lamotrigine has been researched along with Dermatitis Medicamentosa in 84 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "These open-label data provide preliminary evidence that lamotrigine may be an effective treatment option for patients with refractory bipolar disorder; however, potential benefits must be weighed against potential side effects, including rash." | 9.09 | Spectrum of activity of lamotrigine in treatment-refractory bipolar disorder. ( Andersen, J; Ascher, JA; Bolden-Watson, C; Bowden, CL; Calabrese, JR; Cookson, J; Keck, PE; McElroy, SL; Rhodes, L; Zhou, J, 1999) |
| "To correlate lamotrigine (LTG) serum concentrations (levels) with tolerability in patients with epilepsy." | 8.82 | Correlating lamotrigine serum concentrations with tolerability in patients with epilepsy. ( Adams, DJ; Bazil, CW; Buchsbaum, R; Du, Y; Hager, M; Hirsch, LJ; Morrell, MJ; Resor, SR; Spencer, HT; Straka, T; Weintraub, D, 2004) |
| "To report a case of lamotrigine-induced drug rash with eosinophilia and systemic symptoms (DRESS) syndrome with pancreatitis as the initial visceral involvement." | 7.76 | First report of lamotrigine-induced drug rash with eosinophilia and systemic symptoms syndrome with pancreatitis. ( Augusto, JF; Croue, A; Dib, N; Lerolle, N; Mercat, A; Peres, M; Roquin, G, 2010) |
| "To evaluate the effect of lamotrigine (LTG) on several humoral and cellular immune functions in children with epilepsy and the change in immunological status in patients with LTG-induced rash." | 7.70 | Lamotrigine hypersensitivity in childhood epilepsy. ( Iannetti, P; Pacifici, R; Raucci, U; Zuccaro, P, 1998) |
| "To examine the safety of lamotrigine (LTG) used in general practice to treat epilepsy." | 7.69 | Safety of long-term lamotrigine in epilepsy. ( Freemantle, SN; Mackay, FJ; Mann, RD; Pearce, GL; Wilton, LV, 1997) |
| "Falling due to startle-induced seizures (SISs) often leads to injury." | 5.37 | Lamotrigine is favourable for startle-induced seizures. ( Fujiwara, T; Ikeda, H; Imai, K; Inoue, Y; Shigematsu, H; Shishido, T; Takahashi, Y; Takayama, R, 2011) |
| "We assessed rash incidence in 100 patients with DSM-IV bipolar disorder instructed, for their first 3 months taking lamotrigine, to avoid other new medicines and new foods, cosmetics, conditioners, deodorants, detergents, and fabric softeners, as well as sunburn and exposure to poison ivy/oak." | 5.11 | Dermatology precautions and slower titration yield low incidence of lamotrigine treatment-emergent rash. ( Alarcon, AM; Becker, OV; Chandler, RA; Ketter, TA; Nowakowska, C; O'Keeffe, CM; Schumacher, MR; Wang, PW, 2005) |
| "These open-label data provide preliminary evidence that lamotrigine may be an effective treatment option for patients with refractory bipolar disorder; however, potential benefits must be weighed against potential side effects, including rash." | 5.09 | Spectrum of activity of lamotrigine in treatment-refractory bipolar disorder. ( Andersen, J; Ascher, JA; Bolden-Watson, C; Bowden, CL; Calabrese, JR; Cookson, J; Keck, PE; McElroy, SL; Rhodes, L; Zhou, J, 1999) |
| "To correlate lamotrigine (LTG) serum concentrations (levels) with tolerability in patients with epilepsy." | 4.82 | Correlating lamotrigine serum concentrations with tolerability in patients with epilepsy. ( Adams, DJ; Bazil, CW; Buchsbaum, R; Du, Y; Hager, M; Hirsch, LJ; Morrell, MJ; Resor, SR; Spencer, HT; Straka, T; Weintraub, D, 2004) |
| "Lamotrigine (LTG) is a novel antiepileptic drug (AED) with a spectrum of activity in animal models of epilepsy similar to that of phenytoin and carbamazepine." | 4.79 | Lamotrigine. ( Messenheimer, JA, 1995) |
| " All had dermatological manifestations, eosinophilia and systemic (haematological and hepatic) manifestations that could be attributed to treatment with aromatic AEDs (carbamazepine, 2 patients; lamotrigine, 3 patients; phenytoin, 3 patients)." | 3.77 | Risk factors associated with DRESS syndrome produced by aromatic and non-aromatic antipiletic drugs. ( Kochen, S; Pereira de Silva, N; Piquioni, P; Saidon, P, 2011) |
| " The usual maintenance dosage of lamotrigine is 200 to 500 mg daily given in two divided doses." | 3.77 | The clinical efficacy of lamotrigine as an antiepileptic drug. ( Pellock, JM, 1994) |
