lamotrigine has been researched along with Epilepsies, Myoclonic in 27 studies
Epilepsies, Myoclonic: A clinically diverse group of epilepsy syndromes characterized either by myoclonic seizures or by myoclonus in association with other seizure types. Myoclonic epilepsy syndromes are divided into three subtypes based on etiology: familial, cryptogenic, and symptomatic.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Herein, we describe two young men with epilepsy who experienced severe loss of libido and anhedonia after levetiracetam intake." | 7.78 | Levetiracetam-associated loss of libido and anhedonia. ( Bramanti, P; Calabrò, RS; Italiano, D; Militi, D, 2012) |
| "An 8-year-old girl with Lennox-Gastaut syndrome showed a partial reduction in seizure frequency when lamotrigine (LTG), 15 mg/kg per day, was added to clobazam (CLB) and vigabatrin (VGB)." | 7.70 | Myoclonic status epilepticus following high-dosage lamotrigine therapy. ( Belmonte, A; Guerrini, R; Parmeggiani, L; Perucca, E, 1999) |
| "We investigated the effect of pregnancy on the kinetics of lamotrigine (LTG), passage of LTG over the placenta and the excretion of the drug in breast milk." | 7.69 | Lamotrigine in pregnancy and lactation: a case report. ( Ohman, I; Tomson, T; Vitols, S, 1997) |
| " Lamotrigine (LTG), an AED that is effective for both focal and generalized seizures, has been reported to aggravate seizures in Dravet syndrome." | 3.81 | Lamotrigine can be beneficial in patients with Dravet syndrome. ( Dalic, L; Mullen, SA; Roulet Perez, E; Scheffer, I, 2015) |
| " Herein, we describe two young men with epilepsy who experienced severe loss of libido and anhedonia after levetiracetam intake." | 3.78 | Levetiracetam-associated loss of libido and anhedonia. ( Bramanti, P; Calabrò, RS; Italiano, D; Militi, D, 2012) |
| "Five patients with idiopathic generalized epilepsies (IGE) treated with lamotrigine (LTG) experienced exacerbation or de novo appearance of myoclonic jerks (MJ)." | 3.73 | Lamotrigine associated with exacerbation or de novo myoclonus in idiopathic generalized epilepsies. ( Baldy-Moulinier, M; Berramdane, M; Coubes, P; Crespel, A; Gelisse, P; Genton, P; Monicard, C, 2005) |
| "An 8-year-old girl with Lennox-Gastaut syndrome showed a partial reduction in seizure frequency when lamotrigine (LTG), 15 mg/kg per day, was added to clobazam (CLB) and vigabatrin (VGB)." | 3.70 | Myoclonic status epilepticus following high-dosage lamotrigine therapy. ( Belmonte, A; Guerrini, R; Parmeggiani, L; Perucca, E, 1999) |
| "We investigated the effect of pregnancy on the kinetics of lamotrigine (LTG), passage of LTG over the placenta and the excretion of the drug in breast milk." | 3.69 | Lamotrigine in pregnancy and lactation: a case report. ( Ohman, I; Tomson, T; Vitols, S, 1997) |
| "Lamotrigine was introduced and titrated using a schedule based on the patients' age and concurrent antiepileptic drug regimen." | 2.72 | Lamotrigine adjunctive therapy among children and adolescents with primary generalized tonic-clonic seizures. ( Hammer, AE; Kerls, SP; Messenheimer, JA; Trevathan, E; Vuong, A, 2006) |
| "Vigabatrin has shown promise in treating IS patients, particularly those with tuberous sclerosis." | 2.42 | Pharmacologic treatment of the catastrophic epilepsies. ( Conry, JA, 2004) |
