lamotrigine has been researched along with Recrudescence in 36 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "In the present study, an effort was made to investigate the effect of lamotrigine on cognitive function and serum inflammatory factors in patients with depression of recurrent bipolar disorder and to explore its possible mechanism." | 9.27 | Effect of lamotrigine on cognitive function and serum inflammatory factors in patients with depression of recurrent bipolar disorder. ( Li, L; Shi, S; Song, L; Wang, X, 2018) |
| "Whether patients with adult bipolar disorder (BD) who have been clinically stabilized with lithium or lamotrigine should continue this medication is not established fully." | 9.01 | Efficacy and safety of lithium and lamotrigine for the maintenance treatment of clinically stable patients with bipolar disorder: A systematic review and meta-analysis of double-blind, randomized, placebo-controlled trials with an enrichment design. ( Esumi, S; Hashimoto, R; Hashimoto, Y; Hatano, M; Iwata, N; Kato, M; Kishi, T; Matsuda, Y; Matsui, Y; Mishima, K; Miyake, N; Nomura, I; Okuya, M; Oya, K; Sakuma, K; Watanabe, N, 2019) |
| "Lamotrigine is being prescribed increasingly for the treatment of bipolar disorder." | 8.84 | [Lamotrigine in the treatment of bipolar disorder, a review]. ( Knoppert-van der Klein, EA; Kölling, P; Nolen, WA; van der Loos, ML, 2007) |
| "Both patients with SUNCT syndrome were successfully treated with lamotrigine." | 7.71 | SUNCT syndrome responsive to lamotrigine. ( Gutierrez-Garcia, JM, 2002) |
| "In the present study, an effort was made to investigate the effect of lamotrigine on cognitive function and serum inflammatory factors in patients with depression of recurrent bipolar disorder and to explore its possible mechanism." | 5.27 | Effect of lamotrigine on cognitive function and serum inflammatory factors in patients with depression of recurrent bipolar disorder. ( Li, L; Shi, S; Song, L; Wang, X, 2018) |
| "Whether patients with adult bipolar disorder (BD) who have been clinically stabilized with lithium or lamotrigine should continue this medication is not established fully." | 5.01 | Efficacy and safety of lithium and lamotrigine for the maintenance treatment of clinically stable patients with bipolar disorder: A systematic review and meta-analysis of double-blind, randomized, placebo-controlled trials with an enrichment design. ( Esumi, S; Hashimoto, R; Hashimoto, Y; Hatano, M; Iwata, N; Kato, M; Kishi, T; Matsuda, Y; Matsui, Y; Mishima, K; Miyake, N; Nomura, I; Okuya, M; Oya, K; Sakuma, K; Watanabe, N, 2019) |
| "Lamotrigine is being prescribed increasingly for the treatment of bipolar disorder." | 4.84 | [Lamotrigine in the treatment of bipolar disorder, a review]. ( Knoppert-van der Klein, EA; Kölling, P; Nolen, WA; van der Loos, ML, 2007) |
| "Lamotrigine and lithium were superior to placebo for time to intervention for any mood episode (median survival: placebo, 86 days [95% CI = 58 to 121]; lithium, 184 days [95% CI = 119 to not calculable]; lamotrigine, 197 days [95% CI = 144 to 388])." | 3.81 | A pooled analysis of 2 placebo-controlled 18-month trials of lamotrigine and lithium maintenance in bipolar I disorder. ( Bowden, CL; Calabrese, JR; Goodwin, GM; Greene, P; Grunze, H; Kasper, S; Leadbetter, R; White, R, 2004) |
