lamotrigine has been researched along with Depression, Endogenous in 58 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "These analyses, conducted on a data set drawn from a previously reported, open-label, multicentre, prospective study, examined the effect of lamotrigine on mood in adults aged>or=50 years with epilepsy and co-morbid depressive symptoms." | 9.13 | Effects of lamotrigine on mood in older adults with epilepsy and co-morbid depressive symptoms: an open-label, multicentre, prospective study. ( Fakhoury, TA; Hammer, AE; Miller, JM; Vuong, A, 2008) |
| "To provide a qualitative, systematic update and review of the pharmacology, pharmacokinetics, efficacy in mood disorders, adverse effects, and costs of lamotrigine." | 8.81 | Lamotrigine update and its use in mood disorders. ( Hurley, SC, 2002) |
| " Lamotrigine (LTG) is an effective clinical treatment for epilepsy associated with absence seizures." | 7.78 | Lamotrigine ameliorates seizures and psychiatric comorbidity in a rat model of spontaneous absence epilepsy. ( Chen, SD; Huang, HY; Lee, HW; Shaw, FZ, 2012) |
| "The aim of this study was to test the effectiveness and safety of lamotrigine in maintenance of manic and depressive symptom control in pediatric bipolar disorder (PBD)." | 7.75 | Effectiveness of lamotrigine in maintaining symptom control in pediatric bipolar disorder. ( Carbray, JA; Henry, DB; Mohammed, T; Moss, M; Pavuluri, MN; Sweeney, JA, 2009) |
| "Aripiprazole is an atypical antipsychotic compound that is approved by the U." | 6.73 | Aripiprazole therapy in 20 older adults with bipolar disorder: a 12-week, open-label trial. ( Blow, FC; Cassidy, KA; Coconcea, N; Hays, RW; Ignacio, RV; Meyer, WJ; Sajatovic, M, 2008) |
| "Patients with bipolar disorder in a euthymic state (Young's Mania Rating Scale (YMRS) score <12, and 21-item Hamilton Depression Rating Scale (HAM-D) score <7) for at least two months, having already received either olanzapine or lamotrigine as the maintenance treatment were recruited." | 5.19 | Olanzapine is superior to lamotrigine in the prevention of bipolar depression: a naturalistic observational study. ( Lee, MS; Lo, MC; Pan, PY; Yang, EL; Yeh, CB, 2014) |
| " This study aimed to identify and compare factors of a 31-item version of the HDRS (HDRS-31) in large samples of patients with bipolar depression and Major Depressive Disorder (MDD), then examine the responsiveness of such factors to lamotrigine compared with placebo in the bipolar depressed sample." | 5.17 | A factor analytic study in bipolar depression, and response to lamotrigine. ( Bowden, CL; Calabrese, JR; Evoniuk, G; Hadzi-Pavlovic, D; Mitchell, PB, 2013) |
| "To identify baseline clinical factors associated with acute treatment response in depressed older adults with bipolar disorder (BD) receiving lamotrigine." | 5.16 | Correlates of treatment response in depressed older adults with bipolar disorder. ( Al Jurdi, RK; Bialko, C; Cassidy, KA; Gildengers, A; Gyulai, L; Mulsant, BH; Sajatovic, M; Tatsuoka, C; Young, RC, 2012) |
| "These analyses, conducted on a data set drawn from a previously reported, open-label, multicentre, prospective study, examined the effect of lamotrigine on mood in adults aged>or=50 years with epilepsy and co-morbid depressive symptoms." | 5.13 | Effects of lamotrigine on mood in older adults with epilepsy and co-morbid depressive symptoms: an open-label, multicentre, prospective study. ( Fakhoury, TA; Hammer, AE; Miller, JM; Vuong, A, 2008) |
