lamotrigine has been researched along with Status Epilepticus in 24 studies
Status Epilepticus: A prolonged seizure or seizures repeated frequently enough to prevent recovery between episodes occurring over a period of 20-30 minutes. The most common subtype is generalized tonic-clonic status epilepticus, a potentially fatal condition associated with neuronal injury and respiratory and metabolic dysfunction. Nonconvulsive forms include petit mal status and complex partial status, which may manifest as behavioral disturbances. Simple partial status epilepticus consists of persistent motor, sensory, or autonomic seizures that do not impair cognition (see also EPILEPSIA PARTIALIS CONTINUA). Subclinical status epilepticus generally refers to seizures occurring in an unresponsive or comatose individual in the absence of overt signs of seizure activity. (From N Engl J Med 1998 Apr 2;338(14):970-6; Neurologia 1997 Dec;12 Suppl 6:25-30)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The anticonvulsant and antioxidant effects of lamotrigine on status epilepticus (SE) are incompletely understood." | 8.31 | Anticonvulsant and antioxidant effects of lamotrigine on pilocarpine-induced status epilepticus in mice. ( Fujiki, M; Kamida, T; Momii, Y; Onishi, K; Sugita, K, 2023) |
| "To describe lamotrigine intoxication paradoxically producing status epilepticus in an adult with localization-related epilepsy." | 7.74 | Lamotrigine intoxication provoking status epilepticus in an adult with localization-related epilepsy. ( Dinnerstein, E; Jobst, BC; Williamson, PD, 2007) |
| "We report on the aggravation of absence seizures by lamotrigine leading to absence status epilepticus in a child." | 7.73 | Recurrent absence status epilepticus (spike-and-wave stupor) associated with lamotrigine therapy. ( Hasan, M; Lerman-Sagie, T; Lev, D; Watemberg, N, 2006) |
| "An 8-year-old girl with Lennox-Gastaut syndrome showed a partial reduction in seizure frequency when lamotrigine (LTG), 15 mg/kg per day, was added to clobazam (CLB) and vigabatrin (VGB)." | 7.70 | Myoclonic status epilepticus following high-dosage lamotrigine therapy. ( Belmonte, A; Guerrini, R; Parmeggiani, L; Perucca, E, 1999) |
| " Therefore, in the present study, the neuroprotective effects and mechanisms of vit-D alone or in combination with lamotrigine have been evaluated in the lithium-pilocarpine model of SE in rats." | 5.46 | Neuroprotective effects of vitamin D alone or in combination with lamotrigine against lithium-pilocarpine model of status epilepticus in rats. ( Abdel-Wahab, AF; Afify, MA; Al Ghamdi, SS; Bamagous, GA; ElSawy, NA; Ibrahim, IAA; Mahfoz, AM; Shahzad, N, 2017) |
| "A 16-year-old woman with MELAS developed fever and myoclonic epilepsy which improved with conventional anti-epileptic drugs." | 5.39 | [A case of mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) with treatment-resistant status epilepticus that was effectively treated with lamotrigine]. ( Hayashi, S; Kai, T; Maruyama, Y; Masuda, S; Nagado, T; Tokunaga, H, 2013) |
| "Status epilepticus was induced by electric stimulation of the perforant pathway (PP) in rats." | 5.31 | Effect of lamotrigine treatment on status epilepticus-induced neuronal damage and memory impairment in rat. ( Halonen, T; Nissinen, J; Pitkänen, A, 2001) |
| "Status epilepticus was induced in rats with actively epileptogenic cortical cobalt lesions by administration of homocysteine thiolactone." | 5.29 | Lamotrigine vs. phenytoin for treatment of status epilepticus: comparison in an experimental model. ( Hyun, B; Jaing, Q; Treiman, DM; Walton, NY, 1996) |
