lamotrigine has been researched along with Rett Syndrome in 7 studies
Rett Syndrome: An inherited neurological developmental disorder that is associated with X-LINKED INHERITANCE and may be lethal in utero to hemizygous males. The affected female is normal until the age of 6-25 months when progressive loss of voluntary control of hand movements and communication skills; ATAXIA; SEIZURES; autistic behavior; intermittent HYPERVENTILATION; and HYPERAMMONEMIA appear. (From Menkes, Textbook of Child Neurology, 5th ed, p199)
| Excerpt | Relevance | Reference |
|---|---|---|
| "This open pilot study was performed to evaluate the effect of Lamotrigine (LTG) in girls with Rett syndrome (RS) regarding seizure frequency, effect on gross motor dyspraxia and safety." | 9.08 | Lamotrigine in Rett syndrome: treatment experience from a pilot study. ( Hagberg, B; Stenbom, Y; Tonnby, B, 1998) |
| "Lamotrigine was used in the treatment of the convulsions." | 5.31 | Lamotrigine in two cases of Rett syndrome. ( Caksen, H; Ciftçi, A; Kumandas, S; Oztürk, M; Per, H, 2001) |
| "This open pilot study was performed to evaluate the effect of Lamotrigine (LTG) in girls with Rett syndrome (RS) regarding seizure frequency, effect on gross motor dyspraxia and safety." | 5.08 | Lamotrigine in Rett syndrome: treatment experience from a pilot study. ( Hagberg, B; Stenbom, Y; Tonnby, B, 1998) |
| " VPA and CBZ proved to be equally effective in Rett patients who presented seizures within the typical age range (4-5 years), while Lamotrigine (LTG) was effective for patients in whom epilepsy started later." | 3.81 | Antiepileptic drugs in Rett Syndrome. ( Baglietto, MG; Calevo, MG; Canevini, M; Giacomini, T; Giordano, L; Hayek, Y; Pintaudi, M; Renieri, A; Russo, S; Traverso, M; Veneselli, E; Vignoli, A, 2015) |
| "Valproic acid (VPA) was the most prescribed single therapy in young patients (<15years), whereas carbamazepine (CBZ) was preferred by clinicians in older patients." | 1.46 | Effectiveness and tolerability of antiepileptic drugs in 104 girls with Rett syndrome. ( Canevini, MP; La Briola, F; Nowbut, MS; Peron, A; Savini, MN; Turner, K; Vignoli, A, 2017) |
| "Lamotrigine was used in the treatment of the convulsions." | 1.31 | Lamotrigine in two cases of Rett syndrome. ( Caksen, H; Ciftçi, A; Kumandas, S; Oztürk, M; Per, H, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pintaudi, M | 1 |
| Calevo, MG | 1 |
| Vignoli, A | 2 |
| Baglietto, MG | 1 |
| Hayek, Y | 1 |
| Traverso, M | 1 |
| Giacomini, T | 1 |
| Giordano, L | 1 |
| Renieri, A | 1 |
| Russo, S | 1 |
| Canevini, M | 1 |
| Veneselli, E | 1 |
| Savini, MN | 1 |
| Nowbut, MS | 1 |
| Peron, A | 1 |
| Turner, K | 1 |
| La Briola, F | 1 |
| Canevini, MP | 1 |
| Rana, KS | 1 |
| Nair, MN | 1 |
| Mendhekar, DN | 1 |
| Duggal, HS | 1 |
| Uldall, P | 1 |
| Hansen, FJ | 1 |
| Tonnby, B | 2 |
| Stenbom, Y | 1 |
| Hagberg, B | 1 |
| Kumandas, S | 1 |
| Caksen, H | 1 |
| Ciftçi, A | 1 |
| Oztürk, M | 1 |
| Per, H | 1 |
1 trial available for lamotrigine and Rett Syndrome
| Article | Year |
|---|---|
Lamotrigine in Rett syndrome: treatment experience from a pilot study.
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Epilepsy; Female; Humans; Incidence; La | 1998 |
6 other studies available for lamotrigine and Rett Syndrome
| Article | Year |
|---|---|
Antiepileptic drugs in Rett Syndrome.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Lamotrigine; Male | 2015 |
Effectiveness and tolerability of antiepileptic drugs in 104 girls with Rett syndrome.
Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Therap | 2017 |
Rett's syndrome following bronchopneumonia.
Topics: Bronchopneumonia; Carnitine; Child, Preschool; Drug Therapy, Combination; Electroencephalography; Fe | 2004 |
Acquired variant of Rett's disorder and response to lamotrigine.
Topics: Adrenergic alpha-Antagonists; Child, Preschool; Clonidine; Encephalitis; Excitatory Amino Acid Antag | 2007 |
Lamotrigine in Rett syndrome.
Topics: Adult; Anticonvulsants; Cerebrospinal Fluid; Child; Child, Preschool; Epilepsy; Female; Glutamates; | 1993 |
Lamotrigine in two cases of Rett syndrome.
Topics: Anticonvulsants; Child, Preschool; Female; Humans; Lamotrigine; Rett Syndrome; Triazines | 2001 |