lamotrigine has been researched along with Serotonin Syndrome in 3 studies
Serotonin Syndrome: An adverse drug interaction characterized by altered mental status, autonomic dysfunction, and neuromuscular abnormalities. It is most frequently caused by use of both serotonin reuptake inhibitors and monoamine oxidase inhibitors, leading to excess serotonin availability in the CNS at the serotonin 1A receptor.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lamotrigine is a novel anticonvulsant drug which also stabilises mood in bipolar illness via an unknown mechanism." | 1.30 | Lamotrigine inhibits monoamine uptake in vitro and modulates 5-hydroxytryptamine uptake in rats. ( Hagan, RM; Higgins, GA; Kirkby, D; Southam, E, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dizdarevic, A | 1 |
| Bremer, N | 1 |
| Dagtekin, O | 1 |
| Marcus, H | 1 |
| Müller, C | 1 |
| Böttiger, BW | 1 |
| Spöhr, F | 1 |
| Southam, E | 1 |
| Kirkby, D | 1 |
| Higgins, GA | 1 |
| Hagan, RM | 1 |
3 other studies available for lamotrigine and Serotonin Syndrome
| Article | Year |
|---|---|
Cervical Spinal Cord Stimulation with Concomitant Serotonin Norepinephrine Reuptake Inhibitor Therapy Leading to the Serotonin Syndrome.
Topics: Adult; Analgesics; Cervical Vertebrae; Clonidine; Complex Regional Pain Syndromes; Diclofenac; Drug | 2017 |
Lipid therapy for serotonin syndrome after intoxication with venlafaxine, lamotrigine and diazepam.
Topics: Adult; Combined Modality Therapy; Cyclohexanols; Diazepam; Emulsions; Fat Emulsions, Intravenous; Fe | 2011 |
Lamotrigine inhibits monoamine uptake in vitro and modulates 5-hydroxytryptamine uptake in rats.
Topics: Acetates; Amines; Animals; Anticonvulsants; Biogenic Amines; Blood Platelets; Brain; Carbamazepine; | 1998 |