| "The anticonvulsant lamotrigine has been reported to be efficacious and well tolerated as monotherapy in the treatment of bipolar patients as well as in treatment-refractory bipolar disorder." | 5.10 | Lamotrigine as an augmentation agent in treatment-resistant depression. ( Barbee, JG; Jamhour, NJ, 2002) |
| " Preliminary data suggest that lamotrigine, an established antiepileptic drug, may be effective for both the depression and mania associated with bipolar disorder." | 5.09 | A double-blind placebo-controlled study of lamotrigine monotherapy in outpatients with bipolar I depression. Lamictal 602 Study Group. ( Ascher, JA; Bowden, CL; Calabrese, JR; Monaghan, E; Rudd, GD; Sachs, GS, 1999) |
| " As the result of the detailed analysis of the literature the author recommends lamotrigine, carbamazepine and oxcarbazepine as first choice antiepileptic drug for epileptic patients suffering from depressive disorder, too." | 4.84 | [Effects of antiepileptic drugs on mood of people with epilepsy]. ( Rajna, P, 2007) |
| "To provide a qualitative, systematic update and review of the pharmacology, pharmacokinetics, efficacy in mood disorders, adverse effects, and costs of lamotrigine." | 4.81 | Lamotrigine update and its use in mood disorders. ( Hurley, SC, 2002) |
| "The use of lamotrigine is a point of discrepancy among the diverse guidelines published on the management of bipolar disorder (BD)." | 3.78 | Clinical factors leading to lamotrigine prescription in bipolar outpatients: subanalysis of the SIN-DEPRES study. ( Balanzá-Martínez, V; Cobaleda, S; de Arce, R; Franch Valverde, JI; Grande, I; Iglesias Lorenzo, FG; Jiménez-Arriero, M; Vieta, E; Zaragoza, S, 2012) |
| " Lamotrigine (LTG) is an effective clinical treatment for epilepsy associated with absence seizures." | 3.78 | Lamotrigine ameliorates seizures and psychiatric comorbidity in a rat model of spontaneous absence epilepsy. ( Chen, SD; Huang, HY; Lee, HW; Shaw, FZ, 2012) |
| "The aim of this study was to test the effectiveness and safety of lamotrigine in maintenance of manic and depressive symptom control in pediatric bipolar disorder (PBD)." | 3.75 | Effectiveness of lamotrigine in maintaining symptom control in pediatric bipolar disorder. ( Carbray, JA; Henry, DB; Mohammed, T; Moss, M; Pavuluri, MN; Sweeney, JA, 2009) |
| "To study the effectiveness of adding lamotrigine to the treatment of inpatient geriatric patients with bipolar disorder (BD) who were in the depressed phase and had been on lithium and valproate for at least 3 months." | 3.71 | Lamotrigine use in geriatric patients with bipolar depression. ( Conn, DK; Robillard, M, 2002) |
| "Lamotrigine was associated with higher odds of treatment response compared with placebo in the melancholic subgroup but not in the nonmelancholic subgroup." | 2.87 | Melancholic Symptoms in Bipolar II Depression and Responsiveness to Lamotrigine in an Exploratory Pilot Study. ( Balbuena, L; Bowen, R; Peters, EM, 2018) |