| "To report a case of lamotrigine-induced drug rash with eosinophilia and systemic symptoms (DRESS) syndrome with pancreatitis as the initial visceral involvement." | 3.76 | First report of lamotrigine-induced drug rash with eosinophilia and systemic symptoms syndrome with pancreatitis. ( Augusto, JF; Croue, A; Dib, N; Lerolle, N; Mercat, A; Peres, M; Roquin, G, 2010) |
| "A previous study conducted in Taiwan found a 100% association between HLA-B*1502 allele and carbamazepine-induced Stevens-Johnson syndrome (SJS) in Han Chinese subjects, with an extremely high odds ratio compared with carbamazepine-tolerant subjects (odds ratio = 2,504)." | 3.74 | Association between HLA-B*1502 allele and antiepileptic drug-induced cutaneous reactions in Han Chinese. ( Baum, L; Cheng, AS; Kwan, P; Lau, KM; Man, CB; Ng, MH; Yu, E, 2007) |
| "A 43-year-old man developed a skin eruption characterized by 'macules with blisters' typical to Stevens-Johnson syndrome, as well as erosions of the lips and buccal mucosa, 2 weeks after he had started treatment with lamotrigine." | 3.73 | Drug Rash with eosinophilia and systemic symptoms versus Stevens-Johnson Syndrome--a case that indicates a stumbling block in the current classification. ( Davidovici, B; Mahlab, K; Matz, H; Orion, E; Sthoeger, ZM; Wolf, R, 2006) |
| "This postmarketing surveillance study of lamotrigine (LTG) was performed to provide complementary data to large-scale Prescription-Event Monitoring study with a retrospective case records survey in five tertiary referral epilepsy centres in the United Kingdom." | 3.71 | Adverse event monitoring in lamotrigine patients: a pharmacoepidemiologic study in the United Kingdom. ( Mawer, GE; Sander, JW; Wong, IC, 2001) |
| "To evaluate the effect of lamotrigine (LTG) on several humoral and cellular immune functions in children with epilepsy and the change in immunological status in patients with LTG-induced rash." | 3.70 | Lamotrigine hypersensitivity in childhood epilepsy. ( Iannetti, P; Pacifici, R; Raucci, U; Zuccaro, P, 1998) |
| "To examine the safety of lamotrigine (LTG) used in general practice to treat epilepsy." | 3.69 | Safety of long-term lamotrigine in epilepsy. ( Freemantle, SN; Mackay, FJ; Mann, RD; Pearce, GL; Wilton, LV, 1997) |
| "Lamotrigine was well-tolerated and effective for HIV-associated neuropathic pain in patients receiving neurotoxic antiretroviral therapy." | 2.71 | Lamotrigine for HIV-associated painful sensory neuropathies: a placebo-controlled trial. ( Baird, BJ; Barrett, P; Clifford, D; Hammer, AE; McArthur, JC; Olney, R; Ross, D; Simpson, DM; So, Y, 2003) |
| " The adverse effect (AE) profile of this combination needs clarification." | 2.69 | Adding lamotrigine to valproate: incidence of rash and other adverse effects. Postmarketing Antiepileptic Drug Survey (PADS) Group. ( Faught, E; French, J; Harden, C; Jacobson, M; Montouris, G; Morris, G; Rosenfeld, W, 1999) |
| "The major treatment-emergent AE were infection (50%, 8 of 16) and sleep disturbance (19%, 3 of 16)." | 2.68 | Lamotrigine adjunctive therapy in childhood epileptic encephalopathy (the Lennox Gastaut syndrome). ( Donaldson, JA; Glauser, TA; Olberding, LS, 1997) |
| "The overall incidence of skin rash with LTG therapy was 9." | 2.52 | Risk of a lamotrigine-related skin rash: current meta-analysis and postmarketing cohort analysis. ( Huang, DH; Huang, XS; Jia, WQ; Lang, SY; Tian, CL; Wang, XQ; Xiong, J; Xu, WH; Yu, SY; Zhang, JT, 2015) |
| "Rash was the only adverse effect causing discontinuation (N = 7)." | 2.46 | Lamotrigine adjunctive therapy for refractory generalized tonic-clonic seizures. ( Leong, K; Marson, AG; Tjia-Leong, E, 2010) |
| "Serious drug eruptions associated with lamotrigine were rare." | 2.41 | Rash in multicenter trials of lamotrigine in mood disorders: clinical relevance and management. ( Bowden, CL; Calabrese, JR; Frye, MA; Goldberg, JF; Goodwin, FK; Kusumakar, V; Sachs, GS; Shelton, MD; Sullivan, JR; Suppes, T, 2002) |
| " However, it should be remembered that the proportion of persons with this side effect is much reduced when the correct dosage is used, and the sliding scale of dosage starts with sufficiently low doses." | 2.41 | [Characteristics and indications of lamotrigine]. ( Rufo-Campos, M, 2002) |
| "Lamotrigine is a novel anticonvulsant, which has proven to be effective both as add-on and monotherapy." | 2.41 | The tolerability of lamotrigine in children. ( Giorgi, L; Messenheimer, JA; Risner, ME, 2000) |
