lamotrigine has been researched along with Stevens-Johnson Syndrome in 108 studies
Stevens-Johnson Syndrome: Rare cutaneous eruption characterized by extensive KERATINOCYTE apoptosis resulting in skin detachment with mucosal involvement. It is often provoked by the use of drugs (e.g., antibiotics and anticonvulsants) or associated with PNEUMONIA, MYCOPLASMA. It is considered a continuum of Toxic Epidermal Necrolysis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are fatal adverse cutaneous drug reactions which may be induced by phenytoin (PHT) or lamotrigine (LTG)." | 8.91 | HLA-B*1502 increases the risk of phenytoin or lamotrigine induced Stevens-Johnson Syndrome/toxic epidermal necrolysis: evidence from a meta-analysis of nine case-control studies. ( Huo, J; Li, X; Mei, S; Wang, J; Yu, K; Zhao, Z; Zhu, Y, 2015) |
| "Despite several studies investigating the association between the human leukocyte antigen HLA-B*1502 allele and lamotrigine-induced Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) in Han Chinese subjects, the relationship remains unclear." | 8.91 | Association of HLA-B*1502 allele with lamotrigine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Han Chinese subjects: a meta-analysis. ( Liao, WP; Long, YS; Min, FL; Shi, YW; Zeng, T, 2015) |
| "To evaluate the efficacy of lamotrigine for treatment of short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT) syndrome." | 8.87 | The role of lamotrigine in the treatment of short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing syndrome. ( Karpinski, JP; Rosselli, JL, 2011) |
| ", carbamazepine (CBZ)- and lamotrigine (LTG)-induced Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN)." | 8.31 | Association of Human Leukocyte Antigen Alleles with Carbamazepine- or Lamotrigine-Induced Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in an Iranian Population: A Case-control Study. ( Asadi-Pooya, AA; Dastgheib, L; Gharesi-Fard, B; Hadibarhaghtalab, M; Namjoo, S; Rostami, F; Tahmasebi, F, 2023) |
| "Previous studies have found an association between HLA-B*1502 allele and lamotrigine-induced Stevens-Johnson syndrome (SJS)/ toxic epidermal necrosis (TEN) spectrum in Han Chinese populations." | 8.02 | Investigating the association of Lamotrigine and Phenytoin-induced Stevens-Johnson syndrome/Toxic Epidermal Necrolysis with HLA-B*1502 in Iranian population. ( Afkhami Ardakani, S; Eslahi, A; Farrokhi, S; Jarahi, L; Kiafar, B; Mojarad, M; Mortezaee, R; Sabourirad, S; Shahrokhi, Y, 2021) |
| "The purpose of this study is to compare the severity of chronic ocular complications of Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) induced by lamotrigine (LT) vs." | 8.02 | Chronic ocular complications in lamotrigine vs. trimethoprim-sulfamethoxazole induced Stevens-Johnson syndrome/toxic epidermal necrolysis. ( Chodosh, J; Kwan, J; Rashad, R; Saeed, HN; Saeed, S; Shanbhag, SS, 2021) |
| " After a lamotrigine-induced Stevens-Johnson syndrome (SJS) occurred, she presented with total collapse of the right lung on admission, which was subsequently complicated by a pneumothorax during conservative treatment, but with the re-expansion of the right upper lobe after intervention." | 7.81 | Bronchiolitis obliterans complicating a pneumothorax after Stevens-Johnson syndrome induced by lamotrigine. ( Cheng, QS; Li, XF; Lu, Q; Ni, YF; Wang, WP; Wei, YN, 2015) |
| "In a trial including 38 children, lamotrigine, which had to be introduced very gradually in order to reduce the risk of potentially severe skin reactions, took longer than valproic acid to control typical absence seizures." | 7.75 | Lamotrigine and absence seizures: new indication. Try valproic acid first. ( , 2009) |
| "Lamotrigine (LTG) has shown to confer broad-spectrum, well-tolerated control of epilepsy." | 7.75 | Efficacy and safety of lamotrigine monotherapy in children and adolescents with epilepsy. ( Hardison, HH; Khurana, DS; Kothare, SV; Legido, A; Marks, HG; Melvin, JJ; Piñol-Ripoll, G; Valencia, I, 2009) |
| "We describe a patient originally suffering from a depressive syndrome who developed Stevens-Johnson syndrome after 12 days of treatment with lamotrigine." | 7.75 | Neopterin and C-reactive protein in the course of Stevens-Johnson syndrome: report of a case. ( Bertram, L; Grözinger, M; Liss, Y, 2009) |
| "A case of lamotrigine-induced Stevens-Johnson syndrome (SJS) is reported." | 7.74 | Lamotrigine-induced Stevens-Johnson syndrome. ( Charneski, L; Hilas, O, 2007) |
| "Stevens-Johnson syndrome is a severe and potentially life-threatening cutaneous reaction associated with lamotrigine." | 7.74 | Concomitant use of lamotrigine and aripiprazole increases risk of Stevens-Johnson syndrome? ( Chen, CH; Chen, SJ; Lin, CC; Shen, YC, 2007) |
| "To examine the safety of lamotrigine (LTG) used in general practice to treat epilepsy." | 7.69 | Safety of long-term lamotrigine in epilepsy. ( Freemantle, SN; Mackay, FJ; Mann, RD; Pearce, GL; Wilton, LV, 1997) |
| " To facilitate this, manufacturers have developed a strict re-challenge dosing regimen to facilitate successful reintroduction of lamotrigine." | 6.72 | Lamotrigine and Stevens-Johnson Syndrome Prevention. ( Crane, E; Edinoff, AN; Fitz-Gerald, MJ; Gennuso, SA; Kaye, AD; Kaye, AM; Kaye, JS; Kaye, RJ; Lewis, K; Nguyen, LH; Pierre, SS; Urits, I; Varrassi, G; Viswanath, O, 2021) |
| "Lamotrigine is an antiepileptic drug that has been widely used for epilepsy, as a mood stabilizer (for type 1 bipolar disorder) and in the management of neuropathic pain, it is used both in monotherapy and in complementary therapy." | 5.56 | Lamotrigine and its relationship with Stevens-Johnson syndrome and toxic epidermal necrolysis ( Domínguez-Cherit, J; Méndez-Flores, S; Rodríguez-Chávez, Y; Velázquez-Cárcamo, EA, 2020) |
| "Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare but fatal adverse mucocutaneous reactions to certain drugs." | 5.42 | Clinical features of and genetic predisposition to drug-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in a single Korean tertiary institution patients-investigating the relation between the HLA -B*4403 allele and lamotrigine. ( Kim, SR; Koh, BS; Lee, JH; Leem, DW; Moon, IJ; Park, HJ; Park, JW; Park, KH, 2015) |
| "Lamotrigine (LTG) is a novel antiepileptic drug effective in partial and generalized seizures." | 5.31 | Stevens-Johnson syndrome associated with concomitant use of lamotrigine and valproic acid. ( Karaduman, A; Yalçin, B, 2000) |
