lamotrigine has been researched along with Nerve Pain in 28 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "To assess the analgesic efficacy of lamotrigine in the treatment of chronic neuropathic pain and fibromyalgia, and to evaluate adverse effects reported in the studies." | 8.89 | Lamotrigine for chronic neuropathic pain and fibromyalgia in adults. ( Derry, S; Moore, RA; Wiffen, PJ, 2013) |
| "Continuously administered intrathecal lamotrigine blocked the development of mechanical allodynia induced by SNL with suppression of microglial and astrocytic activation." | 7.79 | Intrathecal lamotrigine attenuates mechanical allodynia and suppresses microglial and astrocytic activation in a rat model of spinal nerve ligation. ( Choi, YS; Jun, IG; Kim, SH; Park, JY, 2013) |
| "Both patients with SUNCT syndrome were successfully treated with lamotrigine." | 7.71 | SUNCT syndrome responsive to lamotrigine. ( Gutierrez-Garcia, JM, 2002) |
| "We present six patients treated only with the new-generation anticonvulsant lamotrigine to define its sole effect on neuralgia after nerve section." | 7.71 | Lamotrigine monotherapy for control of neuralgia after nerve section. ( Dorn, C; Koch, H; Rumpold Seitlinger, G; Sandner-Kiesling, A; Schwarz, G, 2002) |
| "To assess the analgesic efficacy of lamotrigine in the treatment of chronic neuropathic pain and fibromyalgia, and to evaluate adverse effects reported in the studies." | 4.89 | Lamotrigine for chronic neuropathic pain and fibromyalgia in adults. ( Derry, S; Moore, RA; Wiffen, PJ, 2013) |
| " Multiple multicentre randomised controlled trials have shown clear efficacy of gabapentin and pregabalin for postherpetic neuralgia and painful diabetic neuropathy." | 4.84 | Antiepileptic drugs in the treatment of neuropathic pain. ( Eisenberg, E; Krivoy, N; River, Y; Shifrin, A, 2007) |
| "Continuously administered intrathecal lamotrigine blocked the development of mechanical allodynia induced by SNL with suppression of microglial and astrocytic activation." | 3.79 | Intrathecal lamotrigine attenuates mechanical allodynia and suppresses microglial and astrocytic activation in a rat model of spinal nerve ligation. ( Choi, YS; Jun, IG; Kim, SH; Park, JY, 2013) |
| " Oxcarbazepine and carbamazepine (3-100 mg x kg(-1)) did not affect mechanical hyperalgesia or tactile allodynia induced by partial sciatic nerve ligation in the rat following oral administration." | 3.72 | Comparative activity of the anti-convulsants oxcarbazepine, carbamazepine, lamotrigine and gabapentin in a model of neuropathic pain in the rat and guinea-pig. ( Bevan, S; Fox, A; Gentry, C; Kesingland, A; Patel, S, 2003) |
| "Both patients with SUNCT syndrome were successfully treated with lamotrigine." | 3.71 | SUNCT syndrome responsive to lamotrigine. ( Gutierrez-Garcia, JM, 2002) |
| "We present six patients treated only with the new-generation anticonvulsant lamotrigine to define its sole effect on neuralgia after nerve section." | 3.71 | Lamotrigine monotherapy for control of neuralgia after nerve section. ( Dorn, C; Koch, H; Rumpold Seitlinger, G; Sandner-Kiesling, A; Schwarz, G, 2002) |
| "Amitriptyline was administered orally at doses of 25, 50 and 100 mg once daily at night time, and lamotrigine was administered orally at doses of 25, 50 and 100 mg twice daily, both for 1 week by means of optional titration." | 2.84 | Effectiveness of amitriptyline and lamotrigine in traumatic spinal cord injury-induced neuropathic pain: a randomized longitudinal comparative study. ( Agarwal, N; Joshi, M, 2017) |