| "The anticonvulsant and antioxidant effects of lamotrigine on status epilepticus (SE) are incompletely understood." | 4.31 | Anticonvulsant and antioxidant effects of lamotrigine on pilocarpine-induced status epilepticus in mice. ( Fujiki, M; Kamida, T; Momii, Y; Onishi, K; Sugita, K, 2023) |
| "To describe lamotrigine intoxication paradoxically producing status epilepticus in an adult with localization-related epilepsy." | 3.74 | Lamotrigine intoxication provoking status epilepticus in an adult with localization-related epilepsy. ( Dinnerstein, E; Jobst, BC; Williamson, PD, 2007) |
| "We report on the aggravation of absence seizures by lamotrigine leading to absence status epilepticus in a child." | 3.73 | Recurrent absence status epilepticus (spike-and-wave stupor) associated with lamotrigine therapy. ( Hasan, M; Lerman-Sagie, T; Lev, D; Watemberg, N, 2006) |
| "Reversible neurotoxic symptoms were observed in three adult patients with absence status epilepticus on lamotrigine (LTG) therapy after administration of an IV bolus followed by oral valproic acid (VPA)." | 3.72 | Neurotoxicity following addition of intravenous valproate to lamotrigine therapy. ( Burneo, JG; Faught, E; Knowlton, RC; Kuzniecky, RI; Lawn, N; Limdi, N; Mendez, M; Prasad, A; Welty, TE, 2003) |
| "An 8-year-old girl with Lennox-Gastaut syndrome showed a partial reduction in seizure frequency when lamotrigine (LTG), 15 mg/kg per day, was added to clobazam (CLB) and vigabatrin (VGB)." | 3.70 | Myoclonic status epilepticus following high-dosage lamotrigine therapy. ( Belmonte, A; Guerrini, R; Parmeggiani, L; Perucca, E, 1999) |
| "Then, spontaneous recurrent seizures (SRS), neuronal loss and astrogliosis were assessed." | 1.51 | The effects of lamotrigine and ethosuximide on seizure frequency, neuronal loss, and astrogliosis in a model of temporal-lobe epilepsy. ( Chen, Y; Sun, M; van Luijtelaar, G; Wang, J; Wang, Q, 2019) |
| " Therefore, in the present study, the neuroprotective effects and mechanisms of vit-D alone or in combination with lamotrigine have been evaluated in the lithium-pilocarpine model of SE in rats." | 1.46 | Neuroprotective effects of vitamin D alone or in combination with lamotrigine against lithium-pilocarpine model of status epilepticus in rats. ( Abdel-Wahab, AF; Afify, MA; Al Ghamdi, SS; Bamagous, GA; ElSawy, NA; Ibrahim, IAA; Mahfoz, AM; Shahzad, N, 2017) |
| "A 16-year-old woman with MELAS developed fever and myoclonic epilepsy which improved with conventional anti-epileptic drugs." | 1.39 | [A case of mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) with treatment-resistant status epilepticus that was effectively treated with lamotrigine]. ( Hayashi, S; Kai, T; Maruyama, Y; Masuda, S; Nagado, T; Tokunaga, H, 2013) |
| "We report a case of cardiac arrest and status epilepticus following a massive LTG overdose." | 1.37 | Severe sodium channel blockade and cardiovascular collapse due to a massive lamotrigine overdose. ( Ly, BT; Minns, AB; Nogar, JN; Savaser, DJ, 2011) |
| "Absence status was aggravated with carbamazepine and generalised tonic-clonic seizures were not controlled with ethosuximide." | 1.36 | Unilateral continuous subclinical paroxysmal activity: an unusual finding in a patient with recurrent absence status. ( Genton, P; Velizarova, R, 2010) |
| " The number or dosage of AEDs were more often increased in pregnancies with seizures (OR: 3." | 1.33 | Seizure control and treatment in pregnancy: observations from the EURAP epilepsy pregnancy registry. ( , 2006) |
| "Status epilepticus was induced by electric stimulation of the perforant pathway (PP) in rats." | 1.31 | Effect of lamotrigine treatment on status epilepticus-induced neuronal damage and memory impairment in rat. ( Halonen, T; Nissinen, J; Pitkänen, A, 2001) |
