lansoprazole has been researched along with Disease Models, Animal in 38 studies
Lansoprazole: A 2,2,2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS. Lansoprazole is a racemic mixture of (R)- and (S)-isomers.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here, we investigated the effects of lansoprazole on cardiac hypertrophy and heart failure, as well as the underlying mechanisms." | 7.96 | Lansoprazole alleviates pressure overload-induced cardiac hypertrophy and heart failure in mice by blocking the activation of β-catenin. ( Bin, J; Chen, L; Chen, Z; Kitakaze, M; Li, Y; Liao, W; Liao, Y; Lin, H; Wang, Q; Wang, Y; Zheng, C; Zhu, H; Zhu, Y, 2020) |
| "The aim of this study was to comparatively investigate the potential gastroprotective effect and underlying mechanisms of coptisine free base (CFB, 8-hydroxy-7, 8-dihydrocoptisine), berberine and lansoprazole against indomethacin-induced gastric ulcer in rats." | 7.88 | Protective effect of coptisine free base on indomethacin-induced gastric ulcers in rats: Characterization of potential molecular mechanisms. ( Chen, H; Lai, X; Li, C; Lin, G; Luo, C; Su, Z; Tan, L; Wang, Y; Xie, J; Zeng, H, 2018) |
| " The pharmacological activity of AFE and pure scopoletin at the same equivalent dose present in AFE was investigated in rat on gastro-esophageal inflammatory models (acid reflux esophagitis, acute gastritis induced by ethanol and serotonin, and chronic gastric ulcer induced by acetic acid); gastric biochemical parameters and gastrointestinal motility." | 7.77 | Effects of Morinda citrifolia aqueous fruit extract and its biomarker scopoletin on reflux esophagitis and gastric ulcer in rats. ( Kasiwong, S; Mahattanadul, S; Nima, S; Phdoongsombut, N; Ratanasuwon, P; Ridtitid, W, 2011) |
| "To clarify the effector sites of lansoprazole in the colonic mucosa during the formation of colitis, dextran sulfate sodium-induced colitis was induced by the oral administration of 3% aqueous solution for 3 and 7 days." | 7.73 | Lansoprazole binding to the neutrophils in dextran sulfate sodium-induced rat colitis. ( Arakawa, T; Asada, M; Atsuda, K; Hibi, N; Higuchi, K; Matsui, H; Nakamura, M; Tsuchimoto, K; Watanabe, T, 2005) |
| " Chronic administration of hydrocortisone sodium phosphate resulted in a significant delay of ulcer healing induced by acetic acid." | 5.28 | Effects of sucralfate, lansoprazole, and cimetidine on the delayed healing by hydrocortisone sodium phosphate of chronic gastric ulcers in the rat. ( Eastwood, GL; Kuwayama, H; Matsuo, Y, 1991) |
| " trimera (EOBT) against gastric ulcer lesions caused by absolute ethanol and acetic acid, respectively, and to identify the mechanism of action of this essential oil in male Wistar rats." | 4.02 | The essential oil from Baccharis trimera (Less.) DC improves gastric ulcer healing in rats through modulation of VEGF and MMP-2 activity. ( Assunção, R; Besten, MA; Bueno, G; Chavez Rico, SL; Emílio-Silva, MT; Heiden, G; Hiruma-Lima, CA; Justulin, LA; Lima Camargo, AC; Machado da Rocha, LR; Nunes, DS; Ohara, R; Périco, LL; Rodrigues, VP, 2021) |
| " Here, we investigated the effects of lansoprazole on cardiac hypertrophy and heart failure, as well as the underlying mechanisms." | 3.96 | Lansoprazole alleviates pressure overload-induced cardiac hypertrophy and heart failure in mice by blocking the activation of β-catenin. ( Bin, J; Chen, L; Chen, Z; Kitakaze, M; Li, Y; Liao, W; Liao, Y; Lin, H; Wang, Q; Wang, Y; Zheng, C; Zhu, H; Zhu, Y, 2020) |