| "Lamotrigine is a new anticonvulsant belonging to the triazine family." | 5.30 | [Lyell syndrome and Stevens-Johnson syndrome caused by lamotrigine]. ( Barzegar, C; Bocquet, H; Bressieux, JM; Farmer, M; Jullien, M; Revuz, J; Roujeau, JC; Soto, B, 1999) |
| "Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are fatal adverse cutaneous drug reactions which may be induced by phenytoin (PHT) or lamotrigine (LTG)." | 4.91 | HLA-B*1502 increases the risk of phenytoin or lamotrigine induced Stevens-Johnson Syndrome/toxic epidermal necrolysis: evidence from a meta-analysis of nine case-control studies. ( Huo, J; Li, X; Mei, S; Wang, J; Yu, K; Zhao, Z; Zhu, Y, 2015) |
| "Despite several studies investigating the association between the human leukocyte antigen HLA-B*1502 allele and lamotrigine-induced Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) in Han Chinese subjects, the relationship remains unclear." | 4.91 | Association of HLA-B*1502 allele with lamotrigine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Han Chinese subjects: a meta-analysis. ( Liao, WP; Long, YS; Min, FL; Shi, YW; Zeng, T, 2015) |
| "We systematically reviewed and analyzed published patients with Stevens-Johnson syndrome (SJS) or toxic epidermal necrolysis (TEN) associated with lamotrigine therapy to identify characteristics of these reactions." | 4.91 | Lamotrigine-induced severe cutaneous adverse reaction: Update data from 1999-2014. ( Huang, XS; Lang, SY; Lv, B; Tian, CL; Wang, HF; Wang, XQ; Yu, SY; Zhang, JT; Zhang, X, 2015) |
| "To evaluate the efficacy of lamotrigine for treatment of short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT) syndrome." | 4.87 | The role of lamotrigine in the treatment of short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing syndrome. ( Karpinski, JP; Rosselli, JL, 2011) |
| "We systematically reviewed and analyzed published and unpublished cases of Stevens-Johnson syndrome (SJS), or toxic epidermal necrolysis (TEN) associated with lamotrigine (LTG) therapy to identify characteristics of these reactions." | 4.80 | Lamotrigine-induced severe cutaneous adverse reactions. ( Schlienger, RG; Shapiro, LE; Shear, NH, 1998) |
| ", carbamazepine (CBZ)- and lamotrigine (LTG)-induced Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN)." | 4.31 | Association of Human Leukocyte Antigen Alleles with Carbamazepine- or Lamotrigine-Induced Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in an Iranian Population: A Case-control Study. ( Asadi-Pooya, AA; Dastgheib, L; Gharesi-Fard, B; Hadibarhaghtalab, M; Namjoo, S; Rostami, F; Tahmasebi, F, 2023) |
| "The purpose of this study is to compare the severity of chronic ocular complications of Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) induced by lamotrigine (LT) vs." | 4.02 | Chronic ocular complications in lamotrigine vs. trimethoprim-sulfamethoxazole induced Stevens-Johnson syndrome/toxic epidermal necrolysis. ( Chodosh, J; Kwan, J; Rashad, R; Saeed, HN; Saeed, S; Shanbhag, SS, 2021) |
| "Previous studies have found an association between HLA-B*1502 allele and lamotrigine-induced Stevens-Johnson syndrome (SJS)/ toxic epidermal necrosis (TEN) spectrum in Han Chinese populations." | 4.02 | Investigating the association of Lamotrigine and Phenytoin-induced Stevens-Johnson syndrome/Toxic Epidermal Necrolysis with HLA-B*1502 in Iranian population. ( Afkhami Ardakani, S; Eslahi, A; Farrokhi, S; Jarahi, L; Kiafar, B; Mojarad, M; Mortezaee, R; Sabourirad, S; Shahrokhi, Y, 2021) |
| "We describe the case history of a 9-year-old boy who developed Stevens-Johnson syndrome (SJS) following concomitant use of valproic acid and lamotrigine." | 3.85 | Stevens - Johnson Syndrome Induced by Combination of Lamotrigine and Valproic Acid in a 9-Year-Old Boy. ( Buckley, D; Maduemem, K; O'Neill, T; Vatca, A, 2017) |
| " After a lamotrigine-induced Stevens-Johnson syndrome (SJS) occurred, she presented with total collapse of the right lung on admission, which was subsequently complicated by a pneumothorax during conservative treatment, but with the re-expansion of the right upper lobe after intervention." | 3.81 | Bronchiolitis obliterans complicating a pneumothorax after Stevens-Johnson syndrome induced by lamotrigine. ( Cheng, QS; Li, XF; Lu, Q; Ni, YF; Wang, WP; Wei, YN, 2015) |
| " We present a 12-year-old girl with epilepsy who developed TEN after about 14 days of lamotrigine treatment." | 3.79 | A lamotrigine induced toxic epidermal necrolysis in a child. ( Altun, F; Bilgili, SG; Bulut, G; Burakgazi, AZ; Calka, O; Karadag, AS, 2013) |
| "We describe a patient originally suffering from a depressive syndrome who developed Stevens-Johnson syndrome after 12 days of treatment with lamotrigine." | 3.75 | Neopterin and C-reactive protein in the course of Stevens-Johnson syndrome: report of a case. ( Bertram, L; Grözinger, M; Liss, Y, 2009) |
| "In a trial including 38 children, lamotrigine, which had to be introduced very gradually in order to reduce the risk of potentially severe skin reactions, took longer than valproic acid to control typical absence seizures." | 3.75 | Lamotrigine and absence seizures: new indication. Try valproic acid first. ( , 2009) |
| "Lamotrigine (LTG) has shown to confer broad-spectrum, well-tolerated control of epilepsy." | 3.75 | Efficacy and safety of lamotrigine monotherapy in children and adolescents with epilepsy. ( Hardison, HH; Khurana, DS; Kothare, SV; Legido, A; Marks, HG; Melvin, JJ; Piñol-Ripoll, G; Valencia, I, 2009) |
| "A previous study conducted in Taiwan found a 100% association between HLA-B*1502 allele and carbamazepine-induced Stevens-Johnson syndrome (SJS) in Han Chinese subjects, with an extremely high odds ratio compared with carbamazepine-tolerant subjects (odds ratio = 2,504)." | 3.74 | Association between HLA-B*1502 allele and antiepileptic drug-induced cutaneous reactions in Han Chinese. ( Baum, L; Cheng, AS; Kwan, P; Lau, KM; Man, CB; Ng, MH; Yu, E, 2007) |
| "Stevens-Johnson syndrome is a severe and potentially life-threatening cutaneous reaction associated with lamotrigine." | 3.74 | Concomitant use of lamotrigine and aripiprazole increases risk of Stevens-Johnson syndrome? ( Chen, CH; Chen, SJ; Lin, CC; Shen, YC, 2007) |