| " These rates reflect lamotrigine dosing and concomitant AEDs used in these trials, both of which are risk factors for rash." | 2.40 | Rash in adult and pediatric patients treated with lamotrigine. ( Messenheimer, JA, 1998) |
| " Risk of serious rash may possibly be lessened by strict adherence to manufacturer's dosing guidelines, particularly in patients who are at higher risk: those on concurrent VPA and in the pediatric population." | 2.40 | Lamotrigine-associated rash: risk/benefit considerations in adults and children. ( Besag, FM; Brodie, MJ; Dooley, JM; Duchowny, MS; Guberman, AH; Pellock, JM; Richens, A; Stern, RS; Trevathan, E, 1999) |
| " By November 1992 about 5,800 patient-years' experience of adverse effects had been compiled." | 2.39 | Safety of lamotrigine. ( Richens, A, 1994) |
| "The mechanism of drug-induced skin rash is not well understood." | 1.91 | Potential Involvement of Sulfotransferase in the Mechanism of Lamotrigine-induced Skin Rash. ( Bairam, A; Cao, Y; Liu, MC; Uetrecht, J, 2023) |
| "She was diagnosed with left frontal lobe epilepsy, and a lamotrigine regimen was initiated." | 1.40 | Seizure freedom after lamotrigine rash: a peculiar phenomenon in epilepsy. ( Iwasaki, M; Jin, K; Kakisaka, Y; Kato, K; Nakasato, N, 2014) |
| "Falling due to startle-induced seizures (SISs) often leads to injury." | 1.37 | Lamotrigine is favourable for startle-induced seizures. ( Fujiwara, T; Ikeda, H; Imai, K; Inoue, Y; Shigematsu, H; Shishido, T; Takahashi, Y; Takayama, R, 2011) |
| "Lamotrigine (LTG) is a commonly used antiepileptic drug." | 1.37 | Hla-B alleles and lamotrigine-induced cutaneous adverse drug reactions in the Han Chinese population. ( Gao, MM; Liao, WP; Liu, XR; Min, FL; Shi, YW; Yu, MJ; Zan, LX, 2011) |
| " An adverse effect profile, as well as efficacy of monotherapy, was obtained through a face-to-face interview with the patient at each visit." | 1.36 | Adverse effects of carbamazepine, phenytoin, valproate and lamotrigine monotherapy in epileptic adult Chinese patients. ( Wang, X; Xi, Z; Yan, Y; Zeng, K, 2010) |
| "Severe rash is rare when using the currently recommended titration rate." | 1.33 | Predictors of Lamotrigine-associated rash. ( Buchsbaum, R; Hager, M; Hirsch, LJ; Resor, SR; Spencer, HT; Straka, T; Weintraub, DB, 2006) |
| "This syndrome is accompanied by fever, rash, lymphadenopathy, eosinophilia and affects parenchymal organs." | 1.32 | [Anticonvulsant hypersensitivity syndrome]. ( Papp, Z; Török, L, 2004) |
| " From our series of 254 prospectively registered adult patients treated with LTG at a dosage of 25-100 mg/ day, the incidence of allergic and non-allergic skin reactions was 5." | 1.31 | Lamotrigine-related skin rashes in adults. ( Huang, CW; Lai, ML; Tsai, JJ, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 29 (34.52) | 18.2507 |
| 2000's | 27 (32.14) | 29.6817 |
| 2010's | 24 (28.57) | 24.3611 |
| 2020's | 4 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Fong, SL | 1 |
| Lim, KS | 1 |
| Hariraj, V | 1 |
| Lee, SC | 1 |
| Wo, WK | 1 |
| Ramli, A | 1 |
| Ho, JH | 1 |
| Lai, PSM | 1 |
| Ng, WL | 1 |
| Cao, Y | 1 |
| Bairam, A | 1 |
| Liu, MC | 1 |
| Uetrecht, J | 1 |
| Reed, KL | 1 |
| Quinn, KB | 1 |
| Gust, AJ | 1 |
| Bresnahan, R | 1 |
| Panebianco, M | 1 |
| Marson, AG | 2 |
| Li, W | 1 |
| Wang, J | 1 |
| Lin, H | 1 |
| Shen, G | 1 |
| Kim, BK | 1 |
| Jung, JW | 1 |
| Kim, TB | 1 |
| Chang, YS | 1 |
| Park, HS | 1 |
| Moon, J | 2 |
| Lee, ST | 2 |
| Jung, KH | 2 |
| Jung, KY | 2 |
| Chu, K | 2 |
| Lee, SK | 3 |
| Kang, HR | 2 |
| Park, HW | 2 |
| Papadavid, E | 1 |
| Evangelia, P | 1 |
| Panayiotides, I | 1 |
| Ioannis, P | 1 |
| Makris, M | 1 |
| Michael, M | 1 |
| Giatrakou, S | 1 |
| Sophia, G | 1 |
| Dalamaga, M | 1 |
| Maria, D | 1 |
| Stavrianeas, N | 2 |
| Rigopoulos, D | 1 |
| Dimitrios, R | 1 |
| Li, LJ | 1 |
| Hu, FY | 1 |
| Wu, XT | 1 |
| An, DM | 1 |
| Yan, B | 1 |
| Zhou, D | 1 |
| Chou, YC | 1 |
| Chao, FH | 1 |
| Chou, YH | 1 |
| Kakisaka, Y | 1 |
| Jin, K | 1 |
| Kato, K | 1 |
| Iwasaki, M | 1 |
| Nakasato, N | 1 |
| Fricke-Galindo, I | 1 |
| Martínez-Juárez, IE | 1 |
| Monroy-Jaramillo, N | 1 |
| Jung-Cook, H | 1 |
| Falfán-Valencia, R | 1 |
| Ortega-Vázquez, A | 1 |
| Alonso-Vilatela, ME | 1 |
| López-López, M | 1 |
| Wang, XQ | 1 |
| Xiong, J | 1 |
| Xu, WH | 1 |
| Yu, SY | 1 |
| Huang, XS | 1 |
| Zhang, JT | 1 |
| Tian, CL | 1 |
