Page last updated: 2024-10-30

lamotrigine and Syndrome

lamotrigine has been researched along with Syndrome in 41 studies

Syndrome: A characteristic symptom complex.

Research Excerpts

ExcerptRelevanceReference
"We conducted a double-blind, placebo-controlled trial of the antiepileptic drug lamotrigine in patients with the Lennox-Gastaut syndrome."9.08Lamotrigine for generalized seizures associated with the Lennox-Gastaut syndrome. Lamictal Lennox-Gastaut Study Group. ( Arvidsson, JF; Barrera, MN; Manasco, P; Motte, J; Mullens, EL; Trevathan, E, 1997)
" We herein present an unusual case of DRESS syndrome due to lamotrigine with reactivation of Epstein-Barr virus, which developed autoimmune LE and syndrome of inappropriate antidiuretic hormone secretion."7.83Autoimmune Limbic Encephalitis and Syndrome of Inappropriate Antidiuretic Hormone Secretion Associated with Lamotrigine-induced Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) Syndrome. ( Ozisik, L; Saka, E; Tanriover, MD, 2016)
" We report here a case of Drug Reaction with Eosinophilia and Systemic Symptoms apparently precipitated by the associated use of lamotrigine and cyclobenzaprine."7.78Erythema multiforme vs. DRESS syndrome associated with the combined use of lamotrigine and cyclobenzaprine: a case report. ( Bicknell, LT; Sanches, M; Schatte, DJ, 2012)
"To report a case of lamotrigine-induced drug rash with eosinophilia and systemic symptoms (DRESS) syndrome with pancreatitis as the initial visceral involvement."7.76First report of lamotrigine-induced drug rash with eosinophilia and systemic symptoms syndrome with pancreatitis. ( Augusto, JF; Croue, A; Dib, N; Lerolle, N; Mercat, A; Peres, M; Roquin, G, 2010)
"Anticonvulsant hypersensitivity syndrome (AHS) developing to lamotrigine, a non-aromatic anticonvulsant, has rarely been reported."7.73Anticonvulsant hypersensitivity syndrome to lamotrigine confirmed by lymphocyte stimulation in vitro. ( Gogtay, NJ; Kanchan, S; Karande, S; Kshirsagar, NA, 2006)
"If the positive effect of lamotrigine in patients with SUNCT is confirmed in other cases, lamotrigine could become the first specific treatment for SUNCT syndrome."7.71SUNCT syndrome responsive to lamotrigine. ( Gutierrez-Garcia, JM, 2002)
"An 8-year-old girl with Lennox-Gastaut syndrome showed a partial reduction in seizure frequency when lamotrigine (LTG), 15 mg/kg per day, was added to clobazam (CLB) and vigabatrin (VGB)."7.70Myoclonic status epilepticus following high-dosage lamotrigine therapy. ( Belmonte, A; Guerrini, R; Parmeggiani, L; Perucca, E, 1999)
"The SUNCT syndrome is characterized by a short-lasting headache in the first division of the trigeminal nerve, associated with ipsilateral autonomic symptoms."6.42Influence of lamotrigine over the SUNCT syndrome: one patient follow-up for two years. ( Kowacs, PA; Piovesan, EJ; Siow, C; Werneck, LC, 2003)
"The syndrome is characterized by mental impairment, frequent seizures of multiple types that are particularly resistant to treatment, and high rates of seizure-related injury."5.36The cost effectiveness of rufinamide in the treatment of Lennox-Gastaut syndrome in the UK. ( Benedict, A; Maclaine, G; Verdian, L, 2010)