| "All nine drugs can relieve the pain of CPSP patients to different degrees; among them pregabalin and gabapentin have the most significant effect, and gabapentin and pregabalin also have the most adverse reactions." | 2.82 | Efficacy and safety of different antidepressants and anticonvulsants in central poststroke pain: A network meta-analysis and systematic review. ( Chen, KY; Li, RY, 2022) |
| "Patients (n=360 per study) with painful diabetic neuropathy were randomized to receive lamotrigine 200, 300, or 400 mg daily or placebo during the 19-week treatment phase, including a 7-week dose-escalation phase and a 12-week, fixed-dose maintenance phase." | 2.73 | Lamotrigine for treatment of pain associated with diabetic neuropathy: results of two randomized, double-blind, placebo-controlled studies. ( Blum, D; Corder, C; Grainger, J; Kirby, L; Quessy, S; Safirstein, B; Silver, M; Tuchman, M; Vinik, AI; White, J; Wilks, K, 2007) |
| "Lamotrigine was generally well tolerated." | 2.73 | Double-blind, placebo-controlled trial of lamotrigine in combination with other medications for neuropathic pain. ( Blum, D; Grainger, J; Hammer, AE; Quessy, S; Silver, M, 2007) |
| "Lamotrigine was well-tolerated and effective for HIV-associated neuropathic pain in patients receiving neurotoxic antiretroviral therapy." | 2.71 | Lamotrigine for HIV-associated painful sensory neuropathies: a placebo-controlled trial. ( Baird, BJ; Barrett, P; Clifford, D; Hammer, AE; McArthur, JC; Olney, R; Ross, D; Simpson, DM; So, Y, 2003) |
| "Lamotrigine was generally well tolerated." | 2.70 | Lamotrigine in spinal cord injury pain: a randomized controlled trial. ( Bach, FW; Finnerup, NB; Jensen, TS; Johannesen, IL; Sindrup, SH, 2002) |
| "Indomethacin is the best treatment both for HC and PH." | 2.55 | Therapeutical approaches to paroxysmal hemicrania, hemicrania continua and short lasting unilateral neuralgiform headache attacks: a critical appraisal. ( Baraldi, C; Cainazzo, MM; Guerzoni, S; Pellesi, L; Pini, LA, 2017) |
| "Lamotrigine is an antiepileptic drug that stabilizes neural membranes by blocking the activation of voltage-sensitive sodium channels and inhibiting the presynaptic release of glutamate." | 2.43 | Lamotrigine for neuropathic pain. ( Eisenberg, E; Krivoy, N; Shifrin, A, 2005) |
| " Further, the poor pharmacokinetic profile due to non-selective distribution to organs other than brain reduces the efficacy of dosage regimen." | 1.42 | Protein-functionalized PLGA nanoparticles of lamotrigine for neuropathic pain management. ( Kolate, A; Lalani, J; Lalani, R; Misra, A; Patil, S, 2015) |
| "Antiepileptics used for treating neuropathic pain have various actions including voltage-gated Na(+) and Ca(2+) channels, glutamate-receptor inhibition, and GABA(A)-receptor activation, while local anesthetics are also used to alleviate the pain." | 1.40 | Effects of various antiepileptics used to alleviate neuropathic pain on compound action potential in frog sciatic nerves: comparison with those of local anesthetics. ( Fujita, T; Hirakawa, N; Kumamoto, E; Ohtsubo, S; Sakaguchi, Y; Uemura, Y, 2014) |
