lamotrigine has been researched along with Drug Overdose in 34 studies
Drug Overdose: Accidental or deliberate use of a medication or street drug in excess of normal dosage.
Excerpt | Relevance | Reference |
---|---|---|
"Lamotrigine is a commonly prescribed anticonvulsant medication." | 5.34 | Seizures and altered mental status after lamotrigine overdose. ( Geller, RJ; Schwartz, MD, 2007) |
"Clinically significant side effects of the new anticonvulsants, such as metabolic acidosis from topiramate, autoimmune reactions from lamotrigine, hyponatremia from oxcarbazepine, or psychosis from levitiracetam can cause serious morbidity and mortality if unrecognized." | 4.86 | Emergent complications of the newer anticonvulsants. ( Dang, CV; Nelson, L; Wade, JF; Wasserberger, J, 2010) |
"Lamotrigine is a broad-spectrum anticonvulsant commonly used to treat seizure and bipolar mood disorders." | 2.58 | Acute lamotrigine overdose: a systematic review of published adult and pediatric cases. ( Alyahya, B; Friesen, M; Laliberté, M; Nauche, B, 2018) |
"The lamotrigine level was 78." | 2.52 | Evolving Electrocardiographic Changes in Lamotrigine Overdose: A Case Report and Literature Review. ( Casso Dominguez, A; Chavez, P; Herzog, E, 2015) |
"Epilepsy affects 1." | 2.41 | New antiepileptic drugs and preparations. ( Jagoda, A; Yoon, Y, 2000) |
"Lamotrigine is a phenyltriazine compound that inhibits voltage-gated sodium channels, decreasing release of glutamate and aspartate, and inhibits serotonin, norepinephrine and dopamine reuptake." | 1.39 | A case series of patients with lamotrigine toxicity at one center from 2003 to 2012. ( Burkhart, KK; Donovan, JW; Haggerty, D; Moore, PW, 2013) |
"Lamotrigine is a sodium channel blocking agent that is widely prescribed for treatment of seizure." | 1.38 | Lipid emulsion as rescue therapy in lamotrigine overdose. ( Castanares-Zapatero, D; Hantson, P; Huberlant, V; Morunglav, M; Wittebole, X, 2012) |
"We report a case of cardiac arrest and status epilepticus following a massive LTG overdose." | 1.37 | Severe sodium channel blockade and cardiovascular collapse due to a massive lamotrigine overdose. ( Ly, BT; Minns, AB; Nogar, JN; Savaser, DJ, 2011) |
"Lamotrigine is a phenyltriazine derivative used as antiepileptic drug with pharmacological profile similar to phenytoin." | 1.37 | [Massive lamotrigine poisoning--case report]. ( Bazylewicz, A; Kicka, M; Kłopotowski, T; Miśkiewicz, Ł; Picheta, S, 2011) |
"The patient presented with seizures and a reduced level of consciousness." | 1.34 | Self-poisoning with lamotrigine and pregabalin. ( Braga, AJ; Chidley, K, 2007) |
"Lamotrigine is a commonly prescribed anticonvulsant medication." | 1.34 | Seizures and altered mental status after lamotrigine overdose. ( Geller, RJ; Schwartz, MD, 2007) |
"Lamotrigine is a novel anticonvulsant initially used in epilepsy treatment." | 1.33 | The relevance of monitoring lamotrigine serum concentrations in chronic pain patients. ( Devulder, J, 2006) |
"Lamotrigine is an antiepileptic drug for the treatment of partial and generalized seizures as well as bipolar disorder." | 1.32 | Evaluation of lamotrigine toxicity reported to poison centers. ( Klein-Schwartz, W; Lofton, AL, 2004) |
"Lamotrigine (Lamictal) is a new anticonvulsant drug recently approved for use in the United States." | 1.31 | Lamotrigine distribution in two postmortem cases. ( Jufer, RA; Levine, B; Smialek, JE, 2000) |
"Lamotrigine is an antiepileptic agent that has been shown to be an effective adjunctive treatment for refractory partial and generalized seizures." | 1.31 | Lamotrigine overdose in an adult. ( Bateman, DN; O'Donnell, J, 2000) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 2 (5.88) | 18.2507 |
2000's | 14 (41.18) | 29.6817 |
2010's | 17 (50.00) | 24.3611 |
2020's | 1 (2.94) | 2.80 |
Authors | Studies |
---|---|