| "The aim of this study was to comparatively investigate the potential gastroprotective effect and underlying mechanisms of coptisine free base (CFB, 8-hydroxy-7, 8-dihydrocoptisine), berberine and lansoprazole against indomethacin-induced gastric ulcer in rats." | 3.88 | Protective effect of coptisine free base on indomethacin-induced gastric ulcers in rats: Characterization of potential molecular mechanisms. ( Chen, H; Lai, X; Li, C; Lin, G; Luo, C; Su, Z; Tan, L; Wang, Y; Xie, J; Zeng, H, 2018) |
| " The aim of this work was to assess the gastroprotective effect of amino acid amides from imbricatolic acid and its 8(9)-en isomer in the ethanol/HCl-induced gastric lesions model in mice as well as to determine the cytotoxicity of the obtained compounds on the following human cell lines: normal lung fibroblasts (MRC-5), gastric adenocarcinoma (AGS), and liver hepatocellular carcinoma (Hep G2)." | 3.77 | Gastroprotective effect and cytotoxicity of labdeneamides with amino acids. ( Rodríguez, JA; Schmeda-Hirschmann, G; Theoduloz, C; Valderrama, JA, 2011) |
| " The pharmacological activity of AFE and pure scopoletin at the same equivalent dose present in AFE was investigated in rat on gastro-esophageal inflammatory models (acid reflux esophagitis, acute gastritis induced by ethanol and serotonin, and chronic gastric ulcer induced by acetic acid); gastric biochemical parameters and gastrointestinal motility." | 3.77 | Effects of Morinda citrifolia aqueous fruit extract and its biomarker scopoletin on reflux esophagitis and gastric ulcer in rats. ( Kasiwong, S; Mahattanadul, S; Nima, S; Phdoongsombut, N; Ratanasuwon, P; Ridtitid, W, 2011) |
| "To clarify the effector sites of lansoprazole in the colonic mucosa during the formation of colitis, dextran sulfate sodium-induced colitis was induced by the oral administration of 3% aqueous solution for 3 and 7 days." | 3.73 | Lansoprazole binding to the neutrophils in dextran sulfate sodium-induced rat colitis. ( Arakawa, T; Asada, M; Atsuda, K; Hibi, N; Higuchi, K; Matsui, H; Nakamura, M; Tsuchimoto, K; Watanabe, T, 2005) |
| " Minor adverse events include headache, diarrhoea, dizziness, pruritus and rash." | 2.39 | Safety of proton pump inhibitors--an overview. ( Arnold, R, 1994) |
| "Colitis was induced with less C." | 1.48 | Proton Pump Inhibitors Increase the Susceptibility of Mice to Oral Infection with Enteropathogenic Bacteria. ( Adachi, S; Azuma, T; Fukuda, S; Hoshi, N; Inoue, J; Ishida, T; Kong, L; Ku, Y; Ooi, M; Otsuka, T; Tsukimi, T; Watanabe, D; Yamairi, H; Yasutomi, E; Yoshida, M, 2018) |
| "A key event in the pathogenesis of Alzheimer's disease (AD) is the accumulation of amyloid-β (Aβ) species in the brain, derived from the sequential cleavage of the amyloid precursor protein (APP) by β- and γ-secretases." | 1.39 | The proton-pump inhibitor lansoprazole enhances amyloid beta production. ( Alcalde, V; Aloy, P; Badiola, N; Coma, M; Lleó, A; Multhaup, G; Münter, LM; Pujol, A; Soler-López, M, 2013) |