| " We present a 12 years old female who was a known case of idiopathic generalized tonic-clonic convulsion and presented with fever, diarrhea and generalized erythematous eruption after 2 weeks of being under treatment with maintenance doses of Lamotrigine (LTG) and Valproate (VPA)." | 3.74 | Intravenous immunoglobulin in the treatment of lamotrigine- induced toxic epidermal necrolysis. ( Inaloo, S; Serati Shirazi, Z, 2008) |
| "A case of lamotrigine-induced Stevens-Johnson syndrome (SJS) is reported." | 3.74 | Lamotrigine-induced Stevens-Johnson syndrome. ( Charneski, L; Hilas, O, 2007) |
| "Across a range of assumptions used, the risk of hospitalization for Stevens-Johnson syndrome or toxic epidermal necrolysis in new users is low for carbamazepine, lamotrigine, phenytoin, phenobarbital, and valproic acid." | 3.73 | Risk of Stevens-Johnson syndrome and toxic epidermal necrolysis in new users of antiepileptics. ( Messenheimer, J; Mockenhaupt, M; Schlingmann, J; Tennis, P, 2005) |
| "A 43-year-old man developed a skin eruption characterized by 'macules with blisters' typical to Stevens-Johnson syndrome, as well as erosions of the lips and buccal mucosa, 2 weeks after he had started treatment with lamotrigine." | 3.73 | Drug Rash with eosinophilia and systemic symptoms versus Stevens-Johnson Syndrome--a case that indicates a stumbling block in the current classification. ( Davidovici, B; Mahlab, K; Matz, H; Orion, E; Sthoeger, ZM; Wolf, R, 2006) |
| "A 10-year-old girl developed a progressive rash and high fever more than a month after the start of lamotrigine as add-on medication for therapy-resistant epilepsy." | 3.72 | [Toxic epidermal necrolysis due to lamotrigine]. ( Beerhorst, K; Renier, WO, 2003) |
| "During lamotrigine's premarketing clinical trials, the manufacturer reported several cases of Stevens-Johnson syndrome and TEN." | 3.69 | Suspected lamotrigine-induced toxic epidermal necrolysis. ( Chaffin, JJ; Davis, SM, 1997) |
| "To examine the safety of lamotrigine (LTG) used in general practice to treat epilepsy." | 3.69 | Safety of long-term lamotrigine in epilepsy. ( Freemantle, SN; Mackay, FJ; Mann, RD; Pearce, GL; Wilton, LV, 1997) |
| " To facilitate this, manufacturers have developed a strict re-challenge dosing regimen to facilitate successful reintroduction of lamotrigine." | 2.72 | Lamotrigine and Stevens-Johnson Syndrome Prevention. ( Crane, E; Edinoff, AN; Fitz-Gerald, MJ; Gennuso, SA; Kaye, AD; Kaye, AM; Kaye, JS; Kaye, RJ; Lewis, K; Nguyen, LH; Pierre, SS; Urits, I; Varrassi, G; Viswanath, O, 2021) |
| "Serious drug eruptions associated with lamotrigine were rare." | 2.41 | Rash in multicenter trials of lamotrigine in mood disorders: clinical relevance and management. ( Bowden, CL; Calabrese, JR; Frye, MA; Goldberg, JF; Goodwin, FK; Kusumakar, V; Sachs, GS; Shelton, MD; Sullivan, JR; Suppes, T, 2002) |
| "Lamotrigine (LTG) is an antiepileptic drug (AED) recently released in several countries." | 2.40 | Lamotrigine-associated rash: risk/benefit considerations in adults and children. ( Besag, FM; Brodie, MJ; Dooley, JM; Duchowny, MS; Guberman, AH; Pellock, JM; Richens, A; Stern, RS; Trevathan, E, 1999) |
| "This study was undertaken to determine the impact of dosage in new users of lamotrigine (LTG) and the concomitant intake of valproic acid (VPA) on epidermal necrolysis (EN)." | 1.91 | Effects of dosage in new users of lamotrigine inducing epidermal necrolysis: Results of the German Registry of Severe Skin Reactions. ( Diederich, S; Hemmeter, U; Mockenhaupt, M; Paulmann, M, 2023) |
| "Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis Syndrome (TEN) are rare immune-mediated diseases." | 1.62 | Toxic epidermal necrolysis and Stevens-Johnson syndrome/toxic epidermal necrolysis overlap in pediatric patients with a focus on newer antiepileptic drugs: A 25-year retrospective study at a single tertiary care center. ( Gleghorn, KL; Kelly, B; Voigt, C, 2021) |
| "Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) are the most severe cutaneous drug hypersensitivity reactions, which are unpredictable adverse drug reactions." | 1.56 | Therapeutic Effects of Mesenchymal Stem Cells on a Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis Model. ( Cho, YS; Kim, HJ; Kim, JH; Kim, TB; Kwon, HS; Kwon, OY; Moon, HB; Oh, IY; Park, SY; Seo, B; Song, WJ, 2020) |
| "Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are immune-mediated diseases characterized by an extensive loss of the epidermal skin layer, often resulting in death." | 1.56 | Antiepileptic combination therapy with Stevens-Johnson syndrome and toxic epidermal necrolysis: Analysis of a Japanese pharmacovigilance database. ( Hayashi, T; Noguchi, Y; Tachi, T; Takaoka, M; Teramachi, H, 2020) |
| "Lamotrigine is an antiepileptic drug that has been widely used for epilepsy, as a mood stabilizer (for type 1 bipolar disorder) and in the management of neuropathic pain, it is used both in monotherapy and in complementary therapy." | 1.56 | Lamotrigine and its relationship with Stevens-Johnson syndrome and toxic epidermal necrolysis ( Domínguez-Cherit, J; Méndez-Flores, S; Rodríguez-Chávez, Y; Velázquez-Cárcamo, EA, 2020) |
| "Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare but severe cutaneous adverse drug reactions." | 1.43 | Incidence, causative factors and mortality rates of Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) in northern Italy: data from the REACT registry. ( Cazzaniga, S; Citterio, A; Diphoorn, J; Gamba, C; Naldi, L; Rivolta, AL; Schroeder, J; Vighi, GD, 2016) |
| "Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are very serious forms of drug-induced cutaneous adverse reaction." | 1.43 | HLA Allele Frequencies in 5802 Koreans: Varied Allele Types Associated with SJS/TEN According to Culprit Drugs. ( Kim, DH; Kim, J; Kim, YJ; Lee, JH; Park, HJ; Park, JW; Park, KH, 2016) |
| "Lamotrigine is an anticonvulsant drug used to treat partial and generalized seizure disorders." | 1.42 | Liver dysfunction induced by systemic hypersensitivity reaction to lamotrigine: case report. ( Cho, HJ; Im, SG; Jang, SK; Jeon, DO; Lee, SJ; Oh, MJ; Park, YM; Yoo, SH, 2015) |
| "Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare but fatal adverse mucocutaneous reactions to certain drugs." | 1.42 | Clinical features of and genetic predisposition to drug-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in a single Korean tertiary institution patients-investigating the relation between the HLA -B*4403 allele and lamotrigine. ( Kim, SR; Koh, BS; Lee, JH; Leem, DW; Moon, IJ; Park, HJ; Park, JW; Park, KH, 2015) |
