Page last updated: 2024-10-30

lamotrigine and Vomiting

lamotrigine has been researched along with Vomiting in 5 studies

Vomiting: The forcible expulsion of the contents of the STOMACH through the MOUTH.

Research Excerpts

ExcerptRelevanceReference
"To evaluate and compare the effects of concomitant lamotrigine (LTG) or carbamazepine (CBZ) on the incidence of treatment-emergent adverse events (TEAEs) in patients taking adjunctive eslicarbazepine acetate (ESL) for focal (partial-onset) seizures (FS)."9.27Tolerability of adjunctive eslicarbazepine acetate according to concomitant lamotrigine or carbamazepine use: A subgroup analysis of three phase III trials in adults with focal (partial-onset) seizures. ( Abou-Khalil, B; Blum, D; Cheng, H; Gama, H; Grinnell, T; Jung, J; Klein, P; Rocha, F; Ryvlin, P; Shah, A; Specchio, LM, 2018)
"To compare the pharmacokinetics (PK) of lamotrigine (LTG) when converting from twice-daily immediate-release (LTG-IR) to once-daily extended-release (LTG-XR) in subjects with epilepsy."9.13Steady-state pharmacokinetics of lamotrigine when converting from a twice-daily immediate-release to a once-daily extended-release formulation in subjects with epilepsy (The COMPASS Study). ( Ali, I; Hammer, AE; Job, S; Lemme, F; Messenheimer, JA; Oliver-Willwong, R; Tompson, DJ; Vuong, A; Zhu, L, 2008)
"The purpose of this case series is to characterize a recently identified association of the antiepileptic drug (AED) lamotrigine with aseptic meningitis based on cases reported to the Food and Drug Administration (FDA)'s Adverse Event Reporting System (AERS) database."7.78Lamotrigine and aseptic meningitis. ( Avigan, M; Kortepeter, C; Simms, KM, 2012)
"To evaluate and compare the effects of concomitant lamotrigine (LTG) or carbamazepine (CBZ) on the incidence of treatment-emergent adverse events (TEAEs) in patients taking adjunctive eslicarbazepine acetate (ESL) for focal (partial-onset) seizures (FS)."5.27Tolerability of adjunctive eslicarbazepine acetate according to concomitant lamotrigine or carbamazepine use: A subgroup analysis of three phase III trials in adults with focal (partial-onset) seizures. ( Abou-Khalil, B; Blum, D; Cheng, H; Gama, H; Grinnell, T; Jung, J; Klein, P; Rocha, F; Ryvlin, P; Shah, A; Specchio, LM, 2018)
"To compare the pharmacokinetics (PK) of lamotrigine (LTG) when converting from twice-daily immediate-release (LTG-IR) to once-daily extended-release (LTG-XR) in subjects with epilepsy."5.13Steady-state pharmacokinetics of lamotrigine when converting from a twice-daily immediate-release to a once-daily extended-release formulation in subjects with epilepsy (The COMPASS Study). ( Ali, I; Hammer, AE; Job, S; Lemme, F; Messenheimer, JA; Oliver-Willwong, R; Tompson, DJ; Vuong, A; Zhu, L, 2008)
"The purpose of this case series is to characterize a recently identified association of the antiepileptic drug (AED) lamotrigine with aseptic meningitis based on cases reported to the Food and Drug Administration (FDA)'s Adverse Event Reporting System (AERS) database."3.78Lamotrigine and aseptic meningitis. ( Avigan, M; Kortepeter, C; Simms, KM, 2012)
"Lamotrigine was effective for the adjunctive treatment of partial seizures in children and demonstrated an acceptable safety profile."2.69A placebo-controlled trial of lamotrigine add-on therapy for partial seizures in children. Lamictal Pediatric Partial Seizure Study Group. ( Billard, C; Casale, E; Duchowny, M; Gilman, J; Graf, WD; Manasco, P; Pellock, JM; Risner, M; Womble, G, 1999)
"To identify adverse drug reactions associated with lamotrigine in children and compare the safety profile with other antiepileptic drugs."2.52Safety of lamotrigine in paediatrics: a systematic review. ( Choonara, I; Egunsola, O; Sammons, HM, 2015)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's1 (20.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abou-Khalil, B1
Klein, P1
Shah, A1
Ryvlin, P1
Specchio, LM1
Gama, H1
Rocha, F1
Blum, D1
Grinnell, T1
Cheng, H1
Jung, J1
Egunsola, O1
Choonara, I1
Sammons, HM1
Simms, KM1
Kortepeter, C1
Avigan, M1
Tompson, DJ1
Ali, I1
Oliver-Willwong, R1
Job, S1
Zhu, L1
Lemme, F1
Hammer, AE1
Vuong, A1
Messenheimer, JA1
Duchowny, M1
Pellock, JM1
Graf, WD1
Billard, C1
Gilman, J1
Casale, E1
Womble, G1
Risner, M1
Manasco, P1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
An Open-label, Double Conversion Study to Characterize the Pharmacokinetics of Lamotrigine When Switching Patients With Epilepsy on LAMICTAL Immediate-release to Extended-release Formulation and Vice Versa[NCT00264615]Phase 345 participants Interventional2005-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for lamotrigine and Vomiting

ArticleYear
Safety of lamotrigine in paediatrics: a systematic review.
    BMJ open, 2015, Jun-12, Volume: 5, Issue:6

    Topics: Abdominal Pain; Anticonvulsants; Child; Dizziness; Drug Therapy, Combination; Exanthema; Headache; H

2015

Trials

3 trials available for lamotrigine and Vomiting

ArticleYear
Tolerability of adjunctive eslicarbazepine acetate according to concomitant lamotrigine or carbamazepine use: A subgroup analysis of three phase III trials in adults with focal (partial-onset) seizures.
    Epilepsy research, 2018, Volume: 147

    Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Dibenzazepines; Diplopia; Dose-Response Re

2018
Steady-state pharmacokinetics of lamotrigine when converting from a twice-daily immediate-release to a once-daily extended-release formulation in subjects with epilepsy (The COMPASS Study).
    Epilepsia, 2008, Volume: 49, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Area Under Curve;

2008
A placebo-controlled trial of lamotrigine add-on therapy for partial seizures in children. Lamictal Pediatric Partial Seizure Study Group.
    Neurology, 1999, Nov-10, Volume: 53, Issue:8

    Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Dose-Response Relationship, Drug; Double-Blind

1999

Other Studies

1 other study available for lamotrigine and Vomiting

ArticleYear
Lamotrigine and aseptic meningitis.
    Neurology, 2012, Mar-20, Volume: 78, Issue:12

    Topics: Adolescent; Adult; Aged; Algorithms; Animals; Anticonvulsants; Antidepressive Agents; Bipolar Disord

2012