Page last updated: 2024-10-30

lamotrigine and Polycystic Ovary Syndrome

lamotrigine has been researched along with Polycystic Ovary Syndrome in 11 studies

Polycystic Ovary Syndrome: A complex disorder characterized by infertility, HIRSUTISM; OBESITY; and various menstrual disturbances such as OLIGOMENORRHEA; AMENORRHEA; ANOVULATION. Polycystic ovary syndrome is usually associated with bilateral enlarged ovaries studded with atretic follicles, not with cysts. The term, polycystic ovary, is misleading.

Research Excerpts

ExcerptRelevanceReference
"To evaluate development of components of polycystic ovary syndrome (PCOS) and PCOS in women with epilepsy initiating valproate or lamotrigine therapy."9.13Hyperandrogenism, ovulatory dysfunction, and polycystic ovary syndrome with valproate versus lamotrigine. ( Adams, JM; Bhatt, M; Hayes, FJ; Isojärvi, J; Morrell, MJ; Ozkara, C; Sluss, PM; Warnock, CR, 2008)
"To investigate the development of reproductive endocrine changes in Indian women with epilepsy initiating on either Valproate (VPA) or Lamotrigine (LTG) monotherapy."5.27Evaluate the effects of antiepileptic drugs on reproductive endocrine system in newly diagnosed female epileptic patients receiving either Valproate or Lamotrigine monotherapy: A prospective study. ( Sadhotra, A; Sidhu, HS; Srinivasa, R, 2018)
"To evaluate development of components of polycystic ovary syndrome (PCOS) and PCOS in women with epilepsy initiating valproate or lamotrigine therapy."5.13Hyperandrogenism, ovulatory dysfunction, and polycystic ovary syndrome with valproate versus lamotrigine. ( Adams, JM; Bhatt, M; Hayes, FJ; Isojärvi, J; Morrell, MJ; Ozkara, C; Sluss, PM; Warnock, CR, 2008)
"A group of 105 women (54 of whom were, and had only ever been, taking valproate for at least a year, and 51 who had only ever taken either lamotrigine or carbamazepine, for at least a year) were compared with a group of 50 women who did not have epilepsy: any oral contraceptive taken at the time of testing was recorded and blood levels of follicle stimulating hormone (FSH), luteinising hormone (LH), testosterone and prolactin were estimated from days 2 to 6 of the menstrual cycle (day 1 being the first day of bleeding) and an MRI scan made of their pelvis."3.72A study of anticonvulsant medication on ovarian function in a group of women with epilepsy who have only ever taken one anticonvulsant compared with a group of women without epilepsy. ( Betts, T; Dutton, N; Greenhill, L; Rolfe, T; Yarrow, H, 2003)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (9.09)18.2507
2000's8 (72.73)29.6817
2010's1 (9.09)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Ortiz Salas, PA1
Rodríguez, JH1
Florez, SJB1
Suarez, FE1
Sidhu, HS1
Srinivasa, R1
Sadhotra, A1
Morrell, MJ1
Hayes, FJ1
Sluss, PM1
Adams, JM1
Bhatt, M1
Ozkara, C1
Warnock, CR1
Isojärvi, J1
Betts, T2
Yarrow, H1
Dutton, N1
Greenhill, L1
Rolfe, T1
Schmitz, B1
Karlov, VA1
Flück, CE1
Yaworsky, DC1
Miller, WL1
Isojärvi, JI2
Rättyä, J1
Myllylä, VV1
Knip, M1
Koivunen, R1
Pakarinen, AJ1
Tekay, A1
Tapanainen, JS2
Stephen, LJ1
Kwan, P1
Shapiro, D1
Dominiczak, M1
Brodie, MJ1

Reviews

3 reviews available for lamotrigine and Polycystic Ovary Syndrome

ArticleYear
Polycystic ovary syndrome and the new antiepileptic drugs: A systematic review.
    Epilepsy research, 2022, Volume: 185

    Topics: Anticonvulsants; Cross-Sectional Studies; Female; Humans; Lamotrigine; Levetiracetam; Polycystic Ova

2022
[Lamotrigine in women with epilepsy. Review of present data].
    Der Nervenarzt, 2003, Volume: 74, Issue:10

    Topics: Abnormalities, Drug-Induced; Anticonvulsants; Contraceptives, Oral; Dose-Response Relationship, Drug

2003
[Therapy of epilepsy: current strategy and tactics].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2004, Volume: 104, Issue:8

    Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Age Factors; Anticonvulsants; Carbamazepine; Child;

2004

Trials

2 trials available for lamotrigine and Polycystic Ovary Syndrome

ArticleYear
Evaluate the effects of antiepileptic drugs on reproductive endocrine system in newly diagnosed female epileptic patients receiving either Valproate or Lamotrigine monotherapy: A prospective study.
    Epilepsy research, 2018, Volume: 139

    Topics: Adolescent; Adult; Anticonvulsants; Endocrine System; Epilepsy; Female; Follow-Up Studies; Hormones;

2018
Hyperandrogenism, ovulatory dysfunction, and polycystic ovary syndrome with valproate versus lamotrigine.
    Annals of neurology, 2008, Volume: 64, Issue:2

    Topics: Adolescent; Adult; Anovulation; Epilepsy; Female; Humans; Hyperandrogenism; Internationality; Lamotr

2008

Other Studies

6 other studies available for lamotrigine and Polycystic Ovary Syndrome

ArticleYear
A study of anticonvulsant medication on ovarian function in a group of women with epilepsy who have only ever taken one anticonvulsant compared with a group of women without epilepsy.
    Seizure, 2003, Volume: 12, Issue:6

    Topics: Anticonvulsants; Carbamazepine; Case-Control Studies; Epilepsy; Female; Follicle Stimulating Hormone

2003
Effects of anticonvulsants on human p450c17 (17alpha-hydroxylase/17,20 lyase) and 3beta-hydroxysteroid dehydrogenase type 2.
    Epilepsia, 2005, Volume: 46, Issue:3

    Topics: 17-Hydroxysteroid Dehydrogenases; Adrenal Cortex Hormones; Androgens; Anticonvulsants; Carbamazepine

2005
Valproate, lamotrigine, and insulin-mediated risks in women with epilepsy.
    Annals of neurology, 1998, Volume: 43, Issue:4

    Topics: Analysis of Variance; Anticonvulsants; Cholesterol, HDL; Epilepsy; Female; Follow-Up Studies; Humans

1998
Valproate, hyperandrogenism, and polycystic ovaries: a report of 3 cases.
    Archives of neurology, 2000, Volume: 57, Issue:7

    Topics: Adolescent; Adult; Anticonvulsants; Body Weight; Electroencephalography; Epilepsy; Female; Humans; H

2000
Case reports.
    Seizure, 2001, Volume: 10, Issue:3

    Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Anticonvulsants; Child; Diagnosis, Differential; Epileps

2001
Hormone profiles in young adults with epilepsy treated with sodium valproate or lamotrigine monotherapy.
    Epilepsia, 2001, Volume: 42, Issue:8

    Topics: Adult; Anticonvulsants; Blood Glucose; Body Mass Index; Comorbidity; Dehydroepiandrosterone; Epileps

2001