double-blind comparison of lansoprazole 15 mg, lansoprazole 30 mg and placebo as maintenance therapy in patients with healed duodenal ulcers resistant to H2-receptor antagonists.
    Alimentary pharmacology & therapeutics, 1999, Volume: 13, Issue:7

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Ulcer Agents; Double-Blind Method; Drug R

1999
Lansoprazole versus omeprazole for duodenal ulcer healing and prevention of relapse: a randomized, multicenter, double-masked trial.
    Clinical therapeutics, 1999, Volume: 21, Issue:8

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Anti-Ulcer Agents; Double-Blind Me

1999
Cost effectiveness of Helicobacter pylori eradication therapies in patients with duodenal ulcer. An analysis of triple therapy versus two dual therapy alternatives.
    PharmacoEconomics, 1999, Volume: 16, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Amoxicillin; Anti-Ulcer Age

1999
Comparison of lansoprazole-based triple and dual therapy for treatment of Helicobacter pylori-related duodenal ulcer: an Asian multicentre double-blind randomized placebo controlled study.
    Alimentary pharmacology & therapeutics, 2000, Volume: 14, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Aged, 80 and over; Amoxicillin; An

2000
A prospective trial of lansoprazole triple therapy for pediatric Helicobacter pylori infection.
    Journal of pediatric gastroenterology and nutrition, 2000, Volume: 30, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Amoxicillin; Anti-Bacterial Agents; Biop

2000
[Treatment of Helicobacter pylori infection with lansoprazole 30 mg or 60 mg combined with two antibiotics for duodenal ulcers].
    Gastroenterologie clinique et biologique, 2000, Volume: 24, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agent

2000
Cure of Helicobacter pylori-positive active duodenal ulcer patients: a double-blind, multicentre, 12-month study comparing a two-week dual vs a one-week triple therapy. GISU (Interdisciplinary Group for Ulcer Study).
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2000, Volume: 32, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acute Disease; Adult; Aged; Aged, 80 and over; Amoxicillin;

2000
[Lansoprazole versus ranitidine bismuth citrate containing triple regimens for Helicobacter pylori eradication in patients with duodenal ulcer].
    Orvosi hetilap, 2000, Jul-30, Volume: 141, Issue:31

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Bacterial Agents; Anti-Ulcer Agents; Bismuth; C

2000
Peptic ulcer recurrence during maintenance therapy with H2-receptor antagonist following first-line therapy with proton pump inhibitor.
    Journal of gastroenterology, 2000, Volume: 35, Issue:11

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Duodenal Ulcer; Female; Histamine

2000
Long-term follow-up and serologic assessment after triple therapy with omeprazole or lansoprazole of Helicobacter-associated duodenal ulcer.
    Journal of clinical gastroenterology, 2001, Volume: 32, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Bacterial Agents; Anti-Ulcer Agents; Antibodies

2001
Effect of genotypic differences in CYP2C19 on cure rates for Helicobacter pylori infection by triple therapy with a proton pump inhibitor, amoxicillin, and clarithromycin.
    Clinical pharmacology and therapeutics, 2001, Volume: 69, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Aryl

2001
Three-day lansoprazole quadruple therapy for Helicobacter pylori-positive duodenal ulcers: a randomized controlled study.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adolescent; Adult; Aged; Antacids; An

2001
Lansoprazole-based triple therapy versus ranitidine bismuth citrate-based dual therapy in the eradication of Helicobacter pylori in patients with duodenal ulcer: a multicenter, randomized, double-dummy study.
    Clinical therapeutics, 2001, Volume: 23, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Anti-Ulcer Agents; Bismuth; Clarit

2001
Quadruple therapy for symptomatic spontaneous duodenal ulcer disease.
    Postgraduate medical journal, 2001, Volume: 77, Issue:909

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Clarithr

2001
Prolonging proton pump inhibitor-based anti-Helicobacter pylori treatment from one to two weeks in duodenal ulcer: is it worthwhile?
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2000, Volume: 32, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adult; Amoxicillin; Anti-Bacterial Ag

