lamotrigine has been researched along with Stroke in 21 studies
Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lamotrigine 200 mg/d reduced the median pain score to 5, compared to 7 during placebo (p = 0." | 9.09 | Lamotrigine for central poststroke pain: a randomized controlled trial. ( Andersen, G; Gottrup, H; Jensen, TS; Kristensen, BT; Vestergaard, K, 2001) |
| "The mood stabilizers lithium, valproate and lamotrigine are traditionally used to treat bipolar disorder." | 8.87 | Beneficial effects of mood stabilizers lithium, valproate and lamotrigine in experimental stroke models. ( Chuang, DM; Fessler, EB; Wang, ZF, 2011) |
| "We sought to explore the effects of sodium valproate combined with lamotrigine on quality of life and serum inflammatory factors in patients with poststroke secondary epilepsy." | 7.96 | Effects of Sodium Valproate Combined with Lamotrigine on Quality of Life and Serum Inflammatory Factors in Patients with Poststroke Secondary Epilepsy. ( Guo, D; Hao, F; Li, X; Liu, X; Sun, J; Tang, W; Tao, S, 2020) |
| " The aim of the present study was to evaluate lamotrigine (LTG), an antiepileptic that inhibits presynaptic sodium and voltage-sensitive calcium channels, as a potential stroke resuscitation agent in the rat." | 7.71 | Anticonvulsant lamotrigine administered on reperfusion fails to improve experimental stroke outcomes. ( DeVries, AC; Hurn, PD; Klaus, JA; Shaivitz, AB; Traystman, RJ, 2001) |
| "Levetiracetam (LEV) is an AED that is neuroprotective in various neurologic disorders." | 5.51 | Levetiracetam administration is correlated with lower mortality in patients with mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes: a retrospective study. ( Bao, XH; Wang, ZX; Xiong, H; Yuan, Y; Zhang, X; Zhang, Z; Zhao, DH; Zhao, XT, 2019) |
| "Lamotrigine 200 mg/d reduced the median pain score to 5, compared to 7 during placebo (p = 0." | 5.09 | Lamotrigine for central poststroke pain: a randomized controlled trial. ( Andersen, G; Gottrup, H; Jensen, TS; Kristensen, BT; Vestergaard, K, 2001) |
| "The mood stabilizers lithium, valproate and lamotrigine are traditionally used to treat bipolar disorder." | 4.87 | Beneficial effects of mood stabilizers lithium, valproate and lamotrigine in experimental stroke models. ( Chuang, DM; Fessler, EB; Wang, ZF, 2011) |
| "We sought to explore the effects of sodium valproate combined with lamotrigine on quality of life and serum inflammatory factors in patients with poststroke secondary epilepsy." | 3.96 | Effects of Sodium Valproate Combined with Lamotrigine on Quality of Life and Serum Inflammatory Factors in Patients with Poststroke Secondary Epilepsy. ( Guo, D; Hao, F; Li, X; Liu, X; Sun, J; Tang, W; Tao, S, 2020) |
| "Use of carbamazepine and valproic acid, but not lithium and lamotrigine, is associated with increased risk of stroke in patients with bipolar disorder." | 3.91 | Mood stabilisers and risk of stroke in bipolar disorder. ( Chang, CK; Chen, CC; Chen, PH; Kuo, CJ; Pan, CH; Su, SS; Tsai, SY, 2019) |