| "Omeprazole treatment did not result in mucosal injury or inflammation; however, there were marked shifts in numbers and types of enteric bacteria, including a significant reduction (∼80%) of jejunal Actinobacteria and Bifidobacteria spp." | 1.37 | Proton pump inhibitors exacerbate NSAID-induced small intestinal injury by inducing dysbiosis. ( Bercik, P; Bolla, M; Collins, SM; de Palma, G; Denou, E; Jury, J; McKnight, W; Ongini, E; Syer, S; Verdu, E; Vong, L; Wallace, JL, 2011) |
| "Treatment with lansoprazole resulted in up to ninefold dose-dependent increases in endogenous gastrin levels (p < 0." | 1.36 | Treatment with a proton pump inhibitor improves glycaemic control in Psammomys obesus, a model of type 2 diabetes. ( Bödvarsdóttir, TB; Gotfredsen, CF; Hove, KD; Karlsen, AE; Petersen, JS; Pridal, L; Vaag, A, 2010) |
| "Stress gastric ulcer is a serious complication, but the mechanism involved is not fully clarified." | 1.33 | Endoplasmic reticulum stress response is involved in the pathogenesis of stress induced gastric lesions in rats. ( Chen, L; Geng, B; Ke, Y; Lou, LX; Pan, CS; Qi, YF; Tang, CS; Wang, X; Yu, F; Zhang, J, 2006) |
| " Chronic administration of hydrocortisone sodium phosphate resulted in a significant delay of ulcer healing induced by acetic acid." | 1.28 | Effects of sucralfate, lansoprazole, and cimetidine on the delayed healing by hydrocortisone sodium phosphate of chronic gastric ulcers in the rat. ( Eastwood, GL; Kuwayama, H; Matsuo, Y, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (7.89) | 18.2507 |
| 2000's | 11 (28.95) | 29.6817 |
| 2010's | 16 (42.11) | 24.3611 |
| 2020's | 8 (21.05) | 2.80 |
| Authors | Studies |
|---|---|
| Sepúlveda, B | 1 |
| Quispe, C | 1 |
| Simirgiotis, M | 1 |
| García-Beltrán, O | 1 |
| Areche, C | 1 |
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 1 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Bae, HJ | 2 |
| Kim, JY | 1 |
| Park, K | 1 |
| Yang, X | 1 |
| Jung, SY | 1 |
| Park, SJ | 1 |
| Kim, DH | 1 |
| Shin, CY | 1 |
| Ryu, JH | 1 |
| Kosukegawa, I | 1 |
| Okazaki, S | 1 |
| Yamamoto, M | 1 |
| Nagoya, S | 1 |
| Suzuki, C | 1 |
| Shimizu, J | 1 |
| Takahashi, H | 1 |
| Yamashita, T | 1 |
| Gamil, NM | 1 |
| Abd El Fattah, MA | 1 |
| Ahmed, MAE | 1 |
| Maklad, YA | 1 |
| Gamal El Din, AA | 1 |
| Eid, NI | 1 |
| Satoh, H | 1 |
| Akiba, Y | 1 |
| Urushidani, T | 1 |
| Bueno, G | 1 |
| Chavez Rico, SL | 1 |
| Périco, LL | 1 |
| Ohara, R | 1 |
| Rodrigues, VP | 1 |
| Emílio-Silva, MT | 1 |
| Assunção, R | 1 |
| Machado da Rocha, LR | 1 |
| Nunes, DS | 1 |
| Besten, MA | 1 |
| Heiden, G | 1 |
| Lima Camargo, AC | 1 |
| Justulin, LA | 1 |
| Hiruma-Lima, CA | 3 |
| Ye, L | 1 |
| Pang, W | 1 |
| Huang, Y | 1 |
| Wu, H | 1 |
| Huang, X | 1 |
| Liu, J | 1 |
| Wang, S | 1 |
| Yang, C | 1 |
| Pan, Q | 1 |
| Liu, H | 1 |
| Luo, C | 1 |
| Chen, H | 1 |
| Wang, Y | 2 |
| Lin, G | 1 |
| Li, C | 1 |
| Tan, L | 1 |
| Su, Z | 1 |
| Lai, X | 1 |
| Xie, J | 1 |
| Zeng, H | 1 |
| Yasutomi, E | 1 |
| Hoshi, N | 1 |
| Adachi, S | 1 |
| Otsuka, T | 1 |
| Kong, L | 1 |
| Ku, Y | 1 |
| Yamairi, H | 1 |
| Inoue, J | 1 |
| Ishida, T | 1 |
| Watanabe, D | 1 |
| Ooi, M | 1 |
| Yoshida, M | 1 |
| Tsukimi, T | 1 |
| Fukuda, S | 1 |
| Azuma, T | 1 |
| Nishi, T | 1 |
| Yamamoto, Y | 1 |
| Yamagishi, N | 1 |
| Iguchi, M | 1 |
| Tamai, H | 1 |
| Ito, T | 1 |
| Tsuruo, Y | 1 |
| Ichinose, M | 1 |
| Kitano, M | 1 |
| Ueyama, T | 1 |
| Lin, H | 1 |
| Li, Y | 1 |
| Zhu, H | 1 |
| Wang, Q | 1 |
