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lamotrigine and Migraine Disorders

lamotrigine has been researched along with Migraine Disorders in 16 studies

Migraine Disorders: A class of disabling primary headache disorders, characterized by recurrent unilateral pulsatile headaches. The two major subtypes are common migraine (without aura) and classic migraine (with aura or neurological symptoms). (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)

Research Excerpts

ExcerptRelevanceReference
"Migraine is a common cause of vertigo."5.32Treatment of migraine related vertigo with lamotrigine an observational study. ( Bisdorff, AR, 2004)
"Lamotrigine was most effective in trigeminal neuralgia and dysesthesia, but was of little utility in the other head or facial pains."3.80New generation anti-epileptics for facial pain and headache. ( Delvaux, V; Schoenen, J, 2001)
"Sixty patients with frequent migraine (more than 4 attacks per month) from the headache clinic at a tertiary referral centre in India were randomized to receive 50 mg topiramate/lamotrigine or matching placebo for 1 month each in 2 divided doses in 4 phases in a crossover manner with a washout period of 7 days in between."2.73Low-dose topiramate versus lamotrigine in migraine prophylaxis (the Lotolamp study). ( Behari, M; Goyal, V; Gupta, P; Shukla, G; Singh, S, 2007)
"Thirteen patients suffering from migraine with aura and 2 patients with aura but without migraine were enrolled and treated with lamotrigine."2.69Lamotrigine in the prophylactic treatment of migraine aura--a pilot study. ( Buzath, A; Klinger, D; Lampl, C; Neumann, K, 1999)
"We studied 24 patients affected by migraine with aura with a high frequency of attacks."2.69Effectiveness of lamotrigine in the prophylaxis of migraine with aura: an open pilot study. ( Cadaldini, M; D'Andrea, G; Granella, F; Manzoni, GC, 1999)
"The TACs include cluster headache, paroxysmal hemicrania, and short-lasting neuralgiform headache attacks with conjunctival injection and tearing; hemicrania continua, although classified separately by the International Headache Society, shares many features of both migraine and the TACs."2.49Primary headache disorders. ( Benoliel, R; Eliav, E, 2013)
"Topiramate was more likely prescribed for those with comorbid headache or migraine (incident: 335 of 1251 [26."1.51Antiepileptic Drug Treatment Patterns in Women of Childbearing Age With Epilepsy. ( Faught, E; Fishman, J; Kalilani, L; Kim, H; Thurman, DJ, 2019)
"Lamotrigine was the most frequently initiated drug in psychiatry, in both boys and girls."1.48Utilization of Antiepileptic Medicines in Swedish Children and Adolescents with Different Diagnoses. ( Karlsson Lind, L; von Euler, M; Wettermark, B; Wide, K, 2018)
"Background The impact of adverse events (AEs) of antiepileptic drugs (AEDs) have an impact on compliance and dropouts."1.48Antiepileptic drugs in migraine and epilepsy: Who is at increased risk of adverse events? ( Bedetti, C; Calabresi, P; Caproni, S; Corbelli, I; Costa, C; Cupini, LM; Eusebi, P; Romoli, M; Sarchielli, P; Siliquini, S, 2018)
"Because chronic treatment with migraine prophylactic drugs suppresses SD susceptibility, we tested whether migraine prophylaxis can also suppress ischemic depolarizations and improve stroke outcome."1.42Migraine prophylaxis, ischemic depolarizations, and stroke outcomes in mice. ( Ayata, C; Can, A; Daneshmand, A; Eikermann-Haerter, K; Ferrari, MD; Lee, JH; Sengul, B; van den Maagdenberg, AM; Wei, Y; Yalcin, N; Yu, ES; Zheng, Y, 2015)
"Lamotrigine has a marked suppressive effect which correlates with its rather selective action on the migraine aura."1.37Migraine preventive drugs differentially affect cortical spreading depression in rat. ( Bogdanov, VB; Bogdanova, OV; Chauvel, V; Makarchuk, MY; Multon, S; Prodanov, D; Schoenen, J, 2011)
"Migraine is a common cause of vertigo."1.32Treatment of migraine related vertigo with lamotrigine an observational study. ( Bisdorff, AR, 2004)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (31.25)18.2507
2000's3 (18.75)29.6817
2010's7 (43.75)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Groenke, BR1
Daline, IH1
Nixdorf, DR1
Karlsson Lind, L1
Wide, K1
Wettermark, B1
von Euler, M1
Kim, H1
Faught, E1
Thurman, DJ1
Fishman, J1
Kalilani, L1
Benoliel, R1
Eliav, E1
Eikermann-Haerter, K1
Lee, JH1
Yalcin, N1
Yu, ES1
Daneshmand, A1
Wei, Y1
Zheng, Y1
Can, A1
Sengul, B1
Ferrari, MD1
van den Maagdenberg, AM1
Ayata, C1
Romoli, M1
Costa, C1
Siliquini, S1
Corbelli, I1
Eusebi, P1
Bedetti, C1
Caproni, S1
Cupini, LM1
Calabresi, P1
Sarchielli, P1
Bogdanov, VB1
Multon, S1
Chauvel, V1
Bogdanova, OV1
Prodanov, D1
Makarchuk, MY1
Schoenen, J2
Ortiz, A1
Alda, M1
O'Donovan, C1
Bisdorff, AR1
Gupta, P1
Singh, S1
Goyal, V1
Shukla, G1
Behari, M1
Mathew, NT1
Steiner, TJ1
Findley, LJ1
Yuen, AW1
Nicolodi, M1
Del Bianco, PL1
Sicuteri, F1
Lampl, C1
Buzath, A1
Klinger, D1
Neumann, K1
D'Andrea, G1
Granella, F1
Cadaldini, M1
Manzoni, GC1
Delvaux, V1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Generating Evidence on NonEpileptic, Stereotypical and Intermittent Symptoms (NESIS) in Chronic Subdural Hematomas[NCT04759196]Phase 456 participants (Anticipated)Interventional2021-03-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for lamotrigine and Migraine Disorders