| "Lamotrigine and levetiracetam have higher retention rates than carbamazepine in poststroke epilepsy." | 3.91 | Retention rate of first antiepileptic drug in poststroke epilepsy: A nationwide study. ( Åsberg, S; Kumlien, E; Larsson, D; Zelano, J, 2019) |
| " The past medical history of the patient was significant for post-stroke epilepsy for which she was on oxcarbazepine." | 3.88 | Lesson of the month 1: To stop a fit, but swinging low. ( Agrawal, A; Ogbebor, O; Yegneswaran, B, 2018) |
| " The aim of the present study was to evaluate lamotrigine (LTG), an antiepileptic that inhibits presynaptic sodium and voltage-sensitive calcium channels, as a potential stroke resuscitation agent in the rat." | 3.71 | Anticonvulsant lamotrigine administered on reperfusion fails to improve experimental stroke outcomes. ( DeVries, AC; Hurn, PD; Klaus, JA; Shaivitz, AB; Traystman, RJ, 2001) |
| "Specific antiseizure medications (ASM) would improve the outcome in post-stroke epilepsy (PSE)." | 1.72 | Efficacy and safety of antiseizure medication in post-stroke epilepsy. ( Groppa, S; Klimpe, S; Sandner, K; Stuckrad-Barre, SV; Uphaus, T; Winter, Y, 2022) |
| "Carbamazepine was the second most common drug followed by lamotrigine and valproic acid." | 1.62 | Post-stroke epilepsy and antiepileptic drug use in men and women. ( Linnér, L; Loikas, D; Sundström, A; von Euler, M; Wettermark, B, 2021) |
| "Levetiracetam (LEV) is an AED that is neuroprotective in various neurologic disorders." | 1.51 | Levetiracetam administration is correlated with lower mortality in patients with mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes: a retrospective study. ( Bao, XH; Wang, ZX; Xiong, H; Yuan, Y; Zhang, X; Zhang, Z; Zhao, DH; Zhao, XT, 2019) |
| "Because chronic treatment with migraine prophylactic drugs suppresses SD susceptibility, we tested whether migraine prophylaxis can also suppress ischemic depolarizations and improve stroke outcome." | 1.42 | Migraine prophylaxis, ischemic depolarizations, and stroke outcomes in mice. ( Ayata, C; Can, A; Daneshmand, A; Eikermann-Haerter, K; Ferrari, MD; Lee, JH; Sengul, B; van den Maagdenberg, AM; Wei, Y; Yalcin, N; Yu, ES; Zheng, Y, 2015) |
| "She was diagnosed with left frontal lobe epilepsy, and a lamotrigine regimen was initiated." | 1.40 | Seizure freedom after lamotrigine rash: a peculiar phenomenon in epilepsy. ( Iwasaki, M; Jin, K; Kakisaka, Y; Kato, K; Nakasato, N, 2014) |
| "Sipatrigine produced no increase in paired-pulse facilitation, suggesting that the modulation of a postsynaptic site was the main pharmacological effect of this agent." | 1.31 | Electrophysiology of sipatrigine: a lamotrigine derivative exhibiting neuroprotective effects. ( Bernardi, G; Calabresi, P; Centonze, D; Giacomini, P; Hainsworth, AH; Leach, MJ; Marfia, GA; Saulle, E; Spadoni, F; Stefani, A, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (23.81) | 29.6817 |