| " The differences in the starting dosage of LTG among the SJS/TEN, MPE, and LTG-tolerant control groups were not statistically significant." | 1.36 | Association study of lamotrigine-induced cutaneous adverse reactions and HLA-B*1502 in a Han Chinese population. ( An, DM; Hu, FY; Stefan, H; Wu, XT; Yan, B; Zhou, D, 2010) |
| "Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare but severe cutaneous adverse reactions (SCAR) related to a variety of medications." | 1.35 | Stevens-Johnson syndrome and toxic epidermal necrolysis: assessment of medication risks with emphasis on recently marketed drugs. The EuroSCAR-study. ( Bouwes Bavinck, JN; Dunant, A; Flahault, A; Halevy, S; Mockenhaupt, M; Naldi, L; Roujeau, JC; Schneck, J; Sidoroff, A; Viboud, C, 2008) |
| "Most cases of toxic epidermal necrolysis are drug induced." | 1.32 | Suspected lamotrigine-induced toxic epidermal necrolysis. ( Demiralay, E; Kilinç, M; Söğüt, A; Söğüt, AG; Uzar, H; Yilmaz, A, 2003) |
| "Sequential blood and blister fluid samples were obtained for flow cytometry and reverse transcriptase-polymerase chain reaction analyses." | 1.32 | Improvement of toxic epidermal necrolysis after the early administration of a single high dose of intravenous immunoglobulin. ( Alvarez, J; Blanca, M; Corzo, JL; Jurado, A; Mayorga, C; Posadas, S; Sanchez-Sabate, E; Torres, MJ; Vera, A, 2003) |
| "Lamotrigine (LTG) is a novel antiepileptic drug effective in partial and generalized seizures." | 1.31 | Stevens-Johnson syndrome associated with concomitant use of lamotrigine and valproic acid. ( Karaduman, A; Yalçin, B, 2000) |
| "A case of toxic epidermal necrolysis following treatment with lamotrigine is presented." | 1.30 | [Toxic epidermal necrolysis after treatment with lamotrigine]. ( Fogh, K; Zachariae, CO, 1998) |
| "Lamotrigine is a new anticonvulsant belonging to the triazine family." | 1.30 | [Lyell syndrome and Stevens-Johnson syndrome caused by lamotrigine]. ( Barzegar, C; Bocquet, H; Bressieux, JM; Farmer, M; Jullien, M; Revuz, J; Roujeau, JC; Soto, B, 1999) |
| "We report on the first fatal course of toxic epidermal necrolysis (Lyell's disease) occurring under treatment with lamotrigine, following the development of a skin rash caused by carbamazepine." | 1.29 | Fatal course of toxic epidermal necrolysis under treatment with lamotrigine. ( Berrouschot, J; Schneider, D; Sterker, M, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 18 (16.67) | 18.2507 |
| 2000's | 39 (36.11) | 29.6817 |
| 2010's | 34 (31.48) | 24.3611 |
| 2020's | 17 (15.74) | 2.80 |
| Authors | Studies |
|---|---|
| Hui, LLY | 1 |
| Loke, C | 1 |
| Aw, DCW | 1 |
| Tan, L | 1 |
| Limenta, LMG | 1 |
| Shen, M | 1 |
| Ren, EC | 1 |
| Toh, DSL | 1 |
| Lee, EJD | 1 |
| Pang, SM | 1 |
| Mortazavi, H | 1 |
| Rostami, A | 1 |
| Firooz, A | 1 |
| Esmaili, N | 1 |
| Ghiasi, M | 1 |
| Lajevardi, V | 1 |
| Amirzargar, AA | 1 |
| Sheykhi, I | 1 |
| Khamesipour, A | 1 |
| Akhdar, M | 1 |
| Almuhana, G | 1 |
| Alsalhi, A | 1 |
| Alsalhi, H | 1 |
| Al-Hoqail, IA | 1 |
| Dastgheib, L | 1 |
| Rostami, F | 1 |
| Gharesi-Fard, B | 1 |
| Asadi-Pooya, AA | 1 |
| Namjoo, S | 1 |
| Tahmasebi, F | 1 |
| Hadibarhaghtalab, M | 1 |
| Diederich, S | 1 |
| Hemmeter, U | 1 |
| Paulmann, M | 1 |
| Mockenhaupt, M | 4 |
| Das, SK | 1 |
| Sampath, A | 1 |
| Zaman, SU | 1 |
| Pati, AK | 1 |
| Atal, S | 1 |
| Saito, Y | 1 |
| Nakamura, R | 1 |
| Park, SY | 1 |
| Oh, IY | 1 |
| Kim, JH | 1 |
| Kim, HJ | 1 |
| Seo, B | 1 |
| Kwon, OY | 1 |
| Song, WJ | 1 |
| Kwon, HS | 1 |
| Cho, YS | 1 |
| Moon, HB | 1 |
| Kim, TB | 1 |
| Noguchi, Y | 1 |
| Takaoka, M | 1 |
| Hayashi, T | 1 |
| Tachi, T | 1 |
| Teramachi, H | 1 |
| Faris, J | 1 |
| Wilson, J | 1 |
| Dolman, HS | 1 |
| Isaacson, A | 1 |
| Baylor, AE | 1 |
| Tyburski, JG | 1 |
| White, MT | 1 |
| Chung, SJ | 1 |
| Ahn, KM | 1 |
| Oh, JH | 1 |
| Shim, JS | 1 |
| Park, HW | 1 |
| Jenei Kluch, L | 1 |
| Erdei, I | 1 |
| Remenyik, É | 1 |
| Surányi, É | 1 |
| Bodnár, F | 1 |
| Emri, G | 1 |
| Szegedi, A | 1 |
| Sabourirad, S | 1 |
| Mortezaee, R | 1 |
| Mojarad, M | 1 |
| Eslahi, A | 1 |
| Shahrokhi, Y | 1 |
| Kiafar, B | 1 |
| Jarahi, L | 1 |
| Afkhami Ardakani, S | 1 |
| Farrokhi, S | 1 |
| Fukasawa, T | 1 |
| Takahashi, H | 1 |
| Takahashi, K | 1 |
| Tanemura, N | 1 |
| Amagai, M | 1 |
| Urushihara, H | 1 |
| Rashad, R | 1 |
| Shanbhag, SS | 1 |
| Kwan, J | 1 |
| Chodosh, J | 1 |
| Saeed, S | 1 |
| Saeed, HN | 1 |
| Gleghorn, KL | 1 |
| Voigt, C | 1 |
| Kelly, B | 1 |
| Edinoff, AN | 1 |
| Nguyen, LH | 1 |
| Fitz-Gerald, MJ | 1 |
| Crane, E | 1 |
| Lewis, K | 1 |
| Pierre, SS | 1 |
| Kaye, AD | 1 |
| Kaye, AM | 1 |
| Kaye, JS | 1 |
| Kaye, RJ | 1 |
| Gennuso, SA | 1 |
| Varrassi, G | 1 |
| Viswanath, O | 1 |
| Urits, I | 1 |
| Velázquez-Cárcamo, EA | 1 |
| Rodríguez-Chávez, Y | 1 |
| Méndez-Flores, S | 1 |
| Domínguez-Cherit, J | 1 |
| Maduemem, K | 1 |
| Vatca, A | 1 |
| O'Neill, T | 1 |
| Buckley, D | 1 |
| Parker, G | 2 |
| Hosohata, K | 1 |
| Inada, A | 1 |
| Oyama, S | 1 |
| Niinomi, I | 1 |
| Wakabayashi, T | 1 |
| Iwanaga, K | 1 |
| Haoxiang, X | 1 |
| Xu, Y | 1 |
| Baoxi, W | 1 |
| Li, X | 1 |
| Yu, K | 1 |
| Mei, S | 1 |
| Huo, J | 1 |
| Wang, J | 1 |
| Zhu, Y | 1 |
| Zhao, Z | 1 |
| Park, HJ | 2 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Improvement and Clinical Application of a New Minimally Invasive Closed Thoracic Drainage System[NCT04143360] | 100 participants (Anticipated) | Interventional | 2020-04-30 | Not yet recruiting | |||
| The BrainDrugs-Epilepsy Study: A Prospective Open-label Cohort Precision Medicine Study in Epilepsy[NCT05450822] | 550 participants (Anticipated) | Observational | 2022-02-18 | Recruiting | |||
| A Preliminary Study of the Efficacy and Safety of Carbamazepine in Severe Liver Disease Due to Alpha-1 Antitrypsin Deficiency[NCT01379469] | Phase 2 | 20 participants (Actual) | Interventional | 2012-01-31 | Terminated | ||
| Mesenchymal Stromal Cells Treatment in Lyell Syndrome: A Pilot Phase 1-2 Open Trial[NCT04711200] | Phase 1/Phase 2 | 15 participants (Anticipated) | Interventional | 2022-09-30 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
14 reviews available for lamotrigine and Stevens-Johnson Syndrome
| Article | Year |
|---|---|
Genetic predisposition for the development of lamotrigine-induced Stevens-Johnson syndrome/toxic epidermal necrolysis: a systematic review and meta-analysis.
