Page last updated: 2024-10-30

lamotrigine and Sleep Initiation and Maintenance Disorders

lamotrigine has been researched along with Sleep Initiation and Maintenance Disorders in 6 studies

Sleep Initiation and Maintenance Disorders: Disorders characterized by impairment of the ability to initiate or maintain sleep. This may occur as a primary disorder or in association with another medical or psychiatric condition.

Research Excerpts

ExcerptRelevanceReference
"To correlate lamotrigine (LTG) serum concentrations (levels) with tolerability in patients with epilepsy."8.82Correlating lamotrigine serum concentrations with tolerability in patients with epilepsy. ( Adams, DJ; Bazil, CW; Buchsbaum, R; Du, Y; Hager, M; Hirsch, LJ; Morrell, MJ; Resor, SR; Spencer, HT; Straka, T; Weintraub, D, 2004)
"No subjects reported insomnia with treatment."5.31The effects of lamotrigine on sleep in patients with epilepsy. ( Dinner, D; Foldvary, N; Lee, J; Morris, HH; Perry, M, 2001)
"To correlate lamotrigine (LTG) serum concentrations (levels) with tolerability in patients with epilepsy."4.82Correlating lamotrigine serum concentrations with tolerability in patients with epilepsy. ( Adams, DJ; Bazil, CW; Buchsbaum, R; Du, Y; Hager, M; Hirsch, LJ; Morrell, MJ; Resor, SR; Spencer, HT; Straka, T; Weintraub, D, 2004)
"To review the incidence of lamotrigine (LTG)-associated insomnia in an adult tertiary care epilepsy outpatient clinic."3.70Lamotrigine associated with insomnia. ( Sadler, M, 1999)
" Blood samples were collected on Days -1 and 14 for determination of lamotrigine steady-state pharmacokinetic parameters."2.74A non-randomized study to investigate the effects of the atypical antipsychotic aripiprazole on the steady-state pharmacokinetics of lamotrigine in patients with bipolar I disorder. ( Balch, AH; Benson, J; Boulton, DW; Carlson, BX; Croop, R; Mallikaarjun, S; Schieber, FC, 2009)
" The adverse effect (AE) profile of this combination needs clarification."2.69Adding lamotrigine to valproate: incidence of rash and other adverse effects. Postmarketing Antiepileptic Drug Survey (PADS) Group. ( Faught, E; French, J; Harden, C; Jacobson, M; Montouris, G; Morris, G; Rosenfeld, W, 1999)
"No subjects reported insomnia with treatment."1.31The effects of lamotrigine on sleep in patients with epilepsy. ( Dinner, D; Foldvary, N; Lee, J; Morris, HH; Perry, M, 2001)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's4 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schieber, FC1
Boulton, DW1
Balch, AH1
Croop, R1
Mallikaarjun, S1
Benson, J1
Carlson, BX1
Hirsch, LJ1
Weintraub, D1
Du, Y1
Buchsbaum, R1
Spencer, HT1
Hager, M1
Straka, T1
Bazil, CW1
Adams, DJ1
Resor, SR1
Morrell, MJ1
Sadler, M1
Faught, E1
Morris, G1
Jacobson, M1
French, J1
Harden, C1
Montouris, G1
Rosenfeld, W1
Nagarajan, L1
Foldvary, N1
Perry, M1
Lee, J1
Dinner, D1
Morris, HH1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Pilot Study of Prophylactic Management of Lamotrigine for Bipolar Disorder in Pregnant Women[NCT03774641]20 participants (Anticipated)Observational2018-12-03Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for lamotrigine and Sleep Initiation and Maintenance Disorders

ArticleYear
Correlating lamotrigine serum concentrations with tolerability in patients with epilepsy.
    Neurology, 2004, Sep-28, Volume: 63, Issue:6

    Topics: Anticonvulsants; Dose-Response Relationship, Drug; Drug Eruptions; Drug Interactions; Drug Therapy,

2004

Trials

2 trials available for lamotrigine and Sleep Initiation and Maintenance Disorders

ArticleYear
A non-randomized study to investigate the effects of the atypical antipsychotic aripiprazole on the steady-state pharmacokinetics of lamotrigine in patients with bipolar I disorder.
    Human psychopharmacology, 2009, Volume: 24, Issue:2

    Topics: Adult; Anticonvulsants; Antipsychotic Agents; Area Under Curve; Aripiprazole; Bipolar Disorder; Dose

2009
Adding lamotrigine to valproate: incidence of rash and other adverse effects. Postmarketing Antiepileptic Drug Survey (PADS) Group.
    Epilepsia, 1999, Volume: 40, Issue:8

    Topics: Adolescent; Adult; Child; Dizziness; Drug Eruptions; Drug Hypersensitivity; Drug Therapy, Combinatio

1999

Other Studies

3 other studies available for lamotrigine and Sleep Initiation and Maintenance Disorders

ArticleYear
Lamotrigine associated with insomnia.
    Epilepsia, 1999, Volume: 40, Issue:3

    Topics: Adult; Anticonvulsants; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Incidence; Lamot

1999
Re: Sadler's article regarding lamotrigine-associated insomnia in an adult tertiary care epilepsy out-patient clinic.
    Epilepsia, 2000, Volume: 41, Issue:7

    Topics: Adult; Anticonvulsants; Child; Epilepsy; Female; Humans; Lamotrigine; Melatonin; Sleep Initiation an

2000
The effects of lamotrigine on sleep in patients with epilepsy.
    Epilepsia, 2001, Volume: 42, Issue:12

    Topics: Adult; Anticonvulsants; Cohort Studies; Epilepsy; Female; Humans; Lamotrigine; Male; Middle Aged; Po

2001