| Huang, DH | 1 |
| Jia, WQ | 1 |
| Lang, SY | 1 |
| Jang, HW | 1 |
| Kim, SW | 1 |
| Cho, YJ | 1 |
| Heo, K | 1 |
| Lee, BI | 1 |
| Jang, IJ | 2 |
| Lee, MG | 1 |
| Kim, WJ | 1 |
| Lee, JH | 1 |
| Park, HK | 1 |
| Sunwoo, JS | 1 |
| Byun, JI | 1 |
| Lim, JA | 1 |
| Kim, TJ | 1 |
| Shin, JW | 1 |
| Jeon, D | 1 |
| Kim, DW | 1 |
| Yu, KS | 1 |
| Saeki, H | 1 |
| Yamada, K | 1 |
| Morikawa, N | 1 |
| Asahina, A | 1 |
| Ochiai, T | 1 |
| Iijima, M | 1 |
| Camia, F | 1 |
| Pisciotta, L | 1 |
| Morana, G | 1 |
| Schiaffino, MC | 1 |
| Renna, S | 1 |
| Carrera, P | 1 |
| Ferrari, M | 1 |
| Baglietto, MG | 1 |
| Veneselli, E | 1 |
| Siri, L | 1 |
| Mancardi, MM | 1 |
| Bushardt, RL | 1 |
| Taillia, H | 1 |
| Alla, P | 1 |
| Fournier, B | 1 |
| Bounolleau, P | 1 |
| Ouologem, M | 1 |
| Ricard, D | 1 |
| Sallansonnet-Froment, M | 1 |
| de Greslan, T | 1 |
| Renard, JL | 1 |
| Aouam, K | 1 |
| Ben Romdhane, F | 1 |
| Loussaief, C | 1 |
| Salem, R | 1 |
| Toumi, A | 1 |
| Belhadjali, H | 1 |
| Chaabane, A | 1 |
| Boughattas, NA | 1 |
| Chakroun, M | 1 |
| Zeng, K | 1 |
| Wang, X | 1 |
| Xi, Z | 1 |
| Yan, Y | 1 |
| Roquin, G | 1 |
| Peres, M | 1 |
| Lerolle, N | 1 |
| Dib, N | 1 |
| Mercat, A | 1 |
| Croue, A | 1 |
| Augusto, JF | 1 |
| Tjia-Leong, E | 1 |
| Leong, K | 1 |
| Shi, YW | 1 |
| Min, FL | 1 |
| Liu, XR | 1 |
| Zan, LX | 1 |
| Gao, MM | 1 |
| Yu, MJ | 1 |
| Liao, WP | 1 |
| Fuertes, L | 1 |
| García-Cano, I | 1 |
| Ortiz de Frutos, J | 1 |
| Vanaclocha, F | 1 |
| Pereira de Silva, N | 1 |
| Piquioni, P | 1 |
| Kochen, S | 1 |
| Saidon, P | 1 |
| Do-Pham, G | 1 |
| Charachon, A | 1 |
| Duong, TA | 1 |
| Thille, AW | 1 |
| Benhaiem, N | 1 |
| Bagot, M | 1 |
| Chosidow, O | 1 |
| Roujeau, JC | 1 |
| Wolkenstein, P | 1 |
| Valeyrie-Allanore, L | 1 |
| Ikeda, H | 2 |
| Imai, K | 1 |
| Shigematsu, H | 1 |
| Shishido, T | 1 |
| Takayama, R | 1 |
| Fujiwara, T | 1 |
| Takahashi, Y | 1 |
| Inoue, Y | 1 |
| Yeom, JS | 1 |
| Park, JS | 1 |
| Seo, JH | 1 |
| Park, ES | 1 |
| Lim, JY | 1 |
| Park, CH | 1 |
| Woo, HO | 1 |
| Youn, HS | 1 |
| Chow, JC | 1 |
| Huang, CW | 2 |
| Fang, CW | 1 |
| Wu, YJ | 1 |
| Tsai, JJ | 2 |
| Nakai, N | 1 |
| Katoh, N | 1 |
| Cabanillas, M | 1 |
| Suárez-Amor, O | 1 |
| Ramírez-Santos, A | 1 |
| González-Vilas, D | 1 |
| Núñez-Acevedo, B | 1 |
| Monteagudo, B | 1 |
| de las Heras, C | 1 |
| Rufo-Campos, M | 1 |
| Calabrese, JR | 2 |
| Sullivan, JR | 1 |
| Bowden, CL | 2 |
| Suppes, T | 1 |
| Goldberg, JF | 1 |
| Sachs, GS | 1 |
| Shelton, MD | 1 |
| Goodwin, FK | 1 |
| Frye, MA | 1 |
| Kusumakar, V | 2 |
| Labiner, DM | 1 |
| Lai, ML | 1 |
| Simpson, DM | 2 |
| McArthur, JC | 2 |
| Olney, R | 2 |
| Clifford, D | 1 |
| So, Y | 1 |
| Ross, D | 1 |
| Baird, BJ | 1 |
| Barrett, P | 1 |
| Hammer, AE | 1 |
| Harman, KE | 1 |
| Morris, SD | 1 |
| Higgins, EM | 1 |
| Papp, Z | 1 |
| Török, L | 1 |
| Hirsch, LJ | 2 |
| Weintraub, D | 1 |
| Du, Y | 1 |
| Buchsbaum, R | 2 |
| Spencer, HT | 2 |
| Hager, M | 2 |
| Straka, T | 2 |
| Bazil, CW | 1 |
| Adams, DJ | 1 |
| Resor, SR | 2 |
| Morrell, MJ | 1 |
| Nielsen, JN | 1 |
| Licht, RW | 1 |
| Fogh, K | 1 |
| Subuh Surja, AA | 1 |
| Brotzge, KE | 1 |
| El-Mallakh, RS | 1 |
| Ketter, TA | 1 |
| Wang, PW | 1 |
| Chandler, RA | 1 |
| Alarcon, AM | 1 |
| Becker, OV | 1 |
| Nowakowska, C | 1 |
| O'Keeffe, CM | 1 |
| Schumacher, MR | 1 |
| Weintraub, DB | 1 |
| Wolf, R | 1 |
| Davidovici, B | 1 |
| Matz, H | 1 |
| Mahlab, K | 1 |
| Orion, E | 1 |
| Sthoeger, ZM | 1 |
| Gélisse, P | 1 |
| Crespel, A | 1 |
| Lu, W | 1 |
| Uetrecht, JP | 1 |
| Alvestad, S | 1 |
| Lydersen, S | 1 |
| Brodtkorb, E | 1 |
| Man, CB | 1 |
| Kwan, P | 1 |
| Baum, L | 1 |
| Yu, E | 1 |
| Lau, KM | 1 |
| Cheng, AS | 1 |
| Ng, MH | 1 |
| Kopcsányi, H | 1 |
| Feldmann, J | 1 |
| Péch, Z | 1 |
| Jurcsik, A | 1 |
| Tavernor, SJ | 1 |
| Wong, IC | 2 |
| Newton, R | 1 |
| Brown, SW | 1 |
| Schaub, JE | 1 |
| Williamson, PJ | 1 |
| Barnes, EW | 1 |
| Trewby, PN | 1 |
| Pellock, JM | 2 |
| Richens, A | 2 |
| Brodie, MJ | 2 |
| Li, LM | 1 |
| Russo, M | 1 |
| O'Donoghue, MF | 1 |
| Duncan, JS | 1 |
| Sander, JW | 2 |
| Messenheimer, JA | 3 |
| Mims, J | 1 |
| Penovich, P | 1 |
| Ritter, F | 1 |
| Frost, MD | 1 |
| Donaldson, JA | 1 |
| Glauser, TA | 1 |
| Olberding, LS | 1 |
| Jones, D | 1 |
| Chhiap, V | 1 |
| Resor, S | 1 |
| Appel, G | 1 |
| Grossman, ME | 1 |
| Yatham, LN | 1 |
