lamotrigine has been researched along with Death, Sudden in 11 studies
Death, Sudden: The abrupt cessation of all vital bodily functions, manifested by the permanent loss of total cerebral, respiratory, and cardiovascular functions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "S Food and Drug Administration warnings that lamotrigine, a common sodium channel modulating anti-seizure medication (NaM-ASM), could increase the risk of sudden death in patients with structural or ischaemic cardiac disease, however, its implications for Sudden Unexpected Death in Epilepsy (SUDEP) are unclear." | 8.31 | Risk of sudden unexpected death in epilepsy (SUDEP) with lamotrigine and other sodium channel-modulating antiseizure medications. ( Auvrez, C; Barnard, S; Berkovic, SF; Chen, Z; Cook, MJ; D'Souza, W; Devinsky, O; Friedman, D; Kwan, P; Laze, J; Nightscales, R; O'Brien, TJ; Perucca, P; Sivathamboo, S; Tao, G, 2023) |
| "To estimate the incidence of sudden unexpected death in epilepsy (SUDEP) in Rogaland County, Norway, in the period August 1 1995-July 31 2005, and to investigate whether use of lamotrigine (LTG) was associated with increased risk in female patients or other subgroups." | 7.78 | Increased risk of sudden unexpected death in epilepsy in females using lamotrigine: a nested, case-control study. ( Aurlien, D; Gjerstad, L; Larsen, JP; Taubøll, E, 2012) |
| "Epilepsy was induced in seven C57Bl/6 mice by injections of KA (20 mg/kg) on days 1 and 5, which produced severe acute seizures and spontaneous seizures 10 days later." | 5.40 | Cardiac phenomena during kainic-acid induced epilepsy and lamotrigine antiepileptic therapy. ( Dibué, M; Hänggi, D; Hescheler, J; Kamp, MA; Neumaier, F; Schneider, T; Steiger, HJ, 2014) |
| "S Food and Drug Administration warnings that lamotrigine, a common sodium channel modulating anti-seizure medication (NaM-ASM), could increase the risk of sudden death in patients with structural or ischaemic cardiac disease, however, its implications for Sudden Unexpected Death in Epilepsy (SUDEP) are unclear." | 4.31 | Risk of sudden unexpected death in epilepsy (SUDEP) with lamotrigine and other sodium channel-modulating antiseizure medications. ( Auvrez, C; Barnard, S; Berkovic, SF; Chen, Z; Cook, MJ; D'Souza, W; Devinsky, O; Friedman, D; Kwan, P; Laze, J; Nightscales, R; O'Brien, TJ; Perucca, P; Sivathamboo, S; Tao, G, 2023) |
| "To estimate the incidence of sudden unexpected death in epilepsy (SUDEP) in Rogaland County, Norway, in the period August 1 1995-July 31 2005, and to investigate whether use of lamotrigine (LTG) was associated with increased risk in female patients or other subgroups." | 3.78 | Increased risk of sudden unexpected death in epilepsy in females using lamotrigine: a nested, case-control study. ( Aurlien, D; Gjerstad, L; Larsen, JP; Taubøll, E, 2012) |
| "This postmarketing surveillance study of lamotrigine (LTG) was performed to provide complementary data to large-scale Prescription-Event Monitoring study with a retrospective case records survey in five tertiary referral epilepsy centres in the United Kingdom." | 3.71 | Adverse event monitoring in lamotrigine patients: a pharmacoepidemiologic study in the United Kingdom. ( Mawer, GE; Sander, JW; Wong, IC, 2001) |
| "The present study was conducted to determine the rate of sudden unexplained death in epilepsy (SUDEP) in a well-defined cohort of patients included in the lamotrigine (LTG) clinical development database." | 3.69 | Sudden unexplained death in epilepsy: observations from a large clinical development program. ( Annegers, JF; Brodie, MJ; Brown, S; Cierpial, MA; Earl, NL; Leestma, JE; Schraeder, P; Siscovick, D; Tennis, PS; Wannamaker, BB, 1997) |
| "We report a case of Takotsubo syndrome after epilepsy, and review the literature." | 2.48 | Takotsubo syndrome (TKS): a possible mechanism of sudden unexplained death in epilepsy (SUDEP). ( Dubuisson, N; Dupuis, F; Dupuis, M; Evrard, F; van Rijckevorsel, K; Van Robays, P, 2012) |
| "Cardiac arrhythmia has been suggested as a cause of death in some patients with SUDEP." | 1.72 | Rare sudden unexpected death in epilepsy SCN5A variants cause changes in channel function implicating cardiac arrhythmia as a cause of death. ( Bagnall, RD; Berkovic, SF; Reid, CA; Scheffer, IE; Semsarian, C; Soh, MS, 2022) |