| "Previous studies have demonstrated that the pharmacokinetics of the new antiepileptic drug (AED) lamotrigine (LTG) are substantially influenced by pregnancy and are more likely to be associated with seizure deterioration in pregnancy compared to other AEDs." | 3.75 | Seizure frequency in pregnant women treated with lamotrigine monotherapy. ( Petrenaite, V; Sabers, A, 2009) |
| "The authors describe 12 pregnancies in women with epilepsy using lamotrigine (LTG) monotherapy." | 3.72 | Gestation-induced changes in lamotrigine pharmacokinetics: a monotherapy study. ( Augustijn, P; de Haan, GJ; Dévilé-Notschaele, M; Edelbroek, P; Engelsman, M; Lindhout, D; Segers, J, 2004) |
| "Both patients with SUNCT syndrome were successfully treated with lamotrigine." | 3.71 | SUNCT syndrome responsive to lamotrigine. ( Gutierrez-Garcia, JM, 2002) |
| "Seizure freedom (SF) was defined as no seizure recurrence during the 40-week maintenance period of medication." | 2.80 | The effect of recurrent seizures on cognitive, behavioral, and quality-of-life outcomes after 12 months of monotherapy in adults with newly diagnosed or previously untreated partial epilepsy. ( Heo, K; Kim, MJ; Kim, OJ; Kim, SO; Lee, BI; Lee, HW; Lee, SA; Shin, DJ; Song, HK, 2015) |
| " Patients (n = 204) received lamotrigine according to a dosing schedule that depended on prior experience with lamotrigine and concurrent antiepileptic drug therapy for up to 48 weeks or their second birthday, whichever occurred last." | 2.73 | Long-term tolerability and efficacy of lamotrigine in infants 1 to 24 months old. ( Ayala, R; Conklin, HS; Corral, M; Elterman, RD; Messenheimer, JA; Mikati, MA; Piña-Garza, JE; Piña-Garza, MJ; Warnock, CR, 2008) |
| " For optimal dosing in pregnancy, therapeutic drug monitoring may be required to maintain effective drug concentrations." | 2.58 | Treatment of Peripartum Bipolar Disorder. ( Clark, CT; Wisner, KL, 2018) |
| "Lamotrigine was significantly less likely to be withdrawn than carbamazepine but the results for time to first seizure suggested that carbamazepine may be superior in terms of seizure control." | 2.53 | Lamotrigine versus carbamazepine monotherapy for epilepsy: an individual participant data review. ( Marson, AG; Nolan, SJ; Tudur Smith, C; Weston, J, 2016) |
| "However, the treatment of bipolar depression is hampered by the limited number and varying quality of available studies of pharmacologic treatments to guide clinical decision making." | 2.43 | The evidence for antidepressant use in bipolar depression. ( Ostacher, MJ, 2006) |
| "Although antiepileptic drugs (AEDs) are commonly used to control and prevent seizures, their long-term use carries a considerable risk of morbidity." | 2.41 | Antiepileptic drug therapy for adults: when to initiate and how to choose. ( Sirven, JI, 2002) |
| "Lamotrigine is an anticonvulsant with antidepressant properties, and reported effectiveness in bipolar depression." | 1.34 | Lamotrigine in the treatment of recurrent brief depression. ( Ravindran, AV; Ravindran, LN, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (8.33) | 18.2507 |
| 2000's | 21 (58.33) | 29.6817 |
| 2010's | 11 (30.56) | 24.3611 |
| 2020's | 1 (2.78) | 2.80 |
| Authors | Studies |
|---|---|
| Fico, G | 1 |
| Anmella, G | 1 |
| Sagué-Villavella, M | 1 |
| Gomez-Ramiro, M | 1 |
| Hidalgo-Mazzei, D | 1 |
| Vieta, E | 2 |
| Murru, A | 1 |
| Iriki, H | 1 |
| Ouchi, T | 1 |
| Ito, H | 1 |
| Sawada, M | 1 |
| Mukai, M | 1 |
| Nomura, H | 1 |
| Baba, Y | 1 |
| Adachi, T | 1 |
| Funakoshi, T | 1 |
| Amagai, M | 1 |
| Takahashi, H | 1 |
| Nevitt, SJ | 1 |
| Tudur Smith, C | 2 |
| Weston, J | 2 |
| Marson, AG | 2 |
| Clark, CT | 1 |
