Page last updated: 2024-10-30

lamotrigine and Spinal Cord Injuries

lamotrigine has been researched along with Spinal Cord Injuries in 3 studies

Spinal Cord Injuries: Penetrating and non-penetrating injuries to the spinal cord resulting from traumatic external forces (e.g., WOUNDS, GUNSHOT; WHIPLASH INJURIES; etc.).

Research Excerpts

ExcerptRelevanceReference
"Amitriptyline was administered orally at doses of 25, 50 and 100 mg once daily at night time, and lamotrigine was administered orally at doses of 25, 50 and 100 mg twice daily, both for 1 week by means of optional titration."2.84Effectiveness of amitriptyline and lamotrigine in traumatic spinal cord injury-induced neuropathic pain: a randomized longitudinal comparative study. ( Agarwal, N; Joshi, M, 2017)
"Lamotrigine was generally well tolerated."2.70Lamotrigine in spinal cord injury pain: a randomized controlled trial. ( Bach, FW; Finnerup, NB; Jensen, TS; Johannesen, IL; Sindrup, SH, 2002)
"Lamotrigine is an antiepileptic drug that inhibits presynaptic voltage-gated sodium channels and reduces the presynaptic release of glutamate in pathological states."1.35Ultrastructure protection and attenuation of lipid peroxidation after blockade of presynaptic release of glutamate by lamotrigine in experimental spinal cord injury. ( Dursun, A; Ofluoglu, E; Ozogul, C; Oztanir, N; Pasaoglu, A; Pasaoglu, H; Tufan, K; Uzum, N, 2008)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Agarwal, N1
Joshi, M1
Tufan, K1
Oztanir, N1
Ofluoglu, E1
Ozogul, C1
Uzum, N1
Dursun, A1
Pasaoglu, H1
Pasaoglu, A1
Finnerup, NB1
Sindrup, SH1
Bach, FW1
Johannesen, IL1
Jensen, TS1

Trials

2 trials available for lamotrigine and Spinal Cord Injuries

ArticleYear
Effectiveness of amitriptyline and lamotrigine in traumatic spinal cord injury-induced neuropathic pain: a randomized longitudinal comparative study.
    Spinal cord, 2017, Volume: 55, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Amitriptyline; Anticonvulsants; Antidepressive Agents, Tric

2017
Lamotrigine in spinal cord injury pain: a randomized controlled trial.
    Pain, 2002, Volume: 96, Issue:3

    Topics: Adult; Analgesics; Cross-Over Studies; Double-Blind Method; Female; Humans; Lamotrigine; Male; Middl

2002

Other Studies

1 other study available for lamotrigine and Spinal Cord Injuries

ArticleYear
Ultrastructure protection and attenuation of lipid peroxidation after blockade of presynaptic release of glutamate by lamotrigine in experimental spinal cord injury.
    Neurosurgical focus, 2008, Volume: 25, Issue:5

    Topics: Animals; Calcium Channel Blockers; Disease Models, Animal; Female; Glutamic Acid; Glutathione Peroxi

2008