Topics: Anticonvulsants; Genetic Predisposition to Disease; HLA-B Antigens; Humans; Lamotrigine; Stevens-Joh | 2023 |
[Mechanisms of Severe Cutaneous Adverse Reactions and a New Treatment Strategy].
Topics: Acetaminophen; Adrenal Cortex Hormones; Allopurinol; Antigens, Differentiation, T-Lymphocyte; Carbam | 2019 |
Lamotrigine and Stevens-Johnson Syndrome Prevention.
Topics: Anticonvulsants; Carbamazepine; HLA-B Antigens; Humans; Lamotrigine; Stevens-Johnson Syndrome; Unite | 2021 |
Risks associated with lamotrigine prescription: a review and personal observations.
Topics: Antipsychotic Agents; Bipolar Disorder; Drug and Narcotic Control; Drug Prescriptions; Eosinophilia; | 2018 |
Lamotrigine-associated with toxic epidermal necrolysis: a case report and Chinese literature review.
Topics: Aged; Anticonvulsants; Asian People; Female; Humans; Lamotrigine; Stevens-Johnson Syndrome; Triazine | 2014 |
HLA-B*1502 increases the risk of phenytoin or lamotrigine induced Stevens-Johnson Syndrome/toxic epidermal necrolysis: evidence from a meta-analysis of nine case-control studies.
Topics: Anticonvulsants; Case-Control Studies; Epilepsy; Genetic Predisposition to Disease; HLA-B15 Antigen; | 2015 |
Association of HLA-B*1502 allele with lamotrigine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Han Chinese subjects: a meta-analysis.
Topics: Alleles; Anticonvulsants; Asian People; HLA-B15 Antigen; Humans; Lamotrigine; Stevens-Johnson Syndro | 2015 |
Lamotrigine-induced severe cutaneous adverse reaction: Update data from 1999-2014.
Topics: Adult; Aged; Anticonvulsants; Drug Therapy, Combination; Female; Humans; Lamotrigine; Male; Middle A | 2015 |
The role of lamotrigine in the treatment of short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing syndrome.
Topics: Anticonvulsants; Calcium Channel Blockers; Headache; Humans; Lamotrigine; Stevens-Johnson Syndrome; | 2011 |
Cyclosporine for SJS/TEN: a case series and review of the literature.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Infective Agents; Anticonvulsants; Cyclosporine | 2011 |
Rash in multicenter trials of lamotrigine in mood disorders: clinical relevance and management.
Topics: Anticonvulsants; Antimanic Agents; Bipolar Disorder; Cross-Sectional Studies; Depressive Disorder, M | 2002 |
Lamotrigine-induced toxic epidermal necrolysis treated with intravenous cyclosporin: a discussion of pathogenesis and immunosuppressive management.
Topics: Adult; Anticonvulsants; Cyclosporins; Epilepsy; Female; Humans; Immunosuppressive Agents; Injections | 1996 |
Lamotrigine-induced severe cutaneous adverse reactions.
Topics: Adolescent; Adult; Age Factors; Aged; Anticonvulsants; Child; Child, Preschool; Drug Therapy, Combin | 1998 |
Lamotrigine-associated rash: risk/benefit considerations in adults and children.
Topics: Adult; Age Factors; Anticonvulsants; Child; Drug Eruptions; Epilepsy; Humans; Incidence; Lamotrigine | 1999 |
1 trial available for lamotrigine and Stevens-Johnson Syndrome
| Article | Year |
|---|---|
Poor relevance of a lymphocyte proliferation assay in lamotrigine-induced Stevens-Johnson syndrome or toxic epidermal necrolysis.
Topics: Anticonvulsants; Apoptosis; Cell Proliferation; Cells, Cultured; Female; Humans; Lamotrigine; Male; | 2012 |
93 other studies available for lamotrigine and Stevens-Johnson Syndrome
| Article | Year |
|---|---|
Lamotrigine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Singapore: A case series.
Topics: Anticonvulsants; Humans; Lamotrigine; Singapore; Stevens-Johnson Syndrome | 2021 |
Association between human leukocyte antigens and cutaneous adverse drug reactions to antiepileptics and antibiotics in the Iranian population.
Topics: Adult; Anti-Bacterial Agents; Anticonvulsants; Carbamazepine; Case-Control Studies; Ciprofloxacin; F | 2022 |
New insight into the management of toxic epidermal necrolysis following the coadministration of lamotrigine and valproic acid.
Topics: Anticonvulsants; Humans; Lamotrigine; Stevens-Johnson Syndrome; Triazines; Valproic Acid | 2023 |
Association of Human Leukocyte Antigen Alleles with Carbamazepine- or Lamotrigine-Induced Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in an Iranian Population: A Case-control Study.
Topics: Alleles; Anticonvulsants; Asian People; Benzodiazepines; Carbamazepine; Case-Control Studies; HLA-B | 2023 |
Effects of dosage in new users of lamotrigine inducing epidermal necrolysis: Results of the German Registry of Severe Skin Reactions.
Topics: Adult; Anticonvulsants; Epilepsy; Female; Humans; Lamotrigine; Male; Registries; Stevens-Johnson Syn | 2023 |
Therapeutic Effects of Mesenchymal Stem Cells on a Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis Model.
Topics: Animals; Disease Models, Animal; Humans; Injections, Intravenous; Lamotrigine; Leukocytes, Mononucle | 2020 |
Antiepileptic combination therapy with Stevens-Johnson syndrome and toxic epidermal necrolysis: Analysis of a Japanese pharmacovigilance database.