| "Severe myoclonic epilepsy of infants usually worsens with lamotrigine, but occasionally, children improve." | 2.40 | Myoclonus and epilepsy in childhood: a review of treatment with valproate, ethosuximide, lamotrigine and zonisamide. ( Wallace, SJ, 1998) |
| "Epilepsy was diagnosed in 54." | 1.62 | The molecular and phenotypic spectrum of CLCN4-related epilepsy. ( Cao, D; Fahlke, C; Guzman, RE; He, H; Peng, J; Sierra-Marquez, J; Stauber, T; Yin, F, 2021) |
| "Response to AED and change in seizure frequency/pattern on follow-up were noted." | 1.43 | Epilepsy with myoclonic absences: Electroclinical characteristics in a distinctive pediatric epilepsy phenotype. ( Jagtap, S; Karkare, K; Menon, RN; Radhakrishnan, A; Soni, H; Zanzmera, P, 2016) |
| " A significant relationship between seizure frequency per day and LTG dosage during titration and follow-up phase could be demonstrated in nine patients." | 1.39 | Myoclonic astatic epilepsy (Doose syndrome) - a lamotrigine responsive epilepsy? ( Boor, R; Doege, C; May, TW; Siniatchkin, M; Stephani, U; von Spiczak, S, 2013) |
| "Lamotrigine was stopped and progressively the drops of the legs disappeared within 6 months but valproate was continued." | 1.38 | Worsening of negative myoclonus by lamotrigine in a case of idiopathic focal epilepsy of children with long-term follow-up. ( Crespel, A; Gélisse, P; Genton, P; Serafini, A; Velizarova, R, 2012) |
| "In severe myoclonic epilepsy of infancy (SME), multiple drug-resistant focal and generalized seizure types occur." | 1.30 | Lamotrigine and seizure aggravation in severe myoclonic epilepsy. ( Belmonte, A; Dravet, C; Dulac, O; Genton, P; Guerrini, R; Kaminska, A, 1998) |
| "Lamotrigine was effective and well tolerated in patients with various IGE syndromes, although differences were observed between individual syndromes and seizure types." | 1.30 | Efficacy of lamotrigine in idiopathic generalized epilepsy syndromes: a video-EEG-controlled, open study. ( de Saint-Martin, A; Gericke, CA; Hirsch, E; Marescaux, C; Picard, F; Strumia, S, 1999) |
| "Juvenile myoclonic epilepsy is a relatively common, though under diagnosed, form of epilepsy that commences in adolescence." | 1.29 | Juvenile myoclonic epilepsy. ( Buchanan, N, 1995) |
| "Juvenile myoclonic epilepsy is a common, under-recognised form of epilepsy which is best treated with sodium valproate." | 1.29 | Juvenile myoclonic epilepsy: diagnosis, management and outcome. ( Buchanan, N; Sharpe, C, 1995) |
| "Lamotrigine is a useful alternative in the management of JME." | 1.29 | The use of lamotrigine in juvenile myoclonic epilepsy. ( Buchanan, N, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (40.74) | 18.2507 |
| 2000's | 8 (29.63) | 29.6817 |
| 2010's | 7 (25.93) | 24.3611 |
| 2020's | 1 (3.70) | 2.80 |
| Authors | Studies |
|---|---|
| He, H | 1 |
| Guzman, RE | 1 |
| Cao, D | 1 |
| Sierra-Marquez, J | 1 |
| Yin, F | 1 |
| Fahlke, C | 1 |
| Peng, J | 1 |
| Stauber, T | 1 |
| Dalic, L | 1 |
| Mullen, SA | 1 |
| Roulet Perez, E | 1 |
| Scheffer, I | 1 |
| Andrade, DM | 1 |
| Zanzmera, P | 1 |
| Menon, RN | 1 |
| Karkare, K | 1 |
| Soni, H | 1 |
| Jagtap, S | 1 |
| Radhakrishnan, A | 1 |
| Gélisse, P | 2 |
| Genton, P | 3 |
| Velizarova, R | 1 |
| Serafini, A | 1 |
| Crespel, A | 2 |
| Calabrò, RS | 1 |
| Italiano, D | 1 |
| Militi, D | 1 |
| Bramanti, P | 1 |
| Thompson, CH | 1 |