| "Aripiprazole is an atypical antipsychotic compound that is approved by the U." | 2.73 | Aripiprazole therapy in 20 older adults with bipolar disorder: a 12-week, open-label trial. ( Blow, FC; Cassidy, KA; Coconcea, N; Hays, RW; Ignacio, RV; Meyer, WJ; Sajatovic, M, 2008) |
| "Both lamotrigine and lithium were superior to placebo at prolonging the time to intervention for any mood episode (lamotrigine vs placebo, P =." | 2.71 | A placebo-controlled 18-month trial of lamotrigine and lithium maintenance treatment in recently manic or hypomanic patients with bipolar I disorder. ( Asghar, SA; Bowden, CL; Calabrese, JR; DeVeaugh-Geiss, J; Earl, N; Hompland, M; Montgomery, P; Sachs, G; Smoot, TM; Yatham, LN, 2003) |
| "Lamotrigine was statistically superior to placebo on the Clinical Global Impressions scale at endpoint, both in absolute terms (mean +/- SD Clinical Global Impressions-Severity of Illness scores: lamotrigine, 2." | 2.71 | A double-blind, randomized, placebo-controlled trial of augmentation with lamotrigine or placebo in patients concomitantly treated with fluoxetine for resistant major depressive episodes. ( Barbosa, L; Berk, M; Vorster, M, 2003) |
| "Lamotrigine was statistically superior to placebo at prolonging the time to intervention for a depressive episode (p = ." | 2.71 | A placebo-controlled 18-month trial of lamotrigine and lithium maintenance treatment in recently depressed patients with bipolar I disorder. ( Ascher, J; Behnke, K; Bowden, CL; Calabrese, JR; DeVeaugh-Geiss, J; Earl, N; Mehtonen, OP; Montgomery, P; Paska, W; Sachs, G; Yatham, LN, 2003) |
| "While both unipolar and bipolar depression have serious detrimental effects on patient QOL, our results suggest that some aspects of QOL may be worse in bipolar depression." | 2.71 | Quality of life in patients with bipolar I depression: data from 920 patients. ( Davis, KH; Fieve, RR; Harris, SD; Krishnan, AA; Lecrubier, Y; Yatham, LN, 2004) |
| "The benefits of lamotrigine in unipolar depression have been inconsistently noted in a number of studies." | 2.48 | Lamotrigine in the treatment of unipolar depression with and without comorbidities: a literature review. ( Ali, R; Zavodnick, AD, 2012) |
| "A major challenge in the treatment of bipolar depression is the tendency for antidepressant medications, particularly tricyclic antidepressants, to precipitate episodes of mania, or to increase cycle frequency or symptom intensity." | 2.44 | The role of mood stabilisers in the treatment of the depressive facet of bipolar disorders. ( Bourin, M; Prica, C, 2007) |
| "However, the treatment of bipolar depression is hampered by the limited number and varying quality of available studies of pharmacologic treatments to guide clinical decision making." | 2.43 | The evidence for antidepressant use in bipolar depression. ( Ostacher, MJ, 2006) |
| "Lamotrigine has also demonstrated significant efficacy in recent studies and has been approved by the FDA." | 2.42 | Bipolar depression: an overview. ( Oral, ET; Vahip, S, 2004) |
| "Unfortunately, therapy appropriate for unipolar depression can increase the risk of manic switch or cycle acceleration in bipolar disorder, especially in those with a family history of bipolarity and suicide, although some antidepressants may be useful in some bipolar patients." | 1.33 | A different depression: clinical distinctions between bipolar and unipolar depression. ( Bowden, CL, 2005) |
