lansoprazole has been researched along with Diabetic Nephropathies in 2 studies
Lansoprazole: A 2,2,2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS. Lansoprazole is a racemic mixture of (R)- and (S)-isomers.
Diabetic Nephropathies: KIDNEY injuries associated with diabetes mellitus and affecting KIDNEY GLOMERULUS; ARTERIOLES; KIDNEY TUBULES; and the interstitium. Clinical signs include persistent PROTEINURIA, from microalbuminuria progressing to ALBUMINURIA of greater than 300 mg/24 h, leading to reduced GLOMERULAR FILTRATION RATE and END-STAGE RENAL DISEASE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Diabetic nephropathy was induced with a single injection of streptozotocin (STZ, 45 mg/kg, i." | 1.43 | Renoprotective effect of lansoprazole in streptozotocin-induced diabetic nephropathy in wistar rats. ( Aggarwal, N; Jain, UK; Kaur, J; Kaur, R; Sodhi, RK, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mostafa, DK | 1 |
| Khedr, MM | 1 |
| Barakat, MK | 1 |
| Abdellatif, AA | 1 |
| Elsharkawy, AM | 1 |
| Kaur, R | 1 |
| Sodhi, RK | 1 |
| Aggarwal, N | 1 |
| Kaur, J | 1 |
| Jain, UK | 1 |
2 other studies available for lansoprazole and Diabetic Nephropathies
| Article | Year |
|---|---|
Autophagy blockade mechanistically links proton pump inhibitors to worsened diabetic nephropathy and aborts the renoprotection of metformin/enalapril.
Topics: Albuminuria; Animals; Autophagy; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Diet, High | 2021 |
Renoprotective effect of lansoprazole in streptozotocin-induced diabetic nephropathy in wistar rats.
Topics: Animals; Blood Glucose; Blood Urea Nitrogen; Brain; Cholesterol; Creatinine; Diabetes Mellitus, Expe | 2016 |