Topics: Anticonvulsants; Carbamazepine; Clobazam; Clonazepam; Databases, Factual; Drug Therapy, Combination; | 2020 |
A Cautionary Tale of Etanercept Use in Patients With Toxic Epidermal Necrolysis.
Topics: Adult; Aged; Etanercept; Fatal Outcome; Female; Humans; Immunosuppressive Agents; Lamotrigine; Steve | 2021 |
Incidence rates of severe cutaneous adverse reactions due to antiseizure medication: A nationwide study using health claims data in Korea.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Child; Drug Hypersensiti | 2021 |
Does the dose of the culprit drug matter in hypersensitivity reactions?
Topics: Adrenal Cortex Hormones; Adult; Anticonvulsants; Female; Humans; Lamotrigine; Male; Skin; Stevens-Jo | 2020 |
Investigating the association of Lamotrigine and Phenytoin-induced Stevens-Johnson syndrome/Toxic Epidermal Necrolysis with HLA-B*1502 in Iranian population.
Topics: Adult; Alleles; Anticonvulsants; Case-Control Studies; Female; HLA-B15 Antigen; Humans; Iran; Lamotr | 2021 |
Risk of Stevens-Johnson syndrome and toxic epidermal necrolysis associated with anticonvulsants in a Japanese population: Matched case-control and cohort studies.
Topics: Adult; Anticonvulsants; Carbamazepine; Case-Control Studies; Clonazepam; Cohort Studies; Diazepam; F | 2021 |
Chronic ocular complications in lamotrigine vs. trimethoprim-sulfamethoxazole induced Stevens-Johnson syndrome/toxic epidermal necrolysis.
Topics: Cross-Sectional Studies; Humans; Lamotrigine; Retrospective Studies; Stevens-Johnson Syndrome; Trime | 2021 |
Toxic epidermal necrolysis and Stevens-Johnson syndrome/toxic epidermal necrolysis overlap in pediatric patients with a focus on newer antiepileptic drugs: A 25-year retrospective study at a single tertiary care center.
Topics: Adult; Anticonvulsants; Child; Humans; Lamotrigine; Retrospective Studies; Stevens-Johnson Syndrome; | 2021 |
Lamotrigine and its relationship with Stevens-Johnson syndrome and toxic epidermal necrolysis
Topics: Anticonvulsants; Humans; Lamotrigine; Skin; Stevens-Johnson Syndrome | 2020 |
Stevens - Johnson Syndrome Induced by Combination of Lamotrigine and Valproic Acid in a 9-Year-Old Boy.
Topics: Anticonvulsants; Child; Drug Therapy, Combination; Humans; Lamotrigine; Male; Stevens-Johnson Syndro | 2017 |
Adverse Cutaneous Drug Reactions Associated with Old- and New- Generation Antiepileptic Drugs Using the Japanese Pharmacovigilance Database.
Topics: Anticonvulsants; Databases, Factual; Drug-Related Side Effects and Adverse Reactions; Exanthema; Fem | 2019 |
Clinical features of and genetic predisposition to drug-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in a single Korean tertiary institution patients-investigating the relation between the HLA -B*4403 allele and lamotrigine.
Topics: Acetaminophen; Acetazolamide; Adult; Aged; Aged, 80 and over; Alleles; Allopurinol; Anti-Bacterial A | 2015 |
Bronchiolitis obliterans complicating a pneumothorax after Stevens-Johnson syndrome induced by lamotrigine.
Topics: Anticonvulsants; Bronchiolitis Obliterans; Child; Epilepsy; Female; Humans; Lamotrigine; Pneumothora | 2015 |
Stevens-Johnson syndrome: Old and new opportunities for prevention.
Topics: Adolescent; Anticonvulsants; Humans; Lamotrigine; Male; Skin; Stevens-Johnson Syndrome; Triazines | 2015 |
Liver dysfunction induced by systemic hypersensitivity reaction to lamotrigine: case report.
Topics: Adult; Alanine Transaminase; Anticonvulsants; Aspartate Aminotransferases; Drug Hypersensitivity; Hu | 2015 |
The use of plasmapheresis in a 4-year-old boy with toxic epidermal necrosis.
Topics: Anticonvulsants; Child, Preschool; Disease Progression; Drug Resistant Epilepsy; Humans; Lamotrigine | 2015 |
Spontaneous reporting of Stevens-Johnson syndrome and toxic epidermal necrolysis associated with antiepileptic drugs.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amines; Anticonvulsants; Carbamazepine; Child; Child, Pr | 2015 |
Development of an incipient Stevens-Johnson reaction while on a stable dose of lamotrigine.
Topics: Adult; Antidepressive Agents; Female; Humans; Lamotrigine; Quality Control; Stevens-Johnson Syndrome | 2016 |
HLA Allele Frequencies in 5802 Koreans: Varied Allele Types Associated with SJS/TEN According to Culprit Drugs.
Topics: Adult; Aged; Alleles; Allopurinol; Anticonvulsants; Asian People; Carbamazepine; Case-Control Studie | 2016 |
Incidence, causative factors and mortality rates of Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) in northern Italy: data from the REACT registry.
Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Allopurinol; Ch | 2016 |
Lamotrigine-induced toxic epidermal necrolysis treated with intravenous immunoglobulin and amniotic membranes.
Topics: Adult; Anticonvulsants; Biological Dressings; Bipolar Disorder; Female; Follow-Up Studies; Humans; I | 2008 |
Efficacy and safety of lamotrigine monotherapy in children and adolescents with epilepsy.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Electroencephalography; Epilepsies, Partial; E | 2009 |
Intravenous immunoglobulin in the treatment of lamotrigine- induced toxic epidermal necrolysis.
Topics: Blister; Child; Exanthema; Female; Fever; Humans; Immunoglobulins, Intravenous; Lamotrigine; Seizure | 2008 |
A case with Stevens Johnson syndrome triggered by combination of clobazam, lamotrigine, and valproic acid treatment.
Topics: Anticonvulsants; Benzodiazepines; Child, Preschool; Clobazam; Drug Therapy, Combination; Follow-Up S | 2009 |
Neopterin and C-reactive protein in the course of Stevens-Johnson syndrome: report of a case.
Topics: Anticonvulsants; Antidepressive Agents, Tricyclic; Biopsy; C-Reactive Protein; Depression; Drug Ther | 2009 |
High-resolution HLA genotyping and severe cutaneous adverse reactions in lamotrigine-treated patients.
Topics: Adolescent; Adult; Aged; Alleles; Analgesics; Anticonvulsants; Case-Control Studies; Child; Female; | 2009 |
Lamotrigine and bipolar disorder: new indication. Only after lithium, like other antiepileptics. Preventive effects in only one aspect of bipolar disorder, but with a risk of Lyell syndrome.
Topics: Anticonvulsants; Antimanic Agents; Bipolar Disorder; Depressive Disorder; Europe; Humans; Lamotrigin | 2009 |
Lamotrigine and absence seizures: new indication. Try valproic acid first.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Drug Approval; Epilepsy, Absence; Europe; Huma | 2009 |
Common risk allele in aromatic antiepileptic-drug induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Han Chinese.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alleles; Anticonvulsants; Asian People; Carbamazepine; C | 2010 |
Lyell syndrome and epileptic seizures after confusion between Lamictal and Lamisil.
