lamotrigine has been researched along with Cryptogenic Infantile Spasms in 14 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Vigabatrin is a specific and irreversible inhibitor of the enzyme gamma-amino-butyric-acid (GABA) transferase." | 6.39 | [Vigabatrin and lamotrigin: experiences with 2 new anticonvulsants in the Swiss epilepsy clinic]. ( Krämer, G; Vogt, H, 1995) |
| " The point estimates of carbamazepine and lamotrigine efficacy showed their superiority with respect to all comparator antiepileptic drugs for the treatment of newly diagnosed focal epilepsy." | 4.98 | Comparative efficacy of antiepileptic drugs in children and adolescents: A network meta-analysis. ( Crescioli, G; De Masi, S; Guerrini, R; Ilvento, L; Lucenteforte, E; McGreevy, KS; Mugelli, A; Pugi, A; Rosati, A; Virgili, G, 2018) |
| " The mainstay of treatment is with multiple anti-seizure medications (ASMs); however, the ASMs themselves can be associated with psychobehavioural adverse events, and effects (negative or positive) on cognition and sleep." | 2.82 | Psychobehavioural and Cognitive Adverse Events of Anti-Seizure Medications for the Treatment of Developmental and Epileptic Encephalopathies. ( Schubert-Bast, S; Strzelczyk, A, 2022) |
| "Lamotrigine is a useful and well tolerated drug for partial seizures and infantile spasms in infants <1 year of age." | 2.70 | Efficacy, tolerability, and kinetics of lamotrigine in infants. ( Fayad, M; Hussein, R; Kazma, A; Koleilat, M; Mikati, MA; Mounla, N; Yunis, K, 2002) |
| "Vigabatrin has shown promise in treating IS patients, particularly those with tuberous sclerosis." | 2.42 | Pharmacologic treatment of the catastrophic epilepsies. ( Conry, JA, 2004) |
| "Vigabatrin is a specific and irreversible inhibitor of the enzyme gamma-amino-butyric-acid (GABA) transferase." | 2.39 | [Vigabatrin and lamotrigin: experiences with 2 new anticonvulsants in the Swiss epilepsy clinic]. ( Krämer, G; Vogt, H, 1995) |
| "However, seizures are not typical and the majority of them were seizure-free." | 1.51 | A 16q22.2-q23.1 deletion identified in a male infant with West syndrome. ( Goji, A; Imoto, I; Ito, H; Kagami, S; Kohmoto, T; Mori, K; Mori, T; Toda, Y, 2019) |
| "On VPA 1000 mg/d, the seizure frequency decreased significantly." | 1.37 | Valproate treatment after liver transplant in a patient with Lennox-Gastaut syndrome. ( Crespel, A; Gelisse, P; Genton, P; Pageaux, GP; Velizarova, R, 2011) |
| "Three infants affected with symptomatic West syndrome (WS), unresponsive to gamma-vinyl-GABA and to ACTH (first line drugs for WS), were rapidly cured with very small doses of lamotrigine (LTG)." | 1.31 | Low-dose lamotrigine in West syndrome. ( Cianchetti, C; Coppola, G; Pascotto, A; Pruna, D, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (21.43) | 18.2507 |
| 2000's | 5 (35.71) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 2 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Strzelczyk, A | 1 |
| Schubert-Bast, S | 1 |
| Treadwell, JR | 1 |
| Kessler, SK | 1 |
| Wu, M | 1 |
| Abend, NS | 1 |
| Massey, SL | 1 |
| Tsou, AY | 1 |
| Rosati, A | 1 |
| Ilvento, L | 1 |
| Lucenteforte, E | 1 |
| Pugi, A | 1 |
| Crescioli, G | 1 |
| McGreevy, KS | 1 |
| Virgili, G | 1 |
| Mugelli, A | 1 |
| De Masi, S | 1 |
| Guerrini, R | 1 |
| Mori, T | 1 |
| Goji, A | 1 |
| Toda, Y | 1 |
| Ito, H | 1 |
| Mori, K | 1 |
| Kohmoto, T | 1 |
| Imoto, I | 1 |
| Kagami, S | 1 |
| Okumura, A | 1 |
| Arai, E | 1 |
| Kitamura, Y | 1 |
| Abe, S | 1 |
| Ikeno, M | 1 |
| Fujimaki, T | 1 |
| Yamamoto, T | 1 |
| Shimizu, T | 1 |
| Velizarova, R | 1 |
| Gelisse, P | 1 |
| Pageaux, GP | 1 |
| Genton, P | 1 |
| Crespel, A | 1 |
| Cianchetti, C | 1 |
| Pruna, D | 1 |
| Coppola, G | 1 |
| Pascotto, A | 1 |
| Conry, JA | 1 |
| Vogt, H | 1 |
| Krämer, G | 1 |
| Veggiotti, P | 1 |
| Cieuta, C | 1 |
| Rex, E | 1 |
| Dulac, O | 2 |
| Pellock, JM | 1 |
| Appleton, R | 1 |
| Franz, DN | 1 |
| Tudor, C | 1 |
| Leonard, J | 1 |
| Egelhoff, JC | 1 |
| Byars, A | 1 |
| Valerius, K | 1 |
| Sethuraman, G | 1 |
| Chiron, C | 1 |
| Mikati, MA | 1 |
| Fayad, M | 1 |
| Koleilat, M | 1 |
| Mounla, N | 1 |
| Hussein, R | 1 |
| Kazma, A | 1 |
| Yunis, K | 1 |
7 reviews available for lamotrigine and Cryptogenic Infantile Spasms
| Article | Year |
|---|---|
Psychobehavioural and Cognitive Adverse Events of Anti-Seizure Medications for the Treatment of Developmental and Epileptic Encephalopathies.
