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lamotrigine and Nerve Degeneration

lamotrigine has been researched along with Nerve Degeneration in 6 studies

Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.

Research Excerpts

ExcerptRelevanceReference
"Lamotrigine had neuroprotective effects in a gerbil model of global cerebral ischemia."7.69Neuroprotective properties of the novel antiepileptic lamotrigine in a gerbil model of global cerebral ischemia. ( Beek, O; Cooper, BR; Dickerson, MC; Norton, R; Wiard, RP, 1995)
"Lamotrigine had neuroprotective effects in a gerbil model of global cerebral ischemia."3.69Neuroprotective properties of the novel antiepileptic lamotrigine in a gerbil model of global cerebral ischemia. ( Beek, O; Cooper, BR; Dickerson, MC; Norton, R; Wiard, RP, 1995)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's4 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Park, SH1
Seo, YH1
Moon, BH1
Choi, SH2
Kang, S1
Lee, KJ1
Lee, MS1
Chun, BG1
Shin, KH1
Cui, J1
Shao, L1
Young, LT1
Wang, JF1
Bechtold, DA1
Miller, SJ1
Dawson, AC1
Sun, Y1
Kapoor, R1
Berry, D1
Smith, KJ1
Kim, YJ1
Ko, HH1
Han, ES1
Lee, CS1
Wiard, RP1
Dickerson, MC1
Beek, O1
Norton, R1
Cooper, BR1
Connop, BP1
Boegman, RJ1
Beninger, RJ1
Jhamandas, K1

Other Studies

6 other studies available for lamotrigine and Nerve Degeneration

ArticleYear
Lamotrigine prevents MK801-induced alterations in early growth response factor-1 mRNA levels and immunoreactivity in the rat brain.
    European journal of pharmacology, 2008, Jul-28, Volume: 589, Issue:1-3

    Topics: Animals; Cerebral Cortex; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, D

2008
Role of glutathione in neuroprotective effects of mood stabilizing drugs lithium and valproate.
    Neuroscience, 2007, Feb-23, Volume: 144, Issue:4

    Topics: Animals; Antimanic Agents; Brain; Carbamazepine; Cell Death; Cell Line, Tumor; Cells, Cultured; Cere

2007
Axonal protection achieved in a model of multiple sclerosis using lamotrigine.
    Journal of neurology, 2006, Volume: 253, Issue:12

    Topics: Action Potentials; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Lamotrigine; M

2006
Lamotrigine inhibition of rotenone- or 1-methyl-4-phenylpyridinium-induced mitochondrial damage and cell death.
    Brain research bulletin, 2007, Mar-30, Volume: 71, Issue:6

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; Caspase 3; Cell Death; Cell Membrane Permeability;

2007
Neuroprotective properties of the novel antiepileptic lamotrigine in a gerbil model of global cerebral ischemia.
    Stroke, 1995, Volume: 26, Issue:3

    Topics: Animals; Anticonvulsants; Arterial Occlusive Diseases; Behavior, Animal; Brain Chemistry; Brain Isch

1995
Malonate-induced degeneration of basal forebrain cholinergic neurons: attenuation by lamotrigine, MK-801, and 7-nitroindazole.
    Journal of neurochemistry, 1997, Volume: 68, Issue:3

    Topics: Animals; Dizocilpine Maleate; Enzyme Inhibitors; Indazoles; Lamotrigine; Male; Malonates; Nerve Dege

1997