Page last updated: 2024-10-30

lamotrigine and Convulsive Generalized Seizure Disorder

lamotrigine has been researched along with Convulsive Generalized Seizure Disorder in 97 studies

Research Excerpts

ExcerptRelevanceReference
"56 G > A rs17183814 on the response to lamotrigine monotherapy in patients with focal epilepsy in Herzegovina area, Bosnia and Herzegovina."7.91Lack of association of SCN2A rs17183814 polymorphism with the efficacy of lamotrigine monotherapy in patients with focal epilepsy from Herzegovina area, Bosnia and Herzegovina. ( Basic, S; Bozina, N; Markovic, I; Pejanovic-Skobic, N, 2019)
"Lamotrigine (LTG) has shown to confer broad-spectrum, well-tolerated control of epilepsy."7.75Efficacy and safety of lamotrigine monotherapy in children and adolescents with epilepsy. ( Hardison, HH; Khurana, DS; Kothare, SV; Legido, A; Marks, HG; Melvin, JJ; Piñol-Ripoll, G; Valencia, I, 2009)
"To describe lamotrigine intoxication paradoxically producing status epilepticus in an adult with localization-related epilepsy."7.74Lamotrigine intoxication provoking status epilepticus in an adult with localization-related epilepsy. ( Dinnerstein, E; Jobst, BC; Williamson, PD, 2007)
"A retrospective survey was carried out of add-on treatment with lamotrigine (LTG) and vigabatrin (GVG) in 109 children with severe epilepsy, treated between 1987 and 1994, identified from a total population of 300 patients seen annually, in a tertiary referral outpatient clinic in Cardiff, Wales."7.69A survey of lamotrigine and vigabatrin treatment in children with severe epilepsy. ( Gordon, GS; Schapel, GJ; Wallace, SJ, 1997)
"Fifty-two children with intractable epilepsy received lamotrigine as add-on therapy on a compassionate basis."7.69[Treatment of childhood epilepsy with lamotrigine. An evaluation of efficacy in different types of epilepsy]. ( Sommer, B; Uldall, PV, 1996)
"Lamotrigine is a relatively new AED which is licensed in many countries for use as an initial monotherapy."6.43Lamotrigine versus carbamazepine monotherapy for epilepsy. ( Gamble, CL; Marson, AG; Williamson, PR, 2006)
"Patients with generalized epilepsy (p = 0."5.31A pharmacoepidemiologic study of factors influencing the outcome of treatment with lamotrigine in chronic epilepsy. ( Lhatoo, SD; Mawer, GE; Sander, JW; Wong, IC, 2001)
"Seventy-one patients had partial epilepsy and 21 had primary generalized epilepsy."5.29[Lamotrigine treatment of 92 patients with intractable epilepsy]. ( Dam, M; Gram, L; Karlsborg, M, 1996)
"To explore the efficacy and safety of the combined therapy of valproic acid (VPA) and lamotrigine (LTG) for various types of epilepsy."5.16[Efficacy and safety of the combined therapy of valproic acid and lamotrigine for epileptics]. ( Hu, Q; Kang, HC; Li, X; Liu, XY; Liu, ZG; Wang, M; Xu, F; Zeng, Z; Zhu, SQ, 2012)
"56 G > A rs17183814 on the response to lamotrigine monotherapy in patients with focal epilepsy in Herzegovina area, Bosnia and Herzegovina."3.91Lack of association of SCN2A rs17183814 polymorphism with the efficacy of lamotrigine monotherapy in patients with focal epilepsy from Herzegovina area, Bosnia and Herzegovina. ( Basic, S; Bozina, N; Markovic, I; Pejanovic-Skobic, N, 2019)
"Lamotrigine (LTG) has shown to confer broad-spectrum, well-tolerated control of epilepsy."3.75Efficacy and safety of lamotrigine monotherapy in children and adolescents with epilepsy. ( Hardison, HH; Khurana, DS; Kothare, SV; Legido, A; Marks, HG; Melvin, JJ; Piñol-Ripoll, G; Valencia, I, 2009)
" It identifies lamotrigine as a cost-effective alternative to carbamazepine for the treatment of focal epilepsies, but confirms valproate as the most effective drug for the treatment of generalized or unclassified epilepsy."3.74Choosing a first drug treatment for epilepsy after SANAD: randomized controlled trials, systematic reviews, guidelines and treating patients. ( Chadwick, D; Marson, T, 2007)
"To describe lamotrigine intoxication paradoxically producing status epilepticus in an adult with localization-related epilepsy."3.74Lamotrigine intoxication provoking status epilepticus in an adult with localization-related epilepsy. ( Dinnerstein, E; Jobst, BC; Williamson, PD, 2007)
"During her first pregnancy, a 37-year-old woman with idiopathic generalised epilepsy that was adequately controlled with lamotrigine experienced a series of epileptic seizures following an elective caesarean section."3.73[Epileptic seizures during childbirth in a patient with idiopathic generalised epilepsy]. ( Bloem, BR; Renier, WO; Voermans, NC; Zwarts, MJ, 2005)
"Reversible neurotoxic symptoms were observed in three adult patients with absence status epilepticus on lamotrigine (LTG) therapy after administration of an IV bolus followed by oral valproic acid (VPA)."3.72Neurotoxicity following addition of intravenous valproate to lamotrigine therapy. ( Burneo, JG; Faught, E; Knowlton, RC; Kuzniecky, RI; Lawn, N; Limdi, N; Mendez, M; Prasad, A; Welty, TE, 2003)
"A retrospective survey was carried out of add-on treatment with lamotrigine (LTG) and vigabatrin (GVG) in 109 children with severe epilepsy, treated between 1987 and 1994, identified from a total population of 300 patients seen annually, in a tertiary referral outpatient clinic in Cardiff, Wales."3.69A survey of lamotrigine and vigabatrin treatment in children with severe epilepsy. ( Gordon, GS; Schapel, GJ; Wallace, SJ, 1997)
"Fifty-two children with intractable epilepsy received lamotrigine as add-on therapy on a compassionate basis."3.69[Treatment of childhood epilepsy with lamotrigine. An evaluation of efficacy in different types of epilepsy]. ( Sommer, B; Uldall, PV, 1996)
" The mean lamotrigine dosage was 211."2.72Regional effects of lamotrigine on cerebral glucose metabolism in idiopathic generalized epilepsy. ( Hong, SB; Joo, EY; Tae, WS, 2006)
"Lamotrigine has demonstrated efficacy from published randomized clinical trials for childhood partial seizures, absence seizures, and for the generalized seizures associated with Lennox-Gastaut syndrome."2.72Lamotrigine adjunctive therapy among children and adolescents with primary generalized tonic-clonic seizures. ( Hammer, AE; Kerls, SP; Messenheimer, JA; Trevathan, E; Vuong, A, 2006)
" The rate of patients discontinuing treatment due to adverse events or a lack of efficacy was 19% with CBZ compared to 9% with LTG (not statistically different)."2.71The LAM-SAFE Study: lamotrigine versus carbamazepine or valproic acid in newly diagnosed focal and generalised epilepsies in adolescents and adults. ( Bergmann, L; Kurlemann, G; Schmitz, B; Siemes, H; Steinhoff, BJ; Ueberall, MA, 2005)
" The LTG dosage was individualized in an open phase preceding the placebo/treatment phase."2.69The efficacy of lamotrigine in children and adolescents with refractory generalized epilepsy: a randomized, double-blind, crossover study. ( Eriksson, AS; Hoppu, K; Nergårdh, A, 1998)