ArticleYear
Primary headache disorders.
    Dental clinics of North America, 2013, Volume: 57, Issue:3

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anticonvulsants; Chronic Disease; Cluster Headache; Cycloox

2013
New generation anti-epileptics for facial pain and headache.
    Acta neurologica Belgica, 2001, Volume: 101, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Facial Pain; Humans; Lamotrigine; Middle Aged; Migr

2001

Trials

5 trials available for lamotrigine and Migraine Disorders

ArticleYear
Low-dose topiramate versus lamotrigine in migraine prophylaxis (the Lotolamp study).
    Headache, 2007, Volume: 47, Issue:3

    Topics: Adolescent; Adult; Calcium Channel Blockers; Dose-Response Relationship, Drug; Drug Therapy, Combina

2007
Lamotrigine versus placebo in the prophylaxis of migraine with and without aura.
    Cephalalgia : an international journal of headache, 1997, Volume: 17, Issue:2

    Topics: Adolescent; Adult; Calcium Channel Blockers; Double-Blind Method; Female; Humans; Lamotrigine; Male;

1997
Lamotrigine in the prophylactic treatment of migraine aura--a pilot study.
    Cephalalgia : an international journal of headache, 1999, Volume: 19, Issue:1

    Topics: Adolescent; Adult; Excitatory Amino Acid Antagonists; Female; Humans; Lamotrigine; Male; Middle Aged

1999
Effectiveness of lamotrigine in the prophylaxis of migraine with aura: an open pilot study.
    Cephalalgia : an international journal of headache, 1999, Volume: 19, Issue:1

    Topics: Adolescent; Adult; Analgesics; Female; Humans; Lamotrigine; Male; Middle Aged; Migraine Disorders; P

1999
New generation anti-epileptics for facial pain and headache.
    Acta neurologica Belgica, 2001, Volume: 101, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Facial Pain; Humans; Lamotrigine; Middle Aged; Migr

2001

Other Studies

10 other studies available for lamotrigine and Migraine Disorders

ArticleYear
SUNCT/SUNA: Case series presenting in an orofacial pain clinic.
    Cephalalgia : an international journal of headache, 2021, Volume: 41, Issue:6

    Topics: Adult; Autonomic Nervous System Diseases; Facial Pain; Female; Gabapentin; Headache Disorders; Human

2021
Utilization of Antiepileptic Medicines in Swedish Children and Adolescents with Different Diagnoses.
    Basic & clinical pharmacology & toxicology, 2018, Volume: 123, Issue:1

    Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Drug Prescriptions; Drug Utilization; Epilepsy

2018
Antiepileptic Drug Treatment Patterns in Women of Childbearing Age With Epilepsy.
    JAMA neurology, 2019, 07-01, Volume: 76, Issue:7

    Topics: Adolescent; Adult; Anticonvulsants; Anxiety Disorders; Comorbidity; Dissociative Disorders; Epilepsi

2019
Migraine prophylaxis, ischemic depolarizations, and stroke outcomes in mice.
    Stroke, 2015, Volume: 46, Issue:1

    Topics: Animals; Anticonvulsants; Brain Ischemia; Calcium Channels, N-Type; Chemoprevention; Cortical Spread

2015
Antiepileptic drugs in migraine and epilepsy: Who is at increased risk of adverse events?
    Cephalalgia : an international journal of headache, 2018, Volume: 38, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Child; Epilepsy; Female; Humans; Lamotr

2018
Migraine preventive drugs differentially affect cortical spreading depression in rat.
    Neurobiology of disease, 2011, Volume: 41, Issue:2

    Topics: Animals; Anticonvulsants; Cortical Spreading Depression; Lamotrigine; Male; Migraine Disorders; Rats

2011
Tourette syndrome with comorbid bipolar disorder and migraine: can lamotrigine monotherapy help?
    Journal of clinical psychopharmacology, 2012, Volume: 32, Issue:1

    Topics: Adult; Bipolar Disorder; Brain; Comorbidity; Compulsive Behavior; Female; Follow-Up Studies; Halluci

2012
Treatment of migraine related vertigo with lamotrigine an observational study.
    Bulletin de la Societe des sciences medicales du Grand-Duche de Luxembourg, 2004, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Analgesics; Female; Headache; Humans; Lamotrigine; Male; Middle Aged

2004
Valproate and lamotrigine in migraine.
    Cephalalgia : an international journal of headache, 1997, Volume: 17, Issue:2

    Topics: Calcium Channel Blockers; Humans; Lamotrigine; Migraine Disorders; Triazines; Valproic Acid

1997
Modulation of excitatory amino acids pathway: a possible therapeutic approach to chronic daily headache associated with analgesic drugs abuse.
    International journal of clinical pharmacology research, 1997, Volume: 17, Issue:2-3

    Topics: Acetates; Adult; Amines; Chronic Disease; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagon

1997