| Porter, JC | 1 |
| Kahlig, KM | 1 |
| Daniels, MA | 1 |
| George, AL | 1 |
| Doege, C | 1 |
| May, TW | 1 |
| Siniatchkin, M | 1 |
| von Spiczak, S | 1 |
| Stephani, U | 1 |
| Boor, R | 1 |
| Conry, JA | 1 |
| Burneo, JG | 1 |
| Miller, S | 1 |
| Bebin, EM | 1 |
| Prasad, A | 1 |
| Gentile, S | 1 |
| Berramdane, M | 1 |
| Coubes, P | 1 |
| Monicard, C | 1 |
| Baldy-Moulinier, M | 1 |
| Trevathan, E | 1 |
| Kerls, SP | 1 |
| Hammer, AE | 1 |
| Vuong, A | 1 |
| Messenheimer, JA | 1 |
| Zesiewicz, TA | 1 |
| Sullivan, KL | 1 |
| Hauser, RA | 1 |
| Piantino, JA | 1 |
| Torres, A | 1 |
| Kilaru, S | 1 |
| Bergqvist, AGC | 1 |
| Buchanan, N | 3 |
| Sharpe, C | 1 |
| Ferrie, CD | 1 |
| Panayiotopoulos, CP | 1 |
| Fogh, K | 1 |
| Mai, J | 1 |
| Wallace, SJ | 1 |
| Tomson, T | 1 |
| Ohman, I | 1 |
| Vitols, S | 1 |
| Guerrini, R | 2 |
| Dravet, C | 1 |
| Belmonte, A | 2 |
| Kaminska, A | 1 |
| Dulac, O | 1 |
| Parmeggiani, L | 1 |
| Perucca, E | 1 |
| Mecarelli, O | 1 |
| de Feo, MR | 1 |
| Accornero, N | 1 |
| Paffetti, A | 1 |
| Gericke, CA | 1 |
| Picard, F | 1 |
| de Saint-Martin, A | 1 |
| Strumia, S | 1 |
| Marescaux, C | 1 |
| Hirsch, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The BrainDrugs-Epilepsy Study: A Prospective Open-label Cohort Precision Medicine Study in Epilepsy[NCT05450822] | 550 participants (Anticipated) | Observational | 2022-02-18 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for lamotrigine and Epilepsies, Myoclonic
| Article | Year |
|---|---|
Pharmacologic treatment of the catastrophic epilepsies.
Topics: Anticonvulsants; Child, Preschool; Epilepsies, Myoclonic; Epilepsy; Fructose; Humans; Infant; Isoxaz | 2004 |
Myoclonus and epilepsy in childhood: a review of treatment with valproate, ethosuximide, lamotrigine and zonisamide.
Topics: Anticonvulsants; Child; Child, Preschool; Epilepsies, Myoclonic; Ethosuximide; Humans; Infant; Isoxa | 1998 |
1 trial available for lamotrigine and Epilepsies, Myoclonic
| Article | Year |
|---|---|
Lamotrigine adjunctive therapy among children and adolescents with primary generalized tonic-clonic seizures.
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Double-Blind Method; Drug Administratio | 2006 |
24 other studies available for lamotrigine and Epilepsies, Myoclonic
| Article | Year |
|---|---|
The molecular and phenotypic spectrum of CLCN4-related epilepsy.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Child; Child Behavior Disorders; Child, Preschool; Chlorid | 2021 |
Lamotrigine can be beneficial in patients with Dravet syndrome.
Topics: Adolescent; Adult; Anticonvulsants; Epilepsies, Myoclonic; Humans; Lamotrigine; Male; Seizures; Tria | 2015 |
Dravet syndrome, lamotrigine, and personalized medicine.
Topics: Anticonvulsants; Epilepsies, Myoclonic; Humans; Lamotrigine; Male; Triazines | 2015 |
Epilepsy with myoclonic absences: Electroclinical characteristics in a distinctive pediatric epilepsy phenotype.
Topics: Anticonvulsants; Brain; Child; Child, Preschool; Cohort Studies; Drug Therapy, Combination; Electroe | 2016 |
Worsening of negative myoclonus by lamotrigine in a case of idiopathic focal epilepsy of children with long-term follow-up.
Topics: Anticonvulsants; Child, Preschool; Drug Therapy, Combination; Electroencephalography; Epilepsies, My | 2012 |
Levetiracetam-associated loss of libido and anhedonia.