Gosselin, S | 1 |
Ghannoum, M | 1 |
Hoffman, RS | 1 |
Alyahya, B | 1 |
Friesen, M | 1 |
Nauche, B | 1 |
Laliberté, M | 1 |
Agrawal, A | 1 |
Nogar, JN | 2 |
Koenig, S | 1 |
Moore, PW | 1 |
Donovan, JW | 1 |
Burkhart, KK | 1 |
Haggerty, D | 1 |
Eren Cevik, S | 1 |
Tasyurek, T | 1 |
Guneysel, O | 1 |
Chavez, P | 1 |
Casso Dominguez, A | 1 |
Herzog, E | 1 |
Fettiplace, MR | 1 |
Akpa, BS | 1 |
Rubinstein, I | 1 |
Weinberg, G | 1 |
Grosso, S | 1 |
Ferranti, S | 1 |
Gaggiano, C | 1 |
Grande, E | 1 |
Loi, B | 1 |
Di Bartolo, R | 1 |
Tessitore, E | 1 |
Ramlawi, M | 1 |
Tobler, O | 1 |
Sunthorn, H | 1 |
Wade, JF | 1 |
Dang, CV | 1 |
Nelson, L | 1 |
Wasserberger, J | 1 |
Nixon, AC | 1 |
Doak, MW | 1 |
Crozier, H | 1 |
Crooks, DP | 1 |
Waring, WS | 1 |
Nwogbe, B | 1 |
Ferié, J | 1 |
Smith, H | 1 |
Gunawardena, I | 1 |
Dhatariya, K | 1 |
Veerapandiyan, A | 1 |
Gallentine, WB | 1 |
Winchester, SA | 1 |
Baker, J | 1 |
Kansagra, SM | 1 |
Mikati, MA | 1 |
French, LK | 1 |
McKeown, NJ | 1 |
Hendrickson, RG | 1 |
Castanares-Zapatero, D | 1 |
Wittebole, X | 1 |
Huberlant, V | 1 |
Morunglav, M | 1 |
Hantson, P | 1 |
Waldo, SW | 1 |
Treit, K | 1 |
Goldschlager, N | 1 |
Minns, AB | 1 |
Savaser, DJ | 1 |
Ly, BT | 1 |
Kicka, M | 1 |
Kłopotowski, T | 1 |
Picheta, S | 1 |
Bazylewicz, A | 1 |
Miśkiewicz, Ł | 1 |
Fleurat, M | 1 |
Smollin, C | 1 |
Devresse, A | 1 |
Maldague, P | 1 |
Coulier, B | 1 |
Pierard, F | 1 |
Gielen, I | 1 |
Lofton, AL | 1 |
Klein-Schwartz, W | 1 |
Devulder, J | 1 |
Braga, AJ | 1 |
Chidley, K | 1 |
Daana, M | 1 |
Nevo, Y | 1 |
Tenenbaum, A | 1 |
Taustein, I | 1 |
Berger, I | 1 |
Reimers, A | 1 |
Reinholt, G | 1 |
Schwartz, MD | 1 |
Geller, RJ | 1 |
Miller, MA | 1 |
Levsky, ME | 1 |
Stopforth, J | 1 |
Briassoulis, G | 1 |
Kalabalikis, P | 1 |
Tamiolaki, M | 1 |
Hatzis, T | 1 |
Levine, B | 1 |
Jufer, RA | 1 |
Smialek, JE | 1 |
Yoon, Y | 1 |
Jagoda, A | 1 |
O'Donnell, J | 1 |
Bateman, DN | 1 |
Mycyk, MB | 1 |
Carlson, A | 1 |
Sbei, M | 1 |
Campellone, JV | 1 |
4 reviews available for lamotrigine and Drug Overdose
Article | Year |
---|---|
Acute lamotrigine overdose: a systematic review of published adult and pediatric cases.
Topics: Adult; Anticonvulsants; Child; Drug Overdose; Humans; Lamotrigine; Renal Dialysis | 2018 |
Evolving Electrocardiographic Changes in Lamotrigine Overdose: A Case Report and Literature Review.
Topics: Adult; Antimanic Agents; Arrhythmias, Cardiac; Bipolar Disorder; Drug Overdose; Electrocardiography; | 2015 |
Emergent complications of the newer anticonvulsants.
Topics: Acidosis; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Overdose; Fructo | 2010 |
New antiepileptic drugs and preparations.
Topics: Acetates; Administration, Rectal; Age Factors; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; | 2000 |
30 other studies available for lamotrigine and Drug Overdose
Article | Year |
---|---|
Hemodialysis for lamotrigine poisoning.
Topics: Drug Overdose; Drug-Related Side Effects and Adverse Reactions; Humans; Lamotrigine; Renal Dialysis | 2020 |
Management of lamotrigine overdose using hemodialysis.
Topics: Adult; Anticonvulsants; Bipolar Disorder; Drug Overdose; Female; Humans; Lamotrigine; Renal Dialysis | 2019 |
A case series of patients with lamotrigine toxicity at one center from 2003 to 2012.
Topics: Adrenergic Uptake Inhibitors; Adult; Arrhythmias, Cardiac; Child, Preschool; Dopamine Uptake Inhibit | 2013 |
Intralipid emulsion treatment as an antidote in lipophilic drug intoxications.
Topics: Adolescent; Adult; Alprazolam; Amitriptyline; Antidotes; Blood Pressure; Dibenzothiazepines; Drug Ov | 2014 |
Confusion About Infusion: Rational Volume Limits for Intravenous Lipid Emulsion During Treatment of Oral Overdoses.
Topics: Bupropion; Drug Overdose; Fat Emulsions, Intravenous; Humans; Lamotrigine; Triazines | 2015 |
Massive lamotrigine poisoning. A case report.