"Lamotrigine was replaced by sodium valproate for one patient."5.33[Drug hypersensitivity syndrome with lamotrigine two cases in elderly]. ( Bourdel-Marchasson, I; Jeandel, PY; Rainfray, M; Traissac, T, 2005)
"We conducted a double-blind, placebo-controlled trial of the antiepileptic drug lamotrigine in patients with the Lennox-Gastaut syndrome."5.08Lamotrigine for generalized seizures associated with the Lennox-Gastaut syndrome. Lamictal Lennox-Gastaut Study Group. ( Arvidsson, JF; Barrera, MN; Manasco, P; Motte, J; Mullens, EL; Trevathan, E, 1997)
"Accumulating data suggest that lamotrigine, which has been available for adult use in epilepsy for more than a decade in clinical practice, also confers effective, well-tolerated control of a range of childhood epilepsies."4.81Efficacy and safety of lamotrigine in pediatric patients. ( Messenheimer, J, 2002)
" We herein present an unusual case of DRESS syndrome due to lamotrigine with reactivation of Epstein-Barr virus, which developed autoimmune LE and syndrome of inappropriate antidiuretic hormone secretion."3.83Autoimmune Limbic Encephalitis and Syndrome of Inappropriate Antidiuretic Hormone Secretion Associated with Lamotrigine-induced Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) Syndrome. ( Ozisik, L; Saka, E; Tanriover, MD, 2016)
" We report here a case of Drug Reaction with Eosinophilia and Systemic Symptoms apparently precipitated by the associated use of lamotrigine and cyclobenzaprine."3.78Erythema multiforme vs. DRESS syndrome associated with the combined use of lamotrigine and cyclobenzaprine: a case report. ( Bicknell, LT; Sanches, M; Schatte, DJ, 2012)
" All had dermatological manifestations, eosinophilia and systemic (haematological and hepatic) manifestations that could be attributed to treatment with aromatic AEDs (carbamazepine, 2 patients; lamotrigine, 3 patients; phenytoin, 3 patients)."3.77Risk factors associated with DRESS syndrome produced by aromatic and non-aromatic antipiletic drugs. ( Kochen, S; Pereira de Silva, N; Piquioni, P; Saidon, P, 2011)
"To report a case of lamotrigine-induced drug rash with eosinophilia and systemic symptoms (DRESS) syndrome with pancreatitis as the initial visceral involvement."3.76First report of lamotrigine-induced drug rash with eosinophilia and systemic symptoms syndrome with pancreatitis. ( Augusto, JF; Croue, A; Dib, N; Lerolle, N; Mercat, A; Peres, M; Roquin, G, 2010)
"This report describes the laboratory and physical manifestations of lamotrigine-like toxicity in a young man with refractory epilepsy receiving lamotrigine presenting as anticonvulsant hypersensitivity syndrome (AHS) associated with an abrupt change of drug product."3.74Progressive anticonvulsant hypersensitivity syndrome associated with change of drug product. ( Sabers, A; Sabroe, TP, 2008)
"Anticonvulsant hypersensitivity syndrome (AHS) developing to lamotrigine, a non-aromatic anticonvulsant, has rarely been reported."3.73Anticonvulsant hypersensitivity syndrome to lamotrigine confirmed by lymphocyte stimulation in vitro. ( Gogtay, NJ; Kanchan, S; Karande, S; Kshirsagar, NA, 2006)
"If the positive effect of lamotrigine in patients with SUNCT is confirmed in other cases, lamotrigine could become the first specific treatment for SUNCT syndrome."3.71SUNCT syndrome responsive to lamotrigine. ( Gutierrez-Garcia, JM, 2002)