| "Epilepsy was induced in seven C57Bl/6 mice by injections of KA (20 mg/kg) on days 1 and 5, which produced severe acute seizures and spontaneous seizures 10 days later." | 1.40 | Cardiac phenomena during kainic-acid induced epilepsy and lamotrigine antiepileptic therapy. ( Dibué, M; Hänggi, D; Hescheler, J; Kamp, MA; Neumaier, F; Schneider, T; Steiger, HJ, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 5 (45.45) | 24.3611 |
| 2020's | 2 (18.18) | 2.80 |
| Authors | Studies |
|---|---|
| Soh, MS | 1 |
| Bagnall, RD | 1 |
| Semsarian, C | 1 |
| Scheffer, IE | 1 |
| Berkovic, SF | 2 |
| Reid, CA | 1 |
| Nightscales, R | 1 |
| Barnard, S | 1 |
| Laze, J | 1 |
| Chen, Z | 1 |
| Tao, G | 1 |
| Auvrez, C | 1 |
| Sivathamboo, S | 1 |
| Cook, MJ | 1 |
| Kwan, P | 1 |
| Friedman, D | 2 |
| D'Souza, W | 1 |
| Perucca, P | 1 |
| Devinsky, O | 1 |
| O'Brien, TJ | 1 |
| Dibué, M | 1 |
| Kamp, MA | 1 |
| Neumaier, F | 1 |
| Steiger, HJ | 1 |
| Hänggi, D | 1 |
| Hescheler, J | 1 |
| Schneider, T | 1 |
| Dawson, EA | 1 |
| Gupta, PK | 1 |
| Madden, CJ | 1 |
| Pacheco, J | 1 |
| Olson, DM | 1 |
| Dupuis, M | 1 |
| van Rijckevorsel, K | 1 |
| Evrard, F | 1 |
| Dubuisson, N | 1 |
| Dupuis, F | 1 |
| Van Robays, P | 1 |
| Aurlien, D | 1 |
| Larsen, JP | 1 |
| Gjerstad, L | 1 |
| Taubøll, E | 1 |
| Tomson, T | 1 |
| Hirsch, LJ | 1 |
| Bester, N | 1 |
| Hammer, A | 1 |
| Irizarry, M | 1 |
| Ishihara, L | 1 |
| Krishen, A | 1 |
| Spaulding, T | 1 |
| Wamil, A | 1 |
| Leadbetter, R | 1 |
| Ruiz Ginés, MA | 1 |
| García García, S | 1 |
| Ruiz Ginés, JA | 1 |
| Tze Kiong, E | 1 |
| Fernández Rodríguez, E | 1 |
| Leestma, JE | 1 |
| Annegers, JF | 1 |
| Brodie, MJ | 1 |
| Brown, S | 1 |
| Schraeder, P | 1 |
| Siscovick, D | 1 |
| Wannamaker, BB | 1 |
| Tennis, PS | 1 |
| Cierpial, MA | 1 |
| Earl, NL | 1 |
| Kloster, R | 1 |
| Børresen, HC | 1 |
| Hoff-Olsen, P | 1 |
| Wong, IC | 1 |
| Mawer, GE | 1 |
| Sander, JW | 1 |
1 review available for lamotrigine and Death, Sudden
| Article | Year |
|---|---|
Takotsubo syndrome (TKS): a possible mechanism of sudden unexplained death in epilepsy (SUDEP).
Topics: Adrenergic beta-1 Receptor Antagonists; Anticonvulsants; Aspirin; Bisoprolol; Death, Sudden; Epileps | 2012 |
10 other studies available for lamotrigine and Death, Sudden
| Article | Year |
|---|---|
Rare sudden unexpected death in epilepsy SCN5A variants cause changes in channel function implicating cardiac arrhythmia as a cause of death.
Topics: Anticonvulsants; Arrhythmias, Cardiac; Cause of Death; Death, Sudden; Death, Sudden, Cardiac; Epilep | 2022 |
Risk of sudden unexpected death in epilepsy (SUDEP) with lamotrigine and other sodium channel-modulating antiseizure medications.
Topics: Anticonvulsants; Case-Control Studies; Death, Sudden; Epilepsy; Humans; Lamotrigine; Retrospective S | 2023 |
Cardiac phenomena during kainic-acid induced epilepsy and lamotrigine antiepileptic therapy.
Topics: Animals; Anticonvulsants; Death, Sudden; Electrocardiography; Epilepsy; Kainic Acid; Lamotrigine; Mi | 2014 |
Arrhythmias in the epilepsy monitoring unit: watching for sudden unexpected death in epilepsy.
Topics: Adolescent; Arrhythmias, Cardiac; Athletic Injuries; Brain Concussion; Cause of Death; Death, Sudden | 2015 |
Increased risk of sudden unexpected death in epilepsy in females using lamotrigine: a nested, case-control study.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Case-Control Studies; Death, Sudden; Epilepsy; Female; Hum | 2012 |
Sudden unexpected death in epilepsy in lamotrigine randomized-controlled trials.
Topics: Adult; Anticonvulsants; Confidence Intervals; Death, Sudden; Epilepsy; Female; Humans; Lamotrigine; | 2013 |
[Symptomatic secondary hyponatraemia due to combined treatment anticonvulsant and antidepressant: risk of sudden death in epilepsy?].
Topics: Adult; Anticonvulsants; Antidepressive Agents; Carbamazepine; Cyclohexanols; Death, Sudden; Drug Int | 2007 |
Sudden unexplained death in epilepsy: observations from a large clinical development program.
Topics: Adolescent; Adult; Anticonvulsants; Cause of Death; Child; Clinical Trials as Topic; Cohort Studies; | 1997 |
Sudden death in two patients with epilepsy and the syndrome of inappropriate antidiuretic hormone secretion (SIADH).
Topics: Adolescent; Adult; Anticonvulsants; Autopsy; Carbamazepine; Death, Sudden; Epilepsy; gamma-Aminobuty | 1998 |
Adverse event monitoring in lamotrigine patients: a pharmacoepidemiologic study in the United Kingdom.
Topics: Acetates; Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Amines; Anticonvulsants; | 2001 |