| Mehta, U | 1 |
| Sachs, B | 1 |
| Rönnau, AC | 1 |
| von Schmiedeberg, S | 1 |
| Ruzicka, T | 1 |
| Gleichmann, E | 1 |
| Schuppe, HC | 1 |
| Feeney, J | 1 |
| Lilley, LL | 1 |
| Guanci, R | 1 |
| Scheen, AJ | 1 |
| Buzan, RD | 1 |
| Dubovsky, SL | 1 |
| Mackay, FJ | 1 |
| Wilton, LV | 2 |
| Pearce, GL | 1 |
| Freemantle, SN | 1 |
| Mann, RD | 1 |
| Tugendhaft, P | 1 |
| Simonart, T | 1 |
| Iannetti, P | 1 |
| Raucci, U | 1 |
| Zuccaro, P | 1 |
| Pacifici, R | 1 |
| Chapman, MS | 1 |
| Zug, KA | 1 |
| Lewis, LD | 1 |
| Lovell, RW | 1 |
| McElroy, SL | 1 |
| Cookson, J | 1 |
| Andersen, J | 1 |
| Keck, PE | 1 |
| Rhodes, L | 1 |
| Bolden-Watson, C | 1 |
| Zhou, J | 1 |
| Ascher, JA | 1 |
| Guberman, AH | 1 |
| Besag, FM | 1 |
| Dooley, JM | 1 |
| Duchowny, MS | 1 |
| Stern, RS | 1 |
| Trevathan, E | 1 |
| Faught, E | 1 |
| Morris, G | 1 |
| Jacobson, M | 1 |
| French, J | 1 |
| Harden, C | 1 |
| Montouris, G | 1 |
| Rosenfeld, W | 1 |
| Matsuo, F | 1 |
| Bozikas, V | 1 |
| Vartzopoulos, D | 1 |
| Phocas, C | 1 |
| Karavatos, A | 1 |
| Kaprinis, G | 1 |
| Giorgi, L | 1 |
| Risner, ME | 1 |
| Khan, A | 1 |
| Godbold, J | 1 |
| Ebel-Frommer, K | 1 |
| Acharya, NV | 1 |
| Shakir, SA | 1 |
| Mawer, GE | 1 |
| Hsiao, CJ | 1 |
| Lee , JY | 1 |
| Wong, TW | 1 |
| Sheu, HM | 1 |
| Anderson, GD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Protocol Establishment for the Prevention of Lamotrigine-induced Skin Rash in Epilepsy Patients: A Pilot Study[NCT03220256] | Phase 2 | 30 participants (Anticipated) | Interventional | 2016-08-02 | Recruiting | ||
| HLA Screening in Reducing the Risk of Antiepileptic Drug-induced Cutaneous Adverse Reactions: a Multicenter Clinical Study[NCT03184597] | 4,000 participants (Anticipated) | Interventional | 2017-08-01 | Recruiting | |||
| A Pilot Study of Prophylactic Management of Lamotrigine for Bipolar Disorder in Pregnant Women[NCT03774641] | 20 participants (Anticipated) | Observational | 2018-12-03 | Recruiting | |||
| The BrainDrugs-Epilepsy Study: A Prospective Open-label Cohort Precision Medicine Study in Epilepsy[NCT05450822] | 550 participants (Anticipated) | Observational | 2022-02-18 | Recruiting | |||
| A Preliminary Study of the Efficacy and Safety of Carbamazepine in Severe Liver Disease Due to Alpha-1 Antitrypsin Deficiency[NCT01379469] | Phase 2 | 20 participants (Actual) | Interventional | 2012-01-31 | Terminated | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
16 reviews available for lamotrigine and Dermatitis Medicamentosa
| Article | Year |
|---|---|
Lamotrigine add-on therapy for drug-resistant generalised tonic-clonic seizures.
Topics: Anticonvulsants; Chemotherapy, Adjuvant; Dizziness; Drug Eruptions; Drug Resistant Epilepsy; Epileps | 2020 |
HLA-A∗24:02 associated with lamotrigine-induced cutaneous adverse drug reactions: A systematic review and meta-analysis.
Topics: Anticonvulsants; Drug Eruptions; HLA-A24 Antigen; Humans; Lamotrigine; Pharmacogenomic Variants; Ris | 2020 |
Risk of a lamotrigine-related skin rash: current meta-analysis and postmarketing cohort analysis.
Topics: Anticonvulsants; Drug Eruptions; Exanthema; Humans; Incidence; Lamotrigine; Randomized Controlled Tr | 2015 |
Lamotrigine adjunctive therapy for refractory generalized tonic-clonic seizures.
Topics: Anticonvulsants; Chemotherapy, Adjuvant; Drug Eruptions; Epilepsy, Tonic-Clonic; Exanthema; Humans; | 2010 |
[Characteristics and indications of lamotrigine].
Topics: Adult; Animals; Anticonvulsants; Child; Clinical Trials as Topic; Drug Eruptions; Drug Interactions; | 2002 |
Rash in multicenter trials of lamotrigine in mood disorders: clinical relevance and management.
Topics: Anticonvulsants; Antimanic Agents; Bipolar Disorder; Cross-Sectional Studies; Depressive Disorder, M | 2002 |
Correlating lamotrigine serum concentrations with tolerability in patients with epilepsy.
Topics: Anticonvulsants; Dose-Response Relationship, Drug; Drug Eruptions; Drug Interactions; Drug Therapy, | 2004 |
The clinical efficacy of lamotrigine as an antiepileptic drug.
Topics: Adult; Anticonvulsants; Child; Clinical Trials as Topic; Drug Eruptions; Epilepsy; Humans; Lamotrigi | 1994 |
Safety of lamotrigine.
Topics: Adult; Anticonvulsants; Child; Clinical Trials as Topic; Drug Eruptions; Epilepsy; Female; Humans; L | 1994 |
Lamotrigine versus other antiepileptic drugs: a star rating system is born.