"An 8-year-old girl with Lennox-Gastaut syndrome showed a partial reduction in seizure frequency when lamotrigine (LTG), 15 mg/kg per day, was added to clobazam (CLB) and vigabatrin (VGB)."3.70Myoclonic status epilepticus following high-dosage lamotrigine therapy. ( Belmonte, A; Guerrini, R; Parmeggiani, L; Perucca, E, 1999)
" The further addition of lamotrigine stopped the seizures but the patient presented with a new onset of opercular syndrome, manifested by severe oral motor apraxia with difficulties in chewing and swallowing and speech."3.70Transient opercular syndrome: a manifestation of uncontrolled epileptic activity. ( Mimouni, M; Shuper, A; Stahl, B, 2000)
" Future studies of formal pharmacokinetic modeling of AEDs during pregnancy and the postpartum period could provide an important step toward achieving effective drug dosing to maintain therapeutic objectives for the mother but, at the same time, to minimize fetal drug exposure."2.42Antiepileptic drug pharmacokinetics during pregnancy and lactation. ( Pennell, PB, 2003)
"The SUNCT syndrome is characterized by a short-lasting headache in the first division of the trigeminal nerve, associated with ipsilateral autonomic symptoms."2.42Influence of lamotrigine over the SUNCT syndrome: one patient follow-up for two years. ( Kowacs, PA; Piovesan, EJ; Siow, C; Werneck, LC, 2003)
" Dosing in generalized seizures is similar to that for partial seizures."2.40Lamotrigine in absence and primary generalized epilepsies. ( Holmes, GL; Mikati, MA, 1997)
"Lamotrigine was beneficial for her SUNA but not for the RES."1.39SUNA and red ear syndrome: a new association and pathophysiological considerations. ( Bakar, NA; Lambru, G; Matharu, M, 2013)
"The syndrome is characterized by mental impairment, frequent seizures of multiple types that are particularly resistant to treatment, and high rates of seizure-related injury."1.36The cost effectiveness of rufinamide in the treatment of Lennox-Gastaut syndrome in the UK. ( Benedict, A; Maclaine, G; Verdian, L, 2010)
"Although epilepsy in AS is considered a generalized epilepsy, there was a high prevalence of partial seizures."1.35Epilepsy in Angelman syndrome: a questionnaire-based assessment of the natural history and current treatment options. ( Braun, EK; Bruno, P; Conant, KD; Nespeca, MP; Said, RR; Thibert, RL; Thiele, EA, 2009)
"Epilepsy is often the most important clinical manifestation of the syndrome, even if its appearance is not constantly precocious."1.35Ring chromosome 20 syndrome: a link between epilepsy onset and neuropsychological impairment in three children. ( Canevini, MP; Dalla Bernardina, B; Darra, F; Fiorini, E; La Selva, L; Lazzarotto, F; Piazzini, A; Vignoli, A; Zucca, C, 2009)
"Lamotrigine was replaced by sodium valproate for one patient."1.33[Drug hypersensitivity syndrome with lamotrigine two cases in elderly]. ( Bourdel-Marchasson, I; Jeandel, PY; Rainfray, M; Traissac, T, 2005)
"This syndrome is accompanied by fever, rash, lymphadenopathy, eosinophilia and affects parenchymal organs."1.32[Anticonvulsant hypersensitivity syndrome]. ( Papp, Z; Török, L, 2004)
"Chorea is a rare side effect of anticonvulsants."1.31Anticonvulsants-induced chorea: a role for pharmacodynamic drug interaction? ( Beach, RL; D'Cruz, O; Tennison, M; Zaatreh, M, 2001)

