lanatosides and Tachycardia--Paroxysmal

The treatment of paroxysmal supraventricular tachycardia (PSVT) in infancy with digitalis, adenosine triphosphate (ATP) and verapamil is reported. Treatment was successful in about 90% of the patients treated with ATP and verapamil and in 61--71% of the patients treated with digitalis (Lanatoside C). Verapamil terminated the tachycardia within 2 minutes of administration in most instances and ATP in less than 1 minute. Digitalis, however, took as long as 2 hours; it was therefore excluded as the drug of first choice in emergencies, and is better suited for treating patients with poor hemodynamics. Side effects with ATP are common but short-lived. With verapamil, side effects are rare, but may be serious if certain contraindications are not taken into account. Digitalis in the dose used in this trial rarely produced side effects. We conclude that ATP or verapamil is the drug of first choice for quick termination of PSVT in infancy.

Topics: Adenosine Triphosphate; Child; Child, Preschool; Digitalis; Female; Heart Rate; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Lanatosides; Male; Plants, Medicinal; Plants, Toxic; Tachycardia, Paroxysmal; Verapamil

Topics: Aged; Alprenolol; Anti-Arrhythmia Agents; Drug Therapy, Combination; Humans; Lanatosides; Male; Middle Aged; Procainamide; Recurrence; Spironolactone; Strophanthins; Tachycardia, Paroxysmal

Topics: Adrenergic beta-Antagonists; Adult; Aged; Electric Countershock; Female; Heart Block; Humans; Lanatosides; Male; Middle Aged; Tachycardia, Paroxysmal

Topics: Ajmaline; Apgar Score; Arrhythmias, Cardiac; Cesarean Section; Digoxin; Electrocardiography; Extraction, Obstetrical; Female; Fetus; Heart Block; Humans; Infant; Infant, Newborn; Lanatosides; Pregnancy; Prenatal Diagnosis; Tachycardia; Tachycardia, Paroxysmal; Ventricular Fibrillation; Verapamil; Wolff-Parkinson-White Syndrome

Topics: Anti-Bacterial Agents; Anticoagulants; Aortic Coarctation; Bradycardia; Chlorothiazide; Diet, Sodium-Restricted; Digitalis Glycosides; Digitoxin; Digoxin; Drug Tolerance; Electrocardiography; Endocardial Fibroelastosis; Furosemide; Heart Block; Heart Defects, Congenital; Heart Failure; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Lanatosides; Myocarditis; Organomercury Compounds; Oxygen Inhalation Therapy; Potassium Chloride; Pulmonary Edema; Tachycardia; Tachycardia, Paroxysmal; Transposition of Great Vessels

Topics: Digitalis Glycosides; Electrocardiography; Humans; Infant, Newborn; Infant, Newborn, Diseases; Lanatosides; Male; Promazine; Quinidine; Tachycardia, Paroxysmal

Topics: Atrial Flutter; Biomedical Research; Cardiac Glycosides; Drug Therapy; Drug Tolerance; Electrocardiography; Guinea Pigs; Heart Block; Heart Diseases; Humans; Lanatosides; Plants, Medicinal; Proscillaridin; Tachycardia; Tachycardia, Paroxysmal

Topics: Cardiac Glycosides; Humans; Lanatosides; Myocardial Infarction; Tachycardia; Tachycardia, Paroxysmal; Tachycardia, Ventricular

Topics: Humans; Lanatosides; Tachycardia; Tachycardia, Paroxysmal