| "A significant number of patients with unipolar depression fail to achieve remission after one or a series of antidepressants." | 1.32 | Lamotrigine augmentation in unipolar depression. ( Hara, C; Rocha, FL, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (10.34) | 18.2507 |
| 2000's | 32 (55.17) | 29.6817 |
| 2010's | 19 (32.76) | 24.3611 |
| 2020's | 1 (1.72) | 2.80 |
| Authors | Studies |
|---|---|
| Sprague, J | 1 |
| Wisner, KL | 1 |
| Bogen, DL | 1 |
| Peters, EM | 1 |
| Bowen, R | 1 |
| Balbuena, L | 2 |
| Mitchell, PB | 1 |
| Hadzi-Pavlovic, D | 1 |
| Evoniuk, G | 1 |
| Calabrese, JR | 8 |
| Bowden, CL | 10 |
| McIntyre, RS | 1 |
| Cha, DS | 1 |
| Kim, RD | 1 |
| Mansur, RB | 1 |
| Pan, PY | 1 |
| Lee, MS | 1 |
| Lo, MC | 1 |
| Yang, EL | 1 |
| Yeh, CB | 1 |
| Bowen, RC | 1 |
| Baetz, M | 1 |
| Mintz, J | 2 |
| Tohen, M | 2 |
| Laurito, LD | 1 |
| Fontenelle, LF | 1 |
| Kahn, DA | 1 |
| Sümegi, A | 1 |
| Fakhoury, TA | 1 |
| Miller, JM | 1 |
| Hammer, AE | 1 |
| Vuong, A | 1 |
| Pavuluri, MN | 1 |
| Henry, DB | 1 |
| Moss, M | 1 |
| Mohammed, T | 1 |
| Carbray, JA | 1 |
| Sweeney, JA | 1 |
| Goldberg, JF | 1 |
| Saville, BR | 1 |
| Frye, MA | 3 |
| Ketter, TA | 1 |
| Suppes, T | 3 |
| Post, RM | 2 |
| Goodwin, FK | 1 |
| Swann, AC | 1 |
| Rätz Bravo, AE | 1 |
| Zimmermann, T | 1 |
| Haschke, M | 1 |
| Thomas, SP | 1 |
| Nandhra, HS | 1 |
| Jayaraman, A | 1 |
| Deligiannidis, KM | 1 |
| Machado, RA | 1 |
| Espinosa, AG | 1 |
| Melendrez, D | 1 |
| González, YR | 1 |
| García, VF | 1 |
| Rodríguez, YQ | 1 |
| Fuertes, L | 1 |
| García-Cano, I | 1 |
| Ortiz de Frutos, J | 1 |
| Vanaclocha, F | 1 |
| Zavodnick, AD | 1 |
| Ali, R | 1 |
| Gildengers, A | 1 |
| Tatsuoka, C | 1 |
| Bialko, C | 1 |
| Cassidy, KA | 2 |
| Al Jurdi, RK | 1 |
| Gyulai, L | 1 |
| Mulsant, BH | 1 |
| Young, RC | 1 |
| Sajatovic, M | 2 |
| Grande, I | 1 |
| Balanzá-Martínez, V | 1 |
| Jiménez-Arriero, M | 1 |
| Iglesias Lorenzo, FG | 1 |
| Franch Valverde, JI | 1 |
| de Arce, R | 1 |
| Zaragoza, S | 1 |
| Cobaleda, S | 1 |
| Vieta, E | 1 |
| Huang, HY | 1 |
| Lee, HW | 1 |
| Chen, SD | 1 |
| Shaw, FZ | 1 |
| Singh, V | 1 |
| Diler, RS | 1 |
| Ladouceur, CD | 1 |
| Segreti, A | 1 |
| Almeida, JR | 1 |
| Birmaher, B | 1 |
| Axelson, DA | 1 |
| Phillips, ML | 1 |
| Pan, LA | 1 |
| Barbee, JG | 1 |
| Jamhour, NJ | 1 |
| Robillard, M | 1 |
| Conn, DK | 1 |
| Rocha, FL | 1 |
| Hara, C | 1 |
| Sachs, G | 2 |
| Yatham, LN | 5 |
| Asghar, SA | 1 |
| Hompland, M | 1 |
| Montgomery, P | 2 |
| Earl, N | 2 |
| Smoot, TM | 1 |
| DeVeaugh-Geiss, J | 2 |
| Barbosa, L | 1 |
| Berk, M | 1 |
| Vorster, M | 1 |
| Behnke, K | 1 |
| Mehtonen, OP | 1 |
| Ascher, J | 1 |
| Paska, W | 1 |
| Leverich, GS | 1 |
| Nolen, WA | 1 |
| Kupka, RW | 1 |
| Altshuler, LL | 1 |
| McElroy, S | 1 |
| Keck, P | 1 |
| Grunze, H | 3 |
| Walden, J | 2 |
| Benazzi, F | 1 |
| Lecrubier, Y | 1 |
| Fieve, RR | 1 |
| Davis, KH | 1 |
| Harris, SD | 1 |
| Krishnan, AA | 1 |
| Oral, ET | 1 |
| Vahip, S | 1 |
| Gajwani, P | 1 |
| Forsthoff, A | 1 |
| Muzina, D | 1 |
| Amann, B | 1 |
| Gao, K | 1 |
| Elhaj, O | 1 |
| Howland, RH | 1 |
| Brown, EB | 1 |
| McElroy, SL | 1 |
| Keck, PE | 1 |
| Deldar, A | 1 |
| Adams, DH | 1 |
| Williamson, DJ | 1 |