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (19.51)18.2507
2000's19 (46.34)29.6817
2010's12 (29.27)24.3611
2020's2 (4.88)2.80

Authors

AuthorsStudies
Watkins, LV1
O'Dwyer, M1
Shankar, R1
Packard, E1
Kalayanamitra, R1
Shahid, Z1
Patel, R1
Roy, J1
Maddukari, A1
Groff, A1
Polimera, H1
Golamari, R1
Sahu, N1
Vunnam, R1
Bhatt, D1
Jain, R1
Wiedemann, K1
Stüber, T1
Rehn, M1
Frieauff, E1
Salgado, A1
Oliveira, L1
Sierra-Siegert, M1
Salgado, JV1
Lambru, G1
Bakar, NA1
Matharu, M1
Bicknell, LT1
Sanches, M1
Schatte, DJ1
Pulido Fontes, L1
Mayor Gómez, S1
Ozisik, L1
Tanriover, MD1
Saka, E1
Taillia, H1
Alla, P1
Fournier, B1
Bounolleau, P1
Ouologem, M1
Ricard, D1
Sallansonnet-Froment, M1
de Greslan, T1
Renard, JL1
Thibert, RL1
Conant, KD1
Braun, EK1
Bruno, P1
Said, RR1
Nespeca, MP1
Thiele, EA1
Vignoli, A1
Canevini, MP1
Darra, F1
La Selva, L1
Fiorini, E1
Piazzini, A1
Lazzarotto, F1
Zucca, C1
Dalla Bernardina, B1
Aouam, K1
Ben Romdhane, F1
Loussaief, C1
Salem, R1
Toumi, A1
Belhadjali, H1
Chaabane, A1
Boughattas, NA1
Chakroun, M1
Benedict, A1
Verdian, L1
Maclaine, G1
Sepić-Grahovac, D1
Ruzić Barsić, A1
Ruzić, K1
Grahovac, T1
Dadić-Hero, E1
Roquin, G1
Peres, M1
Lerolle, N1
Dib, N1
Mercat, A1
Croue, A1
Augusto, JF1
Pereira de Silva, N1
Piquioni, P1
Kochen, S1
Saidon, P1
Marriott, DJ1
Periyasamy, P1
Sato, T1
Kuniba, H1
Matsuo, M1
Matsuzaka, T1
Moriuchi, H1
Gutierrez-Garcia, JM1
Bourgeois, BF1
Pennell, PB1
Piovesan, EJ1
Siow, C1
Kowacs, PA1
Werneck, LC1
Papp, Z1
Török, L1
Jeandel, PY1
Traissac, T1
Rainfray, M1
Bourdel-Marchasson, I1
Benbadis, SR1
Karande, S1
Gogtay, NJ1
Kanchan, S1
Kshirsagar, NA1
Kilaru, S1
Bergqvist, AGC1
Sabroe, TP1
Sabers, A1
Motte, J1
Trevathan, E1
Arvidsson, JF1
Barrera, MN1
Mullens, EL1
Manasco, P1
Dulac, O1
Kaminska, A1
Mikati, MA1
Holmes, GL1
Tugendhaft, P1
Simonart, T1
Kukushkin, ML1
Danilova, EI1
Grafova, VN1
Smirnova, VS1
Reshetniak, VK1
Bélanger, S1
Coulombe, G1
Carmant, L1
Guerrini, R1
Belmonte, A1
Parmeggiani, L1
Perucca, E1
D'Andrea, G1
Granella, F1
Cadaldini, M1
Shuper, A1
Stahl, B1
Mimouni, M1
Leone, M1
Rigamonti, A1
Usai, S1
Damico, D1
Grazzi, L1
Bussone, G1
Tilignac, C1
Dordain, G1
Zaatreh, M1
Tennison, M1
D'Cruz, O1
Beach, RL1
Messenheimer, J1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Study of Maternal Pharmacokinetic and Placental Transfer of Levetiracetam[NCT04117425]50 participants (Anticipated)Interventional2022-04-20Recruiting
Verapamil as Adjunctive Seizure Therapy for Children and Young Adults With Dravet Syndrome[NCT01607073]Phase 22 participants (Actual)Interventional2012-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change in Number of Absence Seizures From Week 8 (Baseline) to Week 12

The secondary outcome measure is the change in number of absence seizures from Week 8 (Baseline) to Week 12 (NCT01607073)
Timeframe: Week 8 to Week 12

InterventionAbscence seizures (Number)
Week 8 Baseline165
Week 12 Verapamil 4mg/kg/Day101

Change in Number of General Tonic-clonic Seizures From Week 8 (Baseline) Visit to Week 12 Visit

The primary study endpoint is the change in number of seizures from baseline. Since we only had one participant finish the study, the endpoint was changed to Week 12 visit. Participants were on verapamil for 4 weeks at Week 12. (NCT01607073)
Timeframe: Week 8 (baseline) to Week 12

InterventionGeneral tonic-clonic seizures (Number)
Week 8 Baseline39
Week 12 Verapamil 4mg/kg/Day14

Change in Number of Myoclonic Seizures From Week 8 (Baseline) to Week 12

The secondary outcome is the change in number of myoclonic seizures between baseline Week 8 visit and Week 12 visit. (NCT01607073)
Timeframe: Week 8 (baseline) to Week 12

InterventionMyoclonic seizures (Number)
Week 8 Baseline116
Week 12 Verapamil 4mg/kg/Day175

Reviews

8 reviews available for lamotrigine and Syndrome

ArticleYear
A review of the pharmacotherapeutic considerations for managing epilepsy in people with autism.
    Expert opinion on pharmacotherapy, 2022, Volume: 23, Issue:7