"Epilepsy is a common neurological condition with a worldwide prevalence of around 1%."2.55Antiepileptic drug monotherapy for epilepsy: a network meta-analysis of individual participant data. ( Marson, AG; Nevitt, SJ; Sudell, M; Tudur Smith, C; Weston, J, 2017)
"Epilepsy is a common neurological condition with a worldwide prevalence of around 1%."2.55Antiepileptic drug monotherapy for epilepsy: a network meta-analysis of individual participant data. ( Marson, AG; Nevitt, SJ; Sudell, M; Tudur Smith, C; Weston, J, 2017)
"Lamotrigine was significantly less likely to be withdrawn than carbamazepine but the results for time to first seizure suggested that carbamazepine may be superior in terms of seizure control."2.53Lamotrigine versus carbamazepine monotherapy for epilepsy: an individual participant data review. ( Marson, AG; Nolan, SJ; Tudur Smith, C; Weston, J, 2016)
"Occurrence of generalized tonic-clonic seizures (GTCS) is one of the most important risk factors of seizure-related complications and comorbidities in patients with epilepsy."2.50Pharmacotherapy for tonic-clonic seizures. ( Rheims, S; Ryvlin, P, 2014)
"Juvenile myoclonic epilepsy is a common idiopathic generalized epileptic syndrome that includes generalized myoclonic seizures and commonly generalized tonic-clonic and generalized absence seizures."2.45The first line of therapy in a girl with juvenile myoclonic epilepsy: should it be valproate or a new agent? ( Abou-Khalil, B; Montouris, G, 2009)
"Lamotrigine is a relatively new AED which is licensed in many countries for use as an initial monotherapy."2.43Lamotrigine versus carbamazepine monotherapy for epilepsy. ( Gamble, CL; Marson, AG; Williamson, PR, 2006)
" Dosing in generalized seizures is similar to that for partial seizures."2.40Lamotrigine in absence and primary generalized epilepsies. ( Holmes, GL; Mikati, MA, 1997)
"All patients with a diagnosis of IGE, focal epilepsy, or SGE, who received either LTG or LEV, were recruited at the outpatient epilepsy clinic at Shiraz University of Medical Sciences, Shiraz, Iran from 2008 until 2020."1.72Rational therapy with lamotrigine or levetiracetam: Which one to select? ( Asadi-Pooya, AA; Farazdaghi, M, 2022)
"Under lamotrigine, seizure aggravation was observed in 15 patients (two patients during levetiracetam, one patient during zonisamide, none during phenobarbital and valproic acid)."1.62Risk factors of paradoxical reactions to anti-seizure medication in genetic generalized epilepsy. ( Beier, CP; Gesche, J; Hjalgrim, H; Rubboli, G, 2021)
"For those with focal epilepsy, levetiracetam, oxcarbazepine, or lamotrigine were the most popular selections."1.56Treatment of epilepsy in adults: Expert opinion in South Korea. ( Byun, JI; Cho, YW; Kang, KW; Kim, D; Kim, DW; Kim, JM; Kim, KT; Lee, ST; No, YJ; Seo, JG; Yang, KI, 2020)
"Topiramate was more likely prescribed for those with comorbid headache or migraine (incident: 335 of 1251 [26."1.51Antiepileptic Drug Treatment Patterns in Women of Childbearing Age With Epilepsy. ( Faught, E; Fishman, J; Kalilani, L; Kim, H; Thurman, DJ, 2019)
"Idiopathic generalized epilepsy (IGE) was diagnosed in 85 cases, cryptogenic focal epilepsy in 107 cases, symptomatic focal epilepsy in 51 cases, unclassified epilepsy in 32 cases."1.38[Idiopathic generalized epilepsy in young women: choise of treatment strategy]. ( Kotov, AS, 2012)
"We describe a case of oral hairy leukoplakia that presented with an atypical appearance in a patient on long-term anticonvulsant treatment with an aromatic antiepileptic, lamotrigine."1.37Oral hairy leukoplakia in a patient on long-term anticonvulsant treatment with lamotrigine. ( Gordins, P; Sloan, P; Spickett, GP; Staines, KS, 2011)
"Epilepsy was most common among those with maternal deletions and unknown subtypes, with catastrophic epilepsies present in only these two subtypes."1.35Epilepsy in Angelman syndrome: a questionnaire-based assessment of the natural history and current treatment options. ( Braun, EK; Bruno, P; Conant, KD; Nespeca, MP; Said, RR; Thibert, RL; Thiele, EA, 2009)
" The dosage schedule was: 5 mg every day or every second day for 14 days, increased by 5 mg every 14th day to 25 mg a day."1.33Lamotrigine-induced rash--worth a rechallenge. ( Dam, M; P-Codrea Tigaran, S; Sidenius, P, 2005)
"Lamotrigine is a useful add-on therapy in treating children with epilepsy."1.33The use of lamotrigine, vigabatrin and gabapentin as add-on therapy in intractable epilepsy of childhood. ( Keegan, MB; Madden, D; McDonald, DG; McMenamin, JB; Najam, Y; Whooley, M, 2005)
"A 25-year-old girl with mild mental retardation had a 6-year history of absence seizures, with occasional head drop."1.31Mild generalized epilepsy and developmental disorder associated with large inv dup(15). ( Canevini, MP; Canger, R; Cavani, S; Chifari, R; Elia, M; Guerrini, R; Pierluigi, M; Sgrò, V, 2002)
"Overall, 45% were seizure free, 44% with focal epilepsy and 36% with generalized epilepsy."1.31Lamotrigine monotherapy in children. ( Barron, TF; Hoban, TF; Hunt, SL; Price, ML, 2000)
"Idiopathic generalized epilepsy presenting with hemiconvulsive seizures has not, to our knowledge, been previously described."1.31Idiopathic generalized epilepsy presenting with hemiconvulsive seizures. ( Kiley, MA; Sander, JW; Smith, SJ, 2000)
"Patients with generalized epilepsy (p = 0."1.31A pharmacoepidemiologic study of factors influencing the outcome of treatment with lamotrigine in chronic epilepsy. ( Lhatoo, SD; Mawer, GE; Sander, JW; Wong, IC, 2001)
" The LTG dosage was increased step by step until clinical response or side effects were observed."1.30No increase in carbamazepine-10,11-epoxide during addition of lamotrigine treatment in children. ( Boreus, LO; Eriksson, AS, 1997)
"Of 12 patients with refractory childhood absence epilepsy, 9 became seizure free; in one child with absences with eyelid myoclonia, absence frequency was reduced > 50%; in 2 children with absences with a mild atonic component, seizure reduction was only transient."1.30Efficacy of lamotrigine in idiopathic generalized epilepsy syndromes: a video-EEG-controlled, open study. ( de Saint-Martin, A; Gericke, CA; Hirsch, E; Marescaux, C; Picard, F; Strumia, S, 1999)
"In severe myoclonic epilepsy of infancy (SME), multiple drug-resistant focal and generalized seizure types occur."1.30Lamotrigine and seizure aggravation in severe myoclonic epilepsy. ( Belmonte, A; Dravet, C; Dulac, O; Genton, P; Guerrini, R; Kaminska, A, 1998)
"Lamotrigine was well tolerated."1.29Lamotrigine as an add-on drug in typical absence seizures. ( Ferrie, CD; Knott, C; Panayiotopoulos, CP; Robinson, RO, 1995)
"Seventy-one patients had partial epilepsy and 21 had primary generalized epilepsy."1.29[Lamotrigine treatment of 92 patients with intractable epilepsy]. ( Dam, M; Gram, L; Karlsborg, M, 1996)
"Lamotrigine is a very useful antiepileptic medication of a "broad spectrum' nature being effective in primary generalized epilepsy and partial seizures as add-on therapy."1.29Lamotrigine: clinical experience in 200 patients with epilepsy with follow-up to four years. ( Buchanan, N, 1996)