2000
A multicenter study on eradication of Helicobacter pylori infection in patients with duodenal ulcer by lansoprazole-antibiotics combined therapy.
    Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 1999, Volume: 32, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Clarithrom

1999
Treatment with a proton pump inhibitor promotes corpus gastritis in patients with Helicobacter pylori-infected antrum-predominant gastritis.
    Alimentary pharmacology & therapeutics, 2002, Volume: 16, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adult; Aged; Benzimidazoles; Biopsy;

2002
[Double-blind controlled-clinical trials of lansoprazole in the treatment of peptic ulcer].
    Nihon rinsho. Japanese journal of clinical medicine, 1992, Volume: 50, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenosine Triphosphatases; Adolescent; Adult; Aged; Anti-Ul

1992
Lansoprazole. A review of its pharmacodynamic and pharmacokinetic properties and its therapeutic efficacy in acid-related disorders.
    Drugs, 1992, Volume: 44, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Biological Availability; Duodenal Ulcer;

1992
Dose ranging study of lansoprazole, a new proton pump inhibitor, in patients with high gastric acid secretion.
    European journal of clinical pharmacology, 1992, Volume: 43, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenosine Triphosphatases; Adult; Double-Blind Method; Drug

1992
Lansoprazole versus famotidine: efficacy and tolerance in the acute management of duodenal ulceration.
    Alimentary pharmacology & therapeutics, 1992, Volume: 6, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Ulcer Agents; Double-Blind Method; Duoden

1992
Dose-related healing of duodenal ulcer with the proton pump inhibitor lansoprazole.
    Alimentary pharmacology & therapeutics, 1991, Volume: 5, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Anti-Ulcer Agents; Dose-Response R

1991

Other Studies

42 other studies available for lansoprazole and Duodenal Ulcer

ArticleYear
[THE FEATURES OF SECRETION AND STOMACH MOTOR PROCESSES IN PATIENTS WITH DUODENAL ULCERS AS A CAUSE FOR REDUCING BIOAVAILABILITY OF PROTON PUMP INHIBITORS].
    Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2015, Issue:9

    Topics: Adolescent; Adult; Aged; Duodenal Ulcer; Female; Gastric Mucosa; Humans; Hydrogen-Ion Concentration;

2015
Normalization of phospholipids concentration of the gastric mucosa was observed in patients with peptic ulcer after eradication of Helicobacter pylori.
    Helicobacter, 2002, Volume: 7, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer

2002
One week regimen of esomeprazole based triple therapy is sufficient for duodenal ulcer healing and Helicobacter pylori eradication in patients with duodenal ulcer disease.
    European journal of gastroenterology & hepatology, 2002, Volume: 14, Issue:8

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Clarithromycin; Drug Administration Schedule;

2002
[Results of pre- and postoperative treatment of complicated duodenal ulcers with proton pump inhibitors ].
    Klinicheskaia meditsina, 2002, Volume: 80, Issue:9

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Drug Therapy, Combination; Duodenal Ulce

2002
Long-term follow-up of gastric metaplasia after eradication of Helicobacter pylori.
    The journal of medical investigation : JMI, 2003, Volume: 50, Issue:1-2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Amoxicillin; Cicatrix; Convalescence; Drug The

2003
[Is gastric and duodenal ulcer drug-treatable or surgical disease?].
    Chirurgia italiana, 1997, Volume: 49, Issue:1-2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Duodenal Ulcer; Humans; Lansoprazole; Om

1997
Gastric myoelectrical activity in patients with recurrent gastric or duodenal ulcers.
    Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi, 2003, Volume: 39, Issue:1-2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Duodenal Ulcer; Endoscopy, Digest

2003
Low dose, one-week triple therapy (lanzoprazole, amoxycillin, clarithromycin) for eradication of Helicobacter pylori infection.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2003, Volume: 86, Issue:7