| "Neuropathic pain is a chronic pain condition that occurs and persists in a heterogeneous group of etiologically different diseases characterized by a primary lesion or dysfunction of the peripheral or central nervous system." | 1.37 | Discovery of molecules for the treatment of neuropathic pain: synthesis, antiallodynic and antihyperalgesic activities of 5-(4-nitrophenyl)furoic-2-acid hydrazones. ( Arjun, M; Menon, N; Semwal, A; Sriram, D; Yogeeswari, P, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (10.71) | 18.2507 |
| 2000's | 14 (50.00) | 29.6817 |
| 2010's | 9 (32.14) | 24.3611 |
| 2020's | 2 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Drizin, I | 1 |
| Gregg, RJ | 1 |
| Scanio, MJ | 1 |
| Shi, L | 1 |
| Gross, MF | 1 |
| Atkinson, RN | 1 |
| Thomas, JB | 1 |
| Johnson, MS | 1 |
| Carroll, WA | 1 |
| Marron, BE | 1 |
| Chapman, ML | 1 |
| Liu, D | 1 |
| Krambis, MJ | 1 |
| Shieh, CC | 1 |
| Zhang, X | 1 |
| Hernandez, G | 1 |
| Gauvin, DM | 1 |
| Mikusa, JP | 1 |
| Zhu, CZ | 1 |
| Joshi, S | 1 |
| Honore, P | 1 |
| Marsh, KC | 1 |
| Roeloffs, R | 1 |
| Werness, S | 1 |
| Krafte, DS | 1 |
| Jarvis, MF | 1 |
| Faltynek, CR | 1 |
| Kort, ME | 1 |
| Yogeeswari, P | 1 |
| Menon, N | 1 |
| Semwal, A | 1 |
| Arjun, M | 1 |
| Sriram, D | 1 |
| Pergolizzi, JV | 1 |
| Gharibo, C | 1 |
| Magnusson, P | 1 |
| Breve, F | 1 |
| LeQuang, JA | 1 |
| Varrassi, G | 1 |
| Chen, KY | 1 |
| Li, RY | 1 |
| Baraldi, C | 1 |
| Pellesi, L | 1 |
| Guerzoni, S | 1 |
| Cainazzo, MM | 1 |
| Pini, LA | 1 |
| Yalın, OÖ | 1 |
| Uludüz, D | 1 |
| Özge, A | 1 |
| Wiffen, PJ | 1 |
| Derry, S | 1 |
| Moore, RA | 1 |
| Pulido Fontes, L | 1 |
| Mayor Gómez, S | 1 |
| Uemura, Y | 1 |
| Fujita, T | 1 |
| Ohtsubo, S | 1 |
| Hirakawa, N | 1 |
| Sakaguchi, Y | 1 |
| Kumamoto, E | 1 |
| Lalani, J | 1 |
| Patil, S | 1 |
| Kolate, A | 1 |
| Lalani, R | 1 |
| Misra, A | 1 |
| Agarwal, N | 1 |
| Joshi, M | 1 |
| Titlic, M | 1 |
| Jukic, I | 1 |
| Tonkic, A | 1 |
| Josipovic-Jelic, Z | 1 |
| Boschi, V | 1 |
| Mihalj, M | 1 |
| Punda, A | 1 |
| Choi, YS | 1 |
| Jun, IG | 1 |
| Kim, SH | 1 |
| Park, JY | 1 |
| Gutierrez-Garcia, JM | 1 |
| Sandner-Kiesling, A | 1 |
| Rumpold Seitlinger, G | 1 |
| Dorn, C | 1 |
| Koch, H | 1 |
| Schwarz, G | 1 |
| Erichsen, HK | 1 |
| Hao, JX | 1 |
| Xu, XJ | 1 |
| Blackburn-Munro, G | 1 |
| Simpson, DM | 2 |
| McArthur, JC | 2 |
| Olney, R | 2 |
| Clifford, D | 1 |
| So, Y | 1 |
| Ross, D | 1 |
| Baird, BJ | 1 |
| Barrett, P | 1 |
| Hammer, AE | 2 |
| Fox, A | 1 |
| Gentry, C | 1 |
| Patel, S | 1 |
| Kesingland, A | 1 |
| Bevan, S | 1 |
| Garry, EM | 1 |
| Delaney, A | 1 |
| Anderson, HA | 1 |
| Sirinathsinghji, EC | 1 |
| Clapp, RH | 1 |
| Martin, WJ | 1 |
| Kinchington, PR | 1 |
| Krah, DL | 1 |
| Abbadie, C | 1 |
| Fleetwood-Walker, SM | 1 |
| Eisenberg, E | 2 |
| Shifrin, A | 2 |
| Krivoy, N | 2 |
| Vinik, AI | 1 |
| Tuchman, M | 1 |
| Safirstein, B | 1 |
| Corder, C | 1 |
| Kirby, L | 1 |
| Wilks, K | 1 |
| Quessy, S | 2 |
| Blum, D | 2 |
| Grainger, J | 2 |
| White, J | 1 |
| Silver, M | 2 |
| River, Y | 1 |
| di Vadi, PP | 1 |
| Hamann, W | 1 |
| D'Andrea, G | 1 |
| Granella, F | 1 |
| Cadaldini, M | 1 |
| Khan, A | 1 |
| Godbold, J | 1 |
| Ebel-Frommer, K | 1 |
| Finnerup, NB | 1 |
| Sindrup, SH | 1 |
| Bach, FW | 1 |
| Johannesen, IL | 1 |
| Jensen, TS | 1 |
| Covington, EC | 1 |
7 reviews available for lamotrigine and Nerve Pain
| Article | Year |
|---|---|
Efficacy and safety of different antidepressants and anticonvulsants in central poststroke pain: A network meta-analysis and systematic review.