    Topics: Anticonvulsants; Autistic Disorder; Epilepsy; Humans; Lamotrigine; Syndrome

2022
Chronic management of seizures in the syndromes of idiopathic generalized epilepsy.
    Epilepsia, 2003, Volume: 44 Suppl 2

    Topics: Adult; Anticonvulsants; Child; Clinical Trials as Topic; Epilepsy, Generalized; Fructose; Humans; La

2003
Antiepileptic drug pharmacokinetics during pregnancy and lactation.
    Neurology, 2003, Sep-01, Volume: 61, Issue:6 Suppl 2

    Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Epilepsy; Female; Fetal Diseases; Fetal Hypoxia

2003
Influence of lamotrigine over the SUNCT syndrome: one patient follow-up for two years.
    Arquivos de neuro-psiquiatria, 2003, Volume: 61, Issue:3A

    Topics: Analgesics; Headache; Humans; Lamotrigine; Male; Middle Aged; Syndrome; Triazines

2003
Practical management issues for idiopathic generalized epilepsies.
    Epilepsia, 2005, Volume: 46 Suppl 9

    Topics: Age Factors; Age of Onset; Anticonvulsants; Electric Stimulation Therapy; Epilepsy, Generalized; Hum

2005
Use of lamotrigine in Lennox-Gastaut and related epilepsy syndromes.
    Journal of child neurology, 1997, Volume: 12 Suppl 1

    Topics: Anticonvulsants; Child; Diagnosis, Differential; Epilepsy; Epilepsy, Generalized; Humans; Lamotrigin

1997
Lamotrigine in absence and primary generalized epilepsies.
    Journal of child neurology, 1997, Volume: 12 Suppl 1

    Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Epilepsy, Absence; Epilepsy, Generalize

1997
Efficacy and safety of lamotrigine in pediatric patients.
    Journal of child neurology, 2002, Volume: 17 Suppl 2

    Topics: Anticonvulsants; Child; Clinical Trials as Topic; Epilepsy; Humans; Lamotrigine; Syndrome; Treatment

2002

Trials

1 trial available for lamotrigine and Syndrome

ArticleYear
Lamotrigine for generalized seizures associated with the Lennox-Gastaut syndrome. Lamictal Lennox-Gastaut Study Group.
    The New England journal of medicine, 1997, Dec-18, Volume: 337, Issue:25

    Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Double-Blind Method; Epilepsy; Female;

1997

Other Studies

32 other studies available for lamotrigine and Syndrome

ArticleYear
DRESS is a Mess: A Case of Cross Reactivity Between Lacosamide and Lamotrigine.
    South Dakota medicine : the journal of the South Dakota State Medical Association, 2021, Volume: 74, Issue:7

    Topics: Anticonvulsants; Eosinophilia; Humans; Lacosamide; Lamotrigine; Syndrome

2021
Fetal Valproate Syndrome - Still a Problem Today!
    Zeitschrift fur Geburtshilfe und Neonatologie, 2017, Volume: 221, Issue:5

    Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Cesarean Section; Drug Therapy, Combination; Ep

2017
Depersonalization and derealization syndrome: report on a case study and pharmacological management.
    Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999), 2012, Volume: 34, Issue:4

    Topics: Adult; Cyclohexanols; Depersonalization; Female; Humans; Lamotrigine; Selective Serotonin Reuptake I

2012
SUNA and red ear syndrome: a new association and pathophysiological considerations.
    The journal of headache and pain, 2013, Apr-08, Volume: 14

    Topics: Ear Diseases; Erythema; Excitatory Amino Acid Antagonists; Female; Humans; Lamotrigine; Middle Aged;

2013
Erythema multiforme vs. DRESS syndrome associated with the combined use of lamotrigine and cyclobenzaprine: a case report.
    International journal of psychiatry in medicine, 2012, Volume: 44, Issue:4

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Antimanic Agents; Citalopram; Diagnosis, Differenti

2012
SUNCT (Short-lasting unilateral neuralgiform headache attack with conjunctival injection and tearing) associated with pituitary lesion.
    Neurologia (Barcelona, Spain), 2015, Volume: 30, Issue:7

