Page last updated: 2024-10-30

lansoprazole and Cough

lansoprazole has been researched along with Cough in 10 studies

Lansoprazole: A 2,2,2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS. Lansoprazole is a racemic mixture of (R)- and (S)-isomers.

Cough: A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs.

Research Excerpts

ExcerptRelevanceReference
"Out of 45 patients referred for unexplained chronic persistent cough, 36 had at least one of the GI investigations (endoscopy, 24-h esophageal pH-metry and a 4-week trial of proton pump inhibitor (PPI) therapy) positive and were randomly assigned to receive either 30 mg lansoprazole o."9.12Proton pump inhibitor treatment of patients with gastroesophageal reflux-related chronic cough: a comparison between two different daily doses of lansoprazole. ( Baldi, F; Cappiello, R; Cavoli, C; Ghersi, S; Roda, E; Torresan, F, 2006)
"The prospective, open-label, randomized study aims to compare the efficacy of lansoprazole, a fast orally disintegrating proton pump inhibitor (PPI), and dexlansoprazole, a dual delayed release PPI, in patients with atypical symptoms of gastroesophageal reflux disease (GERD)."5.34Comparison of the efficiency of two different proton pump inhibitor formula in treatment of patients with atypical gastroesophageal reflux disease: a prospective randomized study. ( Chang, TE; Hou, MC; Huang, YH; Lee, FY; Lin, XH; Luo, JC; Ting, PH, 2020)
"Out of 45 patients referred for unexplained chronic persistent cough, 36 had at least one of the GI investigations (endoscopy, 24-h esophageal pH-metry and a 4-week trial of proton pump inhibitor (PPI) therapy) positive and were randomly assigned to receive either 30 mg lansoprazole o."5.12Proton pump inhibitor treatment of patients with gastroesophageal reflux-related chronic cough: a comparison between two different daily doses of lansoprazole. ( Baldi, F; Cappiello, R; Cavoli, C; Ghersi, S; Roda, E; Torresan, F, 2006)
"The causes of syncope are diverse and may manifest in disorders of different organ systems in the body."1.35Cough syncope induced by gastroesophageal reflux disease. ( Iida, H; Kanazawa, Y; Kino, N; Kusuyama, T; Shimodozono, S, 2009)
"Chronic cough is defined as that which is persisting at least for trhee weeks without an evident cause."1.34[Otorhinolaringologyc approach of the chronic cough. Clinical case]. ( García de Hombre, AM, 2007)
"Cough was significantly less severe in NEE adolescents than in younger children."1.33Presenting symptoms of nonerosive and erosive esophagitis in pediatric patients. ( Amer, F; Chiu, YL; Gupta, SK; Hassall, E; Heyman, MB, 2006)
"The cough was eliminated or markedly improved in 38 patients (86%) after 4 weeks and by 8 weeks in the remaining 6 patients."1.32Chronic cough and gastroesophageal reflux disease: experience with specific therapy for diagnosis and treatment. ( Kallay, MC; Poe, RH, 2003)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (70.00)29.6817
2010's1 (10.00)24.3611
2020's2 (20.00)2.80

Authors

AuthorsStudies
Saul, H1
Gursul, D1
Kwint, J1
O'Hara, J1
Lin, XH1
Luo, JC1
Ting, PH1
Chang, TE1
Huang, YH1
Hou, MC1
Lee, FY1
Kusuyama, T1
Iida, H1
Kino, N1
Shimodozono, S1
Kanazawa, Y1
Garza, JM1
Nylund, CM1
Kaul, A1
Poe, RH1
Kallay, MC1
Sawabata, N1
Maeda, H1
Takeda, S1
Inoue, M1
Koma, M1
Tokunaga, T1
Matsuda, H1
Baldi, F1
Cappiello, R1
Cavoli, C1
Ghersi, S1
Torresan, F1
Roda, E1
Silvers, WS1
Levine, JS1
Poole, JA1
Naar, E1
Weber, RW1
Gupta, SK1
Hassall, E1
Chiu, YL1
Amer, F1
Heyman, MB1
García de Hombre, AM1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Clinical Application of Vagus Nerve Preservation in Minimally Invasive Surgery for Early Lung Cancer[NCT04125979]120 participants (Anticipated)Interventional2019-01-01Recruiting
Prospective Randomized Controlled Study on the Effects of Vagus Nerve Pulmonary Branch Preservation During Video-assisted Thoracic Surgery Lobectomy in Non-small Cell Lung Cancer: Can it Decrease Postoperative Cough and Pulmonary Complications[NCT04923412]214 participants (Anticipated)Interventional2021-07-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for lansoprazole and Cough