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Amoxicillin; Clarithromycin; Drug Therapy, Com

2003
[Chronic upper abdominal pain without improvement after using proton pump inhibitors].
    Deutsche medizinische Wochenschrift (1946), 2004, Jul-09, Volume: 129, Issue:28-29

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Abdominal Pain; Anti-Ulcer Agents; Azathioprine; Duodenal U

2004
Enhanced ghrelin secretion in rats with cysteamine-induced duodenal ulcers.
    American journal of physiology. Gastrointestinal and liver physiology, 2005, Volume: 289, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Cysteamine; Duodenal Ulcer; Gas

2005
[Distribution of Helicobacter pylori in stomach before and after the administration of Lansoprazole].
    Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2005, Apr-18, Volume: 37, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Duodenal Ulcer; Gastric Mucosa; Gastriti

2005
Can lansoprazole, amoxicillin, and clarithromycin combination still be used as a first-line therapy for eradication of helicobacter pylori?
    The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2005, Volume: 16, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acute Disease; Adult; Amoxicillin; Anti-Bacterial Agents; A

2005
Cholecystoduodenal fistula secondary to penetrating duodenal ulcer: a case of conservative management.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2006, Volume: 16, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Anti-Infective Agents; Anti-Ulcer Agents; Duodenal Ul

2006
Subacute cutaneous lupus erythematosus induced or exacerbated by proton pump inhibitors.
    Acta dermato-venereologica, 2008, Volume: 88, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Autoantibodies; Duodenal Ulcer; Esophagitis; Female; Humans

2008
Lansoprazole--a new proton pump inhibitor.
    JPMA. The Journal of the Pakistan Medical Association, 1995, Volume: 45, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Anti-Ulcer Agents; Duodenal Ulcer;

1995
Second proton-pump inhibitor marketed.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1995, Aug-01, Volume: 52, Issue:15

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Duodenal Ulcer; Esophagitis; Humans; Lan

1995
Clinical study on the pathophysiology and treatment of PPI-resistant ulcers.
    Journal of clinical gastroenterology, 1995, Volume: 20 Suppl 2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Drug Resistance; Duodenal Ulcer; Gastric

1995
Factors affecting quality of ulcer healing after lansoprazole treatment.
    Journal of clinical gastroenterology, 1995, Volume: 20 Suppl 2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Age Factors; Alcohol Drinking; Anti-Ulcer Agents; Duodenal

1995
Lansoprazole.
    The Medical letter on drugs and therapeutics, 1995, Jul-21, Volume: 37, Issue:953

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Controlled Clinical Trials as Topic; Cos

1995
[Effect of prolonged treatment with proton pump inhibitors on serum gastrin levels and the fundus mucosa. Preliminary results].
    Gastroenterologie clinique et biologique, 1995, Volume: 19, Issue:10

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Duodenal Ulcer; Enzyme Inhi

1995
Duodenal ulcer healing after 7-day treatment: a pilot study with lansoprazole, amoxicillin and clarithromycin.
    Zeitschrift fur Gastroenterologie, 1995, Volume: 33, Issue:11

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Amoxicillin; Anti-Bacterial Agents

1995
Helicobacter pylori and lanzoprazole.
    The American journal of gastroenterology, 1996, Volume: 91, Issue:8

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Duodenal Ulcer; Gastritis; Helicobacter

1996
Re: short-term treatment with lansoprazole.
    The American journal of gastroenterology, 1996, Volume: 91, Issue:10

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Duodenal Ulcer; Helicobacter Infections;

1996
The chemotherapeutic effects of H+/K+ inhibitors on Helicobacter pylori infection.
    Pharmacology & therapeutics, 1996, Volume: 69, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Down-Regulation; Duodenal Ulcer; Enzyme Inhibitors; Helicob

1996
Effect of lansoprazole in mono-, dual-, or triple therapy on Helicobacter pylori eradication.
    Journal of gastroenterology, 1996, Volume: 31 Suppl 9