Topics: Adolescent; Adult; Anticonvulsants; Attitude of Health Personnel; Clinical Trials as Topic; Drug Adm | 1994 |
Lamotrigine.
Topics: Animals; Anticonvulsants; Clinical Trials as Topic; Disease Models, Animal; Drug Administration Sche | 1995 |
Rash in adult and pediatric patients treated with lamotrigine.
Topics: Adult; Anticonvulsants; Child, Preschool; Clinical Trials as Topic; Drug Eruptions; Humans; Incidenc | 1998 |
Lamotrigine-associated rash: risk/benefit considerations in adults and children.
Topics: Adult; Age Factors; Anticonvulsants; Child; Drug Eruptions; Epilepsy; Humans; Incidence; Lamotrigine | 1999 |
Lamotrigine.
Topics: Adolescent; Adult; Animals; Anticonvulsants; Child; Clinical Trials as Topic; Diplopia; Dizziness; D | 1999 |
The tolerability of lamotrigine in children.
Topics: Adolescent; Anticonvulsants; Child; Clinical Trials as Topic; Drug Eruptions; Humans; Lamotrigine; S | 2000 |
Children versus adults: pharmacokinetic and adverse-effect differences.
Topics: Adolescent; Age Factors; Anticonvulsants; Chemical and Drug Induced Liver Injury; Child; Child, Pres | 2002 |
7 trials available for lamotrigine and Dermatitis Medicamentosa
| Article | Year |
|---|---|
Lamotrigine for HIV-associated painful sensory neuropathies: a placebo-controlled trial.
Topics: Adult; Aged; Analgesics, Non-Narcotic; Anti-HIV Agents; Dideoxynucleosides; Double-Blind Method; Dru | 2003 |
Dermatology precautions and slower titration yield low incidence of lamotrigine treatment-emergent rash.
Topics: Adult; Ambulatory Care; Anticonvulsants; Bipolar Disorder; Cohort Studies; Drug Administration Sched | 2005 |
The clinical efficacy of lamotrigine as an antiepileptic drug.
Topics: Adult; Anticonvulsants; Child; Clinical Trials as Topic; Drug Eruptions; Epilepsy; Humans; Lamotrigi | 1994 |
Lamotrigine adjunctive therapy in childhood epileptic encephalopathy (the Lennox Gastaut syndrome).
Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Child; Child, Preschool; Databases, Factual; Drug A | 1997 |
Spectrum of activity of lamotrigine in treatment-refractory bipolar disorder.
Topics: Adult; Aged; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Drug Eruptions; Drug Therapy, Comb | 1999 |
Adding lamotrigine to valproate: incidence of rash and other adverse effects. Postmarketing Antiepileptic Drug Survey (PADS) Group.
Topics: Adolescent; Adult; Child; Dizziness; Drug Eruptions; Drug Hypersensitivity; Drug Therapy, Combinatio | 1999 |
A placebo-controlled trial of lamotrigine for painful HIV-associated neuropathy.
Topics: Adult; Analgesics; Analysis of Variance; Double-Blind Method; Drug Eruptions; Exanthema; Female; HIV | 2000 |
62 other studies available for lamotrigine and Dermatitis Medicamentosa
| Article | Year |
|---|---|
Incidence of Antiseizure Medication-Induced Severe Cutaneous Adverse Reactions in Malaysia.
Topics: Anticonvulsants; Drug Eruptions; Epilepsy; HLA Antigens; Humans; Incidence; Lamotrigine; Malaysia; P | 2022 |
Potential Involvement of Sulfotransferase in the Mechanism of Lamotrigine-induced Skin Rash.
Topics: Drug Eruptions; Exanthema; Humans; Lamotrigine; Nevirapine; Oxides; Sertraline; Sulfates; Sulfotrans | 2023 |
Lamotrigine-induced cutaneous pseudolymphoma.
Topics: Anticonvulsants; Child; Drug Eruptions; Female; Humans; Lamotrigine; Pseudolymphoma; Scalp Dermatose | 2019 |
HLA-A*31:01 and lamotrigine-induced severe cutaneous adverse drug reactions in a Korean population.
Topics: Anticonvulsants; Drug Eruptions; Genetic Predisposition to Disease; Genotype; HLA-A Antigens; Humans | 2017 |
Pityriasis rosea-like eruption associated with lamotrigine.
Topics: Adult; Anticonvulsants; Drug Eruptions; Drug Hypersensitivity; Female; Humans; Lamotrigine; Myocloni | 2013 |
Predictive markers for carbamazepine and lamotrigine-induced maculopapular exanthema in Han Chinese.
Topics: Adult; Alleles; Anticonvulsants; Asian People; Biomarkers; Carbamazepine; Case-Control Studies; Chin | 2013 |
Rapid development of severe skin rash after adding valproic acid in a case of bipolar depression treated with low-dose lamotrigine.
Topics: Antimanic Agents; Bipolar Disorder; Drug Eruptions; Drug Interactions; Drug Therapy, Combination; Fe | 2014 |
Seizure freedom after lamotrigine rash: a peculiar phenomenon in epilepsy.
Topics: Anticonvulsants; Drug Eruptions; Epilepsy, Frontal Lobe; Exanthema; Female; Humans; Lamotrigine; Mid | 2014 |
HLA-A*02:01:01/-B*35:01:01/-C*04:01:01 haplotype associated with lamotrigine-induced maculopapular exanthema in Mexican Mestizo patients.
Topics: Adolescent; Adult; Aged; Carbamazepine; Drug Eruptions; Drug-Related Side Effects and Adverse Reacti | 2014 |
GWAS identifies two susceptibility loci for lamotrigine-induced skin rash in patients with epilepsy.
Topics: Anticonvulsants; Asian People; Cohort Studies; Drug Eruptions; Epilepsy; Exanthema; Genetic Predispo | 2015 |
The HLA-A*2402/Cw*0102 haplotype is associated with lamotrigine-induced maculopapular eruption in the Korean population.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Drug Eruptions; Epilepsy; Female; Gene Frequency; Genotype | 2015 |
Severe drug eruptions due to lamotrigine in Japan based on data from the relief system of the Pharmaceuticals and Medical Devices Agency.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Databases, Factual; Drug Erupti | 2017 |
Combined early treatment in hemiplegic attacks related to CACNA1A encephalopathy with brain oedema: Blocking the cascade?
