lanatosides and Atrial-Fibrillation

Topics: Atrial Fibrillation; Atrial Flutter; Cardiac Surgical Procedures; Digitalis; Digitalis Glycosides; Digoxin; Electrocardiography; Heart Block; Heart Failure; Humans; Isoproterenol; Lanatosides; Mitral Valve Stenosis; Pacemaker, Artificial; Tachycardia; Thoracic Surgery; Toxicology; Ventricular Fibrillation

Clinical open trials of beta-methyldigoxin were carried out in 15 institutions in order to examine the effect, usefulness and ease of its oral administration. In the case of oral digitalization with 0.2 mg, 3 times daily, an effect was obtained in all of 13 cases of congestive heart failure accompanied by atrial fibrillation or flutter. The average time and dose required for digitalization were about 50 hours and 1.27 mg respectively. In 9 of the 13 cases, the effect was achieved within 48 hours. The average maintenance does of beta-methyldigoxin in 102 cases of congestive heart failure with atrial fibrillation was 0.177 mg per day. About 75% of the cases were maintained with 0.15 to 0.2 mg. This range of dose of beta-methyldigoxin was much smaller than that of digoxin in our series. This can be ascribed to a higher absorption rate of beta-methyldigoxin from the digestive tract. Studies on the cases in which patients previously treated with other glycosides were switched over to beta-methyldigoxin revealed that 1 mg of beta-methyldigoxin is equivalent to 1.8 mg of digoxin or to 0.59 mg of digitoxin. The usefulness and ease of beta-methyldigoxin in maintenance was evaluated as being somewhat superior to other cardiac glycosides, according to the global judgement of the physicians. The observed side effects were similar to those of other glycosides in frequency and character.

Topics: Administration, Oral; Adult; Aged; Atrial Fibrillation; Clinical Trials as Topic; Digitoxin; Digoxin; Dose-Response Relationship, Drug; Female; Heart Failure; Humans; Lanatosides; Male; Middle Aged; Proscillaridin

To investigate the effectiveness and safety of various agents on paroxysmal atrial fibrillation in the elderly over 75 years old.. Totally 264 in-patients (75-91 years old, 185 males and 79 females) with atrial fibrillation history of less than 7 days were enrolled in this study. A total of 611 atrial fibrillation episodes were recorded, but 130 episodes (22.3%) of atrial fibrillation were auto-converted to sinus rhythm. The rest 481 episodes of atrial fibrillation were divided into six groups based on the drug used.. The cardioversion ratio of atrial fibrillation were 9.5%, 46.9%, 71.7%, 55.9%, 32.7%, and 73.6% in control, cedilanid, amiodarone, propafenone, verapamil, and quinidine groups, respectively. Ventricular rate control were 5.4%, 83.6%, 84.9%, 77.9%, 78.8%, and 11.3% in those groups, respectively. The total effective rates of amiodarone and cedilanid groups were the highest. When the ventricular rate was controlled to below 90 bpm, the patients would almost complain of no discomfort. No severe side-effect was observed in each group.. Amiodarone and cedilanid may be the proper drugs for the treatment of paroxysmal atrial fibrillation in the elderly. The above antiarrhythmics in each therapeutic group were relatively safe and effective.

Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Bradycardia; Cardiac Glycosides; Female; Heart Rate; Humans; Lanatosides; Male; Nausea; Propafenone

Topics: Aged; Atrial Fibrillation; Cardiac Catheterization; Electrocardiography; Female; Heart Conduction System; Heart Rate; Heart Ventricles; Humans; Lanatosides; Tachycardia

Topics: Adult; Arrhythmias, Cardiac; Atrial Fibrillation; Electrocardiography; Heart Conduction System; Humans; Lanatosides; Male

Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Digitalis Glycosides; Digoxin; Drug Synergism; Drug Therapy, Combination; Electrocardiography; Heart Conduction System; Heart Rate; Humans; Lanatosides; Propranolol; Quinidine; Refractory Period, Electrophysiological; Tachycardia

Topics: Atrial Fibrillation; Cochlea; Ear, Middle; Female; Hearing Disorders; Humans; Lanatosides; Middle Aged; Nausea; Vestibule, Labyrinth; Vomiting

