Page last updated: 2024-10-30

lamotrigine and Multiple Sclerosis, Chronic Progressive

lamotrigine has been researched along with Multiple Sclerosis, Chronic Progressive in 4 studies

Multiple Sclerosis, Chronic Progressive: A form of multiple sclerosis characterized by a progressive deterioration in neurologic function which is in contrast to the more typical relapsing remitting form. If the clinical course is free of distinct remissions, it is referred to as primary progressive multiple sclerosis. When the progressive decline is punctuated by acute exacerbations, it is referred to as progressive relapsing multiple sclerosis. The term secondary progressive multiple sclerosis is used when relapsing remitting multiple sclerosis evolves into the chronic progressive form. (From Ann Neurol 1994;36 Suppl:S73-S79; Adams et al., Principles of Neurology, 6th ed, pp903-914)

Research Excerpts

ExcerptRelevanceReference
" We report 11 MS patients with trigeminal neuralgia (TN): 6 intolerant to a therapeutic dosage of CBZ, showing serious adverse effects and subsequently treated with a combination of low-dose CBZ and gabapentin (GBP) (group 1); 5 treated with lamotrigine (LMT), showing adverse effects and subsequently treated with GBP (group 2)."7.70Low-dose gabapentin combined with either lamotrigine or carbamazepine can be useful therapies for trigeminal neuralgia in multiple sclerosis. ( Leandri, M; Mancardi, GL; Messmer Uccelli, M; Solaro, C; Uccelli, A, 2000)
" We report 11 MS patients with trigeminal neuralgia (TN): 6 intolerant to a therapeutic dosage of CBZ, showing serious adverse effects and subsequently treated with a combination of low-dose CBZ and gabapentin (GBP) (group 1); 5 treated with lamotrigine (LMT), showing adverse effects and subsequently treated with GBP (group 2)."3.70Low-dose gabapentin combined with either lamotrigine or carbamazepine can be useful therapies for trigeminal neuralgia in multiple sclerosis. ( Leandri, M; Mancardi, GL; Messmer Uccelli, M; Solaro, C; Uccelli, A, 2000)
"Treatment with lamotrigine was associated with more rashes (20% vs 5%, P value 0."2.52Sodium channel blockers for neuroprotection in multiple sclerosis. ( Hao, Z; Wen, J; Yang, C; Zeng, L; Zhang, L, 2015)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yang, C1
Hao, Z1
Zhang, L1
Zeng, L1
Wen, J1
Hayton, T2
Furby, J2
Smith, KJ2
Altmann, DR2
Brenner, R2
Chataway, J2
Hunter, K2
Tozer, DJ2
Miller, DH2
Kapoor, R2
Solaro, C1
Messmer Uccelli, M1
Uccelli, A1
Leandri, M1
Mancardi, GL1

Reviews

1 review available for lamotrigine and Multiple Sclerosis, Chronic Progressive

ArticleYear
Sodium channel blockers for neuroprotection in multiple sclerosis.
    The Cochrane database of systematic reviews, 2015, 10-21, Issue:10

    Topics: Disease Progression; Female; Humans; Immunosuppressive Agents; Lamotrigine; Male; Middle Aged; Multi

2015

Trials

1 trial available for lamotrigine and Multiple Sclerosis, Chronic Progressive

ArticleYear
Longitudinal changes in magnetisation transfer ratio in secondary progressive multiple sclerosis: data from a randomised placebo controlled trial of lamotrigine.
    Journal of neurology, 2012, Volume: 259, Issue:3

    Topics: Adult; Calcium Channel Blockers; Disability Evaluation; Double-Blind Method; Female; Humans; Lamotri

2012

Other Studies

2 other studies available for lamotrigine and Multiple Sclerosis, Chronic Progressive

ArticleYear
Clinical and imaging correlates of the multiple sclerosis impact scale in secondary progressive multiple sclerosis.
    Journal of neurology, 2012, Volume: 259, Issue:2

    Topics: Adult; Anticonvulsants; Cross-Sectional Studies; Disability Evaluation; Double-Blind Method; Female;

2012
Low-dose gabapentin combined with either lamotrigine or carbamazepine can be useful therapies for trigeminal neuralgia in multiple sclerosis.
    European neurology, 2000, Volume: 44, Issue:1

    Topics: Acetates; Adult; Aged; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Dose-Res

2000