Topics: Anticonvulsants; Brain Edema; Calcium Channels; Child; Dexamethasone; Drug Eruptions; Female; Fructo | 2017 |
Anticonvulsant hypersensitivity syndrome and drug-induced hepatic injury.
Topics: Adult; Anticonvulsants; Chemical and Drug Induced Liver Injury; Drug Eruptions; Female; Humans; Lamo | 2009 |
[Anticonvulsant hypersensitivity syndrome and lamotrigine-associated anticonvulsant hypersensitivity syndrome].
Topics: Adult; Aged; Anticonvulsants; Bipolar Disorder; Drug Eruptions; Drug Hypersensitivity; Eosinophilia; | 2009 |
Hypersensitivity syndrome induced by anticonvulsants: possible cross-reactivity between carbamazepine and lamotrigine.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Cross Reactions; Drug Eruptions; Drug Hypersensitivity; | 2009 |
Adverse effects of carbamazepine, phenytoin, valproate and lamotrigine monotherapy in epileptic adult Chinese patients.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; China; Drug Eruptions; Epilepsy; Female; Hu | 2010 |
First report of lamotrigine-induced drug rash with eosinophilia and systemic symptoms syndrome with pancreatitis.
Topics: Aged; Drug Eruptions; Eosinophilia; Exanthema; Humans; Lamotrigine; Male; Pancreatitis; Syndrome; Tr | 2010 |
Hla-B alleles and lamotrigine-induced cutaneous adverse drug reactions in the Han Chinese population.
Topics: Adolescent; Aged; Alleles; Anticonvulsants; Asian People; Base Sequence; Child; Child, Preschool; Ch | 2011 |
[Patch testing increases the likelihood of recognizing lamotrigine as a cause of drug-induced rash].
Topics: Antidepressive Agents; Antimanic Agents; Cyclohexanols; Depressive Disorder; Drug Eruptions; Drug Th | 2011 |
Risk factors associated with DRESS syndrome produced by aromatic and non-aromatic antipiletic drugs.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Anticonvulsants; Carbamazepine; Disease Susceptibility; | 2011 |
Drug reaction with eosinophilia and systemic symptoms and severe involvement of digestive tract: description of two cases.
Topics: Adrenal Cortex Hormones; Adult; Aged; Anticonvulsants; Antirheumatic Agents; Colitis, Ulcerative; Dr | 2011 |
Lamotrigine is favourable for startle-induced seizures.
Topics: Activities of Daily Living; Age of Onset; Anticonvulsants; Atrophy; Brain; Child; Drug Eruptions; El | 2011 |
aPTT prolongation and skin eruption possibly associated with lamotrigine monotherapy in a paediatric patient.
Topics: Anticonvulsants; Blood Chemical Analysis; Blood Coagulation Factors; Child; Drug Eruptions; Electroe | 2011 |
Lamotrigine-induced hypersensitivity syndrome in a Han Chinese patient with the HLA-B 5801 genotype.
Topics: Adult; Anticonvulsants; Asian People; Drug Eruptions; Drug Hypersensitivity; Epilepsy; Female; Genot | 2013 |
Value of a lymphocyte transformation test for diagnosis of maculopapular and erythema multiforme type drug eruption due to lamotrigine: three case reports.
Topics: Adult; Aged; Anticonvulsants; Drug Eruptions; Female; Humans; Lamotrigine; Lymphocyte Activation; Mi | 2012 |
Lamotrigine induced subacute cutaneous lupus erythematous.
Topics: Anticonvulsants; Drug Eruptions; Female; Humans; Lamotrigine; Lupus Erythematosus, Cutaneous; Middle | 2012 |
Lamotrigine and rash: scratching beneath the surface.
Topics: Adult; Adverse Drug Reaction Reporting Systems; Anticonvulsants; Antimanic Agents; Bipolar Disorder; | 2002 |
Lamotrigine-related skin rashes in adults.
Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Drug Eruptions; Female; Humans; Incidence; Lamotrig | 2002 |
Persistent anticonvulsant hypersensitivity syndrome responding to ciclosporin.
Topics: Adult; Anticonvulsants; Biopsy; Cyclosporine; Dermatologic Agents; Drug Eruptions; Drug Therapy, Com | 2003 |
[Anticonvulsant hypersensitivity syndrome].
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Eruptions; Drug | 2004 |
Two cases of acneiform eruption associated with lamotrigine.
Topics: Acne Vulgaris; Adult; Anticonvulsants; Bipolar Disorder; Drug Eruptions; Humans; Lamotrigine; Male; | 2004 |
Serious rash with lamotrigine after carbamazepine discontinuation: a case report.
Topics: Anticonvulsants; Carbamazepine; Cytochrome P-450 Enzyme System; Drug Eruptions; Humans; Lamotrigine; | 2005 |
Predictors of Lamotrigine-associated rash.
Topics: Adolescent; Adult; Age Factors; Ambulatory Care; Anticonvulsants; Child; Drug Administration Schedul | 2006 |
Drug Rash with eosinophilia and systemic symptoms versus Stevens-Johnson Syndrome--a case that indicates a stumbling block in the current classification.
Topics: Adult; Diagnosis, Differential; Drug Eruptions; Eosinophilia; Humans; Lamotrigine; Male; Stevens-Joh | 2006 |
[Reintroduction of treatment with lamotrigine in combination with valproate after an initial allergic skin reaction].
Topics: Adult; Anticonvulsants; Drug Eruptions; Drug Therapy, Combination; Epilepsy, Absence; Female; Humans | 2006 |
Possible bioactivation pathways of lamotrigine.