| 2010's | 11 (52.38) | 24.3611 |
| 2020's | 5 (23.81) | 2.80 |
| Authors | Studies |
|---|---|
| Anger, T | 1 |
| Madge, DJ | 1 |
| Mulla, M | 1 |
| Riddall, D | 1 |
| Larsson, D | 2 |
| Baftiu, A | 1 |
| Johannessen Landmark, C | 1 |
| von Euler, M | 2 |
| Kumlien, E | 2 |
| Åsberg, S | 2 |
| Zelano, J | 2 |
| Winter, Y | 1 |
| Uphaus, T | 1 |
| Sandner, K | 1 |
| Klimpe, S | 1 |
| Stuckrad-Barre, SV | 1 |
| Groppa, S | 1 |
| Tao, S | 1 |
| Sun, J | 1 |
| Hao, F | 1 |
| Tang, W | 1 |
| Li, X | 2 |
| Guo, D | 1 |
| Liu, X | 2 |
| Ramey, P | 1 |
| Osborn, M | 1 |
| Kirshner, H | 1 |
| Abou-Khalil, B | 1 |
| Loikas, D | 1 |
| Linnér, L | 1 |
| Sundström, A | 1 |
| Wettermark, B | 1 |
| Ogbebor, O | 1 |
| Agrawal, A | 1 |
| Yegneswaran, B | 1 |
| Samsonia, M | 1 |
| Kandelaki, M | 1 |
| Baratashvili, N | 1 |
| Chen, PH | 1 |
| Tsai, SY | 1 |
| Pan, CH | 1 |
| Chang, CK | 1 |
| Su, SS | 1 |
| Chen, CC | 1 |
| Kuo, CJ | 1 |
| Zhang, Z | 1 |
| Zhao, DH | 1 |
| Zhao, XT | 1 |
| Zhang, X | 1 |
| Xiong, H | 1 |
| Bao, XH | 1 |
| Yuan, Y | 1 |
| Wang, ZX | 1 |
| Ozudogru, S | 1 |
| Loucao, S | 1 |
| Rauf, A | 1 |
| Cortez, M | 1 |
| Kakisaka, Y | 1 |
| Jin, K | 1 |
| Kato, K | 1 |
| Iwasaki, M | 1 |
| Nakasato, N | 1 |
| Eikermann-Haerter, K | 1 |
| Lee, JH | 1 |
| Yalcin, N | 1 |
| Yu, ES | 1 |
| Daneshmand, A | 1 |
| Wei, Y | 1 |
| Zheng, Y | 1 |
| Can, A | 1 |
| Sengul, B | 1 |
| Ferrari, MD | 1 |
| van den Maagdenberg, AM | 1 |
| Ayata, C | 1 |
| Aebischer, B | 1 |
| Elsig, S | 1 |
| Taeymans, J | 1 |
| Pomp, S | 1 |
| Kuhness, D | 1 |
| Barcaro, G | 1 |
| Sementa, L | 1 |
| Mankad, V | 1 |
| Fortunelli, A | 1 |
| Sterrer, M | 1 |
| Netzer, FP | 1 |
| Surnev, S | 1 |
| Schmieder, AH | 1 |
| Caruthers, SD | 1 |
| Keupp, J | 1 |
| Wickline, SA | 1 |
| Lanza, GM | 1 |
| Lowe, J | 1 |
| Wodarcyk, AJ | 1 |
| Floyd, KT | 1 |
| Rastogi, N | 1 |
| Schultz, EJ | 1 |
| Swager, SA | 1 |
| Chadwick, JA | 1 |
| Tran, T | 1 |
| Raman, SV | 1 |
| Janssen, PM | 1 |
| Rafael-Fortney, JA | 1 |
| Alcalay, RN | 1 |
| Levy, OA | 1 |
| Wolf, P | 1 |
| Oliva, P | 1 |
| Zhang, XK | 1 |
| Waters, CH | 1 |
| Fahn, S | 1 |
| Kang, U | 1 |
| Liong, C | 1 |
| Ford, B | 1 |
| Mazzoni, P | 1 |
| Kuo, S | 1 |
| Johnson, A | 1 |
| Xiong, L | 1 |
| Rouleau, GA | 1 |
| Chung, W | 1 |
| Marder, KS | 1 |
| Gan-Or, Z | 1 |
| Kamei, K | 1 |
| Terao, T | 1 |
| Katayama, Y | 1 |
| Hatano, K | 1 |
| Kodama, K | 1 |
| Shirahama, M | 1 |
| Sakai, A | 1 |
| Hirakawa, H | 1 |
| Mizokami, Y | 1 |
| Shiotsuki, I | 1 |
| Ishii, N | 1 |
| Inoue, Y | 1 |
| Akboga, MK | 1 |
| Yayla, C | 1 |
| Balci, KG | 1 |
| Ozeke, O | 1 |
| Maden, O | 1 |
| Kisacik, H | 1 |
| Temizhan, A | 1 |
| Aydogdu, S | 1 |
| Zhu, J | 2 |
| Ying, SH | 1 |
| Feng, MG | 1 |
| Zhang, XG | 1 |
| Li, H | 1 |
| Wang, L | 1 |
| Hao, YY | 1 |
| Liang, GD | 1 |
| Ma, YH | 1 |
| Yang, GS | 1 |
| Hu, JH | 1 |
| Pfeifer, L | 1 |
| Goertz, RS | 1 |