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Ulcer Agents; Drug Therapy, Combination;

1996
[Erradicating treatment of Helicobacter pylori with lansoprazole and amoxicillin in duodenal ulcer patients].
    Revista clinica espanola, 1996, Volume: 196, Issue:9

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Drug

1996
Percentage changes in serum pepsinogens are useful as indices of eradication of Helicobacter pylori.
    The American journal of gastroenterology, 1997, Volume: 92, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Anti-Bacterial Agents; Duodenal Ulcer;

1997
Gastric metaplasia and Helicobacter pylori.
    The American journal of gastroenterology, 1997, Volume: 92, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Amoxicillin; Anti-Infective Agents; Anti-Ulcer

1997
Relation of lactoferrin levels in gastric mucosa with Helicobacter pylori infection and with the degree of gastric inflammation.
    The American journal of gastroenterology, 1997, Volume: 92, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Ammonia; Anti-Bacterial Agents; Anti-Ulcer Agents; Biomarke

1997
A prospective follow-up study of 5669 users of lansoprazole in daily practice.
    Alimentary pharmacology & therapeutics, 1997, Volume: 11, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agen

1997
Duodenal ulcer healing after 7-day treatment: a pilot study with lansoprazole, amoxicillin, and clarithromycin.
    Helicobacter, 1996, Volume: 1, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Ulcer Agents; Clarithromycin; Clinical Tr

1996
Enhancement of neutrophil infiltration in the corpus after failure of Helicobacter pylori eradication.
    Journal of clinical gastroenterology, 1997, Volume: 25 Suppl 1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Biop

1997
Effect of Helicobacter pylori infection on gastric juice pH.
    Scandinavian journal of gastroenterology, 1998, Volume: 33, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Ammonia; Amoxicillin; Anti-Ulcer Agents; Case-Control Studi

1998
Relationship between the eradication of Helicobacter pylori and the healing pattern of peptic ulcer.
    Journal of clinical gastroenterology, 1998, Volume: 27 Suppl 1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer

1998
Gastric urease activity is inversely associated with the success of treatment for Helicobacter pylori: effect of sofalcone.
    Journal of clinical gastroenterology, 1998, Volume: 27 Suppl 1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Amoxicillin; Anti-Ulcer Agents; Breath Tests;

1998
Effects of pantoprazole, a novel H+/K+-ATPase inhibitor, on duodenal ulcerogenic and healing responses in rats: a comparative study with omeprazole and lansoprazole.
    Journal of gastroenterology and hepatology, 1999, Volume: 14, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acetic Acid; Animals; Anti-Ulcer Agents; Benzimidazoles; Bi

1999
Relapse of duodenal ulcers after successful eradication of Helicobacter pylori in gastric ulcer patients.
    Journal of gastroenterology, 1999, Volume: 34 Suppl 11

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agent

1999
[Does eliminating Helicobacter pylori mean the healing of the duodenal ulcer? The results of a prospective study in Spain].
    Gastroenterologia y hepatologia, 2000, Volume: 23, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agent

2000
Evaluation of the cost-effectiveness of Helicobacter pylori eradication triple therapy vs. conventional therapy for ulcers in Japan.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:11

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clar

2001
Fine-needle aspiration biopsy of an intra-abdominal inflammatory mass secondary to a penetrating duodenal ulcer mimicking neoplasm.
    Diagnostic cytopathology, 2001, Volume: 25, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Biopsy, Needle; Clarithromycin; Diagnosis, Dif

2001
Effects of a proton pump inhibitor, AG-1749 (lansoprazole), on reflux esophagitis and experimental ulcers in rats.
    Japanese journal of pharmacology, 1991, Volume: 55, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Duodenal Ulcer; Duodenum; Esoph

1991
[AG1749: a study of its inhibition of gastric pH after morning or evening dosage].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1988, Volume: 85, Issue:12

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Depression, Chemical; Drug Administration Schedule;

1988