lamotrigine has been researched along with Obsessive-Compulsive Disorder in 16 studies
Obsessive-Compulsive Disorder: An anxiety disorder characterized by recurrent, persistent obsessions or compulsions. Obsessions are the intrusive ideas, thoughts, or images that are experienced as senseless or repugnant. Compulsions are repetitive and seemingly purposeful behavior which the individual generally recognizes as senseless and from which the individual does not derive pleasure although it may provide a release from tension.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present 16-week double-blind, randomized, placebo-controlled trial had the aim to explore the efficacy of lamotrigine add-on pharmacotherapy on clinical symptomatology and cognitive functioning in a sample of patients with treatment-resistant obsessive-compulsive disorder (OCD) receiving serotonin reuptake inhibitors (SRIs)." | 9.16 | Lamotrigine augmentation of serotonin reuptake inhibitors in treatment-resistant obsessive-compulsive disorder: a double-blind, placebo-controlled study. ( Abenavoli, E; Bruno, A; D'Arrigo, C; Di Nardo, F; Mallamace, D; Micò, U; Muscatello, MR; Pandolfo, G; Spina, E; Zoccali, RA, 2012) |
| "This study evaluated the efficacy and safety of lamotrigine in binge-eating disorder (BED) associated with obesity." | 9.14 | Lamotrigine in the treatment of binge-eating disorder with obesity: a randomized, placebo-controlled monotherapy trial. ( Guerdjikova, AI; Hudson, JI; Keck, PE; McElroy, SL; Nelson, E; Welge, JA, 2009) |
| "IntroductionLamotrigine is a commonly used drug in the treatment of bipolar disorder." | 7.91 | Lamotrigine-induced obsessive-compulsive disorder in patients with bipolar disorder. ( Doobay, M; Sharma, V, 2019) |
| "The present 16-week double-blind, randomized, placebo-controlled trial had the aim to explore the efficacy of lamotrigine add-on pharmacotherapy on clinical symptomatology and cognitive functioning in a sample of patients with treatment-resistant obsessive-compulsive disorder (OCD) receiving serotonin reuptake inhibitors (SRIs)." | 5.16 | Lamotrigine augmentation of serotonin reuptake inhibitors in treatment-resistant obsessive-compulsive disorder: a double-blind, placebo-controlled study. ( Abenavoli, E; Bruno, A; D'Arrigo, C; Di Nardo, F; Mallamace, D; Micò, U; Muscatello, MR; Pandolfo, G; Spina, E; Zoccali, RA, 2012) |
| "This study evaluated the efficacy and safety of lamotrigine in binge-eating disorder (BED) associated with obesity." | 5.14 | Lamotrigine in the treatment of binge-eating disorder with obesity: a randomized, placebo-controlled monotherapy trial. ( Guerdjikova, AI; Hudson, JI; Keck, PE; McElroy, SL; Nelson, E; Welge, JA, 2009) |
| "IntroductionLamotrigine is a commonly used drug in the treatment of bipolar disorder." | 3.91 | Lamotrigine-induced obsessive-compulsive disorder in patients with bipolar disorder. ( Doobay, M; Sharma, V, 2019) |
| "Memantine was found to be most effective augmentation agent for SRIs in OCD, followed by lamotrigine, ondansetron and granisetron with moderate certainty of evidence." | 3.01 | Pharmacological augmentation of serotonin reuptake inhibitors in patients with obsessive-compulsive disorder: A network meta-analysis. ( Maiti, R; Mishra, A; Mishra, BR; Srinivasan, A, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (6.25) | 18.2507 |
| 2000's | 6 (37.50) | 29.6817 |
| 2010's | 8 (50.00) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Maiti, R | 1 |
| Mishra, A | 1 |
| Srinivasan, A | 1 |
| Mishra, BR | 1 |
| Sharma, V | 1 |
| Doobay, M | 1 |
| Jaffe, RJ | 2 |
| Juneja, NS | 2 |
| Coffey, BJ | 1 |
| Szmulewicz, AG | 1 |
| Valerio, MP | 1 |
| Smith, JM | 1 |
| Naguy, A | 1 |
| Alamiri, B | 1 |
| Al-Khadhari, S | 1 |
| Francis, K | 1 |
| Uzun, O | 1 |
| Bisol, LW | 1 |
| Lara, DR | 1 |
| Moretti, M | 1 |
| Guerdjikova, AI | 1 |
| McElroy, SL | 1 |
| Welge, JA | 1 |
| Nelson, E | 1 |
| Keck, PE | 1 |
| Hudson, JI | 1 |
| Mahgoub, N | 1 |
| Asemota, B | 1 |
| Alexopoulos, GS | 1 |
| Bruno, A | 1 |
| Micò, U | 1 |
| Pandolfo, G | 1 |
| Mallamace, D | 1 |
| Abenavoli, E | 1 |
| Di Nardo, F | 1 |
| D'Arrigo, C | 1 |
| Spina, E | 1 |
| Zoccali, RA | 1 |
| Muscatello, MR | 1 |
| Egashira, N | 1 |
| Abe, M | 1 |
| Shirakawa, A | 1 |
| Niki, T | 1 |
| Mishima, K | 1 |
| Iwasaki, K | 1 |
| Oishi, R | 1 |
| Fujiwara, M | 1 |
| Ozkara, C | 1 |
| Ozmen, M | 1 |
| Erdogan, A | 1 |
| Yalug, I | 1 |
| Alkin, T | 1 |
| Onur, E | 1 |
| Ozerdem, A | 1 |
| Buzan, RD | 1 |
| Dubovsky, SL | 1 |
| Kumar, TC | 1 |
| Khanna, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Lamotrigine in the Treatment of Binge Eating Disorder Associated With Obesity: A Single-Center, Double-Blind, Placebo-Controlled, Flexible-Dose Study in Outpatients[NCT00277641] | Phase 3 | 70 participants (Anticipated) | Interventional | 2006-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for lamotrigine and Obsessive-Compulsive Disorder
| Article | Year |
|---|---|
Pharmacological augmentation of serotonin reuptake inhibitors in patients with obsessive-compulsive disorder: A network meta-analysis.