| Ostacher, MJ | 1 |
| Bajbouj, M | 1 |
| Gallinat, J | 1 |
| Lang, UE | 1 |
| Hellen, F | 1 |
| Vesper, J | 1 |
| Lisanby, SH | 1 |
| Danker-Hopfe, H | 1 |
| Neu, P | 1 |
| Bourin, M | 1 |
| Prica, C | 1 |
| Reimers, A | 1 |
| Reinholt, G | 1 |
| Rajna, P | 1 |
| Coconcea, N | 1 |
| Ignacio, RV | 1 |
| Blow, FC | 1 |
| Hays, RW | 1 |
| Meyer, WJ | 1 |
| Skolnick, AA | 1 |
| Manack, L | 1 |
| Fatemi, SH | 1 |
| Woyshville, MJ | 1 |
| Kusumakar, V | 1 |
| Sachs, GS | 1 |
| Ascher, JA | 1 |
| Monaghan, E | 1 |
| Rudd, GD | 1 |
| Dallow, S | 1 |
| Maltese, TM | 1 |
| Shelton, MD | 1 |
| Rapport, DJ | 1 |
| Shirley, ER | 1 |
| Kimmel, SE | 1 |
| Caban, SJ | 1 |
| Hurley, SC | 1 |
| Normann, C | 1 |
| Hummel, B | 1 |
| Schärer, LO | 1 |
| Hörn, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison of Olanzapine and Lamotrigine in the Prevention of Recurrence of Depressive Episode in the Patients With Bipolar Disorders[NCT01864551] | Phase 4 | 60 participants (Actual) | Interventional | 2008-08-31 | Completed | ||
| Efficacy and Safety of Antidepressant Augmentation With Lamotrigine in Patients With Treatment-Resistant Depression[NCT00652171] | Phase 3 | 34 participants (Actual) | Interventional | 2004-01-31 | Completed | ||
| The Safety and Effectiveness of Probiotic Supplementation on Bipolar Depression: a Proof of Concept Randomized Controlled Trial[NCT02155972] | Phase 2 | 16 participants (Actual) | Interventional | 2013-05-31 | Terminated (stopped due to The trial was terminated because of inability to recruit the needed number of participants) | ||
| A Randomized, Double-blind, Double-dummy, Controlled Trial of Lithium Versus Paroxetine in Subjects With Major Depression Who Have a Family History of Bipolar Disorder or Completed Suicide - a Pilot Study[NCT00400088] | Phase 3 | 2 participants (Actual) | Interventional | 2007-06-30 | Terminated (stopped due to Recruitment difficulties) | ||
| Aripiprazole in Late Life Bipolar Disorder[NCT00194038] | Phase 4 | 20 participants (Actual) | Interventional | 2004-04-30 | Completed | ||
| Understanding the Neurocognitive Effects of Fecal Microbiota Transplantation in Major Depressive Disorder Patients With and Without Irritable Bowel Syndrome[NCT05174273] | Phase 2/Phase 3 | 180 participants (Anticipated) | Interventional | 2022-04-06 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
19 reviews available for lamotrigine and Depression, Endogenous
| Article | Year |
|---|---|
Pharmacotherapy for depression and bipolar disorder during lactation: A framework to aid decision making.
Topics: Antidepressive Agents; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Decision Making; De | 2020 |
A review of FDA-approved treatment options in bipolar depression.
Topics: Antidepressive Agents; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Benzhydryl Co | 2013 |
[Mood stabilizers--past, present and future].
Topics: Affect; Antimanic Agents; Bipolar Disorder; Calcium; Carbamazepine; Depressive Disorder; gamma-Amino | 2008 |
Pharmacologic mood destabilization: case vignettes.
Topics: Adult; Affect; Anticonvulsants; Atomoxetine Hydrochloride; Attention Deficit Disorder with Hyperacti | 2009 |
Systematic review of lamotrigine augmentation of treatment resistant unipolar depression (TRD).
