lamotrigine has been researched along with Unverricht-Lundborg Syndrome in 1 studies
Unverricht-Lundborg Syndrome: An autosomal recessive condition characterized by recurrent myoclonic and generalized seizures, ATAXIA, slowly progressive intellectual deterioration, DYSARTHRIA, and intention tremor. Myoclonic seizures are severe and continuous, and tend to be triggered by movement, stress, and sensory stimuli. The age of onset is between 8 and 13 years, and the condition is relatively frequent in the Baltic region, especially Finland. (From Menkes, Textbook of Child Neurology, 5th ed, pp109-110)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Persistence of invalidating action myoclonus is a major problem." | 2.72 | Lack of efficacy and potential aggravation of myoclonus with lamotrigine in Unverricht-Lundborg disease. ( Crespel, A; Gelisse, P; Genton, P, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Genton, P | 1 |
| Gelisse, P | 1 |
| Crespel, A | 1 |
1 trial available for lamotrigine and Unverricht-Lundborg Syndrome
| Article | Year |
|---|---|
Lack of efficacy and potential aggravation of myoclonus with lamotrigine in Unverricht-Lundborg disease.
Topics: Acute Disease; Adult; Age of Onset; Anticonvulsants; Dose-Response Relationship, Drug; Drug Therapy, | 2006 |