Page last updated: 2024-10-30

lansoprazole and Diseases of Pharynx

lansoprazole has been researched along with Diseases of Pharynx in 8 studies

Lansoprazole: A 2,2,2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS. Lansoprazole is a racemic mixture of (R)- and (S)-isomers.

Research Excerpts

ExcerptRelevanceReference
"Globus pharyngeus and dysphagia are common complaints of patients referred to ear, nose, and throat (ENT) clinics."1.38Role of flexible transnasal esophagoscopy and patient education in the management of globus pharyngeus. ( Chen, CK; Chen, TM; Cheng, CC; Fang, TJ; Hsiao, HR; Huang, HC; Kuo, YL; Lee, LA; Lee, TJ; Li, HY; Lin, W; Yeh, AR, 2012)
"In the dysphagia group, 48 of 54 patients (89%) had edema of the posterior larynx, and 42 of 54 (78%) had laryngopharyngeal sensory deficits."1.31Laryngopharyngeal sensory deficits in patients with laryngopharyngeal reflux and dysphagia. ( Aviv, JE; Close, LG; Kaplan, ST; Liu, H; Parides, M, 2000)
" Results were further analyzed to compare failure rates based on different dosage regimens."1.31Proton pump inhibitor resistance in the treatment of laryngopharyngeal reflux. ( Amin, MR; Digges, N; Johnson, P; Koufman, JA; Postma, GN, 2001)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (62.50)29.6817
2010's3 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, DY2
Jia, L2
Gu, X1
Jiang, SM2
Xie, HL1
Xu, J2
Zhou, WC1
Liu, Y1
Liu, J1
Yang, M1
Dumper, J1
Mechor, B1
Chau, J1
Allegretto, M1
Cheng, CC1
Fang, TJ1
Lee, TJ1
Lee, LA1
Chen, TM1
Chen, CK1
Yeh, AR1
Huang, HC1
Hsiao, HR1
Lin, W1
Kuo, YL1
Li, HY1
Hill, RK1
Simpson, CB1
Velazquez, R1
Larson, N1
Aviv, JE1
Liu, H1
Parides, M1
Kaplan, ST1
Close, LG1
Belafsky, PC1
Postma, GN2
Koufman, JA2
Amin, MR1
Johnson, P1
Digges, N1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized, Placebo-Controlled Assessment of Lansoprazole 30 mg Bid in the Treatment of Gastroesophageal Reflux Associated With Laryngitis[NCT00369265]Phase 418 participants (Actual)Interventional2006-08-31Terminated (stopped due to Pharmaceutical company purchased by another company and funding was terminated.)
A Prospective Evaluation of the Utility, Optimal Cutoff and Positive Predictive Value of a Pharyngeal pH Probe for Predicting Proton Pump Inhibitor Response in Treatment Naive Laryngopharyngeal Reflux[NCT01755221]80 participants (Anticipated)Interventional2012-08-31Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for lansoprazole and Diseases of Pharynx

ArticleYear
Comparison of paroxetine and amitriptyline in the treatment of refractory globus pharyngeus.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2016, Volume: 48, Issue:9

    Topics: Adult; Amitriptyline; Antidepressive Agents; Anxiety; China; Depression; Double-Blind Method; Female

2016
The effects of paroxetine and amitriptyline on the upper esophageal sphincter (UES) pressure and its natural history in globus pharyngeus.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2017, Volume: 49, Issue:7

    Topics: Adult; Amitriptyline; Antidepressive Agents; Esophageal Sphincter, Upper; Female; Humans; Lansoprazo

2017
Lansoprazole in globus pharyngeus: double-blind, randomized, placebo-controlled trial.
    Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale, 2008, Volume: 37, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Ambulatory Care; Dose-Response Relationship, Drug; D

2008

Other Studies

5 other studies available for lansoprazole and Diseases of Pharynx

ArticleYear
Role of flexible transnasal esophagoscopy and patient education in the management of globus pharyngeus.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2012, Volume: 111, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Deglutition Disorders; Esophagoscopy; Female;

2012
Pachydermia is not diagnostic of active laryngopharyngeal reflux disease.
    The Laryngoscope, 2004, Volume: 114, Issue:9

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Benzimid

2004
Laryngopharyngeal sensory deficits in patients with laryngopharyngeal reflux and dysphagia.
    The Annals of otology, rhinology, and laryngology, 2000, Volume: 109, Issue:11

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Ulcer Agents; Deglutition Disorders; Fema

2000
Laryngopharyngeal reflux symptoms improve before changes in physical findings.
    The Laryngoscope, 2001, Volume: 111, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Benzimidazoles; Female; Follow-Up Studie

2001
Laryngopharyngeal reflux symptoms improve before changes in physical findings.
    The Laryngoscope, 2001, Volume: 111, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Benzimidazoles; Female; Follow-Up Studie

2001
Laryngopharyngeal reflux symptoms improve before changes in physical findings.
    The Laryngoscope, 2001, Volume: 111, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Benzimidazoles; Female; Follow-Up Studie

2001
Laryngopharyngeal reflux symptoms improve before changes in physical findings.
    The Laryngoscope, 2001, Volume: 111, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Benzimidazoles; Female; Follow-Up Studie

2001
Proton pump inhibitor resistance in the treatment of laryngopharyngeal reflux.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2001, Volume: 125, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Aged, 80 and over; Female; Humans;

2001