| Wisner, KL | 1 |
| Shi, S | 1 |
| Li, L | 1 |
| Song, L | 1 |
| Wang, X | 1 |
| Oya, K | 1 |
| Sakuma, K | 1 |
| Esumi, S | 1 |
| Hashimoto, Y | 1 |
| Hatano, M | 1 |
| Matsuda, Y | 1 |
| Matsui, Y | 1 |
| Miyake, N | 1 |
| Nomura, I | 1 |
| Okuya, M | 1 |
| Iwata, N | 1 |
| Kato, M | 1 |
| Hashimoto, R | 1 |
| Mishima, K | 1 |
| Watanabe, N | 1 |
| Kishi, T | 1 |
| Ogawa, K | 1 |
| Iyoda, K | 1 |
| Rihmer, Z | 1 |
| Gonda, X | 1 |
| Kálmán, J | 1 |
| Lee, SA | 1 |
| Kim, MJ | 1 |
| Lee, HW | 1 |
| Heo, K | 1 |
| Shin, DJ | 1 |
| Song, HK | 1 |
| Kim, OJ | 1 |
| Kim, SO | 1 |
| Lee, BI | 1 |
| Krauß, M | 1 |
| Berkermann, H | 1 |
| Ghadimi, M | 1 |
| Gaedcke, J | 1 |
| Bürger, T | 1 |
| Nolan, SJ | 1 |
| Piña-Garza, JE | 1 |
| Elterman, RD | 1 |
| Ayala, R | 1 |
| Corral, M | 1 |
| Mikati, MA | 1 |
| Piña-Garza, MJ | 1 |
| Warnock, CR | 1 |
| Conklin, HS | 1 |
| Messenheimer, JA | 1 |
| Frye, MA | 4 |
| Yatham, L | 1 |
| Ketter, TA | 3 |
| Goldberg, J | 1 |
| Suppes, T | 3 |
| Calabrese, JR | 5 |
| Bowden, CL | 3 |
| Bourne, E | 1 |
| Bahn, RS | 1 |
| Adams, B | 1 |
| Boot, B | 1 |
| Sabers, A | 1 |
| Petrenaite, V | 1 |
| Gao, K | 1 |
| Kemp, DE | 2 |
| Ganocy, SJ | 1 |
| Muzina, DJ | 1 |
| Xia, G | 1 |
| Findling, RL | 1 |
| Parikh, SV | 1 |
| LeBlanc, SR | 1 |
| Ovanessian, MM | 1 |
| Gutierrez-Garcia, JM | 1 |
| Sirven, JI | 1 |
| Post, RM | 2 |
| Leverich, GS | 2 |
| Nolen, WA | 2 |
| Kupka, RW | 1 |
| Altshuler, LL | 1 |
| McElroy, S | 1 |
| Keck, P | 1 |
| Grunze, H | 2 |
| Walden, J | 1 |
| Goodwin, GM | 1 |
| Kasper, S | 1 |
| White, R | 1 |
| Greene, P | 1 |
| Leadbetter, R | 1 |
| Verrotti, A | 1 |
| Latini, G | 1 |
| Giannuzzi, R | 1 |
| Cutarella, R | 1 |
| Trotta, D | 1 |
| Morgese, G | 1 |
| Chiarelli, F | 1 |
| de Haan, GJ | 1 |
| Edelbroek, P | 1 |
| Segers, J | 1 |
| Engelsman, M | 1 |
| Lindhout, D | 1 |
| Dévilé-Notschaele, M | 1 |
| Augustijn, P | 1 |
| Kilfoyle, DH | 1 |
| Anderson, NE | 1 |
| Wallis, WE | 1 |
| Nicholls, DW | 1 |
| Crevits, L | 1 |
| Colom, F | 1 |
| Daban, C | 1 |
| Pacchiarotti, I | 1 |
| Sánchez-Moreno, J | 1 |
| Ostacher, MJ | 1 |
| Yatham, LN | 1 |
| Adams, BE | 1 |
| Thompson, TR | 1 |
| Gilmer, WS | 1 |
| Fleck, J | 1 |
| Dago, PL | 1 |
| van der Loos, ML | 1 |
| Kölling, P | 1 |
| Knoppert-van der Klein, EA | 1 |
| Ravindran, LN | 1 |
| Ravindran, AV | 1 |
| Tavernor, SJ | 1 |
| Wong, IC | 1 |
| Newton, R | 1 |
| Brown, SW | 1 |
| Stolarek, I | 1 |
| Blacklaw, J | 1 |
| Forrest, G | 1 |
| Brodie, MJ | 1 |
| Buzan, RD | 1 |
| Dubovsky, SL | 1 |
| Obrocea, GV | 1 |
| Dunn, RM | 1 |
| Luckenbaugh, DA | 1 |
| Speer, AM | 1 |
| Osuch, EA | 1 |
| Jajodia, K | 1 |
| Shelton, MD | 1 |
| Rapport, DJ | 1 |
| Kujawa, M | 1 |
| Kimmel, SE | 1 |
| Caban, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Safety and Effectiveness of Probiotic Supplementation on Bipolar Depression: a Proof of Concept Randomized Controlled Trial[NCT02155972] | Phase 2 | 16 participants (Actual) | Interventional | 2013-05-31 | Terminated (stopped due to The trial was terminated because of inability to recruit the needed number of participants) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
10 reviews available for lamotrigine and Recrudescence
| Article | Year |
|---|---|
Lamotrigine versus carbamazepine monotherapy for epilepsy: an individual participant data review.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Epilepsies, Partial; Epilepsy, Generalized; Epilepsy, | 2018 |
Treatment of Peripartum Bipolar Disorder.
