lamotrigine has been researched along with Convulsions, Grand Mal in 41 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Features of Lamotrigine poisoning are not clearly described in children." | 7.74 | Lamotrigine poisoning presenting as seizures: a case of deliberate poisoning. ( Rabb, L; Roper, H; Willis, T, 2007) |
| "Vigabatrin is a specific and irreversible inhibitor of the enzyme gamma-amino-butyric-acid (GABA) transferase." | 6.39 | [Vigabatrin and lamotrigin: experiences with 2 new anticonvulsants in the Swiss epilepsy clinic]. ( Krämer, G; Vogt, H, 1995) |
| "To compare the effects of carbamazepine and lamotrigine monotherapy for people with partial onset seizures or generalized onset tonic-clonic seizures." | 4.83 | A meta-analysis of individual patient responses to lamotrigine or carbamazepine monotherapy. ( Chadwick, DW; Gamble, C; Marson, AG; Williamson, PR, 2006) |
| "Features of Lamotrigine poisoning are not clearly described in children." | 3.74 | Lamotrigine poisoning presenting as seizures: a case of deliberate poisoning. ( Rabb, L; Roper, H; Willis, T, 2007) |
| "During her first pregnancy, a 37-year-old woman with idiopathic generalised epilepsy that was adequately controlled with lamotrigine experienced a series of epileptic seizures following an elective caesarean section." | 3.73 | [Epileptic seizures during childbirth in a patient with idiopathic generalised epilepsy]. ( Bloem, BR; Renier, WO; Voermans, NC; Zwarts, MJ, 2005) |
| "The anticonvulsant actions of lamotrigine and phenytoin against pentylenetetrazol-induced seizures were compared in laboratory rats during ontogenesis." | 3.68 | Anticonvulsant action of lamotrigine during ontogenesis in rats. ( Kubová, H; Mares, P; Stanková, L, 1992) |
| "Lamotrigine was introduced and titrated using a schedule based on the patients' age and concurrent antiepileptic drug regimen." | 2.72 | Lamotrigine adjunctive therapy among children and adolescents with primary generalized tonic-clonic seizures. ( Hammer, AE; Kerls, SP; Messenheimer, JA; Trevathan, E; Vuong, A, 2006) |
| "Lamotrigine was significantly less likely to be withdrawn than carbamazepine but the results for time to first seizure suggested that carbamazepine may be superior in terms of seizure control." | 2.53 | Lamotrigine versus carbamazepine monotherapy for epilepsy: an individual participant data review. ( Marson, AG; Nolan, SJ; Tudur Smith, C; Weston, J, 2016) |
| "Occurrence of generalized tonic-clonic seizures (GTCS) is one of the most important risk factors of seizure-related complications and comorbidities in patients with epilepsy." | 2.50 | Pharmacotherapy for tonic-clonic seizures. ( Rheims, S; Ryvlin, P, 2014) |
| "Rash was the only adverse effect causing discontinuation (N = 7)." | 2.46 | Lamotrigine adjunctive therapy for refractory generalized tonic-clonic seizures. ( Leong, K; Marson, AG; Tjia-Leong, E, 2010) |
| "Vigabatrin is a specific and irreversible inhibitor of the enzyme gamma-amino-butyric-acid (GABA) transferase." | 2.39 | [Vigabatrin and lamotrigin: experiences with 2 new anticonvulsants in the Swiss epilepsy clinic]. ( Krämer, G; Vogt, H, 1995) |
| "Epileptic seizures were primary tonic-clonic (67." | 1.51 | Accidental injuries in patients with generalized tonic-clonic seizures. A multicenter, observational, cross-sectional study (QUIN-GTC study). ( Abraira, L; Iniesta, M; Puig, J; Salas-Puig, X, 2019) |
| "An epileptic seizure is reported in a 38-year-old woman, known to be an epileptic patient." | 1.37 | Epileptic seizure induced by fennel essential oil. ( Skalli, S; Soulaymani Bencheikh, R, 2011) |
| "Absence status was aggravated with carbamazepine and generalised tonic-clonic seizures were not controlled with ethosuximide." | 1.36 | Unilateral continuous subclinical paroxysmal activity: an unusual finding in a patient with recurrent absence status. ( Genton, P; Velizarova, R, 2010) |
