Page last updated: 2024-10-30

lamotrigine and Long QT Syndrome

lamotrigine has been researched along with Long QT Syndrome in 2 studies

Long QT Syndrome: A condition that is characterized by episodes of fainting (SYNCOPE) and varying degree of ventricular arrhythmia as indicated by the prolonged QT interval. The inherited forms are caused by mutation of genes encoding cardiac ion channel proteins. The two major forms are ROMANO-WARD SYNDROME and JERVELL-LANGE NIELSEN SYNDROME.

Research Excerpts

ExcerptRelevanceReference
"Moxifloxacin was associated with a maximum mean increase from baseline in QTcF of 14."2.73Lamotrigine does not prolong QTc in a thorough QT/QTc study in healthy subjects. ( Dixon, R; Job, S; Lorch, U; Maltby, K; Oliver, R; Taubel, J; Tompson, D; Wright, JG, 2008)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dixon, R1
Job, S1
Oliver, R1
Tompson, D1
Wright, JG1
Maltby, K1
Lorch, U1
Taubel, J1
Aurlien, D1
Leren, TP1
Taubøll, E1
Gjerstad, L1

Trials

1 trial available for lamotrigine and Long QT Syndrome

ArticleYear
Lamotrigine does not prolong QTc in a thorough QT/QTc study in healthy subjects.
    British journal of clinical pharmacology, 2008, Volume: 66, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Anti-Arrhythmia Agents; Aza Compounds; Cross-Over Studies;

2008

Other Studies

1 other study available for lamotrigine and Long QT Syndrome

ArticleYear
New SCN5A mutation in a SUDEP victim with idiopathic epilepsy.
    Seizure, 2009, Volume: 18, Issue:2

    Topics: Adolescent; Anticonvulsants; Base Sequence; Death, Sudden, Cardiac; Epilepsy; Female; Humans; Lamotr

2009