Page last updated: 2024-10-30

lansoprazole and Autoimmune Thrombocytopenia

lansoprazole has been researched along with Autoimmune Thrombocytopenia in 17 studies

Lansoprazole: A 2,2,2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS. Lansoprazole is a racemic mixture of (R)- and (S)-isomers.

Research Excerpts

ExcerptRelevanceReference
" Helicobacter pylori-infected patients with gastritis and gastric ulcer received eradication therapy: lansoprazole (60 mg/day), clarithromycin (400 mg/day), and amoxicillin (1500 mg/day) for 1 week."3.74Helicobacter pylori eradication reduces platelet count in patients without idiopathic thrombocytopenic purpura. ( Arakawa, Y; Hatta, Y; Hayashi, I; Iwamoto, M; Kato, K; Kurihara, R; Kurosaka, H; Matsukawa, Y; Mizuno, S; Sawada, S, 2007)
"pylori infection and idiopathic thrombocytopenic purpura (ITP)."2.42[Evaluation of the efficacy of an Helicobacter pylori eradication treatment for idiopathic thrombocytopenic purpura patients]. ( Hirashima, N; Ito, K; Kato, A; Kato, H; Kondo, H; Matsunaga, S; Nukaya, H; Sakakibara, K; Sakamoto, T; Tanaka, Y, 2004)
"A 53-year-old woman had demonstrated idiopathic thrombocytopenic purpura (ITP) and iron deficiency anemia (IDA) since 1978."1.35Iron deficiency anemia successfully treated by Helicobacter pylori eradication in a patient with idiopathic thrombocytopenic purpura. ( ASAKA, M; HASHINO, S; IMAMURA, M; KAHATA, K; KONDO, T; MORITA, R; OKADA, K; ONOZAWA, M; TAKAHATA, M, 2009)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's14 (82.35)29.6817
2010's3 (17.65)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kim, H1
Lee, WS1
Lee, KH1
Bae, SH1
Kim, MK1
Joo, YD1
Zang, DY1
Jo, JC1
Lee, SM1
Lee, JH2
Kim, DY1
Ryoo, HM1
Hyun, MS1
Kim, HJ1
Tsumoto, C1
Tominaga, K1
Okazaki, H1
Tanigawa, T1
Yamagami, H1
Watanabe, K3
Nakao, T1
Koh, K1
Watanabe, T1
Fujiwara, Y1
Yamane, T1
Oshitani, N1
Hino, M1
Higuchi, K1
Arakawa, T1
MORITA, R1
HASHINO, S1
OKADA, K1
TAKAHATA, M1
ONOZAWA, M1
KAHATA, K1
KONDO, T1
IMAMURA, M3
ASAKA, M3
Matsukawa, Y2
Iwamoto, M2
Kato, K2
Mizuno, S2
Gon, Y1
Hemmi, A1
Shirinskaya, N1
Takeuchi, J1
Sawada, S2
Sato, R2
Murakami, K2
Okimoto, T2
Kodama, M2
Fujioka, T2
Kohda, K1
Kuga, T1
Kogawa, K1
Kanisawa, Y1
Koike, K1
Kuroiwa, G1
Hirayama, Y1
Sato, Y1
Niitsu, Y1
Asaumi, N2
Masuda, K1
Yoshida, C2
Kiguchi, T1
Niiya, M2
Niiya, K2
Tanimoto, M2
Shibakura, M1
Miyajima, H1
Ogata, M1
Ohtsuka, E1
Saburi, Y1
Nasu, M1
Tsutsumi, Y2
Kanamori, H2
Yamato, H2
Ehira, N2
Miura, T1
Kawamura, T2
Obara, S2
Tanaka, J2
Masauzi, N2
Kato, A1
Kato, H1
Hirashima, N1
Sakamoto, T1
Nukaya, H1
Ito, K1
Matsunaga, S1
Kondo, H1
Tanaka, Y1
Sakakibara, K1
Umehara, S1
Mori, A1
Ogura, N1
Konno, M1
Sayan, O1
Akyol Erikci, A1
Ozturk, A1
Hatta, Y1
Kurihara, R1
Arakawa, Y1
Kurosaka, H1
Hayashi, I1
Litton, G1
Goto, H1
Kikuta, T1
Ota, A1
Tsuji, H1
Hino, R1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy of Helicobacter Pylori Eradication for the 1st Line Treatment of Immune Thrombocytopenic Purpura (ITP) Patients With Moderate Thrombocytopenia[NCT01255332]26 participants (Anticipated)Observational2010-09-30Recruiting
Helicobacter Pylori and it's Hematological Impact[NCT03629587]100 participants (Actual)Observational2016-09-27Completed
Efficacy of Helicobacter Pylori Eradication for the Treatment of Chronic or Persistent Immune Thrombocytopenic Purpura Patients With Moderate Thrombocytopenia: Multicenter Prospective Randomized Phase 3 Study[NCT03177629]Phase 354 participants (Anticipated)Interventional2017-05-23Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for lansoprazole and Autoimmune Thrombocytopenia

ArticleYear
[Evaluation of the efficacy of an Helicobacter pylori eradication treatment for idiopathic thrombocytopenic purpura patients].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2004, Volume: 101, Issue:11

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Amoxicillin; Anti-Infective Agents; Clarithromycin; D

2004
[Helicobacter pylori eradication therapy for children].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 11

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anemia, Iron-Deficiency; Anti-Bacterial Agents

2005

Trials

4 trials available for lansoprazole and Autoimmune Thrombocytopenia

ArticleYear
Efficacy of Helicobacter pylori eradication for the 1st line treatment of immune thrombocytopenia patients with moderate thrombocytopenia.
    Annals of hematology, 2015, Volume: 94, Issue:5

    Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Clarithromycin; Female; Helicobacter Infections; Helicoba

2015
Efficacy of Helicobacter pylori eradication for the 1st line treatment of immune thrombocytopenia patients with moderate thrombocytopenia.
    Annals of hematology, 2015, Volume: 94, Issue:5

    Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Clarithromycin; Female; Helicobacter Infections; Helicoba

2015
Efficacy of Helicobacter pylori eradication for the 1st line treatment of immune thrombocytopenia patients with moderate thrombocytopenia.
    Annals of hematology, 2015, Volume: 94, Issue:5

    Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Clarithromycin; Female; Helicobacter Infections; Helicoba

2015
Efficacy of Helicobacter pylori eradication for the 1st line treatment of immune thrombocytopenia patients with moderate thrombocytopenia.
    Annals of hematology, 2015, Volume: 94, Issue:5

    Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Clarithromycin; Female; Helicobacter Infections; Helicoba

2015
Efficacy of Helicobacter pylori eradication for the 1st line treatment of immune thrombocytopenia patients with moderate thrombocytopenia.
    Annals of hematology, 2015, Volume: 94, Issue:5

    Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Clarithromycin; Female; Helicobacter Infections; Helicoba

2015
Efficacy of Helicobacter pylori eradication for the 1st line treatment of immune thrombocytopenia patients with moderate thrombocytopenia.
    Annals of hematology, 2015, Volume: 94, Issue:5

    Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Clarithromycin; Female; Helicobacter Infections; Helicoba

2015
Efficacy of Helicobacter pylori eradication for the 1st line treatment of immune thrombocytopenia patients with moderate thrombocytopenia.
    Annals of hematology, 2015, Volume: 94, Issue:5

    Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Clarithromycin; Female; Helicobacter Infections; Helicoba

2015
Efficacy of Helicobacter pylori eradication for the 1st line treatment of immune thrombocytopenia patients with moderate thrombocytopenia.
    Annals of hematology, 2015, Volume: 94, Issue:5

    Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Clarithromycin; Female; Helicobacter Infections; Helicoba

2015
Efficacy of Helicobacter pylori eradication for the 1st line treatment of immune thrombocytopenia patients with moderate thrombocytopenia.
    Annals of hematology, 2015, Volume: 94, Issue:5

    Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Clarithromycin; Female; Helicobacter Infections; Helicoba

2015
Long-term efficacy of Helicobacter pylori eradication in patients with idiopathic thrombocytopenic purpura: 7-year follow-up prospective study.
    Annals of hematology, 2009, Volume: 88, Issue:8

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adrenal Cortex Hormones; Adult; Aged; Amoxicillin; Clarithr

2009
Effect of Helicobacter pylori eradication on platelet recovery in patients with chronic idiopathic thrombocytopenic purpura.
    Archives of internal medicine, 2004, Sep-27, Volume: 164, Issue:17

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Anti-Infective Agents; Chronic Disease;

2004
Randomized study of Helicobacter pylori eradication therapy and proton pump inhibitor monotherapy for idiopathic thrombocytopenic purpura.
    Annals of hematology, 2005, Volume: 84, Issue:12

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents

2005

Other Studies

11 other studies available for lansoprazole and Autoimmune Thrombocytopenia

ArticleYear
Iron deficiency anemia successfully treated by Helicobacter pylori eradication in a patient with idiopathic thrombocytopenic purpura.
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2009, Volume: 50, Issue:11

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anemia, Iron-Deficiency; Clarithromycin; Drug

2009
Long term changes in platelet counts after H. pylori eradication in non-ITP patients.
    Platelets, 2010, Volume: 21, Issue:8

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer

2010
Development of corpus atrophic gastritis may be associated with Helicobacter pylori-related idiopathic thrombocytopenic purpura.
    Journal of gastroenterology, 2011, Volume: 46, Issue:8

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Clarithrom

2011
Effect of Helicobacter pylori eradication on platelet recovery in Japanese patients with chronic idiopathic thrombocytopenic purpura and secondary autoimmune thrombocytopenic purpura.
    British journal of haematology, 2002, Volume: 118, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Amoxicillin; Anti-Bacterial

2002
[Helicobacter pylori eradication based upon a drug sensitivity test effectively increased platelet count in a patient with refractory idiopathic thrombocytopenic purpura].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2003, Volume: 44, Issue:7

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Bacterial Agents; Helicobacter Infections; Helicobacte

2003
Secondary eradication of Helicobacter pylori was effective against refractory idiopathic thrombocytopenic purpura.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2003, Volume: 14, Issue:8

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Bacterial Agents; Blood Platelets; Drug Therapy, Combi

2003
Effect of lansoprazole for an idiopathic thrombocytopenic purpura patient with Helicobacter pylori infection who did not respond to prednisolone treatment.
    Clinical and laboratory haematology, 2004, Volume: 26, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Anti-Infective Agents; Helicobacter Infections; Helic

2004
The Efficacy of Helicobacter pylori eradication in the treatment of idiopathic thrombocytopenic purpura--the first study in Turkey.
    Acta haematologica, 2006, Volume: 116, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Amoxicillin; Clarithromycin

2006
Helicobacter pylori eradication reduces platelet count in patients without idiopathic thrombocytopenic purpura.
    Platelets, 2007, Volume: 18, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clar

2007
Refractory idiopathic thrombocytopenic purpura treated with the soluble tumor necrosis factor receptor etanercept.
    American journal of hematology, 2008, Volume: 83, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Bacterial Agents; Colchicine; Combined Modality

2008
[Successful treatment of refractory idiopathic thrombocytopenic purpura by eradication of Helicobacter pylori].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2001, Volume: 42, Issue:12

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Bacterial Agents; Clarithromycin; Drug Th

2001