Topics: Amitriptyline; Anticonvulsants; Antidepressive Agents; Carbamazepine; Duloxetine Hydrochloride; Fluo | 2022 |
Therapeutical approaches to paroxysmal hemicrania, hemicrania continua and short lasting unilateral neuralgiform headache attacks: a critical appraisal.
Topics: Amines; Analgesics; Anticonvulsants; Cyclohexanecarboxylic Acids; Female; Fructose; Gabapentin; gamm | 2017 |
Lamotrigine for chronic neuropathic pain and fibromyalgia in adults.
Topics: Acute Disease; Adult; Analgesics; Anticonvulsants; Chronic Disease; Fibromyalgia; Humans; Lamotrigin | 2013 |
Lamotrigine in the treatment of pain syndromes and neuropathic pain.
Topics: Analgesics; Anticonvulsants; Humans; Lamotrigine; Neuralgia; Pain; Triazines | 2008 |
Lamotrigine for neuropathic pain.
Topics: Analgesics; Drug Interactions; Drug Therapy, Combination; Expert Testimony; Female; Humans; Lamotrig | 2005 |
Antiepileptic drugs in the treatment of neuropathic pain.
Topics: Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Ami | 2007 |
Anticonvulsants for neuropathic pain and detoxification.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Clonazepam; Cyclohexanecarboxylic Acids; Gabapenti | 1998 |
6 trials available for lamotrigine and Nerve Pain
| Article | Year |
|---|---|
Effectiveness of amitriptyline and lamotrigine in traumatic spinal cord injury-induced neuropathic pain: a randomized longitudinal comparative study.
Topics: Administration, Oral; Adolescent; Adult; Amitriptyline; Anticonvulsants; Antidepressive Agents, Tric | 2017 |
Lamotrigine for HIV-associated painful sensory neuropathies: a placebo-controlled trial.
Topics: Adult; Aged; Analgesics, Non-Narcotic; Anti-HIV Agents; Dideoxynucleosides; Double-Blind Method; Dru | 2003 |
Lamotrigine for treatment of pain associated with diabetic neuropathy: results of two randomized, double-blind, placebo-controlled studies.
Topics: Diabetic Neuropathies; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Lamotr | 2007 |
Double-blind, placebo-controlled trial of lamotrigine in combination with other medications for neuropathic pain.
Topics: Analgesics; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hyperalgesia; Lamotrigin | 2007 |
A placebo-controlled trial of lamotrigine for painful HIV-associated neuropathy.
Topics: Adult; Analgesics; Analysis of Variance; Double-Blind Method; Drug Eruptions; Exanthema; Female; HIV | 2000 |
Lamotrigine in spinal cord injury pain: a randomized controlled trial.
Topics: Adult; Analgesics; Cross-Over Studies; Double-Blind Method; Female; Humans; Lamotrigine; Male; Middl | 2002 |
15 other studies available for lamotrigine and Nerve Pain
| Article | Year |
|---|---|
Discovery of potent furan piperazine sodium channel blockers for treatment of neuropathic pain.
