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lamotrigine and Dystonia

lamotrigine has been researched along with Dystonia in 4 studies

Dystonia: An attitude or posture due to the co-contraction of agonists and antagonist muscles in one region of the body. It most often affects the large axial muscles of the trunk and limb girdles. Conditions which feature persistent or recurrent episodes of dystonia as a primary manifestation of disease are referred to as DYSTONIC DISORDERS. (Adams et al., Principles of Neurology, 6th ed, p77)

Research Excerpts

ExcerptRelevanceReference
"Recent findings of antidystonic effects of NMDA and non-NMDA receptor antagonists in an inbred line of Syrian hamsters with primary generalized dystonia prompted us to investigate the effects of lamotrigine, an inhibitor of veratrine-induced glutamate release, on the severity of dystonia in mutant hamsters."7.69The novel antiepileptic drug, lamotrigine, exerts prodystonic effects in a mutant hamster model of generalized dystonia. ( Löscher, W; Löschmann, PA; Richter, A, 1994)
"The effects of riluzole (2-amino-6-trifluoromethoxy benzothiazole) on the severity of dystonia were examined in mutant hamsters (dtsz), an animal model of idiopathic dystonia in which dystonic attacks can be age dependently induced by mild stress."7.69Prodystonic effects of riluzole in an animal model of idiopathic dystonia related to decreased total power in the red nucleus? ( Gernert, M; Löscher, W; Richter, A, 1997)
"Recent findings of antidystonic effects of NMDA and non-NMDA receptor antagonists in an inbred line of Syrian hamsters with primary generalized dystonia prompted us to investigate the effects of lamotrigine, an inhibitor of veratrine-induced glutamate release, on the severity of dystonia in mutant hamsters."3.69The novel antiepileptic drug, lamotrigine, exerts prodystonic effects in a mutant hamster model of generalized dystonia. ( Löscher, W; Löschmann, PA; Richter, A, 1994)
"The effects of riluzole (2-amino-6-trifluoromethoxy benzothiazole) on the severity of dystonia were examined in mutant hamsters (dtsz), an animal model of idiopathic dystonia in which dystonic attacks can be age dependently induced by mild stress."3.69Prodystonic effects of riluzole in an animal model of idiopathic dystonia related to decreased total power in the red nucleus? ( Gernert, M; Löscher, W; Richter, A, 1997)
" The initial dosage of lamotrigine was 6."1.43Lamotrigine monotherapy for paroxysmal kinesigenic dyskinesia in children. ( Hu, Y; Li, F; Li, W; Lin, ZD; Poonit, ND; Xue, CC, 2016)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Marrero-Gonzalez, PC1
Ruano, OL1
Catalano, G1
Catalano, MC1
Li, F1
Lin, ZD1
Hu, Y1
Li, W1
Xue, CC1
Poonit, ND1
Richter, A2
Löschmann, PA1
Löscher, W2
Gernert, M1

Other Studies

4 other studies available for lamotrigine and Dystonia

ArticleYear
Dystonia associated with lamotrigine therapy: a case report and review of the literature.
    Current drug safety, 2014, Volume: 9, Issue:1

    Topics: Antidepressive Agents; Basal Ganglia Diseases; Dystonia; Humans; Lamotrigine; Male; Middle Aged; Moo

2014
Lamotrigine monotherapy for paroxysmal kinesigenic dyskinesia in children.
    Seizure, 2016, Volume: 37

    Topics: Anticonvulsants; Child; Child, Preschool; Dystonia; Electroencephalography; Epilepsy, Absence; Femal

2016
The novel antiepileptic drug, lamotrigine, exerts prodystonic effects in a mutant hamster model of generalized dystonia.
    European journal of pharmacology, 1994, Nov-03, Volume: 264, Issue:3

    Topics: Administration, Oral; Aging; Animals; Anticonvulsants; Cricetinae; Disease Models, Animal; Dose-Resp

1994
Prodystonic effects of riluzole in an animal model of idiopathic dystonia related to decreased total power in the red nucleus?
    European journal of pharmacology, 1997, Aug-06, Volume: 332, Issue:2

    Topics: Animals; Antiparkinson Agents; Calcium Channel Blockers; Cricetinae; Disease Models, Animal; Dystoni

1997