| "Lamotrigine is an anti-epileptic drug considered as a first-line therapy in idiopathic generalised epilepsy." | 1.33 | [Exacerbation of tonicoclonic seizures in a juvenile myoclonic epileptic taking lamotrigine]. ( Guillon, B; Maiga, Y; Nogues, B, 2006) |
| "Juvenile myoclonic epilepsy is a relatively common, though under diagnosed, form of epilepsy that commences in adolescence." | 1.29 | Juvenile myoclonic epilepsy. ( Buchanan, N, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (26.83) | 18.2507 |
| 2000's | 13 (31.71) | 29.6817 |
| 2010's | 15 (36.59) | 24.3611 |
| 2020's | 2 (4.88) | 2.80 |
| Authors | Studies |
|---|---|
| Yaryari, AM | 1 |
| Mazdeh, M | 1 |
| Mohammadi, M | 1 |
| Haghi, AR | 1 |
| Ghiasian, M | 1 |
| Mehrpooya, M | 1 |
| Bresnahan, R | 1 |
| Panebianco, M | 1 |
| Marson, AG | 5 |
| Sawicka, KM | 1 |
| Załuska, K | 1 |
| Wawryniuk, A | 1 |
| Załuska-Patel, K | 1 |
| Szczyrek, M | 1 |
| Drop, B | 1 |
| Daniluk, J | 1 |
| Szpringer, M | 1 |
| Żółkowska, D | 1 |
| Łuszczki, JJ | 1 |
| Coppola, G | 1 |
| Piccorossi, A | 1 |
| Operto, FF | 1 |
| Verrotti, A | 1 |
| Wu, D | 1 |
| Chen, L | 1 |
| Ji, F | 1 |
| Si, Y | 1 |
| Sun, H | 1 |
| Nevitt, SJ | 1 |
| Tudur Smith, C | 2 |
| Weston, J | 2 |
| Salas-Puig, X | 1 |
| Iniesta, M | 1 |
| Abraira, L | 1 |
| Puig, J | 1 |
| Rheims, S | 1 |
| Ryvlin, P | 1 |
| Nolan, SJ | 1 |
| Taillia, H | 1 |
| Alla, P | 1 |
| Fournier, B | 1 |
| Bounolleau, P | 1 |
| Ouologem, M | 1 |
| Ricard, D | 1 |
| Sallansonnet-Froment, M | 1 |
| de Greslan, T | 1 |
| Renard, JL | 1 |
| Vining, EP | 1 |
| Muzyk, A | 1 |
| Gala, G | 1 |
| Kahn, DA | 1 |
| Velizarova, R | 1 |
| Genton, P | 1 |
| Steinbaugh, L | 1 |
| Szaflarski, JP | 1 |
| Tjia-Leong, E | 1 |
| Leong, K | 1 |
| Veerapandiyan, A | 1 |
| Gallentine, WB | 1 |
| Winchester, SA | 1 |
| Baker, J | 1 |
| Kansagra, SM | 1 |
| Mikati, MA | 1 |
| Perucca, E | 1 |
| Skalli, S | 1 |
| Soulaymani Bencheikh, R | 1 |
| Famularo, G | 1 |
| De Simone, C | 1 |
| Minisola, G | 1 |
| Voermans, NC | 1 |
| Zwarts, MJ | 1 |
| Renier, WO | 1 |
| Bloem, BR | 1 |
| Biton, V | 1 |
| Sackellares, JC | 1 |
| Vuong, A | 2 |
| Hammer, AE | 2 |
| Barrett, PS | 1 |
| Messenheimer, JA | 2 |
| Surve, TY | 1 |
| Mittal, G | 1 |
| Khadse, SS | 1 |
| Khanna, SA | 1 |
| Gamble, C | 1 |
| Williamson, PR | 1 |
| Chadwick, DW | 1 |
| Trevathan, E | 1 |
| Kerls, SP | 1 |
| Maiga, Y | 1 |
| Nogues, B | 1 |
| Guillon, B | 1 |
| Bilo, L | 1 |
| Meo, R | 1 |
| Fulvia de Leva, M | 1 |
| Willis, T | 1 |
| Roper, H | 1 |
| Rabb, L | 1 |
| Greiner, C | 1 |
| Wittmann, M | 1 |
| Haen, E | 1 |
| Rosoff, DM | 1 |
| Buchanan, N | 2 |
| Nadarajah, J | 1 |
| Duggan, L | 1 |
| Duval, X | 1 |
| Chosidow, O | 1 |
| Semah, F | 1 |
| Lipsker, D | 1 |
| Francès, C | 1 |
| Herson, S | 1 |
| Vogt, H | 1 |
| Krämer, G | 1 |
| Reutens, DC | 1 |
| Duncan, JS | 1 |
| Patsalos, PN | 1 |
| Schapel, G | 1 |
| Chadwick, D | 1 |
| Bauer, J | 1 |
| Helmstaedter, C | 1 |
| Elger, CE | 1 |
| Fearnside, M | 1 |
| Shakespeare, A | 1 |
| Simeon, G | 1 |
| Briassoulis, G | 1 |
| Kalabalikis, P | 1 |
| Tamiolaki, M | 1 |
| Hatzis, T | 1 |
| French, JA | 1 |
| Stanková, L | 1 |
| Kubová, H | 1 |
| Mares, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Multi-Center, Double-Blind, Randomized, Placebo-Controlled, Parallel-Group Evaluation of Lamotrigine Adjunctive Therapy in Subjects Wtih Primary Generalized Tonic-Clonic Seizures[NCT00043901] | Phase 4 | 141 participants (Actual) | Interventional | 2000-12-01 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
10 reviews available for lamotrigine and Convulsions, Grand Mal
| Article | Year |
|---|---|
Lamotrigine add-on therapy for drug-resistant generalised tonic-clonic seizures.