ArticleYear
Comparison of the efficiency of two different proton pump inhibitor formula in treatment of patients with atypical gastroesophageal reflux disease: a prospective randomized study.
    Journal of gastroenterology and hepatology, 2020, Volume: 35, Issue:12

    Topics: Aged; Cough; Dexlansoprazole; Dyslipidemias; Esophagitis; Female; Gastroesophageal Reflux; Globus Se

2020
Proton pump inhibitor treatment of patients with gastroesophageal reflux-related chronic cough: a comparison between two different daily doses of lansoprazole.
    World journal of gastroenterology, 2006, Jan-07, Volume: 12, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Ulcer Agents; Chronic Disease; Cough; Enz

2006

Other Studies

8 other studies available for lansoprazole and Cough

ArticleYear
Proton pump inhibitors should not be used to treat persistent throat symptoms.
    BMJ (Clinical research ed.), 2022, 03-17, Volume: 376

    Topics: Cough; Humans; Lansoprazole; Pharyngitis; Practice Patterns, Physicians'; Proton Pump Inhibitors

2022
Cough syncope induced by gastroesophageal reflux disease.
    Journal of cardiology, 2009, Volume: 54, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Bradycardia; Cough; Gastroesophageal Reflux; Humans; Lansop

2009
Time to stop blaming gastroesophageal reflux.
    Clinical pediatrics, 2011, Volume: 50, Issue:12

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Cough; Diagnosis, Differential; Electric Impedance; Enzyme

2011
Chronic cough and gastroesophageal reflux disease: experience with specific therapy for diagnosis and treatment.
    Chest, 2003, Volume: 123, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Chronic Disease; Cisapride;

2003
Persistent cough following pulmonary resection: observational and empiric study of possible causes.
    The Annals of thoracic surgery, 2005, Volume: 79, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Benzamides; Carcinoma, Non-Small-Cell Lung; Chronic D

2005
Persistent cough following pulmonary resection: observational and empiric study of possible causes.
    The Annals of thoracic surgery, 2005, Volume: 79, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Benzamides; Carcinoma, Non-Small-Cell Lung; Chronic D

2005
Persistent cough following pulmonary resection: observational and empiric study of possible causes.
    The Annals of thoracic surgery, 2005, Volume: 79, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Benzamides; Carcinoma, Non-Small-Cell Lung; Chronic D

2005
Persistent cough following pulmonary resection: observational and empiric study of possible causes.
    The Annals of thoracic surgery, 2005, Volume: 79, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Benzamides; Carcinoma, Non-Small-Cell Lung; Chronic D

2005
Inlet patch of gastric mucosa in upper esophagus causing chronic cough and vocal cord dysfunction.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2006, Volume: 96, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Androstadienes; Anti-Allergic Agents; Cough; Endoscopy, Gas

2006
Presenting symptoms of nonerosive and erosive esophagitis in pediatric patients.
    Digestive diseases and sciences, 2006, Volume: 51, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Abdominal Pain; Adolescent; Anorexia; Anti-Ulcer Agents; Ch

2006
[Otorhinolaringologyc approach of the chronic cough. Clinical case].
    Anales otorrinolaringologicos ibero-americanos, 2007, Volume: 34, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Antitussive Agents; Chronic Disease; Cou

2007