Research

Studies (97)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's31 (31.96)18.2507
2000's39 (40.21)29.6817
2010's19 (19.59)24.3611
2020's8 (8.25)2.80

Authors

AuthorsStudies
Asadi-Pooya, AA1
Farazdaghi, M1
Hochbaum, M1
Kienitz, R1
Rosenow, F1
Schulz, J1
Habermehl, L1
Langenbruch, L1
Kovac, S1
Knake, S1
von Podewils, F1
von Brauchitsch, S1
Hamacher, M1
Strzelczyk, A1
Willems, LM1
Bleakley, LE1
McKenzie, CE1
Reid, CA1
Brigo, F1
Striano, P2
Belcastro, V1
Pejanovic-Skobic, N1
Markovic, I1
Bozina, N1
Basic, S1
Byun, JI1
Kim, DW1
Kim, KT1
Yang, KI1
Lee, ST1
Seo, JG1
No, YJ1
Kang, KW1
Kim, D1
Kim, JM1
Cho, YW1
Wolking, S1
Schulz, H1
Nies, AT1
McCormack, M1
Schaeffeler, E1
Auce, P1
Avbersek, A1
Becker, F1
Klein, KM1
Krenn, M1
Møller, RS2
Nikanorova, M1
Weckhuysen, S1
Consortium, E1
Cavalleri, GL1
Delanty, N1
Depondt, C1
Johnson, MR1
Koeleman, BP1
Kunz, WS2
Marson, AG8
Sander, JW3
Sills, GJ1
Zara, F1
Zimprich, F1
Weber, YG2
Krause, R1
Sisodiya, S1
Schwab, M1
Sander, T2
Lerche, H2
Gesche, J3
Hjalgrim, H4
Rubboli, G3
Beier, CP3
Coppola, G1
Piccorossi, A1
Operto, FF1
Verrotti, A1
Nevitt, SJ3
Sudell, M2
Weston, J4
Tudur Smith, C5
Tang, L1
Ge, L1
Wu, W1
Yang, X1
Rui, P1
Wu, Y1
Yu, W1
Wang, X1
Wu, D1
Chen, L1
Ji, F1
Si, Y1
Sun, H1
Kim, H1
Faught, E2
Thurman, DJ1
Fishman, J1
Kalilani, L1
Bonnett, LJ1
Smith, D1
Williamson, PR3
Chadwick, D3
Rheims, S1
Ryvlin, P1
El-Farahaty, RM1
El-Mitwalli, A1
Azzam, H1
Wasel, Y1
Elrakhawy, MM1
Hasaneen, BM1
Nolan, SJ1
Valencia, I1
Piñol-Ripoll, G1
Khurana, DS1
Hardison, HH1
Kothare, SV1
Melvin, JJ1
Marks, HG1
Legido, A1
Clemens, B2
Piros, P2
Bessenyei, M2
Tóth, M1
Hollódy, K2
Kondákor, I1
Moeller, JJ1
Rahey, SR1
Sadler, RM1
Taillia, H1
Alla, P1
Fournier, B1
Bounolleau, P1
Ouologem, M1
Ricard, D1
Sallansonnet-Froment, M1
de Greslan, T1
Renard, JL1
Thibert, RL1
Conant, KD1
Braun, EK1
Bruno, P1
Said, RR1
Nespeca, MP1
Thiele, EA1
Montouris, G1
Abou-Khalil, B4
Sepić-Grahovac, D1
Ruzić Barsić, A1
Ruzić, K1
Grahovac, T1
Dadić-Hero, E1
Musiek, ES1
Anderson, CT1
Dahodwala, NA1
Pollard, JR1
Gordins, P1
Sloan, P1
Spickett, GP1
Staines, KS1
Kang, HC1
Hu, Q1
Liu, XY1
Xu, F1
Li, X1
Liu, ZG1
Zeng, Z1
Wang, M1
Zhu, SQ1
Kotov, AS1
Klitten, LL1
Trucks, H1
Muhle, H1
Mefford, HC1
Franke, A1
Kautza, M1
Wolf, P1
Dennig, D1
Schreiber, S1
Rückert, IM1
Wichmann, HE1
Ernst, JP1
Schurmann, C1
Grabe, HJ1
Tommerup, N1
Stephani, U1
Helbig, I1
Chifari, R1
Guerrini, R2
Pierluigi, M1
Cavani, S1
Sgrò, V1
Elia, M1
Canger, R1
Canevini, MP1
Trinka, E1
Dilitz, E1
Unterberger, I1
Luef, G1
Deisenhammer, F1
Niedermüller, U1
Thaler, C1
Bauer, G1
Bourgeois, BF1
Burneo, JG1
Limdi, N1
Kuzniecky, RI1
Knowlton, RC1
Mendez, M1
Lawn, N1
Welty, TE1
Prasad, A1
Smith, J1
Fernando, T1
McGrath, N1
Ameratunga, R1
French, JA4
Kanner, AM3
Bautista, J3
Browne, T3
Harden, CL3
Theodore, WH3
Bazil, C3
Stern, J3
Schachter, SC3
Bergen, D3
Hirtz, D3
Montouris, GD3
Nespeca, M3
Gidal, B3
Marks, WJ3
Turk, WR3
Fischer, JH3
Bourgeois, B3
Wilner, A3
Faught, RE3
Sachdeo, RC3
Beydoun, A3
Glauser, TA3
Kilfoyle, DH1
Anderson, NE1
Wallis, WE1
Nicholls, DW1
McDonald, DG1
Najam, Y1
Keegan, MB1
Whooley, M1
Madden, D1
McMenamin, JB1
P-Codrea Tigaran, S1
Sidenius, P1
Dam, M2
Voermans, NC1
Zwarts, MJ1
Renier, WO1
Bloem, BR1
Chappell, B1
Crawford, P1
Steinhoff, BJ1
Ueberall, MA1
Siemes, H1
Kurlemann, G1
Schmitz, B2
Bergmann, L2
Benbadis, SR1
Gamble, CL1