| Chen, Z | 1 |
| Chen, L | 2 |
| Zhu, Y | 1 |
| Zheng, C | 1 |
| Liao, W | 1 |
| Bin, J | 1 |
| Kitakaze, M | 1 |
| Liao, Y | 1 |
| Nakatake, R | 1 |
| Hishikawa, H | 1 |
| Kotsuka, M | 1 |
| Ishizaki, M | 1 |
| Matsui, K | 1 |
| Nishizawa, M | 1 |
| Yoshizawa, K | 1 |
| Kaibori, M | 1 |
| Okumura, T | 1 |
| Badiola, N | 1 |
| Alcalde, V | 1 |
| Pujol, A | 1 |
| Münter, LM | 1 |
| Multhaup, G | 1 |
| Lleó, A | 1 |
| Coma, M | 1 |
| Soler-López, M | 1 |
| Aloy, P | 1 |
| Ghebremariam, YT | 1 |
| LePendu, P | 1 |
| Lee, JC | 1 |
| Erlanson, DA | 1 |
| Slaviero, A | 1 |
| Shah, NH | 1 |
| Leiper, J | 1 |
| Cooke, JP | 1 |
| Kobayashi, S | 1 |
| Nakajima, N | 1 |
| Ito, Y | 1 |
| Moriyama, M | 1 |
| Bödvarsdóttir, TB | 1 |
| Hove, KD | 1 |
| Gotfredsen, CF | 1 |
| Pridal, L | 1 |
| Vaag, A | 1 |
| Karlsen, AE | 1 |
| Petersen, JS | 1 |
| Schmeda-Hirschmann, G | 3 |
| Rodríguez, JA | 3 |
| Theoduloz, C | 3 |
| Valderrama, JA | 1 |
| Fornai, M | 2 |
| Colucci, R | 2 |
| Antonioli, L | 2 |
| Awwad, O | 1 |
| Ugolini, C | 1 |
| Tuccori, M | 1 |
| Fulceri, F | 1 |
| Natale, G | 2 |
| Basolo, F | 1 |
| Blandizzi, C | 2 |
| Mahattanadul, S | 1 |
| Ridtitid, W | 1 |
| Nima, S | 1 |
| Phdoongsombut, N | 1 |
| Ratanasuwon, P | 1 |
| Kasiwong, S | 1 |
| Pertino, MW | 1 |
| Kaur, S | 1 |
| Vaishnavi, C | 1 |
| Prasad, KK | 1 |
| Ray, P | 1 |
| Kochhar, R | 1 |
| Wallace, JL | 1 |
| Syer, S | 1 |
| Denou, E | 1 |
| de Palma, G | 1 |
| Vong, L | 1 |
| McKnight, W | 1 |
| Jury, J | 1 |
| Bolla, M | 1 |
| Bercik, P | 1 |
| Collins, SM | 1 |
| Verdu, E | 1 |
| Ongini, E | 1 |
| Bagcivan, I | 1 |
| Gökçe, G | 1 |
| Ayan, S | 1 |
| Yildirim, S | 1 |
| Saraç, B | 1 |
| Kiliçarslan, H | 1 |
| Sarioglu, Y | 1 |
| Batista, LM | 1 |
| de Almeida, AB | 2 |
| de Pietro Magri, L | 1 |
| Toma, W | 3 |
| Calvo, TR | 1 |
| Vilegas, W | 1 |
| Souza Brito, AR | 2 |
| Sánchez, M | 1 |
| Yáñez, T | 1 |
| Razmilic, I | 1 |
| Lubrano, V | 1 |
| Vassalle, C | 1 |
| Lazzeri, G | 1 |
| Del Tacca, M | 1 |
| Nakamura, M | 1 |
| Asada, M | 1 |
| Atsuda, K | 1 |
| Matsui, H | 1 |
| Watanabe, T | 1 |
| Higuchi, K | 1 |
| Arakawa, T | 1 |
| Hibi, N | 1 |
| Tsuchimoto, K | 1 |
| Lou, LX | 1 |
| Geng, B | 1 |
| Yu, F | 1 |
| Zhang, J | 1 |
| Pan, CS | 1 |
| Qi, YF | 1 |
| Ke, Y | 1 |
| Wang, X | 1 |
| Tang, CS | 1 |
| Romero-Gallo, J | 1 |
| Harris, EJ | 1 |
| Krishna, U | 1 |
| Washington, MK | 1 |
| Perez-Perez, GI | 1 |
| Peek, RM | 1 |
| Arnold, R | 1 |
| Omura, N | 1 |
| Kashiwagi, H | 1 |
| Chen, G | 1 |
| Suzuki, Y | 1 |
| Yano, F | 1 |
| Aoki, T | 1 |
| Gracioso, JD | 1 |
| de Paula, AC | 1 |
| Brasil, DD | 1 |
| Muller, AH | 2 |
| Brito, AR | 1 |
| Bilic, I | 1 |
| Zoricic, I | 1 |
| Anic, T | 1 |
| Separovic, J | 1 |
| Stancic-Rokotov, D | 1 |
| Mikus, D | 1 |
| Buljat, G | 1 |
| Ivankovic, D | 1 |
| Aralica, G | 1 |
| Prkacin, I | 1 |
| Perovic, D | 1 |
| Mise, S | 1 |
| Rotkvic, I | 1 |
| Petek, M | 1 |
| Rucman, R | 1 |
| Seiwerth, S | 1 |
| Sikiric, P | 1 |
| Gracioso, JS | 1 |
| Almeida, AB | 1 |
| Paula, AC | 1 |
| Brasil, DS | 1 |
| McDonald, JM | 1 |
| Longnecker, DS | 1 |
| Bell, RH | 1 |
| Kuwayama, H | 1 |
| Matsuo, Y | 1 |