    Topics: Excitatory Amino Acid Antagonists; Headache; Humans; Lamotrigine; Magnetic Resonance Imaging; Male;

2015
Autoimmune Limbic Encephalitis and Syndrome of Inappropriate Antidiuretic Hormone Secretion Associated with Lamotrigine-induced Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) Syndrome.
    Internal medicine (Tokyo, Japan), 2016, Volume: 55, Issue:10

    Topics: Adult; Anticonvulsants; Autoimmune Diseases; Drug Hypersensitivity; Eosinophilia; Exanthema; Female;

2016
[Anticonvulsant hypersensitivity syndrome and lamotrigine-associated anticonvulsant hypersensitivity syndrome].
    Revue neurologique, 2009, Volume: 165, Issue:10

    Topics: Adult; Aged; Anticonvulsants; Bipolar Disorder; Drug Eruptions; Drug Hypersensitivity; Eosinophilia;

2009
Epilepsy in Angelman syndrome: a questionnaire-based assessment of the natural history and current treatment options.
    Epilepsia, 2009, Volume: 50, Issue:11

    Topics: Adolescent; Adult; Angelman Syndrome; Anticonvulsants; Child; Child, Preschool; Clonazepam; Comorbid

2009
Ring chromosome 20 syndrome: a link between epilepsy onset and neuropsychological impairment in three children.
    Epilepsia, 2009, Volume: 50, Issue:11

    Topics: Adult; Age of Onset; Anticonvulsants; Child; Chromosomes, Human, Pair 20; Cognition Disorders; Comor

2009
Hypersensitivity syndrome induced by anticonvulsants: possible cross-reactivity between carbamazepine and lamotrigine.
    Journal of clinical pharmacology, 2009, Volume: 49, Issue:12

    Topics: Adolescent; Anticonvulsants; Carbamazepine; Cross Reactions; Drug Eruptions; Drug Hypersensitivity;

2009
The cost effectiveness of rufinamide in the treatment of Lennox-Gastaut syndrome in the UK.
    PharmacoEconomics, 2010, Volume: 28, Issue:3

    Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Computer Simulation; Cost-Benefit Analy

2010
Neurological and psychiatric aspects of corpus callosum genesis.
    Psychiatria Danubina, 2010, Volume: 22, Issue:2

    Topics: Acrocallosal Syndrome; Adult; Amnesia; Anticonvulsants; Apraxias; Epilepsy, Generalized; Functional

2010
First report of lamotrigine-induced drug rash with eosinophilia and systemic symptoms syndrome with pancreatitis.
    The Annals of pharmacotherapy, 2010, Volume: 44, Issue:12

    Topics: Aged; Drug Eruptions; Eosinophilia; Exanthema; Humans; Lamotrigine; Male; Pancreatitis; Syndrome; Tr

2010
Risk factors associated with DRESS syndrome produced by aromatic and non-aromatic antipiletic drugs.
    European journal of clinical pharmacology, 2011, Volume: 67, Issue:5

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Anticonvulsants; Carbamazepine; Disease Susceptibility;

2011
Anticonvulsant hypersensitivity syndrome secondary to lamotrigine mimicking a septic episode.
    Annals of the Academy of Medicine, Singapore, 2011, Volume: 40, Issue:9

    Topics: Animals; Anticonvulsants; Cattle; Drug Hypersensitivity; Female; Humans; Lamotrigine; Lupus Erythema

2011
[Case of drug-induced hypersensitivity syndrome due to lamotrigine: demonstration of sequential reactivation of herpesviruses].
    No to hattatsu = Brain and development, 2012, Volume: 44, Issue:1

    Topics: Adolescent; Anticonvulsants; Cytomegalovirus; Drug Hypersensitivity; Female; Herpesvirus 4, Human; H

2012
SUNCT syndrome responsive to lamotrigine.
    Headache, 2002, Volume: 42, Issue:8

    Topics: Adult; Analgesics; Anticonvulsants; Conjunctiva; Female; Headache Disorders; Humans; Lamotrigine; Ma