| Neurath, MF | 1 |
| Strobel, D | 1 |
| Wildner, D | 1 |
| Lin, JT | 1 |
| Yang, XN | 1 |
| Zhong, WZ | 1 |
| Liao, RQ | 1 |
| Dong, S | 1 |
| Nie, Q | 1 |
| Weng, SX | 1 |
| Fang, XJ | 1 |
| Zheng, JY | 1 |
| Wu, YL | 1 |
| Řezanka, T | 1 |
| Kaineder, K | 1 |
| Mezricky, D | 1 |
| Řezanka, M | 1 |
| Bišová, K | 1 |
| Zachleder, V | 1 |
| Vítová, M | 1 |
| Rinker, JA | 1 |
| Marshall, SA | 1 |
| Mazzone, CM | 1 |
| Lowery-Gionta, EG | 1 |
| Gulati, V | 1 |
| Pleil, KE | 1 |
| Kash, TL | 1 |
| Navarro, M | 1 |
| Thiele, TE | 1 |
| Zhang, Y | 1 |
| Huang, Y | 1 |
| Jin, Z | 1 |
| Li, B | 1 |
| Xu, P | 1 |
| Huang, P | 1 |
| Liu, C | 1 |
| Fokdal, L | 1 |
| Sturdza, A | 1 |
| Mazeron, R | 1 |
| Haie-Meder, C | 1 |
| Tan, LT | 1 |
| Gillham, C | 1 |
| Šegedin, B | 1 |
| Jürgenliemk-Schultz, I | 1 |
| Kirisits, C | 1 |
| Hoskin, P | 1 |
| Pötter, R | 1 |
| Lindegaard, JC | 1 |
| Tanderup, K | 1 |
| Levin, DE | 1 |
| Schmitz, AJ | 1 |
| Hines, SM | 1 |
| Hines, KJ | 1 |
| Tucker, MJ | 1 |
| Brewer, SH | 1 |
| Fenlon, EE | 1 |
| Álvarez-Pérez, S | 1 |
| Blanco, JL | 1 |
| Peláez, T | 1 |
| Martínez-Nevado, E | 1 |
| García, ME | 1 |
| Puckerin, AA | 1 |
| Chang, DD | 1 |
| Subramanyam, P | 1 |
| Colecraft, HM | 1 |
| Dogan, H | 1 |
| Coteli, E | 1 |
| Karatas, F | 1 |
| Ceylan, O | 1 |
| Sahin, MD | 1 |
| Akdamar, G | 1 |
| Kryczyk, A | 1 |
| Żmudzki, P | 1 |
| Hubicka, U | 1 |
| Giovannelli, D | 1 |
| Chung, M | 1 |
| Staley, J | 1 |
| Starovoytov, V | 1 |
| Le Bris, N | 1 |
| Vetriani, C | 1 |
| Chen, W | 1 |
| Wu, L | 1 |
| Shen, Y | 1 |
| Liang, Y | 1 |
| Tan, H | 1 |
| Yang, Y | 1 |
| Liu, Q | 1 |
| Wang, M | 1 |
| Liu, L | 1 |
| Wang, X | 1 |
| Liu, B | 1 |
| Liu, GH | 1 |
| Zhu, YJ | 1 |
| Wang, JP | 1 |
| Che, JM | 1 |
| Chen, QQ | 1 |
| Chen, Z | 1 |
| Maucksch, U | 1 |
| Runge, R | 1 |
| Wunderlich, G | 1 |
| Freudenberg, R | 1 |
| Naumann, A | 1 |
| Kotzerke, J | 1 |
| Tessitore, E | 1 |
| Ramlawi, M | 1 |
| Tobler, O | 1 |
| Sunthorn, H | 1 |
| Wang, ZF | 1 |
| Fessler, EB | 1 |
| Chuang, DM | 1 |
| Yen, HL | 1 |
| Chan, W | 1 |
| Calabresi, P | 1 |
| Stefani, A | 1 |
| Marfia, GA | 1 |
| Hainsworth, AH | 1 |
| Centonze, D | 1 |
| Saulle, E | 1 |
| Spadoni, F | 1 |
| Leach, MJ | 1 |
| Giacomini, P | 1 |
| Bernardi, G | 1 |
| Vestergaard, K | 1 |
| Andersen, G | 1 |
| Gottrup, H | 1 |
| Kristensen, BT | 1 |
| Jensen, TS | 1 |
| Traystman, RJ | 1 |
| Klaus, JA | 1 |
| DeVries, AC | 1 |
| Shaivitz, AB | 1 |
| Hurn, PD | 1 |
3 reviews available for lamotrigine and Stroke
| Article | Year |
|---|---|
Medicinal chemistry of neuronal voltage-gated sodium channel blockers.
Topics: Amyotrophic Lateral Sclerosis; Analgesics; Anticonvulsants; Epilepsy; Humans; Ion Channel Gating; Mo | 2001 |
Topics: AC133 Antigen; Acenaphthenes; Acer; Acrosome Reaction; Adult; Agaricales; Aged; Aged, 80 and over; A | 2016 |
Beneficial effects of mood stabilizers lithium, valproate and lamotrigine in experimental stroke models.