Topics: Anticonvulsants; Chemotherapy, Adjuvant; Dizziness; Drug Eruptions; Drug Resistant Epilepsy; Epileps | 2020 |
Anticonvulsant drugs for generalized tonic-clonic epilepsy.
Topics: Acetamides; Anticonvulsants; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Female; Fructose; Humans | 2017 |
Lamotrigine versus carbamazepine monotherapy for epilepsy: an individual participant data review.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Epilepsies, Partial; Epilepsy, Generalized; Epilepsy, | 2018 |
Pharmacotherapy for tonic-clonic seizures.
Topics: Acetamides; Anticonvulsants; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Fructose; Humans; Lacosa | 2014 |
Lamotrigine versus carbamazepine monotherapy for epilepsy: an individual participant data review.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Epilepsies, Partial; Epilepsy, Generalized; Epilepsy, | 2016 |
Adjunctive therapy for the treatment of primary generalized tonic-clonic seizures: focus on once-daily lamotrigine.
Topics: Adult; Anticonvulsants; Child; Delayed-Action Preparations; Epilepsy, Tonic-Clonic; Humans; Lamotrig | 2010 |
Lamotrigine adjunctive therapy for refractory generalized tonic-clonic seizures.
Topics: Anticonvulsants; Chemotherapy, Adjuvant; Drug Eruptions; Epilepsy, Tonic-Clonic; Exanthema; Humans; | 2010 |
A meta-analysis of individual patient responses to lamotrigine or carbamazepine monotherapy.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Disease-Free Survival; Double-Blind Method; Epilepsies | 2006 |
[Vigabatrin and lamotrigin: experiences with 2 new anticonvulsants in the Swiss epilepsy clinic].
Topics: 4-Aminobutyrate Transaminase; Adult; Anticonvulsants; Child; Drug Therapy, Combination; Epilepsies, | 1995 |
The role of new antiepileptic drugs.
Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epilepsies, Partial; Epilepsy; Epi | 2001 |
4 trials available for lamotrigine and Convulsions, Grand Mal
| Article | Year |
|---|---|
The effects of oxcarbazepine, levetiracetam, and lamotrigine on semen quality, sexual function, and sex hormones in male adults with epilepsy.
Topics: Adult; Anticonvulsants; Epilepsies, Partial; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Fertilit | 2018 |
Double-blind, placebo-controlled study of lamotrigine in primary generalized tonic-clonic seizures.
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Disorders of Excessive Somnolence; Dizz | 2005 |
Lamotrigine adjunctive therapy among children and adolescents with primary generalized tonic-clonic seizures.
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Double-Blind Method; Drug Administratio | 2006 |
Economic analysis of epilepsy treatment: a cost minimization analysis comparing carbamazepine and lamotrigine in the UK.
Topics: Anticonvulsants; Carbamazepine; Cost Control; Decision Support Techniques; Drug Costs; Epilepsies, P | 1998 |
27 other studies available for lamotrigine and Convulsions, Grand Mal
| Article | Year |
|---|---|
Evaluation of serum levels of asprosin and other metabolic profiles in patients with idiopathic tonic-clonic generalized epilepsy on treatment with valproic acid.
Topics: Adult; Anticonvulsants; Blood Glucose; Body Mass Index; Body Weights and Measures; Cross-Sectional S | 2022 |
Ivabradine attenuates the anticonvulsant potency of lamotrigine, but not that of lacosamide, pregabalin and topiramate in the tonic-clonic seizure model in mice.
Topics: Acetamides; Animals; Anticonvulsants; Benzazepines; Brain; Cardiovascular Agents; Disease Models, An | 2017 |
Accidental injuries in patients with generalized tonic-clonic seizures. A multicenter, observational, cross-sectional study (QUIN-GTC study).
Topics: Accidental Injuries; Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Cross-Sectional St | 2019 |
[Anticonvulsant hypersensitivity syndrome and lamotrigine-associated anticonvulsant hypersensitivity syndrome].
Topics: Adult; Aged; Anticonvulsants; Bipolar Disorder; Drug Eruptions; Drug Hypersensitivity; Eosinophilia; | 2009 |
Ethosuximide in childhood absence epilepsy--older and better.