Topics: Analgesics, Non-Narcotic; Animals; Ether-A-Go-Go Potassium Channels; Furans; Humans; Male; Mice; Neu | 2008 |
Discovery of molecules for the treatment of neuropathic pain: synthesis, antiallodynic and antihyperalgesic activities of 5-(4-nitrophenyl)furoic-2-acid hydrazones.
Topics: Analgesics; Animals; Disease Models, Animal; Drug Discovery; Female; Furans; Humans; Hydrazones; Hyp | 2011 |
Pharmacotherapeutic management of trigeminal neuropathic pain: an update.
Topics: Anticonvulsants; Carbamazepine; Humans; Lamotrigine; Neuralgia; Trigeminal Neuralgia | 2022 |
Peripheral nerve blocks for the treatment of short-lasting unilateral neuralgiform headache with conjunctival injection and tearing (SUNCT) during pregnancy.
Topics: Adult; Anticonvulsants; Diagnosis, Differential; Female; Headache; Humans; Lamotrigine; Nerve Block; | 2018 |
SUNCT (Short-lasting unilateral neuralgiform headache attack with conjunctival injection and tearing) associated with pituitary lesion.
Topics: Excitatory Amino Acid Antagonists; Headache; Humans; Lamotrigine; Magnetic Resonance Imaging; Male; | 2015 |
Effects of various antiepileptics used to alleviate neuropathic pain on compound action potential in frog sciatic nerves: comparison with those of local anesthetics.
Topics: Action Potentials; Anesthetics, Local; Animals; Anticonvulsants; Bupivacaine; Carbamazepine; Humans; | 2014 |
Protein-functionalized PLGA nanoparticles of lamotrigine for neuropathic pain management.
Topics: Analgesics; Animals; Brain; Female; Lactic Acid; Lactoferrin; Lamotrigine; Ligands; Male; Mice; Nano | 2015 |
Intrathecal lamotrigine attenuates mechanical allodynia and suppresses microglial and astrocytic activation in a rat model of spinal nerve ligation.
Topics: Animals; Astrocytes; Disease Models, Animal; Hyperalgesia; Infusions, Spinal; Lamotrigine; Ligation; | 2013 |
SUNCT syndrome responsive to lamotrigine.
Topics: Adult; Analgesics; Anticonvulsants; Conjunctiva; Female; Headache Disorders; Humans; Lamotrigine; Ma | 2002 |
Lamotrigine monotherapy for control of neuralgia after nerve section.
Topics: Adult; Anticonvulsants; Autonomic Denervation; Female; Humans; Lamotrigine; Male; Middle Aged; Neura | 2002 |
A comparison of the antinociceptive effects of voltage-activated Na+ channel blockers in two rat models of neuropathic pain.
Topics: Analgesics; Analysis of Variance; Anesthetics, Local; Animals; Disease Models, Animal; Dose-Response | 2003 |
Comparative activity of the anti-convulsants oxcarbazepine, carbamazepine, lamotrigine and gabapentin in a model of neuropathic pain in the rat and guinea-pig.
Topics: Acetates; Amines; Animals; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Gabapentin; | 2003 |
Varicella zoster virus induces neuropathic changes in rat dorsal root ganglia and behavioral reflex sensitisation that is attenuated by gabapentin or sodium channel blocking drugs.
Topics: Amines; Animals; Anticonvulsants; Behavior, Animal; Cyclohexanecarboxylic Acids; Disease Models, Ani | 2005 |
The use of lamotrigine in neuropathic pain.
Topics: Analgesics; Humans; Lamotrigine; Male; Middle Aged; Neuralgia; Sodium Channel Blockers; Triazines | 1998 |
Possible usefulness of lamotrigine in the treatment of SUNCT syndrome.
Topics: Aged; Calcium Channel Blockers; Conjunctival Diseases; Dose-Response Relationship, Drug; Female; Hea | 1999 |