Topics: Animals; Antipsychotic Agents; Bipolar Disorder; Disease Models, Animal; Humans; Lamotrigine; Lithiu | 2011 |
1 trial available for lamotrigine and Stroke
| Article | Year |
|---|---|
Lamotrigine for central poststroke pain: a randomized controlled trial.
Topics: Adult; Aged; Analysis of Variance; Double-Blind Method; Female; Humans; Lamotrigine; Male; Middle Ag | 2001 |
17 other studies available for lamotrigine and Stroke
| Article | Year |
|---|---|
Association Between Antiseizure Drug Monotherapy and Mortality for Patients With Poststroke Epilepsy.
Topics: Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Cardiovascular Diseases; Cohort Studies; Dr | 2022 |
Efficacy and safety of antiseizure medication in post-stroke epilepsy.
Topics: Anticonvulsants; Epilepsies, Partial; Epilepsy; Humans; Lacosamide; Lamotrigine; Levetiracetam; Seiz | 2022 |
Effects of Sodium Valproate Combined with Lamotrigine on Quality of Life and Serum Inflammatory Factors in Patients with Poststroke Secondary Epilepsy.
Topics: Aged; Anticonvulsants; Biomarkers; Brain; Case-Control Studies; Down-Regulation; Drug Therapy, Combi | 2020 |
Misdiagnosis of lamotrigine toxicity as posterior circulation transient ischemic attack or stroke.
Topics: Adult; Aged; Anticonvulsants; Ataxia; Diagnostic Errors; Dizziness; Dose-Response Relationship, Drug | 2020 |
Post-stroke epilepsy and antiepileptic drug use in men and women.
Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Lamotrigin | 2021 |
Lesson of the month 1: To stop a fit, but swinging low.
Topics: Accidental Falls; Aged; Anticonvulsants; Drug Substitution; Epilepsy; Female; Humans; Lamotrigine; O | 2018 |
[EVALUATION OF NEUROPROTECTIVE ACTIVITY OF COMPLEX IMPACT OF MAGNESIUM OF SULFATE, LAMOTRYGINE AND N-ACETYLCYSTEINE UNDER CONDITIONS OF COMBINED NORMOBARIC HYPOXIA WITH LIGATION OF RIGHT CAROTID ARTERY IN RATS].
Topics: Acetylcysteine; Administration, Oral; Animals; Animals, Outbred Strains; Brain Ischemia; Carotid Art | 2018 |
Mood stabilisers and risk of stroke in bipolar disorder.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Carbamazepine; Cross-O | 2019 |
Retention rate of first antiepileptic drug in poststroke epilepsy: A nationwide study.
Topics: Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Lamotrigine; Leve | 2019 |
Levetiracetam administration is correlated with lower mortality in patients with mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes: a retrospective study.
Topics: Acidosis, Lactic; Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Female; Human | 2019 |
Post-stroke short-lasting unilateral neuralgiform headache attacks with autonomic symptoms (SUNA): response to lamotrigine and sphenopalatine ganglion block.
Topics: Anticonvulsants; Combined Modality Therapy; Headache; Humans; Lamotrigine; Male; Middle Aged; Spheno | 2019 |
Seizure freedom after lamotrigine rash: a peculiar phenomenon in epilepsy.
Topics: Anticonvulsants; Drug Eruptions; Epilepsy, Frontal Lobe; Exanthema; Female; Humans; Lamotrigine; Mid | 2014 |
Migraine prophylaxis, ischemic depolarizations, and stroke outcomes in mice.
Topics: Animals; Anticonvulsants; Brain Ischemia; Calcium Channels, N-Type; Chemoprevention; Cortical Spread | 2015 |
Brugada Pattern Caused by a Flecainide Overdose.
Topics: Atrial Fibrillation; Bipolar Disorder; Brugada Syndrome; Consciousness Disorders; Drug Overdose; Ele | 2017 |
An East-West approach to the management of central post-stroke pain.
Topics: Acetates; Acupuncture; Aged; Amines; Amitriptyline; Analgesics, Opioid; Antidepressive Agents, Secon | 2003 |
Electrophysiology of sipatrigine: a lamotrigine derivative exhibiting neuroprotective effects.
Topics: Action Potentials; Animals; Anticonvulsants; Brain Chemistry; Calcium Channels; Corpus Striatum; Epi | 2000 |
Anticonvulsant lamotrigine administered on reperfusion fails to improve experimental stroke outcomes.
Topics: Animals; Anticonvulsants; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug | 2001 |