| Eastwood, GL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Impact of Pantoprazole on 24-H Glycemic Control and on Post-prandial Glucose Excursion Inpatients With Type 2 Diabetes[NCT02345239] | Phase 3 | 14 participants (Anticipated) | Interventional | 2015-02-28 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for lansoprazole and Disease Models, Animal
| Article | Year |
|---|---|
Safety of proton pump inhibitors--an overview.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Benzimidazoles; Cytochrome P-450 Enzyme System; Di | 1994 |
37 other studies available for lansoprazole and Disease Models, Animal
| Article | Year |
|---|---|
Gastroprotective effects of new diterpenoid derivatives from Azorella cuatrecasasii Mathias & Constance obtained using a β-cyclodextrin complex with microbial and chemical transformations.
Topics: Alcohols; Animals; Anti-Ulcer Agents; Apiaceae; beta-Cyclodextrins; Disease Models, Animal; Diterpen | 2016 |
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
The effect of lansoprazole on MK-801-induced schizophrenia-like behaviors in mice.
Topics: Animals; Disease Models, Animal; Dizocilpine Maleate; Interleukin-6; Lansoprazole; Mice; Proton Pump | 2023 |
The proton pump inhibitor, lansoprazole, prevents the development of non-traumatic osteonecrosis of the femoral head: an experimental and prospective clinical trial.
Topics: Adrenal Cortex Hormones; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Female; Femur He | 2020 |
Lansoprazole enhances the antidiabetic effect of dapagliflozin in fortified diet-fed streptozotocin-treated diabetic rats.
Topics: Animals; Benzhydryl Compounds; Blood Glucose; Body Weight; Cholesterol; Diabetes Mellitus, Experimen | 2020 |
Proton Pump Inhibitors Prevent Gastric Antral Ulcers Induced by NSAIDs via Activation of Capsaicin-Sensitive Afferent Nerves in Mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Disease Models, Animal; Gastric Emptyin | 2020 |
The essential oil from Baccharis trimera (Less.) DC improves gastric ulcer healing in rats through modulation of VEGF and MMP-2 activity.
Topics: Acetic Acid; Animals; Anti-Ulcer Agents; Baccharis; Brazil; Caspases; Cyclooxygenase 1; Cyclooxygena | 2021 |
Lansoprazole promotes cisplatin-induced acute kidney injury via enhancing tubular necroptosis.
Topics: Acute Kidney Injury; Animals; Antineoplastic Agents; Apoptosis; Cisplatin; Disease Models, Animal; D | 2021 |
Protective effect of coptisine free base on indomethacin-induced gastric ulcers in rats: Characterization of potential molecular mechanisms.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Berberine; Cyclooxygenase 1; Cyclooxygenase 2; Dise | 2018 |
Proton Pump Inhibitors Increase the Susceptibility of Mice to Oral Infection with Enteropathogenic Bacteria.
Topics: Animals; Citrobacter rodentium; Colitis; Disease Models, Animal; Enterobacteriaceae Infections; Lans | 2018 |
Lansoprazole prevents the progression of liver fibrosis in non-alcoholic steatohepatitis model rats.
Topics: Animals; Aspartate Aminotransferases; Diet; Disease Models, Animal; Disease Progression; Heme Oxygen | 2018 |
Lansoprazole alleviates pressure overload-induced cardiac hypertrophy and heart failure in mice by blocking the activation of β-catenin.
Topics: Animals; Aorta; beta Catenin; Cell Proliferation; Cells, Cultured; Constriction; Disease Models, Ani | 2020 |
The Proton Pump Inhibitor Lansoprazole Has Hepatoprotective Effects in In Vitro and In Vivo Rat Models of Acute Liver Injury.