2002
[Anticonvulsant hypersensitivity syndrome].
    Orvosi hetilap, 2004, Aug-08, Volume: 145, Issue:32

    Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Eruptions; Drug

2004
[Drug hypersensitivity syndrome with lamotrigine two cases in elderly].
    Presse medicale (Paris, France : 1983), 2005, Apr-09, Volume: 34, Issue:7

    Topics: Age Factors; Aged; Aged, 80 and over; Anticonvulsants; Drug Hypersensitivity; Epilepsy; Female; Huma

2005
Anticonvulsant hypersensitivity syndrome to lamotrigine confirmed by lymphocyte stimulation in vitro.
    Indian journal of medical sciences, 2006, Volume: 60, Issue:2

    Topics: Anticonvulsants; Child, Preschool; Drug Hypersensitivity; Epilepsy; Humans; In Vitro Techniques; Lam

2006
Current treatment of myoclonic astatic epilepsy: clinical experience at the Children's Hospital of Philadelphia.
    Epilepsia, 2007, Volume: 48, Issue:9

    Topics: Age of Onset; Anticonvulsants; Child; Cognition Disorders; Dietary Fats; Electroencephalography; Epi

2007
Progressive anticonvulsant hypersensitivity syndrome associated with change of drug product.
    Acta neurologica Scandinavica, 2008, Volume: 117, Issue:6

    Topics: Adult; Anticonvulsants; Arthralgia; Arthritis; Drugs, Generic; Epilepsy; Exanthema; Fever; Humans; L

2008
Phenytoin-like hypersensitivity associated with lamotrigine.
    Journal of the American Academy of Dermatology, 1998, Volume: 38, Issue:5 Pt 1

    Topics: Anticonvulsants; Dose-Response Relationship, Drug; Drug Eruptions; Exanthema; Humans; Lamotrigine; P

1998
[Effect of lamotrigine on development of neurogenic pain syndrome in rats].
    Biulleten' eksperimental'noi biologii i meditsiny, 1998, Volume: 125, Issue:5

    Topics: Analgesics; Animals; Anticonvulsants; Convulsants; Lamotrigine; Neurons; Pain; Pain Measurement; Pen

1998
Role of vigabatrin and lamotrigine in treatment of childhood epileptic syndromes.
    Epilepsia, 1998, Volume: 39, Issue:8

    Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Child; Child, Preschool; Drug Therapy, Combination;

1998
Myoclonic status epilepticus following high-dosage lamotrigine therapy.
    Brain & development, 1999, Volume: 21, Issue:6

    Topics: Anticonvulsants; Child; Electroencephalography; Epilepsies, Myoclonic; Epilepsy, Absence; Female; Hu

1999
Possible usefulness of lamotrigine in the treatment of SUNCT syndrome.
    Neurology, 1999, Oct-22, Volume: 53, Issue:7

    Topics: Aged; Calcium Channel Blockers; Conjunctival Diseases; Dose-Response Relationship, Drug; Female; Hea

1999
Transient opercular syndrome: a manifestation of uncontrolled epileptic activity.
    Acta neurologica Scandinavica, 2000, Volume: 101, Issue:5

    Topics: Anticonvulsants; Child; Diagnosis, Differential; Electroencephalography; Epilepsy, Frontal Lobe; Hum

2000
Two new SUNCT cases responsive to lamotrigine.
    Cephalalgia : an international journal of headache, 2000, Volume: 20, Issue:9

    Topics: Aged; Conjunctival Diseases; Female; Headache; Humans; Lacrimal Apparatus Diseases; Lamotrigine; Mal

2000
[SUNCT syndrome sensitive to lamotrigine].
    Presse medicale (Paris, France : 1983), 2001, Jun-30, Volume: 30, Issue:22

    Topics: Analgesics; Cerebrospinal Fluid Rhinorrhea; Conjunctival Diseases; Female; Functional Laterality; He

2001
Anticonvulsants-induced chorea: a role for pharmacodynamic drug interaction?
    Seizure, 2001, Volume: 10, Issue:8

    Topics: Anticonvulsants; Child, Preschool; Chorea; Drug Synergism; Drug Therapy, Combination; Dyskinesia, Dr

2001