Topics: Autism Spectrum Disorder; Bromides; Cannabidiol; Clobazam; Cognition; Ethosuximide; Everolimus; Felb | 2022 |
Pharmacologic and Dietary Treatments for Epilepsies in Children Aged 1-36 Months: A Systematic Review.
Topics: Anticonvulsants; Child; Diet, Ketogenic; Epilepsy; Humans; Infant; Infant, Newborn; Lamotrigine; Lev | 2023 |
Comparative efficacy of antiepileptic drugs in children and adolescents: A network meta-analysis.
Topics: Adolescent; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anticonvulsants; Carbamazepine; Ch | 2018 |
Pharmacologic treatment of the catastrophic epilepsies.
Topics: Anticonvulsants; Child, Preschool; Epilepsies, Myoclonic; Epilepsy; Fructose; Humans; Infant; Isoxaz | 2004 |
[Vigabatrin and lamotrigin: experiences with 2 new anticonvulsants in the Swiss epilepsy clinic].
Topics: 4-Aminobutyrate Transaminase; Adult; Anticonvulsants; Child; Drug Therapy, Combination; Epilepsies, | 1995 |
Use of new antiepileptic drugs in the treatment of childhood epilepsy.
Topics: Acetates; Adult; Age Factors; Amines; Anticonvulsants; Child; Clinical Trials as Topic; Cyclohexanec | 1999 |
Drug therapy for West's syndrome.
Topics: Anticonvulsants; Humans; Infant; Infant, Newborn; Lamotrigine; Spasms, Infantile; Steroids; Triazine | 2002 |
2 trials available for lamotrigine and Cryptogenic Infantile Spasms
| Article | Year |
|---|---|
Lamotrigine therapy of epilepsy in tuberous sclerosis.
Topics: Adolescent; Adult; Age of Onset; Anticonvulsants; Child; Child, Preschool; Dose-Response Relationshi | 2001 |
Efficacy, tolerability, and kinetics of lamotrigine in infants.
Topics: Age Factors; Anticonvulsants; Epilepsies, Partial; Humans; Infant; Infant, Newborn; Lamotrigine; Lin | 2002 |
5 other studies available for lamotrigine and Cryptogenic Infantile Spasms
| Article | Year |
|---|---|
A 16q22.2-q23.1 deletion identified in a male infant with West syndrome.
Topics: Anticonvulsants; Chromosomes, Human, Pair 16; Epilepsy; Humans; Infant; Intellectual Disability; Lam | 2019 |
Epilepsy phenotypes in siblings with Norrie disease.
Topics: Anticonvulsants; Blindness; Chromosomes, Human, X; Electroencephalography; Epilepsy; Eye Proteins; G | 2015 |
Valproate treatment after liver transplant in a patient with Lennox-Gastaut syndrome.
Topics: Anticonvulsants; Chemical and Drug Induced Liver Injury; Electroencephalography; Female; Fructose; H | 2011 |
Low-dose lamotrigine in West syndrome.
Topics: Adrenocorticotropic Hormone; Anticonvulsants; Child, Preschool; Electroencephalography; Female; Huma | 2002 |
Lamotrigine in infantile spasms.
Topics: Anticonvulsants; Child; Child, Preschool; Female; Humans; Infant; Lamotrigine; Male; Spasms, Infanti | 1994 |