lamotrigine has been researched along with Death, Sudden, Cardiac in 6 studies
Death, Sudden, Cardiac: Unexpected rapid natural death due to cardiovascular collapse within one hour of initial symptoms. It is usually caused by the worsening of existing heart diseases. The sudden onset of symptoms, such as CHEST PAIN and CARDIAC ARRHYTHMIAS, particularly VENTRICULAR TACHYCARDIA, can lead to the loss of consciousness and cardiac arrest followed by biological death. (from Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine, 7th ed., 2005)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lamotrigine (LTG) has recently been shown to inhibit the cardiac rapid delayed rectifier potassium ion current (Ikr)." | 5.34 | Lamotrigine in idiopathic epilepsy - increased risk of cardiac death? ( Aurlien, D; Gjerstad, L; Taubøll, E, 2007) |
| "There is insufficient evidence to support or refute that lamotrigine is associated with sudden death or ECG changes in people with or without epilepsy as compared to antiseizure medication or placebo, due to the high risk of bias in most studies and low precision and inconsistency in the reported results." | 5.22 | Sudden Death and Cardiac Arrythmia With Lamotrigine: A Rapid Systematic Review. ( Bunschoten, JW; Devinsky, O; French, JA; Husein, N; Keezer, MR; Sander, JW; Thijs, RD, 2022) |
| "Cardiac arrhythmia has been suggested as a cause of death in some patients with SUDEP." | 1.72 | Rare sudden unexpected death in epilepsy SCN5A variants cause changes in channel function implicating cardiac arrhythmia as a cause of death. ( Bagnall, RD; Berkovic, SF; Reid, CA; Scheffer, IE; Semsarian, C; Soh, MS, 2022) |
| "Lamotrigine (LTG) has recently been shown to inhibit the cardiac rapid delayed rectifier potassium ion current (Ikr)." | 1.34 | Lamotrigine in idiopathic epilepsy - increased risk of cardiac death? ( Aurlien, D; Gjerstad, L; Taubøll, E, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Bunschoten, JW | 1 |
| Husein, N | 1 |
| Devinsky, O | 1 |
| French, JA | 1 |
| Sander, JW | 1 |
| Thijs, RD | 1 |
| Keezer, MR | 1 |
| Soh, MS | 1 |
| Bagnall, RD | 1 |
| Semsarian, C | 1 |
| Scheffer, IE | 1 |
| Berkovic, SF | 1 |
| Reid, CA | 1 |
| Aurlien, D | 3 |
| Leren, TP | 1 |
| Taubøll, E | 3 |
| Gjerstad, L | 3 |
| VanLandingham, KE | 1 |
| Dixon, RM | 1 |
1 review available for lamotrigine and Death, Sudden, Cardiac
| Article | Year |
|---|---|
Sudden Death and Cardiac Arrythmia With Lamotrigine: A Rapid Systematic Review.
Topics: Anticonvulsants; Arrhythmias, Cardiac; Death, Sudden, Cardiac; Epilepsy; Humans; Lamotrigine; Risk F | 2022 |
5 other studies available for lamotrigine and Death, Sudden, Cardiac
| Article | Year |
|---|---|
Rare sudden unexpected death in epilepsy SCN5A variants cause changes in channel function implicating cardiac arrhythmia as a cause of death.
Topics: Anticonvulsants; Arrhythmias, Cardiac; Cause of Death; Death, Sudden; Death, Sudden, Cardiac; Epilep | 2022 |
New SCN5A mutation in a SUDEP victim with idiopathic epilepsy.
Topics: Adolescent; Anticonvulsants; Base Sequence; Death, Sudden, Cardiac; Epilepsy; Female; Humans; Lamotr | 2009 |
Lamotrigine in idiopathic epilepsy - increased risk of cardiac death?
Topics: Adolescent; Adult; Anticonvulsants; Death, Sudden, Cardiac; Epilepsy; Female; Humans; Lamotrigine; T | 2007 |
Lamotrigine in idiopathic epilepsy - increased risk of cardiac death.
Topics: Adolescent; Adult; Anticonvulsants; Arrhythmias, Cardiac; Death, Sudden, Cardiac; Dose-Response Rela | 2007 |
An insufficient effect of lamotrigine leading to fatal seizures.
Topics: Acidosis; Age Factors; Anticonvulsants; Apnea; Arrhythmias, Cardiac; Death, Sudden, Cardiac; Dose-Re | 2008 |