Joo, EY2
Hong, SB2
Tae, WS2
Han, SJ1
Seo, DW1
Lee, KH1
Lee, MH1
Kryscio, RJ1
Trevathan, E1
Kerls, SP1
Hammer, AE1
Vuong, A1
Messenheimer, JA1
Unay, B1
Akin, R1
Sarici, SU1
Gok, F1
Kurt, I1
Gokcay, E1
Al-Kharusi, AM1
Alwaidh, M1
Appleton, R1
Baker, GA1
Chadwick, DW1
Cramp, C1
Cockerell, OC1
Cooper, PN1
Doughty, J1
Eaton, B1
Gamble, C1
Goulding, PJ1
Howell, SJ1
Hughes, A1
Jackson, M1
Jacoby, A1
Kellett, M1
Lawson, GR1
Leach, JP1
Nicolaides, P1
Roberts, R1
Shackley, P1
Shen, J1
Smith, DF1
Smith, PE1
Smith, CT1
Vanoli, A1
Marson, T1
Dinnerstein, E1
Jobst, BC1
Williamson, PD1
Bakunts, GO1
Burd, GS1
Vaĭntrub, MIa1
Karlov, VA1
Savchenko, IuN1
Solovykh, NN2
Shershever, AS1
Shprakh, VV1
Macdonald, RL1
Kelly, KM1
Duval, X1
Chosidow, O1
Semah, F1
Lipsker, D1
Francès, C1
Herson, S1
Gidal, BE1
Garnett, WR1
Ferrie, CD1
Robinson, RO1
Knott, C1
Panayiotopoulos, CP1
Korotkov, AG1
Stolarek, I1
Blacklaw, J1
Forrest, G1
Brodie, MJ1
Reutens, DC1
Duncan, JS1
Patsalos, PN1
Karlsborg, M1
Gram, L1
Uldall, PV1
Sommer, B1
Buchanan, N1
Schapel, G1
Bauer, J1
Helmstaedter, C1
Elger, CE1
Farrell, K1
Connolly, MB1
Munn, R1
Peng, S1
MacWilliam, LM1
Eriksson, AS4
Boreus, LO1
Deleu, D1
Hanssens, Y1
Dulac, O2
Kaminska, A2
Mikati, MA1
Holmes, GL1
Scheen, AJ1
Schapel, GJ1
Wallace, SJ1
Gordon, GS1
Nergårdh, A2
Hoppu, K1
Dravet, C2
Genton, P1
Belmonte, A1
Shakespeare, A1
Simeon, G1
Bélanger, S1
Coulombe, G1
Carmant, L1
Beran, RG1
Berkovic, SF1
Dunagan, FM1
Vajda, FJ1
Danta, G1
Black, AB1
Mackenzie, R1
O'Connor, WT1
Polselli, GM1
Pennisi, EM1
Figà Talamanca, L1
Roberti, R1
Garelli, FF1
Bandinelli, PL1
Gericke, CA1
Picard, F1
de Saint-Martin, A1
Strumia, S1
Marescaux, C1
Hirsch, E1
Barron, TF1
Hunt, SL1
Hoban, TF1
Price, ML1
Kiley, MA1
Smith, SJ1
Knutsson, E1
Kmieć, T1
Jóźwiak, S1
Kuczyński, D1
Karkowska, B1
Bachański, M1
Guye, M1
Bartolomei, F1
Gastaut, JL1
Chauvel, P1
Perucca, E1
Wong, IC1
Mawer, GE1
Lhatoo, SD1
Timmings, PL1
Richens, A1
Stewart, J1
Hughes, E1
Reynolds, EH1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase 3: Metabolism of Lamotrigine During Treatment With Oral Contraceptives[NCT00266149]Phase 310 participants Interventional2003-06-30Terminated
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

19 reviews available for lamotrigine and Convulsive Generalized Seizure Disorder

ArticleYear
A reappraisal of atypical absence seizures in children and adults: therapeutic implications.
    Expert opinion on pharmacotherapy, 2019, Volume: 20, Issue:17

    Topics: Anticonvulsants; Epilepsy, Generalized; Ethosuximide; Humans; Lamotrigine; Lennox Gastaut Syndrome;

2019
Anticonvulsant drugs for generalized tonic-clonic epilepsy.
    Expert opinion on pharmacotherapy, 2017, Volume: 18, Issue:9

    Topics: Acetamides; Anticonvulsants; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Female; Fructose; Humans

2017
Antiepileptic drug monotherapy for epilepsy: a network meta-analysis of individual participant data.
    The Cochrane database of systematic reviews, 2017, 06-29, Volume: 6

    Topics: Adult; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Epilepsies, Parti

2017
Lamotrigine versus valproic acid monotherapy for generalised epilepsy: A meta-analysis of comparative studies.
    Seizure, 2017, Volume: 51

    Topics: Anticonvulsants; Epilepsy, Generalized; Female; Humans; Lamotrigine; Male; Triazines; Valproic Acid