Topics: Animals; Cells, Cultured; Disease Models, Animal; Hepatocytes; Lansoprazole; Liver; Liver Failure, A | 2019 |
The proton-pump inhibitor lansoprazole enhances amyloid beta production.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Alzheimer Disease; Amyloid beta-Peptides; Animals; CHO Cell | 2013 |
Unexpected effect of proton pump inhibitors: elevation of the cardiovascular risk factor asymmetric dimethylarginine.
Topics: Amidohydrolases; Animals; Arginine; Biomarkers; Cardiovascular Diseases; Cells, Cultured; Disease Mo | 2013 |
Effects of lansoprazole on the expression of VEGF and cellular proliferation in a rat model of acetic acid-induced gastric ulcer.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acetic Acid; Animals; Anti-Ulcer Agents; Cell Cycle; Cell P | 2010 |
Treatment with a proton pump inhibitor improves glycaemic control in Psammomys obesus, a model of type 2 diabetes.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Analysis of Variance; Animals; Blood Glucose; Diabetes Mell | 2010 |
Gastroprotective effect and cytotoxicity of labdeneamides with amino acids.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenocarcinoma; Amides; Amino Acids; Animals; Anti-Ulcer Ag | 2011 |
Effects of esomeprazole on healing of nonsteroidal anti-inflammatory drug (NSAID)-induced gastric ulcers in the presence of a continued NSAID treatment: Characterization of molecular mechanisms.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulce | 2011 |
Effects of Morinda citrifolia aqueous fruit extract and its biomarker scopoletin on reflux esophagitis and gastric ulcer in rats.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acetic Acid; Animals; Biomarkers; Cisapride; Disease Models | 2011 |
Gastroprotective effect and cytotoxicity of carnosic acid derivatives.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Abietanes; Animals; Anti-Ulcer Agents; Antioxidants; Cell L | 2011 |
Effect of Lactobacillus acidophilus & epidermal growth factor on experimentally induced Clostridium difficile infection.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Ampicillin; Animals; Cecum; Clostridioides difficile; Colon | 2011 |
Proton pump inhibitors exacerbate NSAID-induced small intestinal injury by inducing dysbiosis.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Actinobacteria; Animals; Anti-Inflammatory Agents, Non-Ster | 2011 |
Hydrogen-potassium ATPase inhibitors induce relaxation on rabbit prostatic strips in vitro.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Disease Models, Animal; Enzyme Inhibitors; H(+)-K( | 2002 |
Gastric antiulcer activity of Syngonanthus arthrotrichus SILVEIRA.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Bethanechol; Cimetidine; Diseas | 2004 |
Gastroprotective activity of a new semi-synthetic solidagenone derivative in mice.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Animals; Anti-Ulcer Agents; Cell Line | 2005 |
Lansoprazole prevents experimental gastric injury induced by non-steroidal anti-inflammatory drugs through a reduction of mucosal oxidative damage.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulce | 2005 |
Lansoprazole binding to the neutrophils in dextran sulfate sodium-induced rat colitis.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Infective Agents; Apoptosis; Autoradiography; | 2005 |
Endoplasmic reticulum stress response is involved in the pathogenesis of stress induced gastric lesions in rats.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Apoptosis; Caspase 12; Caspases; Disease Models, A | 2006 |
Effect of Helicobacter pylori eradication on gastric carcinogenesis.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenocarcinoma; Amoxicillin; Animals; Animals, Outbred Stra | 2008 |
Establishment of surgically induced chronic acid reflux esophagitis in rats.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Disease Models, Animal; Enzyme | 1999 |
Evaluation of the gastroprotective activity of cordatin, a diterpene isolated from Aparisthmium cordatum (Euphorbiaceae).
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Disease Models, Animal; Diterpe | 2000 |
Haloperidol-stomach lesions attenuation by pentadecapeptide BPC 157, omeprazole, bromocriptine, but not atropine, lansoprazole, pantoprazole, ranitidine, cimetidine and misoprostol in mice.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Atropine; Benzimidazoles; Bromo | 2001 |
Gastroprotective effect of aparisthman, a diterpene isolated from Aparisthmium cordatum, on experimental gastric ulcer models in rats and mice.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulce | 2001 |
Effect of hypergastrinemia on pancreatic carcinogenesis.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenoma; Animals; Anti-Ulcer Agents; Azaserine; Carcinoma i | 2002 |
Effects of sucralfate, lansoprazole, and cimetidine on the delayed healing by hydrocortisone sodium phosphate of chronic gastric ulcers in the rat.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Cimetidi | 1991 |