lamotrigine has been researched along with Liver Failure, Acute in 9 studies
Liver Failure, Acute: A form of rapid-onset LIVER FAILURE, also known as fulminant hepatic failure, caused by severe liver injury or massive loss of HEPATOCYTES. It is characterized by sudden development of liver dysfunction and JAUNDICE. Acute liver failure may progress to exhibit cerebral dysfunction even HEPATIC COMA depending on the etiology that includes hepatic ISCHEMIA, drug toxicity, malignant infiltration, and viral hepatitis such as post-transfusion HEPATITIS B and HEPATITIS C.
| Excerpt | Relevance | Reference |
|---|---|---|
| "An 8-year-old boy with a known seizure disorder that was being treated with lamotrigine developed acute hepatic failure." | 7.70 | Acute hepatic failure in a child treated with lamotrigine. ( Arnon, R; Defelice, AR; DeVivo, D; Kazlow, PG, 1998) |
| " We describe a case of AHS with fulminant hepatitis that occurred two weeks after introduction of lamotrigine in a 40-year-old female patient with a recently diagnosed bipolar disorder, no pre-existent systemic organ involvement, and no other medication." | 4.85 | Fulminant hepatitis induced by lamotrigine. ( Marleau, D; Ouellet, G; Tremblay, L, 2009) |
| "An 8-year-old boy with a known seizure disorder that was being treated with lamotrigine developed acute hepatic failure." | 3.70 | Acute hepatic failure in a child treated with lamotrigine. ( Arnon, R; Defelice, AR; DeVivo, D; Kazlow, PG, 1998) |
| "Lamotrigine is a new antiepileptic drug that is effective for a broad range of seizures in adults and children." | 2.41 | Potential hepatotoxicity of lamotrigine. ( Choueiri, R; Fayad, M; Mikati, M, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 8 (88.89) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bushardt, RL | 1 |
| Ouellet, G | 1 |
| Tremblay, L | 1 |
| Marleau, D | 1 |
| Mecarelli, O | 1 |
| Pulitano, P | 1 |
| Mingoia, M | 1 |
| Ferretti, G | 1 |
| Rossi, M | 1 |
| Berloco, PB | 1 |
| Muda, AO | 1 |
| Shawcross, D | 2 |
| Knighton, S | 1 |
| Bernal, W | 1 |
| Sizer, E | 1 |
| Auzinger, G | 2 |
| Iniesta, I | 1 |
| Moeller, KE | 1 |
| Wei, L | 1 |
| Jewell, AD | 1 |
| Carver, LA | 1 |
| Arnon, R | 1 |
| DeVivo, D | 1 |
| Defelice, AR | 1 |
| Kazlow, PG | 1 |
| Fayad, M | 1 |
| Choueiri, R | 1 |
| Mikati, M | 1 |
2 reviews available for lamotrigine and Liver Failure, Acute
| Article | Year |
|---|---|
Fulminant hepatitis induced by lamotrigine.
Topics: Adult; Anticonvulsants; Bipolar Disorder; Chemical and Drug Induced Liver Injury; Female; Humans; La | 2009 |
Potential hepatotoxicity of lamotrigine.
Topics: Anticonvulsants; Child, Preschool; Encephalitis; Epilepsy; Humans; Lamotrigine; Liver Failure, Acute | 2000 |
7 other studies available for lamotrigine and Liver Failure, Acute
| Article | Year |
|---|---|
Anticonvulsant hypersensitivity syndrome and drug-induced hepatic injury.
Topics: Adult; Anticonvulsants; Chemical and Drug Induced Liver Injury; Drug Eruptions; Female; Humans; Lamo | 2009 |
Acute hepatitis associated with lamotrigine and managed with the molecular adsorbents recirculating system (Mars).
Topics: Adult; Anticonvulsants; Chemical and Drug Induced Liver Injury; Child; Electroencephalography; Epile | 2005 |
Old versus new antiepileptic drugs: the SANAD study.
Topics: Adult; Anticonvulsants; Epilepsy; Female; Humans; Lamotrigine; Liver Failure, Acute; Triazines | 2007 |
Lamotrigine and the risk of fulminant hepatic failure.
Topics: Anticonvulsants; Cytomegalovirus Infections; Female; Humans; Lamotrigine; Liver Failure, Acute; Risk | 2007 |
Lamotrigine and the risk of fulminant hepatic failure.
Topics: Anticonvulsants; Cytomegalovirus Infections; Female; Humans; Lamotrigine; Liver Failure, Acute; Risk | 2008 |
Acute hepatotoxicity associated with lamotrigine.
Topics: Adult; Anticonvulsants; Humans; Lamotrigine; Liver Failure, Acute; Male; Schizophrenia; Triazines | 2008 |
Acute hepatic failure in a child treated with lamotrigine.
Topics: Anticonvulsants; Child; Humans; Lamotrigine; Liver Failure, Acute; Male; Triazines | 1998 |