2017
Antiepileptic drug monotherapy for epilepsy: a network meta-analysis of individual participant data.
    The Cochrane database of systematic reviews, 2017, 12-15, Volume: 12

    Topics: Adult; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Epilepsies, Parti

2017
Lamotrigine versus carbamazepine monotherapy for epilepsy: an individual participant data review.
    The Cochrane database of systematic reviews, 2018, 06-28, Volume: 6

    Topics: Adult; Anticonvulsants; Carbamazepine; Child; Epilepsies, Partial; Epilepsy, Generalized; Epilepsy,

2018
Pharmacotherapy for tonic-clonic seizures.
    Expert opinion on pharmacotherapy, 2014, Volume: 15, Issue:10

    Topics: Acetamides; Anticonvulsants; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Fructose; Humans; Lacosa

2014
Lamotrigine versus carbamazepine monotherapy for epilepsy: an individual participant data review.
    The Cochrane database of systematic reviews, 2016, 11-14, Volume: 11

    Topics: Adult; Anticonvulsants; Carbamazepine; Child; Epilepsies, Partial; Epilepsy, Generalized; Epilepsy,

2016
The first line of therapy in a girl with juvenile myoclonic epilepsy: should it be valproate or a new agent?
    Epilepsia, 2009, Volume: 50 Suppl 8

    Topics: Anticonvulsants; Congenital Abnormalities; Delayed-Action Preparations; Drug Design; Epilepsy, Gener

2009
Chronic management of seizures in the syndromes of idiopathic generalized epilepsy.
    Epilepsia, 2003, Volume: 44 Suppl 2

    Topics: Adult; Anticonvulsants; Child; Clinical Trials as Topic; Epilepsy, Generalized; Fructose; Humans; La

2003
Efficacy and tolerability of the new antiepileptic drugs, I: Treatment of new-onset epilepsy: report of the TTA and QSS Subcommittees of the American Academy of Neurology and the American Epilepsy Society.
    Epilepsia, 2004, Volume: 45, Issue:5

    Topics: Acetates; Adolescent; Adult; Age Factors; Amines; Antipsychotic Agents; Carbamazepine; Child; Clinic

2004
Efficacy and tolerability of the new antiepileptic drugs, II: Treatment of refractory epilepsy: report of the TTA and QSS Subcommittees of the American Academy of Neurology and the American Epilepsy Society.
    Epilepsia, 2004, Volume: 45, Issue:5

    Topics: Acetates; Adolescent; Adult; Age Factors; Amines; Anticonvulsants; Carbamazepine; Child; Clinical Tr

2004
Efficacy and tolerability of the new antiepileptic drugs II: treatment of refractory epilepsy: report of the Therapeutics and Technology Assessment Subcommittee and Quality Standards Subcommittee of the American Academy of Neurology and the American Epile
    Neurology, 2004, Apr-27, Volume: 62, Issue:8

    Topics: Acetates; Adult; Amines; Anticonvulsants; Carbamazepine; Child; Clinical Trials as Topic; Cyclohexan

2004
Practical management issues for idiopathic generalized epilepsies.
    Epilepsia, 2005, Volume: 46 Suppl 9

    Topics: Age Factors; Age of Onset; Anticonvulsants; Electric Stimulation Therapy; Epilepsy, Generalized; Hum

2005
Lamotrigine versus carbamazepine monotherapy for epilepsy.
    The Cochrane database of systematic reviews, 2006, Jan-25, Issue:1

    Topics: Adult; Anticonvulsants; Carbamazepine; Child; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized;

2006
Antiepileptic drug mechanisms of action.
    Epilepsia, 1993, Volume: 34 Suppl 5

    Topics: Acetates; Action Potentials; Amines; Anticonvulsants; Calcium Channels; Cyclohexanecarboxylic Acids;

1993
Use of lamotrigine in Lennox-Gastaut and related epilepsy syndromes.
    Journal of child neurology, 1997, Volume: 12 Suppl 1

    Topics: Anticonvulsants; Child; Diagnosis, Differential; Epilepsy; Epilepsy, Generalized; Humans; Lamotrigin

1997
Lamotrigine in absence and primary generalized epilepsies.
    Journal of child neurology, 1997, Volume: 12 Suppl 1

    Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Epilepsy, Absence; Epilepsy, Generalize

1997
The management of refractory idiopathic epilepsies.
    Epilepsia, 2001, Volume: 42 Suppl 3

    Topics: Adolescent; Anticonvulsants; Child; Clinical Protocols; Drug Administration Schedule; Drug Therapy,

2001

Trials

20 trials available for lamotrigine and Convulsive Generalized Seizure Disorder

ArticleYear
The effects of oxcarbazepine, levetiracetam, and lamotrigine on semen quality, sexual function, and sex hormones in male adults with epilepsy.
    Epilepsia, 2018, Volume: 59, Issue:7

    Topics: Adult; Anticonvulsants; Epilepsies, Partial; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Fertilit

2018
Time to 12-month remission and treatment failure for generalised and unclassified epilepsy.
    Journal of neurology, neurosurgery, and psychiatry, 2014, Volume: 85, Issue:6

    Topics: Adolescent; Adult; Anticonvulsants; Child; Electroencephalography; Epilepsy, Generalized; Female; Fr

2014
Imaging the cortical effect of lamotrigine in patients with idiopathic generalized epilepsy: a low-resolution electromagnetic tomography (LORETA) study.
    Epilepsy research, 2008, Volume: 81, Issue:2-3

    Topics: Adolescent; Adult; Anticonvulsants; Brain Mapping; Cerebral Cortex; Child; Electroencephalography; E

2008
[Efficacy and safety of the combined therapy of valproic acid and lamotrigine for epileptics].
    Zhonghua yi xue za zhi, 2012, May-08, Volume: 92, Issue:17

    Topics: Child; Child, Preschool; Drug Therapy, Combination; Epilepsies, Partial; Epilepsy; Epilepsy, Absence

2012
The LAM-SAFE Study: lamotrigine versus carbamazepine or valproic acid in newly diagnosed focal and generalised epilepsies in adolescents and adults.
    Seizure, 2005, Volume: 14, Issue:8

    Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Demography; Epilepsies, Partial; Epilepsy, Genera

2005
[The use of lamotrigine in female patients].
    Der Nervenarzt, 2007, Volume: 78, Issue:8

    Topics: Acne Vulgaris; Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Body Composition; Body W

2007
Effect of lamotrigine on cerebral blood flow in patients with idiopathic generalised epilepsy.
    European journal of nuclear medicine and molecular imaging, 2006, Volume: 33, Issue:6

    Topics: Adolescent; Adult; Anticonvulsants; Brain; Cerebrovascular Circulation; Epilepsy, Generalized; Femal