Topics: Anticonvulsants; Antifungal Agents; Epilepsy; Humans; Lamotrigine; Medication Errors; Naphthalenes; | 2010 |
Association study of lamotrigine-induced cutaneous adverse reactions and HLA-B*1502 in a Han Chinese population.
Topics: Adolescent; Adult; Anticonvulsants; Asian People; Epilepsy; Female; Gene Frequency; Genotype; HLA-B | 2010 |
[Toxic epidermal necrolysis caused by erroneous substitution of lamotrigine for terbinafine].
Topics: Adolescent; Anticonvulsants; Female; Humans; Lamotrigine; Medication Errors; Stevens-Johnson Syndrom | 2010 |
Disseminated eruption of ectopic sebaceous glands following Stevens-Johnson syndrome.
Topics: Adolescent; Biopsy, Needle; Exanthema; Facial Dermatoses; Female; Follow-Up Studies; Humans; Immunoh | 2011 |
Severe cutaneous adverse reactions to antiepileptic drugs in Asians.
Topics: Adult; Anticonvulsants; Asian People; Carbamazepine; Exanthema; Female; Follow-Up Studies; Humans; L | 2011 |
[Lyell's disease--a case report].
Topics: Adolescent; Eye Diseases; Humans; Lamotrigine; Male; Stevens-Johnson Syndrome; Triazines | 2011 |
In a patient with toxic epidermal necrolysis, does intravenous immunoglobulin improve survival compared with supportive care?
Topics: Aged; Anticonvulsants; Biopsy; Epilepsy; Humans; Immunoglobulins, Intravenous; Immunologic Factors; | 2011 |
A lamotrigine induced toxic epidermal necrolysis in a child.
Topics: Anticonvulsants; Child; Drug Combinations; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Pir | 2013 |
Lamotrigine-induced toxic epidermal necrolysis in a young epileptic.
Topics: Anticonvulsants; Epilepsy; Female; Humans; Lamotrigine; Stevens-Johnson Syndrome; Triazines; Young A | 2011 |
HLA-B*1502 screening in carbamazepine and lamotrigine candidates of Asian background.
Topics: Antimanic Agents; Asian People; Carbamazepine; Genetic Predisposition to Disease; Genetic Testing; H | 2012 |
Acute skin failure.
Topics: Acute Disease; Amoxicillin; Anti-Bacterial Agents; Anticonvulsants; Biopsy; Diagnosis, Differential; | 2012 |
Toxic epidermal necrolysis with some features of acute generalized exanthematous pustulosis.
Topics: Acute Generalized Exanthematous Pustulosis; Administration, Oral; Adult; Anticonvulsants; Biopsy; Dr | 2013 |
Use of carbamazepine and lamotrigine in a Taiwanese diabetic patient with bipolar disorder.
Topics: Antimanic Agents; Bipolar Disorder; Carbamazepine; Diabetes Complications; Drug Therapy, Combination | 2012 |
Lamotrigine and rash: scratching beneath the surface.
Topics: Adult; Adverse Drug Reaction Reporting Systems; Anticonvulsants; Antimanic Agents; Bipolar Disorder; | 2002 |
Management of toxic epidermal necrolysis in a 15-year-old girl.
Topics: Adolescent; Anticonvulsants; Body Surface Area; Burn Units; Critical Care; Diagnosis, Differential; | 2003 |
[Toxic epidermal necrolysis due to lamotrigine].
Topics: Anticonvulsants; Child; Epilepsy; Fatal Outcome; Female; Humans; Lamotrigine; Stevens-Johnson Syndro | 2003 |
Improvement of toxic epidermal necrolysis after the early administration of a single high dose of intravenous immunoglobulin.
Topics: Anticonvulsants; Antigens, CD; Blister; Child, Preschool; Cytokines; Cytotoxicity Tests, Immunologic | 2003 |
Suspected lamotrigine-induced toxic epidermal necrolysis.
Topics: Adult; Anticonvulsants; Drug Therapy, Combination; Female; Humans; Lamotrigine; Myoclonic Epilepsy, | 2003 |
Visual loss in a patient with lamotrigine-induced cicatrizing conjunctivitis.
Topics: Adult; Anticonvulsants; Cicatrix; Conjunctivitis, Allergic; Epilepsy, Absence; Female; Humans; Lamot | 2003 |
Lamotrigine and informed consent.
Topics: Antimanic Agents; Child; Clinical Trials as Topic; Depressive Disorder, Major; Humans; Informed Cons | 2004 |
Early cyclosporine treatment of incipient toxic epidermal necrolysis induced by concomitant use of lamotrigine and sodium valproate.
Topics: Adult; Anticonvulsants; Cyclosporine; Dermatologic Agents; Drug Therapy, Combination; Epilepsy, Comp | 2004 |
Free autologous buccal mucosal graft transplantation to treat ocular complications after toxic epidermal necrolysis: case report.
Topics: Adult; Anticonvulsants; Cheek; Contact Lenses; Corneal Neovascularization; Corneal Opacity; Dry Eye | 2004 |
Toxic epidermal caused by lamotrigine.
Topics: Adult; Anticonvulsants; Female; Humans; Lamotrigine; Middle Aged; Stevens-Johnson Syndrome; Triazine | 2004 |
Stevens-Johnson syndrome associated with single high dose of lamotrigine in a patient taking valproate.
Topics: Adult; Anticonvulsants; Drug Interactions; Epilepsy, Tonic-Clonic; Humans; Lamotrigine; Male; Steven | 2005 |
Risk of Stevens-Johnson syndrome and toxic epidermal necrolysis in new users of antiepileptics.
Topics: Anticonvulsants; Carbamazepine; Causality; Epilepsy; Germany; Humans; Incidence; Inpatients; Lamotri | 2005 |
Images in clinical medicine. Stevens-Johnson syndrome.
Topics: Adult; Anticonvulsants; Drug Synergism; Female; Humans; Lamotrigine; Stevens-Johnson Syndrome; Triaz | 2005 |
Toxic epidermal necrolysis associated with concomitant use of lamotrigine and carbamazepine: a case report.
Topics: Adult; Carbamazepine; Combined Modality Therapy; Drug Interactions; Drug Therapy, Combination; Femal | 2005 |
Toxic epidermal necrolysis with combination lamotrigine and valproate in bipolar disorder.
Topics: Adult; Anticonvulsants; Bipolar Disorder; Drug Therapy, Combination; Female; Humans; Lamotrigine; St | 2006 |
[Toxic epidermal necrolysis caused by lamotrigine].
Topics: Adult; Anticonvulsants; Female; Humans; Lamotrigine; Stevens-Johnson Syndrome; Triazines | 2005 |
Lamotrigine-induced toxic epidermal necrolysis in three patients treated for bipolar disorder.
Topics: Adolescent; Adult; Anticonvulsants; Bipolar Disorder; Burn Units; Female; Humans; Lamotrigine; Skin; | 2006 |
Drug Rash with eosinophilia and systemic symptoms versus Stevens-Johnson Syndrome--a case that indicates a stumbling block in the current classification.
