lansoprazole has been researched along with Chest Pain in 6 studies
Lansoprazole: A 2,2,2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS. Lansoprazole is a racemic mixture of (R)- and (S)-isomers.
Chest Pain: Pressure, burning, or numbness in the chest.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Double-blind placebo-controlled crossover study investigating effect of lansoprazole on chest pain; 125 patients with angiographically proven coronary artery disease enrolled with at least one weekly episode of nocturnal/rest pain, randomized to lansoprazole 30 mg daily or placebo with crossover after 4 weeks." | 9.14 | Clinical trial: chest pain caused by presumed gastro-oesophageal reflux in coronary artery disease - controlled study of lansoprazole vs. placebo. ( Bankart, MJ; de Caestecker, JS; Gershlick, AH; Talwar, V; Wurm, P, 2010) |
| "To determine the clinical value of an empirical trial of high-dose lansoprazole in detecting patients with gastro-oesophageal reflux disease-related non-cardiac chest pain." | 9.11 | The effect of an empirical trial of high-dose lansoprazole on symptom response of patients with non-cardiac chest pain--a randomized, double-blind, placebo-controlled, crossover trial. ( Bautista, J; Briseno, M; Cui, H; Fass, R; Fullerton, H, 2004) |
| "Treatment with lansoprazole is a useful test in diagnosing endoscopy-negative gastro-oesophageal reflux disease in Chinese patients with non-cardiac chest pain." | 9.10 | Symptomatic response to lansoprazole predicts abnormal acid reflux in endoscopy-negative patients with non-cardiac chest pain. ( Chan, CK; Chen, WH; Hu, WH; Hui, WM; Lai, KC; Lam, SK; Lau, CP; Wong, BC; Wong, NY; Wong, WM; Xia, HH, 2003) |
| "Double-blind placebo-controlled crossover study investigating effect of lansoprazole on chest pain; 125 patients with angiographically proven coronary artery disease enrolled with at least one weekly episode of nocturnal/rest pain, randomized to lansoprazole 30 mg daily or placebo with crossover after 4 weeks." | 5.14 | Clinical trial: chest pain caused by presumed gastro-oesophageal reflux in coronary artery disease - controlled study of lansoprazole vs. placebo. ( Bankart, MJ; de Caestecker, JS; Gershlick, AH; Talwar, V; Wurm, P, 2010) |
| "To determine the clinical value of an empirical trial of high-dose lansoprazole in detecting patients with gastro-oesophageal reflux disease-related non-cardiac chest pain." | 5.11 | The effect of an empirical trial of high-dose lansoprazole on symptom response of patients with non-cardiac chest pain--a randomized, double-blind, placebo-controlled, crossover trial. ( Bautista, J; Briseno, M; Cui, H; Fass, R; Fullerton, H, 2004) |
| "Treatment with lansoprazole is a useful test in diagnosing endoscopy-negative gastro-oesophageal reflux disease in Chinese patients with non-cardiac chest pain." | 5.10 | Symptomatic response to lansoprazole predicts abnormal acid reflux in endoscopy-negative patients with non-cardiac chest pain. ( Chan, CK; Chen, WH; Hu, WH; Hui, WM; Lai, KC; Lam, SK; Lau, CP; Wong, BC; Wong, NY; Wong, WM; Xia, HH, 2003) |
| "We aimed to examine the proportion of gastroesophageal reflux disease (GERD) in young patients with NCCP compared to the average-aged NCCP patients and to evaluate their symptomatic characteristics and the clinical efficacy of a 2-week proton pump inhibitor (PPI) trial." | 2.77 | Clinically distinct characteristics in patients younger than 40 years old with non-cardiac chest pain. ( Hong, SN; Kim, JH; Kim, SI; Ko, SY; Lee, JH; Lee, KJ; Lee, SY; Park, HS; Shim, CS; Sung, IK, 2012) |
| "Unexplained chest pain is potentially attributable to gastro-oesophageal reflux disease (GORD) or oesophageal motility disorders." | 2.47 | Response of unexplained chest pain to proton pump inhibitor treatment in patients with and without objective evidence of gastro-oesophageal reflux disease. ( Howden, CW; Hughes, N; Kahrilas, PJ, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Talwar, V | 1 |
| Wurm, P | 1 |
| Bankart, MJ | 1 |
| Gershlick, AH | 1 |
| de Caestecker, JS | 1 |
| Kahrilas, PJ | 1 |
| Hughes, N | 1 |
| Howden, CW | 1 |
| Ko, SY | 1 |
| Kim, SI | 1 |
| Kim, JH | 1 |
| Lee, JH | 1 |
| Lee, KJ | 1 |
| Hong, SN | 1 |
| Lee, SY | 1 |
| Sung, IK | 1 |
| Park, HS | 1 |
| Shim, CS | 1 |
| Xia, HH | 1 |
| Lai, KC | 1 |
| Lam, SK | 1 |
| Hu, WH | 1 |
| Wong, NY | 1 |
| Hui, WM | 1 |
| Lau, CP | 1 |
| Chen, WH | 1 |
| Chan, CK | 1 |
| Wong, WM | 1 |
| Wong, BC | 1 |
| Borjesson, M | 1 |
| Rolny, P | 1 |
| Mannheimer, C | 1 |
| Pilhall, M | 1 |
| Bautista, J | 1 |
| Fullerton, H | 1 |
| Briseno, M | 1 |
| Cui, H | 1 |
| Fass, R | 1 |
1 review available for lansoprazole and Chest Pain
| Article | Year |
|---|---|
Response of unexplained chest pain to proton pump inhibitor treatment in patients with and without objective evidence of gastro-oesophageal reflux disease.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Chest Pain; Esophagus; Gastroesophageal Reflux; Heartburn; | 2011 |
5 trials available for lansoprazole and Chest Pain
| Article | Year |
|---|---|
Clinical trial: chest pain caused by presumed gastro-oesophageal reflux in coronary artery disease - controlled study of lansoprazole vs. placebo.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Chest Pa | 2010 |
Clinically distinct characteristics in patients younger than 40 years old with non-cardiac chest pain.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Age Factors; Chest Pain; Chi-Square Distribution; En | 2012 |
Symptomatic response to lansoprazole predicts abnormal acid reflux in endoscopy-negative patients with non-cardiac chest pain.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Ulcer Agents; Chest Pain; Female; Gastroe | 2003 |
Nutcracker oesophagus: a double-blind, placebo-controlled, cross-over study of the effects of lansoprazole.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Antacids; Anti-Ulcer Agents | 2003 |
The effect of an empirical trial of high-dose lansoprazole on symptom response of patients with non-cardiac chest pain--a randomized, double-blind, placebo-controlled, crossover trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Chest Pa | 2004 |