2006
Lamotrigine adjunctive therapy among children and adolescents with primary generalized tonic-clonic seizures.
    Pediatrics, 2006, Volume: 118, Issue:2

    Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Double-Blind Method; Drug Administratio

2006
Regional effects of lamotrigine on cerebral glucose metabolism in idiopathic generalized epilepsy.
    Archives of neurology, 2006, Volume: 63, Issue:9

    Topics: Adolescent; Adult; Anticonvulsants; Brain Mapping; Cerebral Cortex; Epilepsy, Generalized; Female; F

2006
Evaluation of renal tubular function in children taking anti-epileptic treatment.
    Nephrology (Carlton, Vic.), 2006, Volume: 11, Issue:6

    Topics: Acetylglucosaminidase; Anticonvulsants; Biomarkers; Blood Urea Nitrogen; Carbamazepine; Child; Child

2006
Lamotrigine decreases EEG synchronization in a use-dependent manner in patients with idiopathic generalized epilepsy.
    Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2007, Volume: 118, Issue:4

    Topics: Adolescent; Adult; Anticonvulsants; Brain Mapping; Child; Electroencephalography; Epilepsy, Generali

2007
The SANAD study of effectiveness of valproate, lamotrigine, or topiramate for generalised and unclassifiable epilepsy: an unblinded randomised controlled trial.
    Lancet (London, England), 2007, Mar-24, Volume: 369, Issue:9566

    Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Cost-Benefit Analysis; Epilepsy, Genera

2007
[Lamiktal in the treatment of epilepsy patients].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 1995, Volume: 95, Issue:3

    Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Chronic Disease; Epilepsies, Partial; E

1995
Vigabatrin and lamotrigine in refractory epilepsy.
    Journal of neurology, neurosurgery, and psychiatry, 1994, Volume: 57, Issue:8

    Topics: Anticonvulsants; Double-Blind Method; Drug Monitoring; Drug Therapy, Combination; Epilepsy, Complex

1994
Prospective, open-label, add-on study of lamotrigine in 56 children with intractable generalized epilepsy.
    Pediatric neurology, 1997, Volume: 16, Issue:3

    Topics: Adolescent; Anticonvulsants; Benzodiazepines; Child; Child, Preschool; Drug Therapy, Combination; Ep

1997
The efficacy of lamotrigine in children and adolescents with refractory generalized epilepsy: a randomized, double-blind, crossover study.
    Epilepsia, 1998, Volume: 39, Issue:5

    Topics: Adolescent; Age Factors; Anticonvulsants; Child; Child, Preschool; Cross-Over Studies; Double-Blind

1998
Economic analysis of epilepsy treatment: a cost minimization analysis comparing carbamazepine and lamotrigine in the UK.
    Seizure, 1998, Volume: 7, Issue:2

    Topics: Anticonvulsants; Carbamazepine; Cost Control; Decision Support Techniques; Drug Costs; Epilepsies, P

1998
Double-blind, placebo-controlled, crossover study of lamotrigine in treatment-resistant generalised epilepsy.
    Epilepsia, 1998, Volume: 39, Issue:12

    Topics: Adolescent; Adult; Ambulatory Care; Anticonvulsants; Cross-Over Studies; Double-Blind Method; Drug A

1998
The effect of lamotrigine on epileptiform discharges in young patients with drug-resistant epilepsy.
    Epilepsia, 2001, Volume: 42, Issue:2

    Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Cognition; Double-Blind Method; Electro

2001
[Gabitril as an additive drug in therapy of intractable epileptic seizures in children].
    Neurologia i neurochirurgia polska, 2000, Volume: 34 Suppl 7

    Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Drug Therapy, Combi

2000

Other Studies

58 other studies available for lamotrigine and Convulsive Generalized Seizure Disorder

ArticleYear
Rational therapy with lamotrigine or levetiracetam: Which one to select?
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2022, Volume: 99

    Topics: Anticonvulsants; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Humans; Immunoglobulin E; Lam

2022
Trends in antiseizure medication prescription patterns among all adults, women, and older adults with epilepsy: A German longitudinal analysis from 2008 to 2020.
    Epilepsy & behavior : E&B, 2022, Volume: 130

    Topics: Aged; Anticonvulsants; Benzodiazepines; Carbamazepine; Drug Prescriptions; Epilepsy; Epilepsy, Gener

2022
Efficacy of antiseizure medication in a mouse model of HCN1 developmental and epileptic encephalopathy.
    Epilepsia, 2023, Volume: 64, Issue:1

    Topics: Animals; Anticonvulsants; Epilepsy; Epilepsy, Generalized; Hyperpolarization-Activated Cyclic Nucleo

2023
Lack of association of SCN2A rs17183814 polymorphism with the efficacy of lamotrigine monotherapy in patients with focal epilepsy from Herzegovina area, Bosnia and Herzegovina.
    Epilepsy research, 2019, Volume: 158

    Topics: Adult; Anticonvulsants; Bosnia and Herzegovina; Carbamazepine; Epilepsies, Partial; Epilepsy; Epilep

2019
Treatment of epilepsy in adults: Expert opinion in South Korea.
    Epilepsy & behavior : E&B, 2020, Volume: 105

    Topics: Adult; Aged; Anticonvulsants; Epilepsies, Partial; Epilepsy, Absence; Epilepsy, Generalized; Expert

2020
Pharmacoresponse in genetic generalized epilepsy: a genome-wide association study.
    Pharmacogenomics, 2020, Volume: 21, Issue:5

    Topics: Adolescent; Anticonvulsants; Case-Control Studies; Child; Cohort Studies; Epilepsy, Generalized; Eur

2020
The clinical spectrum of familial and sporadic idiopathic generalized epilepsy.
    Epilepsy research, 2020, Volume: 165

    Topics: Adolescent; Adult; Anticonvulsants; Epilepsy, Generalized; Female; Genetic Predisposition to Disease

2020
Patterns and prognostic markers for treatment response in generalized epilepsies.
    Neurology, 2020, 11-03, Volume: 95, Issue:18

    Topics: Adolescent; Adult; Anticonvulsants; Biomarkers; Drug Resistance; Epilepsy, Generalized; Humans; Lamo

2020
Risk factors of paradoxical reactions to anti-seizure medication in genetic generalized epilepsy.
    Epilepsy research, 2021, Volume: 170

    Topics: Adult; Anticonvulsants; Epilepsy, Generalized; Humans; Lamotrigine; Levetiracetam; Myoclonic Epileps

2021
Antiepileptic Drug Treatment Patterns in Women of Childbearing Age With Epilepsy.
    JAMA neurology, 2019, 07-01, Volume: 76, Issue:7