Topics: Adult; Diagnosis, Differential; Drug Eruptions; Eosinophilia; Humans; Lamotrigine; Male; Stevens-Joh | 2006 |
Lamotrigine-induced Stevens-Johnson syndrome.
Topics: Adult; Anticonvulsants; Female; Humans; Lamotrigine; New York City; Stevens-Johnson Syndrome; Triazi | 2007 |
Lyell's syndrome skin lesions treated by Veloderm.
Topics: Adult; Humans; Lamotrigine; Male; Occlusive Dressings; Polysaccharides; Stevens-Johnson Syndrome; Tr | 2007 |
Stevens-Johnson syndrome due to concomitant use of lamotrigine and valproic acid.
Topics: Adult; Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Epilepsy; Female; Humans; Lamotrig | 2007 |
Lamotrigine-associated Stevens-Johnson syndrome after discontinuation of interferon, ribavirin, and filgrastim: a case report.
Topics: Adult; Antimanic Agents; Bipolar Disorder; Calcium Channel Blockers; Filgrastim; Granulocyte Colony- | 2007 |
Association between HLA-B*1502 allele and antiepileptic drug-induced cutaneous reactions in Han Chinese.
Topics: Adolescent; Adult; Alleles; Anticonvulsants; Asian People; Carbamazepine; Case-Control Studies; Chil | 2007 |
Association between HLA-B*1502 allele and antiepileptic drug-induced cutaneous reactions in Han Chinese.
Topics: Adolescent; Adult; Alleles; Anticonvulsants; Asian People; Carbamazepine; Case-Control Studies; Chil | 2007 |
Association between HLA-B*1502 allele and antiepileptic drug-induced cutaneous reactions in Han Chinese.
Topics: Adolescent; Adult; Alleles; Anticonvulsants; Asian People; Carbamazepine; Case-Control Studies; Chil | 2007 |
Association between HLA-B*1502 allele and antiepileptic drug-induced cutaneous reactions in Han Chinese.
Topics: Adolescent; Adult; Alleles; Anticonvulsants; Asian People; Carbamazepine; Case-Control Studies; Chil | 2007 |
Concomitant use of lamotrigine and aripiprazole increases risk of Stevens-Johnson syndrome?
Topics: Adult; Antimanic Agents; Antipsychotic Agents; Aripiprazole; Drug Therapy, Combination; Female; Huma | 2007 |
Stevens-Johnson syndrome and toxic epidermal necrolysis: assessment of medication risks with emphasis on recently marketed drugs. The EuroSCAR-study.
Topics: Adrenal Cortex Hormones; Adult; Aged; Analgesics; Case-Control Studies; Humans; Lamotrigine; Middle | 2008 |
Lamotrigine versus carbamazepine in epilepsy.
Topics: Adult; Anticonvulsants; Clonazepam; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Humans; Lamotrigi | 1995 |
Fatal course of toxic epidermal necrolysis under treatment with lamotrigine.
Topics: Anticonvulsants; Carbamazepine; Drug Interactions; Fatal Outcome; Humans; Lamotrigine; Male; Middle | 1995 |
Lamotrigine and toxic epidermal necrolysis.
Topics: Adult; Anticonvulsants; Dermatitis, Phototoxic; Epilepsy; Female; Humans; Lamotrigine; Male; Stevens | 1996 |
Lamotrigine and toxic epidermal necrolysis.
Topics: Adult; Anticonvulsants; Humans; Lamotrigine; Lymphocyte Activation; Male; Stevens-Johnson Syndrome; | 1996 |
Toxic epidermal necrolysis after treatment with lamotrigine (Lamictal).
Topics: Adult; Anticonvulsants; Biopsy; Dose-Response Relationship, Drug; Electroencephalography; Epilepsies | 1997 |
Glaxo Wellcome epilepsy drug exhibits fatal side effects.
Topics: Adult; Anticonvulsants; Child; Death; Drug Eruptions; Drug Industry; Epilepsy; Humans; Lamotrigine; | 1997 |
Suspected lamotrigine-induced toxic epidermal necrolysis.
Topics: Aged; Anticonvulsants; Humans; Lamotrigine; Male; Seizures; Stevens-Johnson Syndrome; Triazines | 1997 |
Lamotrigine-induced Stevens-Johnson syndrome: demonstration of specific lymphocyte reactivity in vitro.
Topics: Adult; Anticonvulsants; Concanavalin A; Drug Eruptions; Drug Therapy, Combination; Half-Life; Humans | 1997 |
Lamotrigine and toxic epidermal necrolysis.
Topics: Anticonvulsants; Drug Therapy, Combination; Humans; Infant; Lamotrigine; Male; Stevens-Johnson Syndr | 1997 |
Safety of long-term lamotrigine in epilepsy.
Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Age Factors; Aged; Anticonvulsants; Chil | 1997 |
[Toxic epidermal necrolysis after treatment with lamotrigine].
Topics: Adult; Anticonvulsants; Epilepsy; Humans; Lamotrigine; Male; Stevens-Johnson Syndrome; Triazines | 1998 |
[Antiepileptic treatment with lamotrigine].
Topics: Anticonvulsants; Contraindications; Epilepsy; Humans; Lamotrigine; Stevens-Johnson Syndrome; Triazin | 1999 |
[Lyell syndrome and Stevens-Johnson syndrome caused by lamotrigine].
Topics: Adolescent; Anticonvulsants; Child; Dose-Response Relationship, Drug; Drug Hypersensitivity; Drug Th | 1999 |
Photo Quiz.
Topics: Aged; Anticonvulsants; Drug Interactions; Epilepsy; Female; Humans; Lamotrigine; Skin; Stevens-Johns | 1999 |
Stevens-Johnson syndrome and antiepileptics.
Topics: Adult; Anticonvulsants; Child; Drug Therapy, Combination; Epilepsy; Humans; Lamotrigine; Stevens-Joh | 1999 |
Prolonged toxic epidermal necrolysis due to Lamotrigine.
Topics: Adult; Anticonvulsants; Drug Interactions; Humans; Lamotrigine; Male; Seizures; Stevens-Johnson Synd | 2000 |
Stevens-Johnson syndrome associated with concomitant use of lamotrigine and valproic acid.
Topics: Adult; Anticonvulsants; Antimanic Agents; Drug Therapy, Combination; Female; Humans; Lamotrigine; Ps | 2000 |
Valproate and other anticonvulsants for psychiatric disorders.
Topics: Abnormalities, Drug-Induced; Acetates; Adult; Amines; Anti-Anxiety Agents; Anticonvulsants; Bipolar | 2000 |
[Overlapping acute disseminated exanthematous pustulosis and toxic epidermal necrolysis].
Topics: Acute Disease; Adult; Anticonvulsants; Diagnosis, Differential; Exanthema; Female; Fever; Humans; La | 2001 |
[Toxic epidermal necrolysis treated with intravenous immunoglobulin].
Topics: Anticonvulsants; Child; Epilepsy; Female; Follow-Up Studies; Humans; Immunoglobulins, Intravenous; L | 2002 |