Topics: Anticonvulsants; Child; Diagnosis, Differential; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Ethosuxi | 2010 |
Use of lamotrigine in a patient with a clozapine-related seizure.
Topics: Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Clozapine; Dose-Response Relationship, Drug | 2010 |
Unilateral continuous subclinical paroxysmal activity: an unusual finding in a patient with recurrent absence status.
Topics: Adult; Anticonvulsants; Brain; Carbamazepine; Diagnosis, Differential; Dose-Response Relationship, D | 2010 |
Oculogyric crises secondary to lamotrigine overdosage.
Topics: Adult; Anticonvulsants; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Overdose; Dr | 2011 |
A young woman with recurring seizures.
Topics: Adolescent; Anticonvulsants; Area Under Curve; Electroencephalography; Epilepsy, Tonic-Clonic; Femal | 2011 |
Epileptic seizure induced by fennel essential oil.
Topics: Adult; Anticonvulsants; Epilepsy; Epilepsy, Tonic-Clonic; Female; Foeniculum; Humans; Lamotrigine; O | 2011 |
Stevens-Johnson syndrome associated with single high dose of lamotrigine in a patient taking valproate.
Topics: Adult; Anticonvulsants; Drug Interactions; Epilepsy, Tonic-Clonic; Humans; Lamotrigine; Male; Steven | 2005 |
[Epileptic seizures during childbirth in a patient with idiopathic generalised epilepsy].
Topics: Adult; Anticonvulsants; Cesarean Section; Clonazepam; Diazepam; Epilepsy; Epilepsy, Generalized; Epi | 2005 |
Epilepsy with myoclonic absences.
Topics: Anticonvulsants; Child; Drug Therapy, Combination; Electroencephalography; Epilepsy, Tonic-Clonic; F | 2006 |
[Exacerbation of tonicoclonic seizures in a juvenile myoclonic epileptic taking lamotrigine].
Topics: Adult; Anticonvulsants; Electroencephalography; Epilepsy, Tonic-Clonic; Humans; Lamotrigine; Male; M | 2006 |
Levetiracetam in idiopathic generalised epilepsy and porphyria cutanea tarda.
Topics: Administration, Oral; Anticonvulsants; Clonazepam; Drug Therapy, Combination; Epilepsy, Tonic-Clonic | 2006 |
Lamotrigine poisoning presenting as seizures: a case of deliberate poisoning.
Topics: Anticonvulsants; Diagnosis, Differential; Dose-Response Relationship, Drug; Epilepsy, Tonic-Clonic; | 2007 |
Lamotrigine serum concentrations under valproate comedication: "contraindication" or "safe combination"? A case report.
Topics: Adult; Anticonvulsants; Antimanic Agents; Chromatography, High Pressure Liquid; Contraindications; D | 2007 |
Another case of extended-release bupropion-induced seizure.
Topics: Adult; Anticonvulsants; Antidepressive Agents, Second-Generation; Bupropion; Clonazepam; Delayed-Act | 2008 |
Juvenile myoclonic epilepsy.
Topics: Adolescent; Age of Onset; Animals; Anticonvulsants; Child; Circadian Rhythm; Clonazepam; Cricetinae; | 1995 |
A missed diagnosis. A missed opportunity for community integration.
Topics: Adult; Anticonvulsants; Combined Modality Therapy; Diagnosis, Differential; Electroencephalography; | 1995 |
Lamotrigine versus carbamazepine in epilepsy.
Topics: Adult; Anticonvulsants; Clonazepam; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Humans; Lamotrigi | 1995 |
Disabling tremor after lamotrigine with sodium valproate.
Topics: Anticonvulsants; Drug Interactions; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Humans; Lamotrigi | 1993 |
A survey comparing lamotrigine and vigabatrin in everyday clinical practice.
Topics: Anticonvulsants; Electroencephalography; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Epile | 1996 |
Nonconvulsive status epilepticus with generalized 'fast activity'.
Topics: Alpha Rhythm; Anticonvulsants; Cerebral Cortex; Diagnosis, Differential; Drug Therapy, Combination; | 1997 |
Lamotrigine after corpus callosotomy.
Topics: Adult; Anticonvulsants; Child; Combined Modality Therapy; Corpus Callosum; Electroencephalography; E | 1997 |
Lamotrigine childhood overdose.
Topics: Anticonvulsants; Child, Preschool; Drug Overdose; Epilepsy, Tonic-Clonic; Gastric Lavage; Humans; La | 1998 |
Anticonvulsant action of lamotrigine during ontogenesis in rats.
Topics: Aging; Animals; Anticonvulsants; Epilepsy, Tonic-Clonic; Injections, Intraperitoneal; Lamotrigine; M | 1992 |