Topics: Adolescent; Adult; Antimanic Agents; Depressive Disorder; Drug Resistance; Drug Synergism; Female; H | 2010 |
Therapeutic drug monitoring in pregnant and postpartum women: recommendations for SSRIs, lamotrigine, and lithium.
Topics: Anticonvulsants; Antimanic Agents; Depressive Disorder; Drug Monitoring; Epilepsy; Female; Humans; L | 2010 |
Clinical practice. Bipolar disorder--a focus on depression.
Topics: Adult; Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disord | 2011 |
Lamotrigine in the treatment of unipolar depression with and without comorbidities: a literature review.
Topics: Antimanic Agents; Anxiety Disorders; Borderline Personality Disorder; Comorbidity; Depressive Disord | 2012 |
A re-evaluation of the role of antidepressants in the treatment of bipolar depression: data from the Stanley Foundation Bipolar Network.
Topics: Adult; Affect; Antidepressive Agents; Bipolar Disorder; Depressive Disorder; Double-Blind Method; Dr | 2003 |
Newer anticonvulsants in the treatment of bipolar disorder.
Topics: Acetates; Amines; Anticonvulsants; Bipolar Disorder; Carbamazepine; Cyclohexanecarboxylic Acids; Dep | 2004 |
Bipolar depression: an overview.
Topics: Acute Disease; Antidepressive Agents; Antimanic Agents; Benzodiazepines; Bipolar Disorder; Chemoprev | 2004 |
Treatment options for bipolar depression.
Topics: Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Dep | 2005 |
Antiepileptic drugs in mood-disordered patients.
Topics: Anticonvulsants; Bipolar Disorder; Carbamazepine; Depressive Disorder; Humans; Lamotrigine; Treatmen | 2005 |
Anticonvulsant drug therapies.
Topics: Amines; Anticonvulsants; Bipolar Disorder; Carbamazepine; Cyclohexanecarboxylic Acids; Depressive Di | 2005 |
The evidence for antidepressant use in bipolar depression.
Topics: Anticonvulsants; Antidepressive Agents; Bipolar Disorder; Critical Pathways; Depressive Disorder; Hu | 2006 |
The role of mood stabilisers in the treatment of the depressive facet of bipolar disorders.
Topics: Affective Symptoms; Animals; Antimanic Agents; Bipolar Disorder; Carbamazepine; Depressive Disorder; | 2007 |
[Effects of antiepileptic drugs on mood of people with epilepsy].
Topics: Affect; Anticonvulsants; Antidepressive Agents; Carbamazepine; Depressive Disorder; Epilepsy; Fructo | 2007 |
Bipolar rapid cycling: focus on depression as its hallmark.
Topics: Anticonvulsants; Antidepressive Agents, Tricyclic; Bipolar Disorder; Comorbidity; Controlled Clinica | 2001 |
Lamotrigine update and its use in mood disorders.
Topics: Acetates; Aggression; Amines; Antidepressive Agents; Bipolar Disorder; Cyclohexanecarboxylic Acids; | 2002 |
16 trials available for lamotrigine and Depression, Endogenous
| Article | Year |
|---|---|
Melancholic Symptoms in Bipolar II Depression and Responsiveness to Lamotrigine in an Exploratory Pilot Study.
Topics: Adult; Antipsychotic Agents; Bipolar Disorder; Depressive Disorder; Double-Blind Method; Female; Hum | 2018 |
A factor analytic study in bipolar depression, and response to lamotrigine.
Topics: Adult; Antidepressive Agents; Bipolar Disorder; Depressive Disorder; Double-Blind Method; Drug Admin | 2013 |
Olanzapine is superior to lamotrigine in the prevention of bipolar depression: a naturalistic observational study.
Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Depressive Di | 2014 |
Effects of lamotrigine on mood in older adults with epilepsy and co-morbid depressive symptoms: an open-label, multicentre, prospective study.