Topics: Adult; Anhedonia; Anticonvulsants; Brain; Electroencephalography; Epilepsies, Myoclonic; Epilepsy, C | 2012 |
Nontruncating SCN1A mutations associated with severe myoclonic epilepsy of infancy impair cell surface expression.
Topics: Alleles; Amino Acid Sequence; Amino Acid Substitution; Anticonvulsants; Cell Membrane; Epilepsies, M | 2012 |
Myoclonic astatic epilepsy (Doose syndrome) - a lamotrigine responsive epilepsy?
Topics: Anticonvulsants; Child; Child, Preschool; Epilepsies, Myoclonic; Female; Humans; Lamotrigine; Male; | 2013 |
Video-EEG study in an adult and a child with eyelid myoclonia with absences.
Topics: Adult; Anticonvulsants; Child; Dominance, Cerebral; Drug Therapy, Combination; Electroencephalograph | 2004 |
Lamotrigine in pregnancy and lactation.
Topics: Adult; Anticonvulsants; Epilepsies, Myoclonic; Female; Folic Acid; Humans; Infant, Newborn; Lactatio | 2005 |
Lamotrigine associated with exacerbation or de novo myoclonus in idiopathic generalized epilepsies.
Topics: Adult; Anticonvulsants; Brain; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Epilepsie | 2005 |
Chorea induced by lamotrigine.
Topics: Anticonvulsants; Child; Child Behavior Disorders; Chorea; Electroencephalography; Epilepsies, Myoclo | 2006 |
Myoclonic seizures in a patient with Charcot-Marie-tooth disease.
Topics: Anticonvulsants; Carbamazepine; Charcot-Marie-Tooth Disease; Child; Developmental Disabilities; Drug | 2007 |
Current treatment of myoclonic astatic epilepsy: clinical experience at the Children's Hospital of Philadelphia.
Topics: Age of Onset; Anticonvulsants; Child; Cognition Disorders; Dietary Fats; Electroencephalography; Epi | 2007 |
Juvenile myoclonic epilepsy.
Topics: Adolescent; Age of Onset; Animals; Anticonvulsants; Child; Circadian Rhythm; Clonazepam; Cricetinae; | 1995 |
Juvenile myoclonic epilepsy: diagnosis, management and outcome.
Topics: Adolescent; Adult; Alcohol Drinking; Anticonvulsants; Carbamazepine; Epilepsies, Myoclonic; Female; | 1995 |
Therapeutic interaction of lamotrigine and sodium valproate in intractable myoclonic epilepsy.
Topics: Adolescent; Anticonvulsants; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combina | 1994 |
The use of lamotrigine in juvenile myoclonic epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Epilepsies, Myoclonic; Female; Humans; Lamotrigine; Triazines; V | 1996 |
Toxic epidermal necrolysis after treatment with lamotrigine (Lamictal).
Topics: Adult; Anticonvulsants; Biopsy; Dose-Response Relationship, Drug; Electroencephalography; Epilepsies | 1997 |
Lamotrigine in pregnancy and lactation: a case report.
Topics: Adult; Anticonvulsants; Breast Feeding; Chromatography, High Pressure Liquid; Dose-Response Relation | 1997 |
Lamotrigine and seizure aggravation in severe myoclonic epilepsy.
Topics: Acute Disease; Adolescent; Adult; Anticonvulsants; Child; Comorbidity; Drug Therapy, Combination; Ep | 1998 |
Myoclonic status epilepticus following high-dosage lamotrigine therapy.
Topics: Anticonvulsants; Child; Electroencephalography; Epilepsies, Myoclonic; Epilepsy, Absence; Female; Hu | 1999 |
Systemic lupus erythematosus and myoclonic epileptic manifestations.
Topics: Anti-Inflammatory Agents; Anticonvulsants; Child; Electroencephalography; Epilepsies, Myoclonic; Fem | 1999 |
Efficacy of lamotrigine in idiopathic generalized epilepsy syndromes: a video-EEG-controlled, open study.
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug | 1999 |