Topics: Anticonvulsants; Child, Preschool; Diagnosis, Differential; Drug Overdose; Dyskinesia, Drug-Induced; | 2017 |
Brugada Pattern Caused by a Flecainide Overdose.
Topics: Atrial Fibrillation; Bipolar Disorder; Brugada Syndrome; Consciousness Disorders; Drug Overdose; Ele | 2017 |
Patterns of antiepileptic drug overdose differ between men and women: admissions to the Edinburgh Poisons Unit, 2000-2007.
Topics: Adult; Anticonvulsants; Carbamazepine; Drug Overdose; Female; Humans; Lamotrigine; Male; Middle Aged | 2009 |
Significant lamotrigine overdose associated with acute pancreatitis.
Topics: Acute Disease; Antidepressive Agents; Drug Overdose; Female; Humans; Lamotrigine; Pancreatitis; Tria | 2009 |
Oculogyric crises secondary to lamotrigine overdosage.
Topics: Adult; Anticonvulsants; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Overdose; Dr | 2011 |
Complete heart block and death following lamotrigine overdose.
Topics: Adult; Anticonvulsants; Drug Overdose; Fatal Outcome; Heart Block; Humans; Lamotrigine; Male; Renal | 2011 |
Lipid emulsion as rescue therapy in lamotrigine overdose.
Topics: Calcium Channel Blockers; Drug Overdose; Fat Emulsions, Intravenous; Female; Humans; Lamotrigine; Mi | 2012 |
Possible acute myocardial infarction in a hypothermic patient.
Topics: Acute Disease; Anticonvulsants; Antimanic Agents; Benzodiazepines; Bipolar Disorder; Drug Overdose; | 2011 |
Severe sodium channel blockade and cardiovascular collapse due to a massive lamotrigine overdose.
Topics: Calcium Channel Blockers; Drug Overdose; Female; Heart Arrest; Humans; Lamotrigine; Middle Aged; Sta | 2011 |
[Massive lamotrigine poisoning--case report].
Topics: Adult; Anticonvulsants; Coma; Drug Overdose; Epilepsy; Female; Humans; Lamotrigine; Respiratory Insu | 2011 |
Case files of the University of California San Francisco Medical Toxicology Fellowship: lamotrigine toxicity.
Topics: Anticonvulsants; Drug Overdose; Excitatory Amino Acid Antagonists; Humans; Lamotrigine; Male; Middle | 2012 |
Focal parietal necrosis of the sigmoid due to atypical neuroleptics: a case report.
Topics: Adult; Anti-Anxiety Agents; Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Citalopram | 2012 |
Evaluation of lamotrigine toxicity reported to poison centers.
Topics: Adolescent; Adult; Age Distribution; Anticonvulsants; Child; Child, Preschool; Drug Overdose; Female | 2004 |
The relevance of monitoring lamotrigine serum concentrations in chronic pain patients.
Topics: Administration, Oral; Adult; Analgesics; Chronic Disease; Cytochrome P-450 Enzyme System; Dose-Respo | 2006 |
Self-poisoning with lamotrigine and pregabalin.
Topics: Adult; Anticonvulsants; Drug Overdose; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Pregabali | 2007 |
Lamotrigine overdose in a child.
Topics: Anticonvulsants; Child, Preschool; Drug Overdose; Epilepsy; Female; Humans; Lamotrigine; Triazines | 2007 |
Acute lamotrigine overdose in an adolescent.
Topics: Adolescent; Antidepressive Agents; Depressive Disorder; Diagnosis, Differential; Drug Overdose; Emer | 2007 |
Seizures and altered mental status after lamotrigine overdose.
Topics: Adult; Anticonvulsants; Consciousness; Drug Overdose; Humans; Lamotrigine; Seizures; Triazines | 2007 |
Choreiform dyskinesia following isolated lamotrigine overdose.
Topics: Adult; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Chorea; Drug Overdose; Dyskinesia, Drug- | 2008 |
Overdose with gabapentin and lamotrigine.
Topics: Acetates; Adolescent; Amines; Anticonvulsants; Cyclohexanecarboxylic Acids; Drug Overdose; Female; G | 1997 |
Lamotrigine childhood overdose.
Topics: Anticonvulsants; Child, Preschool; Drug Overdose; Epilepsy, Tonic-Clonic; Gastric Lavage; Humans; La | 1998 |
Lamotrigine distribution in two postmortem cases.
Topics: Adult; Anticonvulsants; Drug Overdose; Female; Gas Chromatography-Mass Spectrometry; Humans; Lamotri | 2000 |
Lamotrigine overdose in an adult.
Topics: Adult; Anticonvulsants; Drug Overdose; Female; Humans; Lamotrigine; Suicide, Attempted; Triazines | 2000 |
Toxicologic causes of giggling.
Topics: Adolescent; Anticonvulsants; Diagnosis, Differential; Drug Overdose; Female; Humans; Lamotrigine; La | 2001 |
Stupor from lamotrigine toxicity.
Topics: Anticonvulsants; Coma; Drug Overdose; Epilepsy, Complex Partial; Female; Humans; Lamotrigine; Middle | 2001 |