lamotrigine has been researched along with Kidney Failure, Chronic in 3 studies
Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A bipolar disorder patient stabilized on lamotrigine 200 mg total daily dose was admitted to the hospital with end-stage renal disease." | 7.76 | Lamotrigine and hemodialysis in bipolar disorder: case analysis of dosing strategy with literature review. ( Kaufman, KR, 2010) |
| "A bipolar disorder patient stabilized on lamotrigine 200 mg total daily dose was admitted to the hospital with end-stage renal disease." | 3.76 | Lamotrigine and hemodialysis in bipolar disorder: case analysis of dosing strategy with literature review. ( Kaufman, KR, 2010) |
| "For lamotrigine, there were no significant differences in Cmax, tmax, AUC, t1/2,z, CL/F and amount excreted in urine although t1/2,z tended to be longer for the renal failure group with a mean (+/-s." | 1.30 | Comparison of the pharmacokinetics of lamotrigine in patients with chronic renal failure and healthy volunteers. ( Cooper, JD; Posner, J; Rolan, PE; Sheung, CT; Soul-Lawton, J; Wootton, R, 1997) |
| " The elimination half-life of lamotrigine was approximately 25 h in subjects with normal renal function and 50 h in uraemic patients." | 1.29 | Pharmacokinetics of lamotrigine in patients with renal impairment: influence of haemodialysis. ( Bidault, R; Etienne, I; Fialaire, A; Fillastre, JP; Singlas, E; Taburet, AM, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kaufman, KR | 1 |
| Fillastre, JP | 1 |
| Taburet, AM | 1 |
| Fialaire, A | 1 |
| Etienne, I | 1 |
| Bidault, R | 1 |
| Singlas, E | 1 |
| Wootton, R | 1 |
| Soul-Lawton, J | 1 |
| Rolan, PE | 1 |
| Sheung, CT | 1 |
| Cooper, JD | 1 |
| Posner, J | 1 |
3 other studies available for lamotrigine and Kidney Failure, Chronic
| Article | Year |
|---|---|
Lamotrigine and hemodialysis in bipolar disorder: case analysis of dosing strategy with literature review.
Topics: Antimanic Agents; Bipolar Disorder; Drug Administration Schedule; Drug Monitoring; Humans; Kidney Fa | 2010 |
Pharmacokinetics of lamotrigine in patients with renal impairment: influence of haemodialysis.
Topics: Adult; Aged; Anticonvulsants; Chromatography, High Pressure Liquid; Female; Glucuronates; Half-Life; | 1993 |
Comparison of the pharmacokinetics of lamotrigine in patients with chronic renal failure and healthy volunteers.
Topics: Administration, Oral; Adult; Analysis of Variance; Anticonvulsants; Drug Monitoring; Female; Humans; | 1997 |