Topics: Bayes Theorem; Drug Therapy, Combination; Granisetron; Humans; Lamotrigine; Memantine; Network Meta- | 2023 |
[Trichotillomania and comorbidity--lamotrigine in a new perspective].
Topics: Adolescent; Adult; Antidepressive Agents; Antimanic Agents; Anxiety; Behavior, Addictive; Bipolar Di | 2008 |
2 trials available for lamotrigine and Obsessive-Compulsive Disorder
| Article | Year |
|---|---|
Lamotrigine in the treatment of binge-eating disorder with obesity: a randomized, placebo-controlled monotherapy trial.
Topics: Adolescent; Adult; Aged; Antimanic Agents; Body Mass Index; Bulimia Nervosa; Double-Blind Method; Fe | 2009 |
Lamotrigine augmentation of serotonin reuptake inhibitors in treatment-resistant obsessive-compulsive disorder: a double-blind, placebo-controlled study.
Topics: Adult; Aged; Anticonvulsants; Cognition; Double-Blind Method; Drug Resistance; Drug Therapy, Combina | 2012 |
12 other studies available for lamotrigine and Obsessive-Compulsive Disorder
| Article | Year |
|---|---|
Lamotrigine-induced obsessive-compulsive disorder in patients with bipolar disorder.
Topics: Adult; Antipsychotic Agents; Bipolar Disorder; Diagnostic and Statistical Manual of Mental Disorders | 2019 |
Fourteen-Pound Fluvoxamine-Associated Weight Gain in a Young Woman with Depression and Multiple Anxiety Symptoms.
Topics: Adult; Anti-Anxiety Agents; Antidepressive Agents; Antidepressive Agents, Second-Generation; Anxiety | 2018 |
Obsessive-compulsive symptoms in adjunctive therapy with lamotrigine in clozapine-medicated patients.
Topics: Adult; Antipsychotic Agents; Clozapine; Cross-Sectional Studies; Drug Therapy, Combination; Female; | 2015 |
Lamotrigine Augmentation in Treatment-Resistant Pediatric Obsessive-Compulsive Disorder with a 16 Month Follow-up.
Topics: Child; Drug Therapy, Combination; Follow-Up Studies; Humans; Lamotrigine; Male; Obsessive-Compulsive | 2016 |
Lamotrigine as an augmentation agent in treatment-resistant obsessive-compulsive disorder: a case report.
Topics: Anticonvulsants; Antidepressive Agents, Tricyclic; Clomipramine; Dose-Response Relationship, Drug; D | 2010 |
Improvement of obsessive-compulsive disorder with divalproex and lamotrigine in two patients with bipolar II disorder.
Topics: Adult; Anticonvulsants; Bipolar Disorder; Female; Humans; Lamotrigine; Male; Obsessive-Compulsive Di | 2009 |
The effect of riluzole augmentation in a patient with treatment-resistant obsessive-compulsive disorder, taking two other glutaminergic agents.
Topics: Adult; Clonazepam; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Fructose; GABA Modu | 2011 |
Effects of mood stabilizers on marble-burying behavior in mice: involvement of GABAergic system.
Topics: Animals; Antipsychotic Agents; Baclofen; Behavior, Animal; Bicuculline; Carbamazepine; Dose-Response | 2013 |
Topiramate related obsessive-compulsive disorder.
Topics: Adult; Anticonvulsants; Antidepressive Agents, Second-Generation; Carbamazepine; Citalopram; Dose-Re | 2005 |
Co-occurence of blepharospasm, tourettism and obsessive-compulsive symptoms during lamotrigine treatment.
Topics: Anticonvulsants; Blepharospasm; Female; Humans; Lamotrigine; Middle Aged; Obsessive-Compulsive Disor | 2007 |
Recurrence of lamotrigine-associated rash with rechallenge.
Topics: Adult; Anticonvulsants; Bipolar Disorder; Drug Eruptions; Humans; Lamotrigine; Male; Obsessive-Compu | 1998 |
Lamotrigine augmentation of serotonin re-uptake inhibitors in obsessive-compulsive disorder.
Topics: Antidepressive Agents; Clomipramine; Dose-Response Relationship, Drug; Humans; Lamotrigine; Obsessiv | 2000 |