    Topics: Adolescent; Adult; Anticonvulsants; Anxiety Disorders; Comorbidity; Dissociative Disorders; Epilepsi

2019
Atherosclerotic effects of long-term old and new antiepileptic drugs monotherapy: a cross-sectional comparative study.
    Journal of child neurology, 2015, Volume: 30, Issue:4

    Topics: Adolescent; Anticonvulsants; Carbamazepine; Carotid Arteries; Carotid Intima-Media Thickness; Cross-

2015
Efficacy and safety of lamotrigine monotherapy in children and adolescents with epilepsy.
    European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2009, Volume: 13, Issue:2

    Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Electroencephalography; Epilepsies, Partial; E

2009
Lamotrigine-valproic acid combination therapy for medically refractory epilepsy.
    Epilepsia, 2009, Volume: 50, Issue:3

    Topics: Adolescent; Adult; Age of Onset; Anticonvulsants; Child; Child, Preschool; Dose-Response Relationshi

2009
[Anticonvulsant hypersensitivity syndrome and lamotrigine-associated anticonvulsant hypersensitivity syndrome].
    Revue neurologique, 2009, Volume: 165, Issue:10

    Topics: Adult; Aged; Anticonvulsants; Bipolar Disorder; Drug Eruptions; Drug Hypersensitivity; Eosinophilia;

2009
Epilepsy in Angelman syndrome: a questionnaire-based assessment of the natural history and current treatment options.
    Epilepsia, 2009, Volume: 50, Issue:11

    Topics: Adolescent; Adult; Angelman Syndrome; Anticonvulsants; Child; Child, Preschool; Clonazepam; Comorbid

2009
Neurological and psychiatric aspects of corpus callosum genesis.
    Psychiatria Danubina, 2010, Volume: 22, Issue:2

    Topics: Acrocallosal Syndrome; Adult; Amnesia; Anticonvulsants; Apraxias; Epilepsy, Generalized; Functional

2010
Facial tic associated with lamotrigine in adults.
    Movement disorders : official journal of the Movement Disorder Society, 2010, Jul-30, Volume: 25, Issue:10

    Topics: Adult; Anticonvulsants; Epilepsy, Generalized; Face; Humans; Lamotrigine; Male; Tic Disorders; Triaz

2010
Oral hairy leukoplakia in a patient on long-term anticonvulsant treatment with lamotrigine.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2011, Volume: 111, Issue:5

    Topics: Anticonvulsants; Diagnosis, Differential; Epilepsy, Generalized; Female; Humans; Immunologic Deficie

2011
[Idiopathic generalized epilepsy in young women: choise of treatment strategy].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2012, Volume: 112, Issue:6 Pt 2

    Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Electroencephalography; Epilepsy, Generalized; Fe

2012
Exon-disrupting deletions of NRXN1 in idiopathic generalized epilepsy.
    Epilepsia, 2013, Volume: 54, Issue:2

    Topics: Adult; Age of Onset; Anticonvulsants; Calcium-Binding Proteins; Case-Control Studies; Cell Adhesion

2013
Mild generalized epilepsy and developmental disorder associated with large inv dup(15).
    Epilepsia, 2002, Volume: 43, Issue:9

    Topics: Adult; Age of Onset; Angelman Syndrome; Anticonvulsants; Chromosome Aberrations; Chromosome Inversio

2002
Non convulsive status epilepticus after replacement of valproate with lamotrigine.
    Journal of neurology, 2002, Volume: 249, Issue:10

    Topics: Adult; Aged; Anticoagulants; Benzodiazepines; Electroencephalography; Epilepsy, Generalized; Female;

2002
Neurotoxicity following addition of intravenous valproate to lamotrigine therapy.
    Neurology, 2003, Jun-24, Volume: 60, Issue:12

    Topics: Administration, Oral; Adult; Ammonia; Anticonvulsants; Confusion; Drug Interactions; Drug Therapy, C

2003
Lamotrigine-induced common variable immune deficiency.
    Neurology, 2004, Mar-09, Volume: 62, Issue:5

    Topics: Common Variable Immunodeficiency; Epilepsy, Generalized; Excitatory Amino Acid Antagonists; Humans;

2004
Recurrent severe aseptic meningitis after exposure to lamotrigine in a patient with systemic lupus erythematosus.
    Epilepsia, 2005, Volume: 46, Issue:2

    Topics: Adolescent; Anticonvulsants; Comorbidity; Epilepsy, Generalized; Female; Humans; Lamotrigine; Lupus

2005
The use of lamotrigine, vigabatrin and gabapentin as add-on therapy in intractable epilepsy of childhood.
    Seizure, 2005, Volume: 14, Issue:2

    Topics: Amines; Anticonvulsants; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Drug Therapy, Combina

2005
Lamotrigine-induced rash--worth a rechallenge.
    Acta neurologica Scandinavica, 2005, Volume: 111, Issue:3

    Topics: Anticonvulsants; Epilepsy, Generalized; Exanthema; Humans; Lamotrigine; Retrospective Studies; Risk

2005
[Epileptic seizures during childbirth in a patient with idiopathic generalised epilepsy].
    Nederlands tijdschrift voor geneeskunde, 2005, Jun-18, Volume: 149, Issue:25

    Topics: Adult; Anticonvulsants; Cesarean Section; Clonazepam; Diazepam; Epilepsy; Epilepsy, Generalized; Epi

2005
An audit of lamotrigine, levetiracetam and topiramate usage for epilepsy in a district general hospital.
    Seizure, 2005, Volume: 14, Issue:6

    Topics: Adult; Aged; Anticonvulsants; Cohort Studies; Drug Utilization; Epilepsy; Epilepsy, Generalized; Fem

2005
Active control trials for epilepsy: avoiding bias in head-to-head trials.
    Neurology, 2006, May-09, Volume: 66, Issue:9

    Topics: Anticonvulsants; Bias; Carbamazepine; Control Groups; Dose-Response Relationship, Drug; Drug Adminis

2006
Choosing a first drug treatment for epilepsy after SANAD: randomized controlled trials, systematic reviews, guidelines and treating patients.
    Epilepsia, 2007, Volume: 48, Issue:7

    Topics: Anticonvulsants; Carbamazepine; Cost-Benefit Analysis; Drug Costs; Drug Industry; Epilepsies, Partia

2007
Lamotrigine intoxication provoking status epilepticus in an adult with localization-related epilepsy.
    Archives of neurology, 2007, Volume: 64, Issue:9

    Topics: Adult; Anticonvulsants; Electroencephalography; Epilepsy, Generalized; Female; Humans; Lamotrigine;