| "Status epilepticus was induced in rats with actively epileptogenic cortical cobalt lesions by administration of homocysteine thiolactone." | 1.29 | Lamotrigine vs. phenytoin for treatment of status epilepticus: comparison in an experimental model. ( Hyun, B; Jaing, Q; Treiman, DM; Walton, NY, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (25.00) | 18.2507 |
| 2000's | 9 (37.50) | 29.6817 |
| 2010's | 8 (33.33) | 24.3611 |
| 2020's | 1 (4.17) | 2.80 |
| Authors | Studies |
|---|---|
| Onishi, K | 2 |
| Kamida, T | 2 |
| Fujiki, M | 2 |
| Momii, Y | 2 |
| Sugita, K | 2 |
| Mahfoz, AM | 1 |
| Abdel-Wahab, AF | 1 |
| Afify, MA | 1 |
| Shahzad, N | 1 |
| Ibrahim, IAA | 1 |
| ElSawy, NA | 1 |
| Bamagous, GA | 1 |
| Al Ghamdi, SS | 1 |
| Shimogori, K | 1 |
| Doden, T | 1 |
| Oguchi, K | 1 |
| Hashimoto, T | 1 |
| Wang, J | 1 |
| Chen, Y | 1 |
| Wang, Q | 1 |
| van Luijtelaar, G | 1 |
| Sun, M | 1 |
| Kai, T | 1 |
| Masuda, S | 1 |
| Tokunaga, H | 1 |
| Hayashi, S | 1 |
| Nagado, T | 1 |
| Maruyama, Y | 1 |
| Grosso, S | 1 |
| Ferranti, S | 1 |
| Gaggiano, C | 1 |
| Grande, E | 1 |
| Loi, B | 1 |
| Di Bartolo, R | 1 |
| Konieczny, PL | 1 |
| Reimer, R | 1 |
| Velizarova, R | 1 |
| Genton, P | 1 |
| Nogar, JN | 1 |
| Minns, AB | 1 |
| Savaser, DJ | 1 |
| Ly, BT | 1 |
| Deng, Y | 1 |
| Wang, M | 1 |
| Wang, W | 1 |
| Ma, C | 1 |
| He, N | 1 |
| Trinka, E | 1 |
| Dilitz, E | 1 |
| Unterberger, I | 1 |
| Luef, G | 1 |
| Deisenhammer, F | 1 |
| Niedermüller, U | 1 |
| Thaler, C | 1 |
| Bauer, G | 1 |
| Burneo, JG | 1 |
| Limdi, N | 1 |
| Kuzniecky, RI | 1 |
| Knowlton, RC | 1 |
| Mendez, M | 1 |
| Lawn, N | 1 |
| Faught, E | 1 |
| Welty, TE | 1 |
| Prasad, A | 1 |
| Penovich, P | 2 |
| Gaily, E | 1 |
| Hasan, M | 1 |
| Lerman-Sagie, T | 1 |
| Lev, D | 1 |
| Watemberg, N | 1 |
| Dinnerstein, E | 1 |
| Jobst, BC | 1 |
| Williamson, PD | 1 |
| Delima, SI | 1 |
| Walsh, LE | 1 |
| Golomb, MR | 1 |
| Nadarajah, J | 1 |
| Duggan, L | 1 |
| Walton, NY | 1 |
| Jaing, Q | 1 |
| Hyun, B | 1 |
| Treiman, DM | 1 |
| Mims, J | 1 |
| Ritter, F | 1 |
| Frost, MD | 1 |
| Bauer, J | 1 |
| Helmstaedter, C | 1 |
| Elger, CE | 1 |
| Guerrini, R | 1 |
| Belmonte, A | 1 |
| Parmeggiani, L | 1 |
| Perucca, E | 1 |
| Halonen, T | 1 |
| Nissinen, J | 1 |
| Pitkänen, A | 1 |
| Pisani, F | 1 |
| Gallitto, G | 1 |
| Di Perri, R | 1 |
24 other studies available for lamotrigine and Status Epilepticus
| Article | Year |
|---|---|
Anticonvulsant and antioxidant effects of lamotrigine on pilocarpine-induced status epilepticus in mice.
Topics: Animals; Anticonvulsants; Antioxidants; Dizocilpine Maleate; Glutathione; Hippocampus; Lamotrigine; | 2023 |
Anticonvulsant and antioxidant effects of lamotrigine on pilocarpine-induced status epilepticus in mice.
Topics: Animals; Anticonvulsants; Antioxidants; Dizocilpine Maleate; Glutathione; Hippocampus; Lamotrigine; | 2023 |
Anticonvulsant and antioxidant effects of lamotrigine on pilocarpine-induced status epilepticus in mice.
Topics: Animals; Anticonvulsants; Antioxidants; Dizocilpine Maleate; Glutathione; Hippocampus; Lamotrigine; | 2023 |
Anticonvulsant and antioxidant effects of lamotrigine on pilocarpine-induced status epilepticus in mice.
Topics: Animals; Anticonvulsants; Antioxidants; Dizocilpine Maleate; Glutathione; Hippocampus; Lamotrigine; | 2023 |
Neuroprotective effects of vitamin D alone or in combination with lamotrigine against lithium-pilocarpine model of status epilepticus in rats.
Topics: Animals; Anticonvulsants; Antioxidants; Disease Models, Animal; Drug Therapy, Combination; Lamotrigi | 2017 |
Thalamic and cerebellar hypermetabolism and cortical hypometabolism during absence status epilepticus.