Topics: Bipolar Disorder; Electroconvulsive Therapy; Female; Humans; Lamotrigine; Peripartum Period; Phototh | 2018 |
Efficacy and safety of lithium and lamotrigine for the maintenance treatment of clinically stable patients with bipolar disorder: A systematic review and meta-analysis of double-blind, randomized, placebo-controlled trials with an enrichment design.
Topics: Adult; Antipsychotic Agents; Bipolar Disorder; Depression; Double-Blind Method; Female; Humans; Lamo | 2019 |
Lamotrigine versus carbamazepine monotherapy for epilepsy: an individual participant data review.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Epilepsies, Partial; Epilepsy, Generalized; Epilepsy, | 2016 |
Antiepileptic drug therapy for adults: when to initiate and how to choose.
Topics: Acetates; Adult; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Felb | 2002 |
A re-evaluation of the role of antidepressants in the treatment of bipolar depression: data from the Stanley Foundation Bipolar Network.
Topics: Adult; Affect; Antidepressive Agents; Bipolar Disorder; Depressive Disorder; Double-Blind Method; Dr | 2003 |
A pooled analysis of 2 placebo-controlled 18-month trials of lamotrigine and lithium maintenance in bipolar I disorder.
Topics: Adult; Antimanic Agents; Bipolar Disorder; Clinical Trials as Topic; Diagnostic and Statistical Manu | 2004 |
The evidence for antidepressant use in bipolar depression.
Topics: Anticonvulsants; Antidepressive Agents; Bipolar Disorder; Critical Pathways; Depressive Disorder; Hu | 2006 |
[Lamotrigine in the treatment of bipolar disorder, a review].
Topics: Antimanic Agents; Bipolar Disorder; Calcium Channel Blockers; Evidence-Based Medicine; Humans; Lamot | 2007 |
Current research on rapid cycling bipolar disorder and its treatment.
Topics: Acute Disease; Antimanic Agents; Bipolar Disorder; Carbamazepine; Drug Administration Schedule; Drug | 2001 |
8 trials available for lamotrigine and Recrudescence
| Article | Year |
|---|---|
Effect of lamotrigine on cognitive function and serum inflammatory factors in patients with depression of recurrent bipolar disorder.
Topics: Adult; Anticonvulsants; Bipolar Disorder; Cognition; Female; Humans; Inflammation Mediators; Interle | 2018 |
[Treatment of bipolar disorder with lamotrigine -- relapse rate and suicidal behaviour during 6 month follow-up].
Topics: Adult; Ambulatory Care; Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Bipolar Disord | 2015 |
The effect of recurrent seizures on cognitive, behavioral, and quality-of-life outcomes after 12 months of monotherapy in adults with newly diagnosed or previously untreated partial epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Cognition; Epilepsies, Partial; Female; Follow-Up Studies; Hu | 2015 |
Long-term tolerability and efficacy of lamotrigine in infants 1 to 24 months old.
Topics: Anticonvulsants; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule | 2008 |
A pooled analysis of 2 placebo-controlled 18-month trials of lamotrigine and lithium maintenance in bipolar I disorder.
Topics: Adult; Antimanic Agents; Bipolar Disorder; Clinical Trials as Topic; Diagnostic and Statistical Manu | 2004 |
Factors associated with poor control in partial complex epilepsy.
Topics: Age of Onset; Anticonvulsants; Carbamazepine; Child; Drug Therapy, Combination; Electroencephalograp | 2004 |
Vigabatrin and lamotrigine in refractory epilepsy.
Topics: Anticonvulsants; Double-Blind Method; Drug Monitoring; Drug Therapy, Combination; Epilepsy, Complex | 1994 |
Clinical predictors of response to lamotrigine and gabapentin monotherapy in refractory affective disorders.