Topics: Aged; Atrial Fibrillation; Electrocardiography; Heart Conduction System; Heart Rate; Humans; Lanatosides; Male; Tachycardia; Wolff-Parkinson-White Syndrome

Topics: Adult; Aged; Arrhythmias, Cardiac; Atrial Fibrillation; Digitalis Glycosides; Female; Heart Diseases; Humans; Lanatosides; Male; Middle Aged

Topics: Aged; Atrial Fibrillation; Humans; Injections, Intravenous; Lanatosides; Tachycardia

Topics: Adult; Aged; Arrhythmias, Cardiac; Atrial Fibrillation; Female; Heart Diseases; Humans; Lanatosides; Male; Middle Aged

Topics: Aged; Atrial Fibrillation; Blood Flow Velocity; Body Weight; Coronary Disease; Electrocardiography; Female; Heart Diseases; Heart Failure; Humans; Hypertension; Hyperthyroidism; Intestinal Absorption; Lanatosides; Male; Middle Aged; Pulmonary Heart Disease; Pulse

Topics: Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Atrial Fibrillation; Biomedical Research; Coronary Disease; Drug Therapy; Exercise Test; Goiter; Graves Disease; Hemodynamics; Humans; Hypertension; Lanatosides; Sympatholytics; Toxicology

Topics: Aminophylline; Angiotensins; Atrial Fibrillation; Autopsy; Blood Flow Velocity; Blood Pressure; Blood Pressure Determination; Blood Volume; Blood Volume Determination; Cardiac Catheterization; Coronary Disease; Drug Therapy; Endocarditis; Endocarditis, Subacute Bacterial; Heart Defects, Congenital; Heart Failure; Heart Function Tests; Humans; Hypertension; Lanatosides; Mitral Valve Stenosis; Norepinephrine; Pathology; Radioisotopes; Rheumatic Heart Disease; Syphilis; Syphilis, Cardiovascular

Topics: Atrial Fibrillation; Cardiac Glycosides; Geriatrics; Heart Failure; Humans; Lanatosides; Tachycardia

Topics: Atrial Fibrillation; Atrial Flutter; Cardiac Surgical Procedures; Coronary Disease; Electric Countershock; Heart Block; Hypertension; Hyperthyroidism; Lanatosides; Quinidine; Rheumatic Heart Disease; Tachycardia; Thoracic Surgery; Toxicology

Topics: Atrial Fibrillation; Blood Pressure; Cats; Electrocardiography; Heart; Hypothermia; Hypothermia, Induced; Lanatosides; Pharmacology; Research

Topics: Arrhythmia, Sinus; Arrhythmias, Cardiac; Atrial Fibrillation; Coronary Disease; Deslanoside; Heart Defects, Congenital; Heart Failure; Humans; Lanatosides; Myocarditis; Pulmonary Heart Disease; Tachycardia

Topics: Aortic Valve Stenosis; Atrial Fibrillation; Bronchitis; Capillaries; Heart Failure; Humans; Lanatosides; Mitral Valve Stenosis; Pharmacology; Respiratory Insufficiency; Rheumatic Heart Disease; Strophanthins

Topics: Adolescent; Angina Pectoris; Arrhythmias, Cardiac; Atrial Fibrillation; Child; Coronary Disease; Deslanoside; Geriatrics; Heart Block; Heart Failure; Humans; Hypertension; Lanatosides; Myocardial Infarction; Pharmacology; Pulmonary Edema; Pulmonary Fibrosis; Pulmonary Heart Disease; Tachycardia; Thrombophlebitis; Toxicology; Water-Electrolyte Balance

Topics: Atrial Fibrillation; Digitalis; Digitalis Glycosides; Lanatosides; Plant Extracts; Tachycardia

Topics: Atrial Fibrillation; Digitalis; Digitalis Glycosides; Digitoxin; Humans; Lanatosides; Plant Extracts

Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Brugada Syndrome; Cardiac Conduction System Disease; Digitalis; Digitalis Glycosides; Heart Conduction System; Humans; Lanatosides