Topics: Adolescent; Anticonvulsants; Cerebral Cortex; Clonazepam; Delta Rhythm; Electroencephalography; Fema | 2017 |
The effects of lamotrigine and ethosuximide on seizure frequency, neuronal loss, and astrogliosis in a model of temporal-lobe epilepsy.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Electroencephalography; Epilepsy, Temporal Lobe; E | 2019 |
[A case of mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) with treatment-resistant status epilepticus that was effectively treated with lamotrigine].
Topics: Adolescent; Anticonvulsants; Drug Resistance; Female; Humans; Lamotrigine; MELAS Syndrome; Status Ep | 2013 |
Massive lamotrigine poisoning. A case report.
Topics: Anticonvulsants; Child, Preschool; Diagnosis, Differential; Drug Overdose; Dyskinesia, Drug-Induced; | 2017 |
25-year-old woman with new-onset seizures.
Topics: Adult; Anticonvulsants; Carcinoma, Basal Cell; Female; Humans; Lamotrigine; Leukemia, Myeloid, Acute | 2009 |
Unilateral continuous subclinical paroxysmal activity: an unusual finding in a patient with recurrent absence status.
Topics: Adult; Anticonvulsants; Brain; Carbamazepine; Diagnosis, Differential; Dose-Response Relationship, D | 2010 |
Severe sodium channel blockade and cardiovascular collapse due to a massive lamotrigine overdose.
Topics: Calcium Channel Blockers; Drug Overdose; Female; Heart Arrest; Humans; Lamotrigine; Middle Aged; Sta | 2011 |
Comparison and effects of acute lamotrigine treatment on extracellular excitatory amino acids in the hippocampus of PTZ-kindled epileptic and PTZ-induced status epilepticus rats.
Topics: Animals; Aspartic Acid; Epilepsy; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Kin | 2013 |
Non convulsive status epilepticus after replacement of valproate with lamotrigine.
Topics: Adult; Aged; Anticoagulants; Benzodiazepines; Electroencephalography; Epilepsy, Generalized; Female; | 2002 |
Neurotoxicity following addition of intravenous valproate to lamotrigine therapy.
Topics: Administration, Oral; Adult; Ammonia; Anticonvulsants; Confusion; Drug Interactions; Drug Therapy, C | 2003 |
What can we say to women of reproductive age with epilepsy?
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anticonvulsants; Dose-Response Relationship, Drug; E | 2005 |
Seizure control and treatment in pregnancy: observations from the EURAP epilepsy pregnancy registry.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Femal | 2006 |
Recurrent absence status epilepticus (spike-and-wave stupor) associated with lamotrigine therapy.
Topics: Anticonvulsants; Child; Dose-Response Relationship, Drug; Drug Administration Schedule; Epilepsy, Ab | 2006 |
Lamotrigine intoxication provoking status epilepticus in an adult with localization-related epilepsy.
Topics: Adult; Anticonvulsants; Electroencephalography; Epilepsy, Generalized; Female; Humans; Lamotrigine; | 2007 |
Simultaneous toxicities in a child on multiple anticonvulsants.
Topics: Anticonvulsants; Bone Marrow; Bone Marrow Diseases; Chemical and Drug Induced Liver Injury; Child, P | 2008 |
A missed diagnosis. A missed opportunity for community integration.
Topics: Adult; Anticonvulsants; Combined Modality Therapy; Diagnosis, Differential; Electroencephalography; | 1995 |
Lamotrigine vs. phenytoin for treatment of status epilepticus: comparison in an experimental model.
Topics: Animals; Anticonvulsants; Brain; Chromatography, High Pressure Liquid; Cobalt; Convulsants; Electrod | 1996 |
Treatment with high doses of lamotrigine in children and adolescents with refractory seizures.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Eruptio | 1997 |
Nonconvulsive status epilepticus with generalized 'fast activity'.
Topics: Alpha Rhythm; Anticonvulsants; Cerebral Cortex; Diagnosis, Differential; Drug Therapy, Combination; | 1997 |
Myoclonic status epilepticus following high-dosage lamotrigine therapy.
Topics: Anticonvulsants; Child; Electroencephalography; Epilepsies, Myoclonic; Epilepsy, Absence; Female; Hu | 1999 |
Effect of lamotrigine treatment on status epilepticus-induced neuronal damage and memory impairment in rat.
Topics: Animals; Anticonvulsants; Body Temperature; Body Weight; Brain; Lamotrigine; Male; Memory Disorders; | 2001 |
Could lamotrigine be useful in status epilepticus? A case report.
Topics: Adolescent; Anticonvulsants; Dose-Response Relationship, Drug; Electroencephalography; Female; Human | 1991 |