Topics: Affect; Age of Onset; Aged; Aged, 80 and over; Anticonvulsants; Data Interpretation, Statistical; De | 2008 |
Correlates of treatment response in depressed older adults with bipolar disorder.
Topics: Aged; Aged, 80 and over; Antimanic Agents; Bipolar Disorder; Cholesterol; Depressive Disorder; Execu | 2012 |
Relative effectiveness of adjunctive risperidone on manic and depressive symptoms in mixed mania.
Topics: Adult; Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Depressive Disorder; Diagnostic an | 2013 |
Lamotrigine as an augmentation agent in treatment-resistant depression.
Topics: Adolescent; Adult; Aged; Antidepressive Agents; Anxiety Disorders; Bipolar Disorder; Chronic Disease | 2002 |
A placebo-controlled 18-month trial of lamotrigine and lithium maintenance treatment in recently manic or hypomanic patients with bipolar I disorder.
Topics: Adult; Anticonvulsants; Bipolar Disorder; Depressive Disorder; Double-Blind Method; Drug Administrat | 2003 |
A double-blind, randomized, placebo-controlled trial of augmentation with lamotrigine or placebo in patients concomitantly treated with fluoxetine for resistant major depressive episodes.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Depressive Disorder; Double-Blind Method; Drug Administrat | 2003 |
A placebo-controlled 18-month trial of lamotrigine and lithium maintenance treatment in recently depressed patients with bipolar I disorder.
Topics: Adult; Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Depressive Disorder; Dose-Response | 2003 |
Quality of life in patients with bipolar I depression: data from 920 patients.
Topics: Acute Disease; Adult; Antipsychotic Agents; Bipolar Disorder; Depressive Disorder; Double-Blind Meth | 2004 |
A 7-week, randomized, double-blind trial of olanzapine/fluoxetine combination versus lamotrigine in the treatment of bipolar I depression.
Topics: Adult; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Depressive Disorder | 2006 |
Motor cortex excitability after vagus nerve stimulation in major depression.
Topics: Adult; Benzodiazepines; Citalopram; Clomipramine; Clozapine; Depressive Disorder; Doxepin; Drug Ther | 2007 |
Aripiprazole therapy in 20 older adults with bipolar disorder: a 12-week, open-label trial.
Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Aripiprazole; Basal Ganglia Diseases; Bipolar Disorde | 2008 |
A double-blind placebo-controlled study of lamotrigine monotherapy in outpatients with bipolar I depression. Lamictal 602 Study Group.
Topics: Adult; Aged; Ambulatory Care; Anticonvulsants; Bipolar Disorder; Depressive Disorder; Dose-Response | 1999 |
Lamotrigine as adjunct to paroxetine in acute depression: a placebo-controlled, double-blind study.
Topics: Acute Disease; Adolescent; Adult; Aged; Anticonvulsants; Depressive Disorder; Double-Blind Method; D | 2002 |
23 other studies available for lamotrigine and Depression, Endogenous
| Article | Year |
|---|---|
Lamotrigine reduces affective instability in depressed patients with mixed mood and anxiety disorders.
Topics: Adult; Anxiety Disorders; Depressive Disorder; Female; Humans; Lamotrigine; Male; Middle Aged; Mood | 2014 |
Multi-state outcome analysis of treatments (MOAT): application of a new approach to evaluate outcomes in longitudinal studies of bipolar disorder.
Topics: Adult; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Depressive Disorder; Female; Humans | 2016 |
Hoarding Symptoms Respond to Treatment for Rapid Cycling Bipolar II Disorder.
Topics: Bipolar Disorder; Calcium Channel Blockers; Depressive Disorder; Dopamine Uptake Inhibitors; Hoardin | 2016 |
Effectiveness of lamotrigine in maintaining symptom control in pediatric bipolar disorder.
Topics: Adolescent; Antimanic Agents; Bipolar Disorder; Child; Depressive Disorder; Female; Humans; Lamotrig | 2009 |
Mood stabilization and destabilization during acute and continuation phase treatment for bipolar I disorder with lamotrigine or placebo.
