lamotrigine has been researched along with Diabetic Neuropathies in 7 studies
Diabetic Neuropathies: Peripheral, autonomic, and cranial nerve disorders that are associated with DIABETES MELLITUS. These conditions usually result from diabetic microvascular injury involving small blood vessels that supply nerves (VASA NERVORUM). Relatively common conditions which may be associated with diabetic neuropathy include third nerve palsy (see OCULOMOTOR NERVE DISEASES); MONONEUROPATHY; mononeuropathy multiplex; diabetic amyotrophy; a painful POLYNEUROPATHY; autonomic neuropathy; and thoracoabdominal neuropathy. (From Adams et al., Principles of Neurology, 6th ed, p1325)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients (n=360 per study) with painful diabetic neuropathy were randomized to receive lamotrigine 200, 300, or 400 mg daily or placebo during the 19-week treatment phase, including a 7-week dose-escalation phase and a 12-week, fixed-dose maintenance phase." | 2.73 | Lamotrigine for treatment of pain associated with diabetic neuropathy: results of two randomized, double-blind, placebo-controlled studies. ( Blum, D; Corder, C; Grainger, J; Kirby, L; Quessy, S; Safirstein, B; Silver, M; Tuchman, M; Vinik, AI; White, J; Wilks, K, 2007) |
| " Assessment for pain relief, overall improvement and adverse events were carried out." | 2.73 | Randomized double-blind study comparing the efficacy and safety of lamotrigine and amitriptyline in painful diabetic neuropathy. ( Bhansali, A; Hota, D; Jose, VM; Pandhi, P, 2007) |
| "Lamotrigine is a sodium channel blocker that inhibits the neuronal release of glutamate." | 1.30 | Effects of intrathecally administered lamotrigine, a glutamate release inhibitor, on short- and long-term models of hyperalgesia in rats. ( Klamt, JG, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 6 (85.71) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hong, HB | 1 |
| Xu, RJ | 1 |
| Maeda, K | 1 |
| Yasuda, H | 1 |
| Vinik, AI | 1 |
| Tuchman, M | 1 |
| Safirstein, B | 1 |
| Corder, C | 1 |
| Kirby, L | 1 |
| Wilks, K | 1 |
| Quessy, S | 1 |
| Blum, D | 1 |
| Grainger, J | 1 |
| White, J | 1 |
| Silver, M | 1 |
| Jose, VM | 1 |
| Bhansali, A | 1 |
| Hota, D | 1 |
| Pandhi, P | 1 |
| Klamt, JG | 1 |
| McCleane, GJ | 1 |
| Eisenberg, E | 1 |
| Lurie, Y | 1 |
| Braker, C | 1 |
| Daoud, D | 1 |
| Ishay, A | 1 |
3 reviews available for lamotrigine and Diabetic Neuropathies
| Article | Year |
|---|---|
[Progress on painful diabetic peripheral neuropathy treated by integrative medicine].
Topics: Amines; Amitriptyline; Analgesics; Animals; Antidepressive Agents, Tricyclic; Blood Glucose; Cyclohe | 2005 |
[Symptomatic treatment of painful diabetic neuropathy].
Topics: Amines; Anti-Asthmatic Agents; Anticonvulsants; Antidepressive Agents; Antitussive Agents; Cyclohexa | 2005 |
Lamotrigine in the management of neuropathic pain: a review of the literature.
Topics: Analgesics; Diabetic Neuropathies; Humans; Lamotrigine; Triazines; Trigeminal Neuralgia | 2000 |
3 trials available for lamotrigine and Diabetic Neuropathies
| Article | Year |
|---|---|
Lamotrigine for treatment of pain associated with diabetic neuropathy: results of two randomized, double-blind, placebo-controlled studies.
Topics: Diabetic Neuropathies; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Lamotr | 2007 |
Randomized double-blind study comparing the efficacy and safety of lamotrigine and amitriptyline in painful diabetic neuropathy.
Topics: Adolescent; Adult; Aged; Algorithms; Amitriptyline; Analgesics, Non-Narcotic; Calcium Channel Blocke | 2007 |
Lamotrigine reduces painful diabetic neuropathy: a randomized, controlled study.
Topics: Diabetic Neuropathies; Female; Humans; Lamotrigine; Male; Middle Aged; Pain Measurement; Triazines | 2001 |
1 other study available for lamotrigine and Diabetic Neuropathies
| Article | Year |
|---|---|
Effects of intrathecally administered lamotrigine, a glutamate release inhibitor, on short- and long-term models of hyperalgesia in rats.
Topics: Analgesics; Animals; Diabetic Neuropathies; Dinoprostone; Disease Models, Animal; Dose-Response Rela | 1998 |