Topics: Acetates; Adult; Aged; Amines; Antidepressive Agents; Cross-Over Studies; Cross-Sectional Studies; C | 2002 |
19 other studies available for lamotrigine and Recrudescence
| Article | Year |
|---|---|
Undetermined predominant polarity in a cohort of bipolar disorder patients: Prevalent, severe, and overlooked.
Topics: Bipolar Disorder; Cohort Studies; Humans; Lamotrigine; Recurrence | 2022 |
Case of lamotrigine-induced drug adverse reaction under tocilizumab treatment with clinical and virological features of drug-induced hypersensitivity syndrome.
Topics: Adult; Antibodies, Monoclonal, Humanized; Anticonvulsants; Arthritis, Rheumatoid; Biopsy; C-Reactive | 2018 |
[The effectiveness of lamotrigine in a case of ring chromosome 14 with refractory epilepsy].
Topics: Anticonvulsants; Brain Waves; Child, Preschool; Chromosomes, Human, Pair 14; Developmental Disabilit | 2013 |
[Recurrent seizures of unknown aetiology].
Topics: Adult; Amnesia; Anticonvulsants; C-Peptide; Confusion; Endosonography; Female; Glucose Tolerance Tes | 2016 |
Depressive relapse during lithium treatment associated with increased serum thyroid-stimulating hormone: results from two placebo-controlled bipolar I maintenance studies.
Topics: Adult; Affect; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Double-Blind Method; Humans; Lam | 2009 |
Recurrent lamotrigine-induced aseptic meningitis.
Topics: Adult; Female; Humans; Lamotrigine; Meningitis, Aseptic; Recurrence; Triazines | 2009 |
Seizure frequency in pregnant women treated with lamotrigine monotherapy.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Cohort Studies; Dose-Response Relationship, Dru | 2009 |
Treatment-emergent mania/hypomania during antidepressant monotherapy in patients with rapid cycling bipolar disorder.
Topics: Adult; Affect; Anticonvulsants; Antidepressive Agents, Second-Generation; Antimanic Agents; Bipolar | 2008 |
Advancing bipolar disorder: key lessons from the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD).
Topics: Anticonvulsants; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Anxiety Disorders; | 2010 |
SUNCT syndrome responsive to lamotrigine.
Topics: Adult; Analgesics; Anticonvulsants; Conjunctiva; Female; Headache Disorders; Humans; Lamotrigine; Ma | 2002 |
Gestation-induced changes in lamotrigine pharmacokinetics: a monotherapy study.
Topics: Adult; Anticonvulsants; Cohort Studies; Dose-Response Relationship, Drug; Epilepsy; Female; Fetal Bl | 2004 |
Recurrent severe aseptic meningitis after exposure to lamotrigine in a patient with systemic lupus erythematosus.
Topics: Adolescent; Anticonvulsants; Comorbidity; Epilepsy, Generalized; Female; Humans; Lamotrigine; Lupus | 2005 |
Brachioradial pruritus--a peculiar neuropathic disorder.
Topics: Arm; Brachial Plexus Neuritis; Cervical Vertebrae; Female; Humans; Lamotrigine; Middle Aged; Pruritu | 2006 |
Clinical and therapeutic implications of predominant polarity in bipolar disorder.
Topics: Adult; Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Cross-Sectio | 2006 |
Incidence and time course of subsyndromal symptoms in patients with bipolar I disorder: an evaluation of 2 placebo-controlled maintenance trials.
Topics: Adult; Antimanic Agents; Bipolar Disorder; Comorbidity; Depression; Humans; Incidence; Lamotrigine; | 2006 |
An association of intrusive, repetitive phrases with lamotrigine treatment in bipolar II disorder.
Topics: Anticonvulsants; Bipolar Disorder; Delusions; Dose-Response Relationship, Drug; Drug Therapy, Combin | 2007 |
Lamotrigine in the treatment of recurrent brief depression.
Topics: Adult; Anticonvulsants; Antidepressive Agents; Depressive Disorder, Major; Humans; Lamotrigine; Male | 2007 |
Rechallenge with lamotrigine after initial rash.
Topics: Adolescent; Adult; Anticonvulsants; Child; Dose-Response Relationship, Drug; Drug Administration Sch | 1995 |
Recurrence of lamotrigine-associated rash with rechallenge.
Topics: Adult; Anticonvulsants; Bipolar Disorder; Drug Eruptions; Humans; Lamotrigine; Male; Obsessive-Compu | 1998 |