Topics: Adult; Anticonvulsants; Antimanic Agents; Bipolar Disorder; Depressive Disorder; Female; Humans; Iat | 2009 |
Lamotrigine and bipolar disorder: new indication. Only after lithium, like other antiepileptics. Preventive effects in only one aspect of bipolar disorder, but with a risk of Lyell syndrome.
Topics: Anticonvulsants; Antimanic Agents; Bipolar Disorder; Depressive Disorder; Europe; Humans; Lamotrigin | 2009 |
[Lamotrigine and the skin].
Topics: Adult; Anti-Anxiety Agents; Anticonvulsants; Depressive Disorder; Diagnosis, Differential; Disruptiv | 2010 |
Suicidal risk and suicide attempts in people treated with antiepileptic drugs for epilepsy.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Comorbidity; Depressive Disorder; Electroencephalography; | 2011 |
[Patch testing increases the likelihood of recognizing lamotrigine as a cause of drug-induced rash].
Topics: Antidepressive Agents; Antimanic Agents; Cyclohexanols; Depressive Disorder; Drug Eruptions; Drug Th | 2011 |
Clinical factors leading to lamotrigine prescription in bipolar outpatients: subanalysis of the SIN-DEPRES study.
Topics: Adult; Aged; Antimanic Agents; Bipolar Disorder; Depressive Disorder; Female; Guideline Adherence; H | 2012 |
Lamotrigine ameliorates seizures and psychiatric comorbidity in a rat model of spontaneous absence epilepsy.
Topics: Animals; Anticonvulsants; Anxiety Disorders; Comorbidity; Depressive Disorder; Disease Models, Anima | 2012 |
Neural correlates of treatment response in depressed bipolar adolescents during emotion processing.
Topics: Adolescent; Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Aripiprazole; Bipolar Diso | 2013 |
Lamotrigine use in geriatric patients with bipolar depression.
Topics: Aged; Aged, 80 and over; Antimanic Agents; Bipolar Disorder; Depressive Disorder; Dose-Response Rela | 2002 |
Lamotrigine augmentation in unipolar depression.
Topics: Adolescent; Adult; Aged; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; | 2003 |
How to treat bipolar II depression and bipolar II mixed depression?
Topics: Antidepressive Agents; Bipolar Disorder; Depressive Disorder; Humans; Lamotrigine; Triazines | 2004 |
A different depression: clinical distinctions between bipolar and unipolar depression.
Topics: Antidepressive Agents; Antimanic Agents; Bipolar Disorder; Depressive Disorder; Diagnosis, Different | 2005 |
Acute lamotrigine overdose in an adolescent.
Topics: Adolescent; Antidepressive Agents; Depressive Disorder; Diagnosis, Differential; Drug Overdose; Emer | 2007 |
Science reporters hear wide range of recent data at 12th annual conference.
Topics: Acetates; Aged; AIDS Vaccines; American Medical Association; Amines; Animals; Anticonvulsants; beta- | 1993 |
Antidepressant effects of lamotrigine in rapid cycling bipolar disorder.
Topics: Anticonvulsants; Bipolar Disorder; Depressive Disorder; Humans; Lamotrigine; Lithium; Male; Middle A | 1996 |
An open study of lamotrigine in refractory bipolar depression.
Topics: Adolescent; Adult; Anticonvulsants; Antidepressive Agents; Bipolar Disorder; Cohort Studies; Depress | 1997 |
Recruitment for drug trials.
Topics: Antidepressive Agents; Depressive Disorder; Humans; Lamotrigine; Patient Selection; Triazines | 1998 |
Adjunctive lamotrigine treatment for major depression.
Topics: Adult; Antidepressive Agents; Clonazepam; Cyclohexanols; Depressive Disorder; Drug Therapy, Combinat | 1999 |
Introduction: the role of anticonvulsants as mood stabilizers.
Topics: Anticonvulsants; Bipolar Disorder; Depressive Disorder; Humans; Lamotrigine; Lithium; Terminology as | 2001 |