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lamotrigine and Inflammation

lamotrigine has been researched along with Inflammation in 7 studies

Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.

Research Excerpts

ExcerptRelevanceReference
"Intrathecal (IT) lamotrigine, a sodium channel blocker which suppresses neuronal release of glutamate, has been shown to produce a long-lasting antihyperalgesic effect in the neuropathic pain models."7.71The thermal and mechanical anti-hyperalgesic effects of pre- versus post-intrathecal treatment with lamotrigine in a rat model of inflammatory pain. ( Buerkle, H; Lee, TH; Lin, SH; Wang, CJ; Wu, PC; Yang, LC, 2002)
"Some opioid-resistant pain conditions can be alleviated by voltage-dependent Na(+) channel blockers such as lamotrigine."7.71Non-opioid actions of lamotrigine within the rat dorsal horn after inflammation and neuropathic nerve damage. ( Blackburn-Munro, G; Dickinson, T; Fleetwood-Walker, SM, 2001)
"Intrathecal (IT) lamotrigine, a sodium channel blocker which suppresses neuronal release of glutamate, has been shown to produce a long-lasting antihyperalgesic effect in the neuropathic pain models."3.71The thermal and mechanical anti-hyperalgesic effects of pre- versus post-intrathecal treatment with lamotrigine in a rat model of inflammatory pain. ( Buerkle, H; Lee, TH; Lin, SH; Wang, CJ; Wu, PC; Yang, LC, 2002)
"Some opioid-resistant pain conditions can be alleviated by voltage-dependent Na(+) channel blockers such as lamotrigine."3.71Non-opioid actions of lamotrigine within the rat dorsal horn after inflammation and neuropathic nerve damage. ( Blackburn-Munro, G; Dickinson, T; Fleetwood-Walker, SM, 2001)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (42.86)29.6817
2010's3 (42.86)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Jarvis, MF1
Honore, P1
Shieh, CC1
Chapman, M1
Joshi, S1
Zhang, XF1
Kort, M1
Carroll, W1
Marron, B1
Atkinson, R1
Thomas, J1
Liu, D1
Krambis, M1
Liu, Y1
McGaraughty, S1
Chu, K1
Roeloffs, R1
Zhong, C1
Mikusa, JP1
Hernandez, G1
Gauvin, D1
Wade, C1
Zhu, C1
Pai, M1
Scanio, M1
Shi, L1
Drizin, I1
Gregg, R1
Matulenko, M1
Hakeem, A1
Gross, M1
Johnson, M1
Marsh, K1
Wagoner, PK1
Sullivan, JP1
Faltynek, CR1
Krafte, DS1
Saunders, MJ1
Edwards, BS1
Zhu, J1
Sklar, LA1
Graves, SW1
Faustmann, TJ1
Corvace, F1
Faustmann, PM1
Ismail, FS1
Abu-Rish, EY1
Dahabiyeh, LA1
Bustanji, Y1
Mohamed, YS1
Browning, MJ1
Wang, K1
Fernandez-Escobar, A1
Han, S1
Zhu, P1
Wang, JH1
Sun, Y1
Lee, TH1
Wang, CJ1
Wu, PC1
Buerkle, H1
Lin, SH1
Yang, LC1
Blackburn-Munro, G1
Dickinson, T1
Fleetwood-Walker, SM1

Other Studies

7 other studies available for lamotrigine and Inflammation

ArticleYear
A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, May-15, Volume: 104, Issue:20

    Topics: Action Potentials; Analgesics; Aniline Compounds; Animals; Capsaicin; Evoked Potentials; Furans; Gan

2007
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
    Current protocols in cytometry, 2010, Volume: Chapter 13

    Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr

2010
Effects of Lamotrigine and Topiramate on Glial Properties in an Astrocyte-Microglia Co-Culture Model of Inflammation.
    The international journal of neuropsychopharmacology, 2022, 03-17, Volume: 25, Issue:3

    Topics: Animals; Anticonvulsants; Astrocytes; Coculture Techniques; Connexin 43; Cytokines; Epilepsy; Inflam

2022
Effect of lamotrigine on in vivo and in vitro cytokine secretion in murine model of inflammation.
    Journal of neuroimmunology, 2018, 09-15, Volume: 322

    Topics: Animals; Anticonvulsants; Concanavalin A; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosor

2018
Lamotrigine Reduces Inflammatory Response and Ameliorates Executive Function Deterioration in an Alzheimer's-Like Mouse Model.
    BioMed research international, 2016, Volume: 2016

    Topics: Alzheimer Disease; Animals; Brain; Cognition Disorders; Cytokines; Disease Models, Animal; Gene Expr

2016
The thermal and mechanical anti-hyperalgesic effects of pre- versus post-intrathecal treatment with lamotrigine in a rat model of inflammatory pain.
    Life sciences, 2002, May-10, Volume: 70, Issue:25

    Topics: Analgesics; Animals; Arthritis, Experimental; Dose-Response Relationship, Drug; Inflammation; Inject

2002
Non-opioid actions of lamotrigine within the rat dorsal horn after inflammation and neuropathic nerve damage.
    Neuroscience research, 2001, Volume: 39, Issue:4

    Topics: Action Potentials; Analgesics, Opioid; Animals; Anti-Anxiety Agents; Calcium Channel Blockers; Chole

2001