Page last updated: 2024-10-30

lamotrigine and Nervous System Diseases

lamotrigine has been researched along with Nervous System Diseases in 11 studies

Nervous System Diseases: Diseases of the central and peripheral nervous system. This includes disorders of the brain, spinal cord, cranial nerves, peripheral nerves, nerve roots, autonomic nervous system, neuromuscular junction, and muscle.

Research Excerpts

ExcerptRelevanceReference
"To correlate lamotrigine (LTG) serum concentrations (levels) with tolerability in patients with epilepsy."8.82Correlating lamotrigine serum concentrations with tolerability in patients with epilepsy. ( Adams, DJ; Bazil, CW; Buchsbaum, R; Du, Y; Hager, M; Hirsch, LJ; Morrell, MJ; Resor, SR; Spencer, HT; Straka, T; Weintraub, D, 2004)
"Lamotrigine is a broad-spectrum antiepileptic drug, initially approved in 1994 for the adjunctive treatment of partial seizures in adults and for the generalized seizures of Lennox-Gastaut syndrome in pediatric (>2 years old) and adult populations."6.43Lamotrigine and its applications in the treatment of epilepsy and other neurological and psychiatric disorders. ( Arif, H; Hirsch, LJ; Malik, S, 2006)
"To correlate lamotrigine (LTG) serum concentrations (levels) with tolerability in patients with epilepsy."4.82Correlating lamotrigine serum concentrations with tolerability in patients with epilepsy. ( Adams, DJ; Bazil, CW; Buchsbaum, R; Du, Y; Hager, M; Hirsch, LJ; Morrell, MJ; Resor, SR; Spencer, HT; Straka, T; Weintraub, D, 2004)
"Lamotrigine is a broad-spectrum antiepileptic drug, initially approved in 1994 for the adjunctive treatment of partial seizures in adults and for the generalized seizures of Lennox-Gastaut syndrome in pediatric (>2 years old) and adult populations."2.43Lamotrigine and its applications in the treatment of epilepsy and other neurological and psychiatric disorders. ( Arif, H; Hirsch, LJ; Malik, S, 2006)
"Neuropathic cranial pain, i."2.42Neuropathic cranial pain. ( Annovazzi, PO; Colombo, B; Comi, G, 2003)
"Gabapentin has demonstrated efficacy, specifically in painful diabetic neuropathy and postherpetic neuralgia."2.41Use of anticonvulsants for treatment of neuropathic pain. ( Backonja, MM, 2002)
"Individuals treated with combined valproate-lamotrigine rarely present late adverse effects (unrelated to introduction and titration)."1.38Late adverse effects of the coadministration of valproate and lamotrigine. ( Moreira, B; Thome-Souza, S; Valente, KD, 2012)
" Concerning pharmacokinetic drug interactions, we conclude that lamotrigine can be safely combined with most psychotropic drugs."1.33Drug interactions between lamotrigine and psychoactive drugs: evidence from a therapeutic drug monitoring service. ( Reimers, A; Skogvoll, E; Spigset, O; Sund, JK, 2005)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (18.18)18.2507
2000's7 (63.64)29.6817
2010's2 (18.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Okumura, A1
Arai, E1
Kitamura, Y1
Abe, S1
Ikeno, M1
Fujimaki, T1
Yamamoto, T1
Shimizu, T1
Reimers, A2
Thome-Souza, S1
Moreira, B1
Valente, KD1
Backonja, MM1
Colombo, B1
Annovazzi, PO1
Comi, G1
Hirsch, LJ2
Weintraub, D1
Du, Y1
Buchsbaum, R1
Spencer, HT1
Hager, M1
Straka, T1
Bazil, CW1
Adams, DJ1
Resor, SR1
Morrell, MJ1
Skogvoll, E1
Sund, JK1
Spigset, O1
Malik, S1
Arif, H1
Moncada, CR1
Arvin, B1
Meldrum, BS1
Schulz, JB1
Matthews, RT1
Henshaw, DR1
Beal, MF1
Devulder, J1
De Laat, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Pilot Study of Prophylactic Management of Lamotrigine for Bipolar Disorder in Pregnant Women[NCT03774641]20 participants (Anticipated)Observational2018-12-03Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for lamotrigine and Nervous System Diseases

ArticleYear
Use of anticonvulsants for treatment of neuropathic pain.
    Neurology, 2002, Sep-10, Volume: 59, Issue:5 Suppl 2

    Topics: Acetates; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid;

2002
Neuropathic cranial pain.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2003, Volume: 24 Suppl 2

    Topics: Acetates; Amines; Analgesics; Analgesics, Non-Narcotic; Anticonvulsants; Antidepressive Agents, Tric

2003
Correlating lamotrigine serum concentrations with tolerability in patients with epilepsy.
    Neurology, 2004, Sep-28, Volume: 63, Issue:6

    Topics: Anticonvulsants; Dose-Response Relationship, Drug; Drug Eruptions; Drug Interactions; Drug Therapy,

2004
Lamotrigine and its applications in the treatment of epilepsy and other neurological and psychiatric disorders.
    Expert review of neurotherapeutics, 2006, Volume: 6, Issue:11

    Topics: Anticonvulsants; Antimanic Agents; Dose-Response Relationship, Drug; Epilepsy; Humans; Lamotrigine;

2006

Other Studies

7 other studies available for lamotrigine and Nervous System Diseases

ArticleYear
Epilepsy phenotypes in siblings with Norrie disease.
    Brain & development, 2015, Volume: 37, Issue:10

    Topics: Anticonvulsants; Blindness; Chromosomes, Human, X; Electroencephalography; Epilepsy; Eye Proteins; G

2015
Trends and changes in the clinical use of lamotrigine.
    Pharmacoepidemiology and drug safety, 2009, Volume: 18, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Child; Child, Preschool; Databases, Fac

2009
Late adverse effects of the coadministration of valproate and lamotrigine.
    Pediatric neurology, 2012, Volume: 47, Issue:1

    Topics: Adolescent; Anticonvulsants; Ataxia; Child; Drug Therapy, Combination; Epilepsy; Female; Headache; H

2012
Drug interactions between lamotrigine and psychoactive drugs: evidence from a therapeutic drug monitoring service.
    Journal of clinical psychopharmacology, 2005, Volume: 25, Issue:4

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anticonvulsants; Drug Interactions; Drug Mo

2005
The pyrimidine derivative BW 1003C87 protects against excitotoxic lesions induced by kainate in the rat striatum.
    Neuroscience letters, 1994, Sep-26, Volume: 179, Issue:1-2

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Hippocampus; Kai

1994
Neuroprotective strategies for treatment of lesions produced by mitochondrial toxins: implications for neurodegenerative diseases.
    Neuroscience, 1996, Volume: 71, Issue:4

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Anticonvulsants; Coenzymes; Cyclic N-Oxides; Dizocilpine Malea

1996
Lamotrigine in the treatment of chronic refractory neuropathic pain.
    Journal of pain and symptom management, 2000, Volume: 19, Issue:5

    Topics: Adult; Aged; Analgesics; Analgesics, Opioid; Chronic Disease; Drug Therapy, Combination; Female; Hum

2000