lansoprazole has been researched along with Anesthesia in 3 studies
Lansoprazole: A 2,2,2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS. Lansoprazole is a racemic mixture of (R)- and (S)-isomers.
Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Cmax (maximum serum concentration) and AUC (area under the serum concentration-time curve) for (+)-lansoprazole were 5-6 times greater than those for (-)-lansoprazole, whereas for (+)-5-hydroxylansoprazole both values were significantly smaller than those for the (-) enantiomer." | 1.30 | Pharmacokinetic differences between lansoprazole enantiomers in rats. ( Arimori, K; Katsuki, H; Nakano, M; Yasuda, K, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yenişehirli, A | 1 |
| Naseri, E | 1 |
| Coruzzi, G | 1 |
| Adami, M | 1 |
| Bertaccini, G | 1 |
| Arimori, K | 1 |
| Yasuda, K | 1 |
| Katsuki, H | 1 |
| Nakano, M | 1 |
3 other studies available for lansoprazole and Anesthesia
| Article | Year |
|---|---|
Omeprazole, lansoprazole and pantoprazole had no effect on blood pressure and electrocardiogram of anesthetized rat.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anesthesia; Animals; Blood Pressure; Dose-Response Relation | 2008 |
Gastric antisecretory activity of lansoprazole in different experimental models: comparison with omeprazole.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anesthesia; Animals; Anti-Ulcer Agents; Cats; Female; Gastr | 1995 |
Pharmacokinetic differences between lansoprazole enantiomers in rats.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anesthesia; Animals; Anti-Ulcer Agents; Area Under Curve; C | 1998 |