Topics: Animals; Anticonvulsants; Biotransformation; Chromatography, High Pressure Liquid; Cytosol; Drug Eru | 2007 |
Rash from antiepileptic drugs: influence by gender, age, and learning disability.
Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Carbamazepine; Comorbidity; Drug Eruptions; Epileps | 2007 |
Association between HLA-B*1502 allele and antiepileptic drug-induced cutaneous reactions in Han Chinese.
Topics: Adolescent; Adult; Alleles; Anticonvulsants; Asian People; Carbamazepine; Case-Control Studies; Chil | 2007 |
Association between HLA-B*1502 allele and antiepileptic drug-induced cutaneous reactions in Han Chinese.
Topics: Adolescent; Adult; Alleles; Anticonvulsants; Asian People; Carbamazepine; Case-Control Studies; Chil | 2007 |
Association between HLA-B*1502 allele and antiepileptic drug-induced cutaneous reactions in Han Chinese.
Topics: Adolescent; Adult; Alleles; Anticonvulsants; Asian People; Carbamazepine; Case-Control Studies; Chil | 2007 |
Association between HLA-B*1502 allele and antiepileptic drug-induced cutaneous reactions in Han Chinese.
Topics: Adolescent; Adult; Alleles; Anticonvulsants; Asian People; Carbamazepine; Case-Control Studies; Chil | 2007 |
[Difficulties in detecting the causative agent of an adverse drug reaction in a complicated case].
Topics: Administration, Cutaneous; Administration, Oral; Anticonvulsants; Antidepressive Agents; Atorvastati | 2008 |
Rechallenge with lamotrigine after initial rash.
Topics: Adolescent; Adult; Anticonvulsants; Child; Dose-Response Relationship, Drug; Drug Administration Sch | 1995 |
Multisystem adverse reaction to lamotrigine.
Topics: Anticonvulsants; Ataxia; Disseminated Intravascular Coagulation; Drug Eruptions; Female; Humans; Lam | 1994 |
Allergic skin rash with lamotrigine and concomitant valproate therapy: evidence for an increased risk.
Topics: Adolescent; Adult; Anticonvulsants; Drug Eruptions; Female; Humans; Lamotrigine; Male; Middle Aged; | 1996 |
Treatment with high doses of lamotrigine in children and adolescents with refractory seizures.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Eruptio | 1997 |
Glaxo Wellcome epilepsy drug exhibits fatal side effects.
Topics: Adult; Anticonvulsants; Child; Death; Drug Eruptions; Drug Industry; Epilepsy; Humans; Lamotrigine; | 1997 |
Phenytoin-like hypersensitivity associated with lamotrigine.
Topics: Adult; Anticonvulsants; Drug Eruptions; Humans; Lamotrigine; Male; Phenytoin; Triazines | 1997 |
Lamotrigine treatment of rapid cycling bipolar disorder.
Topics: Adult; Aged; Anticonvulsants; Bipolar Disorder; Drug Administration Schedule; Drug Eruptions; Drug T | 1997 |
Lamotrigine and serious skin reactions.
Topics: Adult; Anticonvulsants; Child; Child, Preschool; Drug Eruptions; Drug Therapy, Combination; Humans; | 1997 |
Lamotrigine-induced Stevens-Johnson syndrome: demonstration of specific lymphocyte reactivity in vitro.
Topics: Adult; Anticonvulsants; Concanavalin A; Drug Eruptions; Drug Therapy, Combination; Half-Life; Humans | 1997 |
Diaminopyrimidines and severe cutaneous adverse reactions.
Topics: Acute Disease; Anticonvulsants; Antimalarials; Drug Eruptions; Humans; Lamotrigine; Pyrimethamine; P | 1997 |
A rash of oversights.
Topics: Adolescent; Age Factors; Anticonvulsants; Carbamazepine; Drug Eruptions; Drug Interactions; Drug Lab | 1997 |
[Lamotrigine (Lamictal)].
Topics: Anticonvulsants; Brain; Child; Child, Preschool; Drug Combinations; Drug Eruptions; Epilepsies, Part | 1997 |
Recurrence of lamotrigine-associated rash with rechallenge.
Topics: Adult; Anticonvulsants; Bipolar Disorder; Drug Eruptions; Humans; Lamotrigine; Male; Obsessive-Compu | 1998 |
Safety of long-term lamotrigine in epilepsy.
Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Age Factors; Aged; Anticonvulsants; Chil | 1997 |
Phenytoin-like hypersensitivity associated with lamotrigine.
Topics: Anticonvulsants; Dose-Response Relationship, Drug; Drug Eruptions; Exanthema; Humans; Lamotrigine; P | 1998 |
Lamotrigine hypersensitivity in childhood epilepsy.
Topics: Antibody Formation; Anticonvulsants; Child; Drug Eruptions; Epilepsy; Humans; Immunity, Cellular; La | 1998 |
Lamotrigine and phenobarbitone-associated hypersensitivity syndrome: resolution without corticosteroids.
Topics: Aged; Anticonvulsants; Drug Eruptions; Drug Therapy, Combination; Female; Humans; Lamotrigine; Lip D | 1998 |
Mood stabilizer combinations for bipolar disorder.
Topics: Acetates; Adolescent; Age Factors; Amines; Antimanic Agents; Bipolar Disorder; Child; Cyclohexanecar | 1999 |
Lamotrigine-induced rash after sun exposure.
Topics: Adult; Anticonvulsants; Bipolar Disorder; Drug Eruptions; Drug Therapy, Combination; Female; Haloper | 1999 |
Incompleteness of lamotrigine data.
Topics: Adult; Anticonvulsants; Child; Clinical Trials as Topic; Drug Eruptions; Female; Humans; Lamotrigine | 2001 |
Adverse event monitoring in lamotrigine patients: a pharmacoepidemiologic study in the United Kingdom.
Topics: Acetates; Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Amines; Anticonvulsants; | 2001 |
Extensive fixed drug eruption due to lamotrigine.
Topics: Anticonvulsants; Drug Eruptions; Humans; Lamotrigine; Male; Middle Aged; Triazines | 2001 |