2007
Lamotrigine versus carbamazepine in epilepsy.
    Lancet (London, England), 1995, May-20, Volume: 345, Issue:8960

    Topics: Adult; Anticonvulsants; Clonazepam; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Humans; Lamotrigi

1995
Perspective on lamotrigine.
    The Annals of pharmacotherapy, 1995, Volume: 29, Issue:2

    Topics: Adult; Anticonvulsants; Clinical Trials, Phase III as Topic; Epilepsies, Partial; Epilepsy; Epilepsy

1995
Lamotrigine as an add-on drug in typical absence seizures.
    Acta neurologica Scandinavica, 1995, Volume: 91, Issue:3

    Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy, Ge

1995
[The use of Lamiktal in treating epilepsy in children and adolescents].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 1994, Volume: 94, Issue:4

    Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Chronic Disease; Drug Evaluation; Drug

1994
Lamotrigine for epilepsy.
    The Medical letter on drugs and therapeutics, 1995, Mar-17, Volume: 37, Issue:944

    Topics: Animals; Anticonvulsants; Clinical Trials as Topic; Drug Interactions; Drug Therapy, Combination; Ep

1995
Disabling tremor after lamotrigine with sodium valproate.
    Lancet (London, England), 1993, Jul-17, Volume: 342, Issue:8864

    Topics: Anticonvulsants; Drug Interactions; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Humans; Lamotrigi

1993
[Lamotrigine treatment of 92 patients with intractable epilepsy].
    Ugeskrift for laeger, 1996, Apr-01, Volume: 158, Issue:14

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Fema

1996
[Treatment of childhood epilepsy with lamotrigine. An evaluation of efficacy in different types of epilepsy].
    Ugeskrift for laeger, 1996, Apr-01, Volume: 158, Issue:14

    Topics: Adolescent; Anticonvulsants; Child; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Female; Hu

1996
Lamotrigine: clinical experience in 200 patients with epilepsy with follow-up to four years.
    Seizure, 1996, Volume: 5, Issue:3

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Brain Damage, Chronic; Child; Child, Preschool; Drug Thera

1996
A survey comparing lamotrigine and vigabatrin in everyday clinical practice.
    Seizure, 1996, Volume: 5, Issue:4

    Topics: Anticonvulsants; Electroencephalography; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Epile

1996
Nonconvulsive status epilepticus with generalized 'fast activity'.
    Seizure, 1997, Volume: 6, Issue:1

    Topics: Alpha Rhythm; Anticonvulsants; Cerebral Cortex; Diagnosis, Differential; Drug Therapy, Combination;

1997
No increase in carbamazepine-10,11-epoxide during addition of lamotrigine treatment in children.
    Therapeutic drug monitoring, 1997, Volume: 19, Issue:5

    Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Drug Interactions; Drug Monitoring; Epilep

1997
Loss of aura in lamotrigine-treated epilepsy.
    Lancet (London, England), 1997, Dec-13, Volume: 350, Issue:9093

    Topics: Adolescent; Adult; Anticonvulsants; Epilepsies, Partial; Epilepsy, Generalized; Female; Humans; Lamo

1997
[Lamotrigine (Lamictal)].
    Revue medicale de Liege, 1997, Volume: 52, Issue:11

    Topics: Anticonvulsants; Brain; Child; Child, Preschool; Drug Combinations; Drug Eruptions; Epilepsies, Part

1997
A survey of lamotrigine and vigabatrin treatment in children with severe epilepsy.
    Seizure, 1997, Volume: 6, Issue:6

    Topics: Adolescent; Anticonvulsants; Child; Drug Therapy, Combination; Electroencephalography; Epilepsies, P

1997
Lamotrigine and seizure aggravation in severe myoclonic epilepsy.
    Epilepsia, 1998, Volume: 39, Issue:5

    Topics: Acute Disease; Adolescent; Adult; Anticonvulsants; Child; Comorbidity; Drug Therapy, Combination; Ep

1998
Role of vigabatrin and lamotrigine in treatment of childhood epileptic syndromes.
    Epilepsia, 1998, Volume: 39, Issue:8

    Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Child; Child, Preschool; Drug Therapy, Combination;

1998
Analysis of CSF amino acids in young patients with generalised refractory epilepsy during an add-on study with lamotrigine.
    Epilepsy research, 1999, Volume: 34, Issue:1

    Topics: Adolescent; Adult; Amino Acids; Anticonvulsants; Aspartic Acid; Child; Child, Preschool; Drug Resist

1999
Psychotic disorder after lamotrigine.
    Italian journal of neurological sciences, 1998, Volume: 19, Issue:2

    Topics: Adult; Anticonvulsants; Epilepsy, Generalized; Humans; Lamotrigine; Male; Psychoses, Substance-Induc

1998
Efficacy of lamotrigine in idiopathic generalized epilepsy syndromes: a video-EEG-controlled, open study.
    Epileptic disorders : international epilepsy journal with videotape, 1999, Volume: 1, Issue:3

    Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug

1999
Lamotrigine monotherapy in children.
    Pediatric neurology, 2000, Volume: 23, Issue:2

    Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Epilepsies, Partial; Epilepsy; Epilepsy

2000
Idiopathic generalized epilepsy presenting with hemiconvulsive seizures.
    Epilepsia, 2000, Volume: 41, Issue:12

    Topics: Adolescent; Anticonvulsants; Child; Comorbidity; Electroencephalography; Epilepsy, Frontal Lobe; Epi

2000
Absence epilepsy with fast rhythmic discharges during sleep: an intermediary form of generalized epilepsy?
    Epilepsia, 2001, Volume: 42, Issue:3

    Topics: Adult; Age of Onset; Anticonvulsants; Cerebral Cortex; Child; Child, Preschool; Diagnosis, Different

2001
A pharmacoepidemiologic study of factors influencing the outcome of treatment with lamotrigine in chronic epilepsy.
    Epilepsia, 2001, Volume: 42, Issue:10

    Topics: Anticonvulsants; Chronic Disease; Drug Therapy, Combination; Electroencephalography; England; Epilep

2001
Lamotrigine in primary generalised epilepsy.
    Lancet (London, England), 1992, May-23, Volume: 339, Issue:8804

    Topics: Anticonvulsants; Epilepsies, Partial; Epilepsy, Generalized; Humans; Lamotrigine; Triazines

1992
Lamotrigine for generalised epilepsies.
    Lancet (London, England), 1992, Nov-14, Volume: 340, Issue:8829

    Topics: Adult; Anticonvulsants; Drug Resistance; Epilepsies, Partial; Epilepsy, Generalized; Humans; Lamotri

1992