lansoprazole has been researched along with Critical Illness in 3 studies
Lansoprazole: A 2,2,2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS. Lansoprazole is a racemic mixture of (R)- and (S)-isomers.
Critical Illness: A disease or state in which death is possible or imminent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "While proton pump inhibitors are frequently administered in the intensive care unit, the pharmacodynamic response of acid suppression between the enteral and intravenous (IV) route is unknown." | 2.73 | Comparison of the enteral and intravenous lansoprazole pharmacodynamic responses in critically ill patients. ( Devlin, JW; Olsen, KM, 2008) |
| "Lansoprazole 30 mg was administered once daily with water through a nasogastric tube for 2 days." | 2.69 | Nasogastric lansoprazole is effective in suppressing gastric acid secretion in critically ill patients. ( Chang, CS; Chen, GH; Ko, CW; Poon, SK; Tsai, WL; Yeh, HZ; Yu, HK, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Olsen, KM | 1 |
| Devlin, JW | 1 |
| Brophy, GM | 1 |
| Brackbill, ML | 1 |
| Bidwell, KL | 1 |
| Brophy, DF | 1 |
| Tsai, WL | 1 |
| Poon, SK | 1 |
| Yu, HK | 1 |
| Chang, CS | 1 |
| Yeh, HZ | 1 |
| Ko, CW | 1 |
| Chen, GH | 1 |
3 trials available for lansoprazole and Critical Illness
| Article | Year |
|---|---|
Comparison of the enteral and intravenous lansoprazole pharmacodynamic responses in critically ill patients.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Critical Illness; Drug Administration Ro | 2008 |
Prospective, randomized comparison of lansoprazole suspension, and intermittent intravenous famotidine on gastric pH and acid production in critically ill neurosurgical patients.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Critical Illness; Famotidine; Fem | 2010 |
Nasogastric lansoprazole is effective in suppressing gastric acid secretion in critically ill patients.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Aged, 80 and over; Anti-Ulcer Agents; Critical Illnes | 2000 |